KEGG   ENZYME: 3.4.14.2
Entry
EC 3.4.14.2                 Enzyme                                 
Name
dipeptidyl-peptidase II;
dipeptidyl aminopeptidase II;
dipeptidyl arylamidase II;
carboxytripeptidase;
dipeptidyl peptidase II;
DAP II;
dipeptidyl(amino)peptidase II;
dipeptidylarylamidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Dipeptidyl-peptidases and tripeptidyl-peptidases
Reaction(IUBMB)
Release of an N-terminal dipeptide, Xaa-Yaa!, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides
Comment
A lysosomal serine-type peptidase in family S28 (Pro-X carboxypeptidase family); maximally active at acidic pH
History
EC 3.4.14.2 created 1978
Orthology
K01276  dipeptidyl-peptidase II
Genes
HSA29952(DPP7)
PPS100976342(DPP7)
GGO101136044(DPP7)
PON100174214(DPP7)
PPYG129044751(DPP7)
NLE100595263(DPP7)
HMH116475910(DPP7)
MCC721595(DPP7)
MCF101867244(DPP7)
MTHB126936964
MNI105471964(DPP7)
CSAB103239581(DPP7)
CATY105580608(DPP7)
PANU101009717 116272657
TGE112617564(DPP7)
MLEU105543279(DPP7)
RRO104669635(DPP7)
RBB108542890(DPP7)
TFN117099114(DPP7)
PTEH111553016(DPP7)
CANG105522685(DPP7)
CJC100413498(DPP7)
SBQ101032597(DPP7)
CIMI108287260(DPP7)
ANAN105712239(DPP7)
CSYR103269508(DPP7)
MMUR105882253(DPP7)
LCAT123645583(DPP7)
PCOQ105818711(DPP7)
OGA100947897(DPP7)
MMU83768(Dpp7)
MCAL110285412(Dpp7)
MPAH110318817(Dpp7)
RNO83799(Dpp7)
MCOC116089812(Dpp7)
ANU117711512(Dpp7)
MUN110550552 110557034(Dpp7)
CGE100756223(Dpp7)
MAUA101826833(Dpp7)
PROB127222591(Dpp7)
PLEU114692782(Dpp7)
MORG121462858(Dpp7)
MFOT126509402
AAMP119819215(Dpp7)
NGI103741174(Dpp7)
HGL101724543(Dpp7)
CPOC100716276(Dpp7)
CCAN109697988(Dpp7)
DORD105995573(Dpp7)
DSP122099710(Dpp7)
PLOP125345283 125351535(Dpp7)
NCAR124964529
MMMA107159193(Dpp7)
OPI101527332(DPP7)
TUP102470111(DPP7)
GVR103593510(DPP7)
CFA607003(DPP7)
CLUD112677481(DPP7)
VVP112911406(DPP7)
VLG121473433(DPP7)
NPO129509845(DPP7)
AML100467965(DPP7)
UMR103675309(DPP7)
UAH113249879(DPP7)
UAR123796321(DPP7)
ELK111145784
LLV125083758
MPUF101685625(DPP7)
MLK131813070(DPP7)
NVS122917073(DPP7)
ORO101379800(DPP7)
EJU114201770(DPP7)
ZCA113934598(DPP7)
NSU110581236(DPP7)
LWW102729350(DPP7)
FCA101095966(DPP7)
PYU121020232(DPP7)
PCOO112860948(DPP7)
PBG122474767(DPP7)
PVIV125150299(DPP7)
LRUF124522355
PTG102948665(DPP7)
PPAD109260264(DPP7)
PUC125923639
AJU106989098
HHV120227605(DPP7)
BTA100125760(DPP7)
BOM102277526(DPP7)
BBUB102402382(DPP7)
CHX102182320(DPP7)
OAS105605898(DPP7)
BTAX128055114(DPP7)
MBEZ129539520(DPP7)
SSC100626630(DPP7)
CFR102514636(DPP7)
CBAI105073395(DPP7)
CDK105106184(DPP7)
VPC102533086(DPP7)
BACU103002313(DPP7)
BMUS118897124(DPP7)
LVE103077546(DPP7)
OOR101274898(DPP7)
DLE111176993(DPP7)
PCAD102988127(DPP7)
PSIU116756117(DPP7)
NASI112411356(DPP7)
ECB100059924(DPP7)
EPZ103568010(DPP7)
EAI106845520(DPP7)
MYD102751478(DPP7)
MMYO118655272(DPP7)
PKL118707093(DPP7)
EFUS103296100(DPP7)
MNA107536150(DPP7)
DRO112306462(DPP7)
SHON118980097(DPP7)
AJM119036098(DPP7)
PDIC114507924(DPP7)
PHAS123823471(DPP7)
MMF118629639(DPP7)
PPAM129079518(DPP7)
HAI109381795(DPP7)
RFQ117032554(DPP7)
PALE102890830(DPP7)
PGIG120599825(DPP7)
PVP105298565(DPP7)
RAY107503091(DPP7)
MJV108406834(DPP7)
TOD119231169(DPP7)
SARA101558615(DPP7)
