KEGG   ENZYME: 3.4.15.1
Entry
EC 3.4.15.1                 Enzyme                                 
Name
peptidyl-dipeptidase A;
dipeptidyl carboxypeptidase I;
peptidase P;
dipeptide hydrolase (ambiguous);
peptidyl dipeptidase;
angiotensin converting enzyme;
kininase II;
angiotensin I-converting enzyme;
carboxycathepsin;
dipeptidyl carboxypeptidase;
peptidyl dipeptidase I;
peptidyl-dipeptide hydrolase;
peptidyldipeptide hydrolase;
endothelial cell peptidyl dipeptidase;
ACE;
peptidyl dipeptidase-4;
PDH;
peptidyl dipeptide hydrolase;
DCP
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Peptidyl-dipeptidases
Reaction(IUBMB)
Release of a C-terminal dipeptide, oligopeptide!Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II
Comment
A Cl--dependent, zinc glycoprotein that is generally membrane-bound. A potent inhibitor is captopril. Important in elevation of blood pressure, through formation of angiotensin II (vasoconstrictor) and destruction of bradykinin (vasodilator). Two molecular forms exist in mammalian tissues, a widely-distributed somatic form of 150- to 180-kDa that contains two non-identical catalytic sites, and a testicular form of 90- to 100-kDa that contains only a single catalytic site. Type example of peptidase family M2
History
EC 3.4.15.1 created 1972, modified 1981, modified 1989, modified 1996, modified 2011
Orthology
K01283  peptidyl-dipeptidase A
Genes
HSA1636(ACE)
PTR107969298 449567(ACE)
PPS100980711(ACE) 100981368
GGO101139668 101145787
PON100453403(ACE) 100453767
NLE100592115 105737894
MCC100428661(ACE)
MCF102127700 102128376
CSAB103243232 103243233
CATY105590725(ACE)
PANU101020307
TGE112609814(ACE)
RRO104675473 104675505
RBB108536241 108536285
TFN117067444
PTEH111527592 111527614
CJC100408147(ACE)
SBQ101052117(ACE)
CSYR103265660
MMUR105861642(ACE) 105861733
LCAT123620584(ACE) 123621200
OGA100945027 100946178
MMU11421(Ace) 217246(Ace3)
MCAL110304805(Ace) 110305195
MPAH110331687(Ace) 110332456
RNO24310(Ace) 498012(Ace3)
MCOC116077933(Ace) 116078573
MUN110547034 110547055
CGE100753209(Ace3) 103158533(Ace)
MAUA101824864 101833239
PLEU114690399 114690491
MORG121436287 121436320(Ace)
AAMP119812098 119812858
NGI103744762 103744772
HGL101701835(Ace) 101703133
CPOC100712658 100714182 100715217(Ace) 100733866 100735910
CCAN109703262 109703285
DORD105998512(Ace) 105998551
DSP122103272 122103576
NCAR124980409 124980587
OCU100009274(ACE) 103351595
OPI101533604(ACE) 101534995
TUP102480658 102495265
CFA100856208 610668(ACE)
CLUD112652939 112653001
VVP112920644 112920698
VLG121473702 121474014
AML100463832 100464084
UMR103665896 103665897
UAH113265294(ACE) 113265295
UAR123803006 123803007
ELK111158152 111158167
LLV125086844 125086845
MPUF101676879 101677359 101677640(ACE)
ORO101377413 101382544
EJU114196714 114196729
ZCA113939154 113939873
MLX118024390 118024420
FCA101083124 101094061(ACE)
PYU121015249(ACE) 121015251
PBG122485753(ACE) 122485756
PTG102965986 102966279
PPAD109277113 109277114
AJU106978669 106978683
