| Entry |
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| Name |
beta-Ala-His dipeptidase;
serum carnosinase
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Dipeptidases
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| Reaction(IUBMB) |
Preferential hydrolysis of the beta-Ala!His dipeptide (carnosine), and also anserine, Xaa!His dipeptides and other dipeptides including homocarnosine [RN: R01166 R03288]
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| Reaction(KEGG) |
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| Comment |
Present in the serum of humans and higher primates, but not in the serum of other mammals. Activated by Cd2+ and citrate. Belongs in peptidase family M20.
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| History |
EC 3.4.13.20 created 1992
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| Pathway |
| ec00330 | Arginine and proline metabolism |
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| Orthology |
| K05604 | beta-Ala-His dipeptidase |
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| Genes |
» show all
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| Reference |
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| Authors |
Lenney JF, George RP, Weiss AM, Kucera CM, Chan PW, Rinzler GS. |
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| Title |
Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Jackson MC, Kucera CM, Lenney JF. |
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| Title |
Purification and properties of human serum carnosinase. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.13.20 |
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