SETR126020952(DPP7)
LAV100664342(DPP7)
TMU101354737
ETF101638848(DPP7)
DNM101440624(DPP7)
MDO100022760(DPP7)
GAS123235145(DPP7)
SHR100918941(DPP7)
AFZ127549105
PCW110205293(DPP7)
TVP118844096(DPP7)
OAA100082054(DPP7)
GGA417297(DPP7)
PCOC116234099(DPP7)
MGP100543847(DPP7)
CJO107321630(DPP7)
TPAI128079776(DPP7)
LMUT125702408(DPP7)
NMEL110407015(DPP7)
APLA101791397(DPP7)
ACYG106037124(DPP7)
CATA118260739(DPP7)
AFUL116497046(DPP7)
TGU100226334(DPP7)
LSR110472182(DPP7)
SCAN103819204(DPP7)
PMOA120507336(DPP7)
OTC121336948(DPP7)
PRUF121357497(DPP7)
GFR102031390(DPP7)
FAB101815871(DPP7)
CCW104688194(DPP7)
CBRC103625038(DPP7)
ETL114064161(DPP7)
ZAB102067383(DPP7)
ZLE135455018(DPP7)
ACHL103807246(DPP7)
SVG106855973(DPP7)
MMEA130584230(DPP7)
HRT120761821(DPP7)
FPG101914257(DPP7)
FCH102051827(DPP7)
CLV102083967(DPP7)
EGZ104123973(DPP7)
NNI104018392(DPP7)
PCRI104038704(DPP7)
PLET104628618(DPP7)
EHS104514334(DPP7)
PCAO104043330(DPP7)
ACUN113486638(DPP7)
TALA104359834(DPP7)
PADL103915511(DPP7)
AFOR103908303(DPP7)
ACHC115334794(DPP7)
HALD104313580(DPP7)
HLE104830002(DPP7)
AGEN126052504
GCL127023822
CCRI104165546(DPP7)
CSTI104557095(DPP7)
MUI104547181(DPP7)
BREG104633500(DPP7)
FGA104081355(DPP7)
GSTE104258526(DPP7)
LDI104339998(DPP7)
MNB103781849(DPP7)
OHA104329736(DPP7)
NNT104411381(DPP7)
SHAB115616924(DPP7)
DPUB104300188(DPP7)
PGUU104466829(DPP7)
ACAR104526849(DPP7)
CPEA104397877(DPP7)
AVIT104271162(DPP7)
CVF104291093(DPP7)
RTD128917356(DPP7)
CUCA104059114(DPP7)
TEO104379968
BRHI104492971(DPP7)
AAM106494235(DPP7)
AROW112969737(DPP7)
NPD112956119(DPP7)
TGT104573526(DPP7)
DNE112986764(DPP7)
SCAM104139733(DPP7)
ASN102372722(DPP7)
AMJ102571172(DPP7)
CPOO109313772(DPP7)
GGN109292849(DPP7)
PSS102456165(DPP7)
CMY102944633(DPP7)
CCAY125623276(DPP7)
DCC119844068(DPP7)
CPIC101946841(DPP7)
TST117889406(DPP7)
CABI116823286(DPP7)
MRV120386612(DPP7)
ACS100562590(dpp7)
ASAO132763598(DPP7)
PVT110078851(DPP7)
SUND121937295(DPP7)
PBI103050059(DPP7)
PMUR107295056(DPP7)
CTIG120308659(DPP7)
TSR106542599(DPP7)
PGUT117676553(DPP7)
APRI131186021(DPP7)
PTEX113443867(DPP7)
NSS113424258(DPP7)
VKO123028192(DPP7)
PMUA114589500(DPP7)
PRAF128406400(DPP7)
HCG128338838(DPP7)
GJA107123276(DPP7)
STOW125441877(DPP7)
EMC129342491(DPP7)
MUO115472701(DPP7)
DRE503737(dpp7)
SRX107709692
SANH107681243(dpp7) 107690688
SGH107560239
CCAR109099025
CAUA113049301(dpp7)
CGIB127957674
PTET122345542(dpp7)
LROH127165220(dpp7)
OMC131540667(dpp7)
PPRM120469502(dpp7)
RKG130089822(dpp7)
MAMB125266721(dpp7)
CIDE127512634
MASI127421085
TROS130568071(dpp7)
TDW130419198(dpp7)
MANU129440147(dpp7)
IPU108255762
IFU128625616(dpp7)
PHYP113536984(dpp7)
SMEO124380547(dpp7)
TFD113653305(dpp7)
TVC132854353(dpp7)
TRN134335515(dpp7)
AMEX103027831(dpp7)
CMAO118826959(dpp7)
EEE113577929(dpp7)
CHAR105889930(dpp7)
TRU101061692(dpp7)
TFS130525558(dpp7)
TNGGSTEN00004959G001
LCO104925283(dpp7)
NCC104966816(dpp7)
TBEN117472486(dpp7)
CGOB115014171(dpp7)
PGEO117451912(dpp7)
GACU117541202(dpp7)
EMAC134873497(dpp7)
ELY117253118(dpp7)
EFO125890960(dpp7)
PLEP121944093
SLUC116050669(dpp7)
ECRA117944691(dpp7)
ESP116686933(dpp7)
PFLV114555184(dpp7)
GAT120830401(dpp7)
PPUG119225046(dpp7)
AFB129101298(dpp7)