HHV120234177 120234183
BTA100295485(ACE3) 509484(ACE)
BOM102266786 102273543
BIU109573322 109574310
BBUB102392455 102395458
CHX102171917 106503207
OAS105613829 554335
ODA120866953 120866954
CCAD122433363 122439786
SSC100515049 613133(ACE)
CFR102505490 102514118
CBAI105069792 105069838 105069840
CDK105090416 105090499
VPC102532894
BACU103000257 103017916
LVE103087287
OOR101272368 101274195
DLE111182603(ACE)
PCAD102985025(ACE) 102985307
PSIU116745506(ACE)
ECB100064777 100064801(ACE)
EPZ103559240 103559241 103559246
EAI106835520 106835568
MYB102243978(ACE)
MYD102756093(ACE)
MMYO118671818(ACE)
MLF102417726(ACE)
MNA107531049(ACE)
PKL118726627
HAI109380275 109380308(ACE)
DRO112316275(ACE)
SHON119003488(ACE)
AJM119036302(ACE)
PDIC114502602(ACE)
PHAS123817563(ACE)
MMF118634520(ACE)
RFQ117012687 117012768(ACE)
PALE102880255 102890071(ACE)
PGIG120599965 120600373
PVP105297764 105297765
RAY107501813 107502259
MJV108400809 108401348
TOD119230616(ACE) 119232510
SARA101548258 101548526
LAV100661555 100667696
TMU101341729 101341987 101357365
DNM101413042 101420922
MDO100025797(ACE)
GAS123246196 123247930
SHR100932537 100932800
PCW110215741 110215742
OAA114815136(ACE)
GGA419953(ACE)
PCOC116233814(ACE)
MGP100542100(ACE)
CJO107325232(ACE)
NMEL110388589(ACE)
APLA101802065(ACE)
ACYG106045989(ACE)
AFUL116498500(ACE)
TGU100217841(ACE)
LSR110474830(ACE)
SCAN103821656(ACE)
PMOA120498197(ACE)
OTC121347708(ACE)
PRUF121352461(ACE)
GFR102032473(ACE)
FAB101819593(ACE)
PHI102111483(ACE)
PMAJ107215323(ACE)
CCAE111940103(ACE)
CCW104698643(ACE)
CBRC103619910(ACE)
ETL114066935(ACE)
ZAB102065179(ACE)
FPG101924109(ACE)
FCH102048145(ACE)
CLV102083877(ACE)
EGZ104134883(ACE)
NNI104009894(ACE)
PLET104618579(ACE)
PCRI104038703(ACE)
ACUN113489137(ACE)
TALA104369510(ACE)
PADL103913868(ACE)
ACHC115345056(ACE)
HALD104313802(ACE)
CCRI104157279(ACE)
CSTI104557834(ACE)
EHS104513983(ACE)
CMAC104476826(ACE)
FGA104076621(ACE)
GSTE104264711(ACE)
LDI104344268(ACE)
OHA104338713(ACE)
AAM106497416(ACE)
AROW112962781(ACE)
NPD112960180(ACE)
DNE112982806(ACE)
ASN102374457(ACE)
AMJ102573284(ACE)
CPOO109318963(ACE)
GGN109302091(ACE)
PSS102443828(ACE)
CMY102933955(ACE)
CPIC101930790(ACE)
TST117869220(ACE)
CABI116839490(ACE)
MRV120392083(ACE)
ACS100558092(ace)
PVT110080291(ACE)
SUND121935169(ACE)
PBI103067603(ACE)
PMUR107302404(ACE)
TSR106545809(ACE)
PGUT117664820(ACE)
VKO123031857(ACE)
PMUA114581443(ACE)
ZVI118095294(ACE)
GJA107125675(ACE)
STOW125444577(ACE)
XLA108701765
XTR100144634(ace)
NPR108785994(ACE)
RTEM120919027(ACE)
BGAR122941140(ACE)
DRE565980(ace)
SRX107708876(ace) 107743967
SANH107653924 107664635
SGH107557358(ace) 107598651
CCAR109060366(ace) 109099167
CAUA113056340 113111957
PPRM120474469(ace)
MAMB125255089(ace)
IPU108274082(ace)
PHYP113527416(ace)
SMEO124388635(ace)
TFD113653553(ace)
AMEX103040258(ace)
EEE113584762(ace)
TRU101076790(ace)
TNGGSTEN00024111G001
LCO104923252(ace)
NCC104966409(ace)
CGOB115024501(ace)
ELY117247632(ace)
EFO125881066(ace)
PLEP121959090
SLUC116044258(ace)
ECRA117936645(ace)
PFLV114547837(ace)
GAT120819300(ace)
PPUG119212747(ace)
MSAM119915522(ace)
CUD121528232(ace)
ALAT119009665(ace)
MZE101470840(ace)
ONL100712518(ace)
OAU116320154(ace)
OLA101172772(ace) 101173018 111946416
OML112154380 112154658(ace)
XMA102221242(ace) 102238075
XCO114151374(ace) 114151607
XHE116727094(ace) 116727735
PRET103481980(ace) 103482159
PFOR103142748 103143124(ace)
PLAI106958690(ace) 106964438
PMEI106904713 106923296
GAF122823727(ace)
CVG107100492(ace)
CTUL119792874(ace)
GMU124875539(ace)
NFU107373324 107374473 107374589 107388107(ace)
KMR108237275(ace)
ALIM106517337(ace) 106535188
NWH119423934(ace) 119424168 119424170 119424171
AOCE111570427(ace)
MCEP125022266(ace)
CSEM103382106(ace)
POV109626948(ace)
SSEN122759089(ace)
HHIP117752627(ace)
HSP118100408(ace)
LCF108875837(ace)
SDU111220374(ace)
SLAL111672022(ace)
XGL120794236(ace)
HCQ109515983(ace)
BPEC110159607(ace)
MALB109963664
BSPL114845366(ace)
SASA106578314 106579262
OTW112223647 112224096
OMY110491548 110498835
OGO124039909 124048311
ONE115106521 115143921
SALP111977173 111978277
SNH120045381 120060851
CCLU121547240 121567975
ELS105024522(ace)
SFM108928079(ace)
PKI111848632(ace)
AANG118217282 118221799
LOC102692099(ace)
PSPA121301717(ace)
ARUT117433335 117433482
LCM102356679 102358151
CMK103187713(ace)
RTP109937228
BFO118403150 118403314 118403321 118403506 118403507 118403682 118409681 118417365 118418232 118427679
BBEL109475027 109483872 109483913 109486676
CIN100177115 100180899
SCLV120342655 120343110
SPU100889485 574921 577312 578277 582767 593501 593516 593528
APLC110973283 110975980 110975981 110976389 110977723
SKO100369495 100371822 100373236 100375424
DMEDmel_CG10142(Ance-5) Dmel_CG10593(Acer) Dmel_CG16869(Ance-2) Dmel_CG17988(Ance-3) Dmel_CG8196(Ance-4) Dmel_CG8827(Ance)
DER6540862 6540890 6540915 6540929 6541763 6548439
DSE6608276 6611222 6611716 6618900
DSIDsimw501_GD10112(Dsim_GD10112) Dsimw501_GD23554(Dsim_GD23554) Dsimw501_GD23936(Dsim_Ance) Dsimw501_GD23937(Dsim_GD23937) Dsimw501_GD23939(Dsim_GD23939) Dsimw501_GD24910(Dsim_GD24910)
DYADyak_GE11404 Dyak_GE18694 Dyak_GE18695 Dyak_GE18785 Dyak_GE19012 Dyak_GE22653
DAN6494396 6495564 6497098 6498342
DSR110183874 110184068 110185592 110185727 110185942 110188985
DPO26533284 4803547 4804566 6902705 6902708 6902709 6903376 6903759 6904117
DPE113565405 113565453 6590076 6593017 6593982 6598001 6598003 6598005 6598006 6598008
DMN108158036 108158876 108161508 108162090 108163596 108163597 108163732 108163743 117187828 117190445
DWI26530341 6638145 6642187 6642191 6642421 6646754
DGR6559713 6560506 6561537 6561617 6562450 6562612
DMODmoj_GI10464 Dmoj_GI12636 Dmoj_GI12647 Dmoj_GI19428 Dmoj_GI19680
DAZ108609920 108611024 108611131 108616015 108616775
DNV108649360 108649398 108653177 108653430 115564748
DHE111597732 111600312 111600323 111603917 111604554
DVI6627173 6628146 6634022 6635836
CCAT101448622 101453723 101454020 101461472 101461648 101463032 101463213
BOD106621484 106621485 106623515 106623751 106624532 106625490 106625552