CLUM117736701(dpp7)
PSWI130196897(dpp7)
MSAM119892353(dpp7) 119917793
SCHU122875945(dpp7)
CUD121509537(dpp7)
ALAT119019036(dpp7)
MZE101469493(dpp7)
ONL100690872(dpp7)
OAU116311168(dpp7)
OLA101156583(dpp7)
OML112137702(dpp7)
CSAI133450809(dpp7)
XMA102233162(dpp7)
XCO114155126(dpp7)
XHE116729400(dpp7)
PRET103469621(dpp7)
PFOR103141938(dpp7)
PLAI106951547(dpp7)
PMEI106904615(dpp7)
PPRL129351625(dpp7)
CVG107088011(dpp7)
CTUL119789278(dpp7)
GMU124877757(dpp7)
KMR108245624(dpp7)
ALIM106528747(dpp7)
NWH119413691
AOCE111578428(dpp7)
MCEP125012079(dpp7)
CSEM103397365(dpp7)
POV109639094(dpp7)
HHIP117767913(dpp7)
HSP118114998(dpp7)
PPLT128439038(dpp7)
SMAU118313383(dpp7)
LCF108878395
SDU111226926(dpp7)
SLAL111647981(dpp7)
XGL120805355(dpp7)
HCQ109510557(dpp7)
PEE133400455(dpp7)
PTAO133473442(dpp7)
BPEC110154650(dpp7)
MALB109959747(dpp7)
BSPL114845430(dpp7)
SJO128364595(dpp7)
SASA106585425(dpp7)
STRU115164725(dpp7)
OTW112232798(dpp7)
OMY110525470(dpp7)
OGO124034455(dpp7)
ONE115111438(dpp7)
OKI109877685(dpp7)
OKE118393040(dpp7)
SALP111974867(dpp7)
SNH120058212(dpp7)
CCLU121584693(dpp7)
ELS105014134(dpp7)
SFM108938628(dpp7)
PKI111857532(dpp7)
AANG118237522(dpp7)
LOC102690439(dpp7)
PSPA121309602(dpp7)
ARUT117397025 117964682
PSEX120542394(dpp7)
LCM102363610(DPP7)
CMK103180401
RTP109927300
LERI129711931
PMRN116953141(DPP7)
LRJ133354589(DPP7)
BFO118410424 118420834
BBEL109469775 109484650
CIN100179268
SCLV120330153
SPU592836
LPIC129277712 129277715
APLC110981392 110981393 110981416 110989449
AJC117100014
SKO100367899 102804416
CSCU111618526
PTEP107437402
ABRU129969501
UDV129230484
SDM118192721
LPOL106477653
PMEO129599795
LGILOTGIDRAFT_235397
PVUL126820270 130010450
PCAN112575816
BGT106058014
GAE121383224 121392435
HRF124142808
HRJ124262957
CRG105320441
CVN111124640
CANU128192600
OED125679045
MYI110466518
PMAX117344579
MCAF127699850
MMER123550371
RPHI132747440
DPOL127837373
MAEA128224073
OBI106877801
OSN115222860
LJP135480210
LAK106179479
SMMSmp_071610
SHXMS3_00004349(DPP7)
EGLEGR_02544
NVE5500388 5520418
EPA110231171
ATEN116302681
ADF107327616 107347449
AMIL114956094
PDAM113673001 113673003
SPIS111340021
DGT114524658
XEN124445785 124445786
HMG100200663
HSY130636248
RES135684371
TADTRIADDRAFT_21030
TRETRIREDRAFT_108012
TRRM419DRAFT_5451
ACANACA1_116140
SMINv1.2.018349.t1(symbB.v1.2.018349.t1) v1.2.019631.t1(symbB.v1.2.019631.t1)
FCYFRACYDRAFT_247575
AAFAURANDRAFT_2013 AURANDRAFT_28266
EHXEMIHUDRAFT_204576 EMIHUDRAFT_241178
 » show all
Reference
1  [PMID:4969969]
  Authors
McDonald JK, Leibach FH, Grindeland RE, Ellis S.
  Title
Purification of  dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland. Peptidase and dipeptide esterase activities.
  Journal
J Biol Chem 243:4143-50 (1968)
Reference
2
  Authors
McDonald, J.K. and Schwabe, C.
  Title
Intracellular exopeptidases.
  Journal
In: Barrett, A.J. (Ed.), Proteinases in Mammalian Cells and Tissues, North-Holland Publishing Co., Amsterdam, 1977, p. 311-391.
Other DBs
ExplorEnz - The Enzyme Database: 3.4.14.2
IUBMB Enzyme Nomenclature: 3.4.14.2
ExPASy - ENZYME nomenclature database: 3.4.14.2
BRENDA, the Enzyme Database: 3.4.14.2
CAS: 76199-23-0

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