MDE101891220 101891395 101891581 101891754 101892102 101897093 101897276 101897451 101898307
SCAC106080891 106080905 106080907 106085079 106085086 106085098 106085099 106085974 106085977 106085978
LCQ111675739 111677496 111677497 111677526 111677527 111677534 111678184 111678189 111682932
LSQ119606338 119606339 119606341 119606342 119606343 119606347 119608604 119612463
AGAAgaP_AGAP004563(ANCE9) AgaP_AGAP007622(ANCE1) AgaP_AGAP007982(ANCE8) AgaP_AGAP009751(ANCE2) AgaP_AGAP009752(ANCE3) AgaP_AGAP009754(ANCE4) AgaP_AGAP009755(ANCE5) AgaP_AGAP009756(ANCE6) AgaP_AGAP009757(ANCE7)
ACOZ120953578 120955931 120955932 120955933 120955934 120956039 120956879 120959551 120959553 120961606
AARA120897794 120898219 120901409 120901935 120902104 120902105 120902106 120904353 120904355 120904356
ASTE118507469 118508806 118508810 118508811 118508812 118512071 118513872 118517090
AAG23687871 23687880 5564488 5571787 5571788 5575537 5576926
AALB109410834 109418632 109421171 109429410 109430368
CQUCpipJ_CPIJ004086 CpipJ_CPIJ008037 CpipJ_CPIJ009106 CpipJ_CPIJ009107 CpipJ_CPIJ009108 CpipJ_CPIJ016658
CPII120413133 120416008 120426646 120426647 120426648 120428353
CNS116339244 116341227 116343859 116350667
BCOO119066100 119073255 119076261 119076263 119076813
AME408536 726599
ACER107996204 107996328 108003297 108003669
ALAB122710834 122713950 122715300 122716150
BIM100741044 100741573 100741589 100746911
BBIF117206929 117212154 117214692 117216376
BVK117231635 117235883 117240133 117240379
BVAN117153818 117162749 117164332 117166272
BTER100643830 100648126 100648879
BPYO122566225 122567048 122574032 122575560
CCAL108630018 108630781
OBB114874107 114878974 114879032
MGEN117225107 117226508
NMEA116424047 116424874 116432458
CGIG122394838 122402087 122404689
SOC105194681 105205562 105205813 105205851
MPHA105832049 105836394 105838565 105838648
AEC105146699 105149150 105151359
ACEP105618474 105625639 105626741
PBAR105422935 105423690 105427913
VEM105559190 105560169 105564404 105565736
HST105187836 105188756 105190423 105191653
DQU106743048 106743873 106744872
CFO105255379 105255596 105258144 105258735
FEX115236437 115241566 115241625 115241911 115242370
LHU105675528 105676522 105677666 105677771
PGC109852369 109852448 109860351
OBO105277505 105281342 105282107 105285556
PCF106786393 106788340 106792150
PFUC122515598 122517743 122521062
VPS122635661 122637716 122637840
NVI100118011 100123549 100678623
CSOL105359611 105362386 105363868
TPRE106655001 106657748 106659265
MDL103572600 103576800 103578115
CGLO123263450 123264111 123265901 123268254
FAS105264884 105270777 105272583 105273275
DAM107036997 107040031 107040810 107041713 107043007
AGIF122848189 122850001 122852042 122855726
LHT122498256 122498617 122501603
CCIN107268193 107268194 107268195 107270864 107272995
TCA658047 658170(Ance-3) 658335 661107 663638
DPA109536526 109537454 109540808 109541221
SOY115879137 115879437 115881981 115889039
ATD109597090 109598516 109600257 109601515
CSET123307879 123308603 123315439 123315989 123323008
AGB108911069 108913027 108915521 108915563
LDC111502912 111506207
NVL108561359 108561583 108561585 108564313 108565889 108566579 108566581 108567239
APLN108738961 108741626 108742521
PPYR116158674 116158950 116163731 116163992 116177180 116178976 116179795 116181619
OTU111413086 111414514 111415386 111417926 111428233 111428427 111428456
BMOR101735566 101742492 101744965 101745756 692400
BMAN114241873 114245203 114245204 114245205 114246475 114247916 114252658
MSEX115439786 115441665 115444071 115446281 115446292 115446294 115450478
DPLKGM_205558 KGM_205559 KGM_205560 KGM_206216 KGM_210755
BANY112042963 112046929 112050032 112050069 112053787
PMAC106715187 106715578 106716199 106718138 106718792 106720249 106720307
PPOT106101419 106101799 106103673 106103675 106103677 106106263 106106309
PXU106115749 106115842 106115843 106122395 106122579 106123783 106123803
PRAP110993956 110996458 110996459 110996460 110997231 110998898 111001332
ZCE119836512 119836545 119837036 119837439 119840590
HAW110373323 110374317 110374326 110374328 110375642 110384674
HZE124631666 124631881 124631926 124643347
TNL113496423 113496652 113500811 113504235 113504281 113504317
SLIU111349922 111350104 111355492 111355493 111355494 111355961 111356205
OFU114351429 114352780 114355895 114357873 114361744 114365464 114365468 114366264
PXY105379965 105381320 105381904 105383330 105383331 105385122 105392336 105393255 105396664
API100164692 100166321 100166890 100168185(Ance-like) 100569104 100575164
DNX107162312 107162900 107163154 107169470
AGS114120823 114120839 114125644 114129465
RMD113551300 113552529 113554090 113558567
BTAB109031665 109037939 109037940 109042582
DCI103506926 103508843
CLEC106661523 106664466 106672168 106672985
HHAL106679626 106685585 106690221
NLU111044873 111050316 111055718 111059211 120352840
PHUPhum_PHUM034490 Phum_PHUM207460 Phum_PHUM522390 Phum_PHUM522500 Phum_PHUM522520
FOC113202759 113203185 113208755 113212059 113217743 113217744
TPAL117640983 117646256 117649397 117649398 117649875 117651373
ZNE110829908 110829909 110830098 110837138 110840923 110840973 110840990
CSEC111864141 111865324 111865329 111865333 111871771 111873661
FCD110842890 110845544 110851052 110852103 110856071 110858388
DPXDAPPUDRAFT_214350 DAPPUDRAFT_243454 DAPPUDRAFT_304127 DAPPUDRAFT_306022 DAPPUDRAFT_307230 DAPPUDRAFT_307838 DAPPUDRAFT_307858
DMK116922832 116923675 116923750 116923970 116926869 116929694
PVM113799967 113802353 113803188 113803786 113808966 113823712 113827588
PJA122246699 122249106 122254117 122259272 122264891
PCHN125035166 125035831 125039179 125041905
HAME121854067 121855324 121857197 121866016 121879054
PCLA123747242 123747373 123747374 123757374 123757692 123764501 123773274
PTRU123504193 123504222 123504280 123507320 123507408 123507448 123520204
HAZT108664804 108680274
EAF111695006 111695390 111697618
LSM121114739 121119666
PPOI119097286 119100896 119103205 119111444 119111448
ISCIscW_ISCW005573 IscW_ISCW010296 IscW_ISCW016487 IscW_ISCW016862
DSV119455430 119455496 119455499
RSAN119393732 119394328 119395013 119395038 119395040 119399541
RMP119172337 119172924 119179835
VDE111244364
VJA111271363
TUT107368139
DPTE113789144 113797912 113798300
DFR124490609 124493918
CSCU111612383 111622279 111622286 111625102 111641467
PTEP107441685 107444143 107445552 107445555 107448934
SDM118184501 118195242 118205234
CELCELE_C42D8.5(acn-1)
CBRCBG_14607(Cbr-acn-1)
BMYBM_BM2712(Bma-acn-1)
LOALOAG_08740
NAINECAME_01815
TSPTsp_01435
HROHELRODRAFT_111546 HELRODRAFT_191596 HELRODRAFT_76483 HELRODRAFT_98522
LGILOTGIDRAFT_115941 LOTGIDRAFT_118685 LOTGIDRAFT_161404 LOTGIDRAFT_215685 LOTGIDRAFT_215695
PCAN112557226 112557507 112573688
BGT106055618 106055619 106059089 106063041
GAE121371990
HRF124116121 124116125 124116126 124122559
HRJ124283354 124284705
CRG105325056 105337281(Ace) 117686524
MYI110442410 110457180 110457181 110457194
PMAX117320026
MMER123560737 123561361
OBI106868111 106869868
OSN115213195
LAK106150791 106161991 106171935
NVE116614488 5498715 5500329 5505310 5507095 5509484
EPA110236601 110246046 110246825
ATEN116295303 116302489 116307529
ADF107352074 107352075
AMIL114953923 114953924 114956778
PDAM113671633 113676309
SPIS111331992 111339682
DGT114523571 114536140 114536149 114536865
XEN124446807 124446969
HMG100202515 100206770 100210213
TADTRIADDRAFT_37492
XCCXCC1116
XCBXC_3130
XCAxcc-b100_3225
XCPXCR_1338
XCVXCV1249
XAXXACM_1192
XACXAC1217
XCIXCAW_03136
XCTJ151_01358
XCJJ158_01355
XCUJ159_01355
XCNJ169_01354
XCWJ162_01354
XCRJ163_01354
XCMJ164_01354
XCFJ172_01349
XFUXFF4834R_chr33230
XOMXOO3345(XOO3345)
XOOXOO3539
XOPPXO_04473
XOYAZ54_06030
XORXOC_1282
XOZBE73_16985
XALXALC_0887
XSASB85_07140
XTNFD63_04890
XVEBJD12_19380
XPEBJD13_10575
XHRXJ27_09090
XGABI317_07085
XVAC7V42_06590
XARXB05_00855
XHYFZ025_04405
XCZEBN15_04890
XTHG4Q83_00820
XEUXSP_001239
XHDLMG31886_31180
XPRMUG10_03740
SMLSmlt3574
SMTSmal_2996
BUJBurJV3_3026
SMZSMD_3147
SACZAOT14_25770
STEKAXG53_03980
SRHBAY15_2755
SLMBIZ42_04585
STENCCR98_15585
STEMCLM74_15910
STESMG068_15480
SINCDAIF1_31200
SPAQSTNY_R31680
PSUPsesu_2161
PSUWWQ53_02775
PSDDSC_06070
PMEXH4W19_00850
PJPLAG73_11460
PDDMNQ95_01770
LABLA76x_3622(ace)
LAQGLA29479_777
LCPLC55x_3591(ace)
LGULG3211_1594
LEZGLE_1570
LEMLEN_3391
LMBC9I47_2124
LYTDWG18_08965
LUEDCD74_05720
LYJFKV23_05785
LSOLGOY17_13295
LSXH8B22_11340
LAREHIV01_001405
LHXLYSHEL_03330
LCASLYSCAS_03330
LCICINQ41_10210
LAVIINQ42_09655
LLZLYB30171_01879
LUMCNR27_11825
LUGFPZ22_03155
THESFHQ07_04020
THEHG7079_10405
TCNH9L16_10100
TBVH9L17_04115
XBCELE36_13190
DKOI596_1523
XBAC7S18_07225
PAGRE2H98_02665
SONSO_2494
SDNSden_2117
SFRSfri_1887
SAZSama_1817
SBLSbal_2246 Sbal_4532
SBMShew185_2125
SBNSbal195_2170
SBPSbal223_2259
SBTSbal678_2173
SBSSbal117_2369
SBBSbal175_2295
SLOShew_2053
SSESsed_2057
SPLSpea_2340
SHEShewmr4_2051
SHMShewmr7_1924
SHNShewana3_2156
SWDSwoo_2544
SWPswp_2383
SVOSVI_2322
SHFCEQ32_05285
SJASJ2017_1962
SPSWSps_01127
SBJCF168_09980
SMAVCFF01_09060
SHEWCKQ84_19515
SLJEGC82_12125
SBKSHEWBE_2612
SKHSTH12_01499
SLITJQC75_09180
SPSHFM037_15145
SEURFM038_011230
SCYPJYB88_08570
SSEMJYB85_08750
SINVK8B83_11905
SXMMKD32_09470
CPSCPS_1585
COMCMT41_06100
COZA3Q34_17145
COLWA3Q33_14855
COLADBO93_12445
COVEKO29_06035
CBERB5D82_14950
LSDEMK97_00060
THTE2K93_01060
THABLP316_07465
PSEOOM33_11595
PPHEPP2015_1416
PRRAT705_01040
PLZS4054249_13475
PALNB0W48_14515
PPISB1L02_09310
PEAPESP_a1448
PSPOPSPO_a1844
PARTPARC_a2553
PTUPTUN_a1759
PSENPNC201_09645
PDJD0907_06655
PAGAPAGA_a2437
PCARPC2016_1992
PVBJ5X90_13405
PSAZPA25_13420
PDVFFU37_04500
PSYMJ1N51_01100
AMCMADE_1008755
AMAAamad1_09155
AMALI607_08070
AMAEI876_08335
AMAOI634_08440
AMADI636_08870
AMAII635_09140
AMAGI533_08380
AMACMASE_07965
AMBAMBAS45_08550
AMGAMEC673_08055
AMKAMBLS11_07960
ALTambt_09930
ASPAOR13_1841
ASQAVL57_07945
AAWAVL56_06825
ALEAV939_06955
ALZAV940_06800
GAGGlaag_2085
GNIGNIT_1032
PMESFX988_00392
LALAT746_11700
SALHHMF8227_01715
PAEWKIH87_07760
FESHER31_05360
CEGD0C16_22100
TTUTERTU_2099
SAGAM5M_17395
MTHDA3224_10760
MICCAUP74_01978
MAGAMag101_12285
MIIBTJ40_05910
MICTFIU95_05705
MHYDGTQ55_05640
MCELLPW13_03655
MICZGL2_26280
HJABST95_03020
LLOLLO_1982
LSHCAB17_11125
RHHE0Z06_04410
WOCBA177_18120
KKOKkor_1388
KGETQ33_1115
KSDKS2013_1165
KPDCW740_06445
SINIGT972_12445
FCEJN531_008905
RDPRD2015_4513
MNRACZ75_24275
MASWAM586_19455
MASYDPH57_25595
MASZC9I28_23710
MALIEYF70_03655
MUMFCL38_14990
MFLAGO485_10495
MPLIE1742_10800
DUGHH213_05255
UPVEJN92_15280
UPIEJG51_017610
ADEAdeh_2024
ACPA2cp1_1939
AFWAnae109_1785
ANKAnaeK_1854
MXAMXAN_3581
MSDMYSTI_04371
MYMA176_003327
MFBMFUL124B02_23325
CCXCOCOR_04454
MFULILAB_25885
MMASMYMAC_003522
SURSTAUR_4119
AGEAA314_05130
AVMJQX13_40170
MBDMEBOL_006925
CFUSCYFUS_004661
VINAKJ08_2640
SCLsce3979 sce5088
SCUSCE1572_23880 SCE1572_30910
CCROCMC5_062220
PAUUE8A73_002045 E8A73_002935
SAMYDB32_002593
LLUAKJ09_11323
MRMA7982_03788
HOHHoch_6422
MESPC1M53_16790
NOHG5V57_17615
PSFPSE_0360
CAKCaul_0184
CMBCSW64_01790
CAULKCG34_14895
PZUPHZ_c0316
BRDJL11_03565
BRGA4249_13230
BVCCEP68_07990
BREVE7T10_02090
BMEDGYM46_07230
BNDKWG56_14555
BGOEIFJ75_15565
BVITJIP62_11915
BALBM8231_13525
AEXAstex_0409
TSVDSM104635_02591
TMDKUV46_02265
MMRMmar10_1467
HYTHXX25_04825
HNEHNE_1947
HBAHbal_0598
CBOTATE48_16515
NPPPP1Y_AT21138
NPNJI59_18910
NREBES08_01765
NOVTQ38_007125
NORFA702_00395
NGFFRF71_10415
NOGGKE62_17420
NDRHT578_20545
SALSala_0456
SPHKSKP52_18105
SPHPLH20_16505
SMAGAN936_01840
SMAZLH19_18700
STERAOA14_08370
SGISGRAN_3476(ace)
SPHQBWQ93_13185
SPHOC3E99_12185
SPHXE5675_21165
SPHUSPPYR_0141
SWISwit_2667
SPHDHY78_12175
RDICMV14_02435
SPHMG432_00930
STAXMC45_04745
SPHITS85_09285
SSANNX02_12980
SNJA7E77_13945
SMYBJP26_07295
SPANAWL63_17445
SKRBRX40_16375
SPLMBXU08_02065
SPLKAV944_12650
SPKCKC8_02095
SPHCCVN68_01590
SPHFDM480_12300
SPHAD3Y57_06525
SPAUDRN02_005555
SLUTH9L13_07350
SRHIH9L12_04455
SLANGV829_11605
SSEDH9L14_06860
SPAPH3Z74_07680
SXAFMM02_01480
SPAIFPZ24_09425
SSING7078_07485
SSAUH8M03_01745
SARIH5J25_06730
SSUAFPZ54_01585
SBINSBA_ch1_24530
SAERNEF64_12015
SSYSLG_23650
SBDATN00_13785
SPHRBSY17_2968
SHYDCJD35_13065
SYAA6768_08710
SCLOSCLO_1007070
SPYGYGS_C1P1114
SAMISAMIE_1012830
SPPHKFK14_11620
CIJWG74_13430
SPHGAZE99_07535
SFLASPHFLASMR4Y_00851
SPHYCHN51_15470
SPHLLPB140_08200
BLASBSY18_285
BFWB5J99_10435
SPHJBSL82_07970
SPZRG5C33_09835
PALGHFP57_04005
PARJJ4G78_01540
PHAOHF685_02525
SMICSmB9_12650
SPHSETR14_20580
SANDH3309_06305 H3309_08985
AEPAMC99_01399
ALBAEB_P1567
ALHG6N82_14755
AAYWYH_00229
AMXAM2010_648
PMASNCF86_06735
ANHA6F65_01468
ADOA6F68_02380
TFVIDJ81_10300
EFVCHH26_07135
QCINCF85_07375
ELIELI_07405
ERKCD351_11280
ERRDVR09_10985
ERFFIU90_11345
EMVHQR01_10725
PNSA9D12_13260
PORLBG023_112159
PHZCHX26_12030
POTE2E27_10180
NCBC0V82_09325
ECOGFIV45_00315
TUMCBW65_02160
TABCIG75_04395
NTRB0W44_04260
KPULGXN76_05880
PABSJIR001_09640
AFTBBF96_12400
RXYRxyl_3178
RRDRradSPS_2735
RMARGBA65_00355
GVIgll3143
GLJGKIL_2224
GMLISF26_16250
CCZCCALI_02788
OBGVerru16b_00408
OLEK0B96_06360
PLHVT85_17175
GESVT84_35045
GOGC1280_16165
GMSSOIL9_09640
TIMGMBLW1_51560
LRSPX52LOC_01185
FTJFTUN_6918
ULIETAA1_12270
TSPHKIH39_12285
SACISinac_2369
PBORBSF38_03282
AGVOJF2_77400
UAMUABAM_06068
ABAAcid345_4468
TSAAciPR4_3174
TRSTerro_0304
TALBFTW19_25615
SUSAcid_4844
PFERIRI77_16265
ABACLuPra_00431
THYDTTHT_1108
SCORJ3U87_18375
GBAJ421_0092
BACCBRDCF_p1005
CBAECOR50_08685
RHOZGXP67_07405
HSWHsw_1814
HYMN008_16255
HYDPK28_11185
HYEAM218_05305
HYGAUC43_18185
HYPA0257_04740
HYHD3Y59_03365
HYJFHG12_17000
HBNGUY19_02110
HTSHMJ29_19055
HTBMTX78_12980
PKOPKOR_00660
PACTCA264_06060
ADDHUW48_10730
ASWUHUW51_18300
FBTD770_19145
FUVJR347_03315
FPALHYN49_09910
FMGHYN48_09400
LULLPB138_13980
FBUUJ101_00896(ACE)
OHOOweho_1053
CABYCabys_1631
 » show all
Reference
1  [PMID:2849100]
  Authors
Soubrier F, Alhenc-Gelas F, Hubert C, Allegrini J, John M, Tregear G, Corvol P
  Title
Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.
  Journal
Proc Natl Acad Sci U S A 85:9386-90 (1988)
DOI:10.1073/pnas.85.24.9386
  Sequence
[hsa:1636]
Reference
2  [PMID:2554286]
  Authors
Ehlers MR, Fox EA, Strydom DJ, Riordan JF.
  Title
Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme.
  Journal
Proc Natl Acad Sci U S A 86:7741-5 (1989)
DOI:10.1073/pnas.86.20.7741
  Sequence
[hsa:1636]
Reference
3  [PMID:1320019]
  Authors
Wei L, Clauser E, Alhenc-Gelas F, Corvol P
  Title
The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.
  Journal
J Biol Chem 267:13398-405 (1992)
Reference
4  [PMID:7674927]
  Authors
Corvol P, Williams TA, Soubrier F.
  Title
Peptidyl dipeptidase A: angiotensin I-converting enzyme.
  Journal
Methods Enzymol 248:283-305 (1995)
DOI:10.1016/0076-6879(95)48020-x
Other DBs
ExplorEnz - The Enzyme Database: 3.4.15.1
IUBMB Enzyme Nomenclature: 3.4.15.1
ExPASy - ENZYME nomenclature database: 3.4.15.1
BRENDA, the Enzyme Database: 3.4.15.1
CAS: 9015-82-1

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