KEGG   ENZYME: 3.4.16.6
Entry
EC 3.4.16.6                 Enzyme                                 
Name
carboxypeptidase D;
cereal serine carboxypeptidase II;
Saccharomyces cerevisiae KEX1 gene product;
carboxypeptidase Kex1;
gene KEX1 serine carboxypeptidase;
KEX1 carboxypeptidase;
KEX1 proteinase;
KEX1DELTAp;
CPDW-II;
serine carboxypeptidase (misleading);
Phaseolus proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine-type carboxypeptidases
Reaction(IUBMB)
Preferential release of a C-terminal arginine or lysine residue
Comment
A carboxypeptidase with optimum pH 4.5-6.0, inhibited by diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents (reviewed in [1]). In peptidase family S10 (carboxypeptidase C family).
History
EC 3.4.16.6 created 1972 as EC 3.4.12.1, transferred 1978 to EC 3.4.16.1, part transferred 1993 to EC 3.4.16.6 (EC 3.4.16.3 created 1972 as EC 3.4.12.12, transferred 1978 to EC 3.4.16.3, transferred 1992 to EC 3.4.16.1), (EC 3.4.21.13 created 1972, transferred 1978 to EC 3.4.16.1), modified 2011
Orthology
K01288  carboxypeptidase D
Genes
QSU111985319 112000736 112008046 112010307 112031355 112036920
SCEYGL203C(KEX1)
SEUBDI49_1775
SPAOSPAR_G00560
AGOAGOS_AFR549W
ERCEcym_1217
KLAKLLA0_F09999g
KMXKLMA_20260(KEX1)
LTHKLTH0G01980g
VPOKpol_1041p46
ZROZYRO0C06006g
CGRCAGL0G01232g
NCSNCAS_0E00660(NCAS0E00660)
NDINDAI_0I02850(NDAI0I02850)
TPFTPHA_0A05770(TPHA0A05770)
TBLTBLA_0I03220(TBLA0I03220)
TDLTDEL_0D05800(TDEL0D05800)
TGBHG536_0D05120
KAFKAFR_0D01410(KAFR0D01410)
KNGKNAG_0B00650(KNAG0B00650)
ZMKHG535_0B02420
PPAPAS_chr2-1_0174
DHADEHA2F22352g
PICPICST_78088(KEX1)
PGUPGUG_00385
SPAASPAPADRAFT_73535
LELLELG_05440
CALCAALFM_C700940WA(CaO19.7020)
CTPCTRG_04891
COTCORT_0G01740 CORT_0H00280
CDUCD36_70870
CTENCANTEDRAFT_119566
YLIYALI0B05170g
CLUCLUG_04442
CLUSA9F13_04g00627
CAURCJI97_003350
SLBAWJ20_993(KEX1)
PKZC5L36_0A07080
BNNFOA43_002128
BBRXBRETT_003872
OPAHPODL_04558
NCRNCU04316 NCU06720
NTENEUTE1DRAFT56417(NEUTE1DRAFT_56417) NEUTE1DRAFT57101(NEUTE1DRAFT_57101)
SMPSMAC_05571 SMAC_06613
PANPODANSg8857 PODANSg8931
TTTTHITE_121141 THITE_2108975
MTMMYCTH_2302321 MYCTH_2302738 MYCTH_97448
CTHRCTHT_0061740 CTHT_0063260
MGRMGG_00775
PPEIPpBr36_03117 PpBr36_08359
TMNUCRPA7_1896 UCRPA7_4147 UCRPA7_7378
SSCKSPSK_01057 SPSK_08740
FGRFGSG_04546 FGSG_05797 FGSG_10145
FPUFPSE_02639 FPSE_03226 FPSE_11231
FVRFVEG_02869 FVEG_04402 FVEG_11127
FOXFOXG_05262 FOXG_07474 FOXG_13694
NHENECHADRAFT_63845 NECHADRAFT_64790 NECHADRAFT_69476
TRETRIREDRAFT_66183 TRIREDRAFT_74517
TRRM419DRAFT_10901 M419DRAFT_25801
MAWMAC_01104 MAC_02763 MAC_03529 MAC_03847 MAC_04682 MAC_08114
MAJMAA_02240 MAA_02969 MAA_04542 MAA_05628 MAA_09950 MAA_10322
CMTCCM_01903 CCM_02046 CCM_05627
PLJVFPFJ_04784 VFPFJ_08558 VFPFJ_08594 VFPFJ_10515
VALVDBG_00507 VDBG_09155
VDAVDAG_00116 VDAG_07306
CFJCFIO01_02002 CFIO01_03220 CFIO01_03657 CFIO01_04609 CFIO01_09693
CHIGCH63R_03255 CH63R_06204 CH63R_08873 CH63R_13962
SAPOSAPIO_CDS2668 SAPIO_CDS5731
ELAUCREL1_8291 UCREL1_8304 UCREL1_8756
PFYPFICI_01738 PFICI_03315 PFICI_06116 PFICI_12307 PFICI_13115 PFICI_13795
SSLSS1G_05449 SS1G_09475 SS1G_10553 SS1G_13633
BFUBCIN_03g02030 BCIN_04g01480 BCIN_06g00630 BCIN_06g02510 BCIN_09g02350
MBEMBM_05049 MBM_07942 MBM_09227
PSCOLY89DRAFT_691164 LY89DRAFT_696238 LY89DRAFT_719400 LY89DRAFT_727454 LY89DRAFT_778734 LY89DRAFT_785996 LY89DRAFT_786346
GLZGLAREA_01023 GLAREA_09722 GLAREA_10188 GLAREA_11916
ANIAN1384.2 AN2555.2
AFMAFUA_1G08940 AFUA_2G03510 AFUA_6G00310
ACTACLA_026530 ACLA_091010 ACLA_099380
NFINFIA_016700 NFIA_035860
AORAO090005001632 AO090010000534 AO090020000351 AO090120000232
ANGANI_1_1212124(An14g02150) ANI_1_1592074(An08g00430) ANI_1_568044(An05g02170) ANI_1_664024(An02g04690) ANI_1_998064(An07g08030)
AFVAFLA_004461 AFLA_009455 AFLA_010311 AFLA_014021
ALUCAKAW2_11467S AKAW2_21223S AKAW2_30937S(KEX1) AKAW2_40904S AKAW2_81357S
ACHEACHE_30988S(KEX1)
APUUAPUU_50318A(KEX1) APUU_81007S
PCSPc16g01980 Pc18g04660 Pc20g10240 Pc22g21120
PDPPDIP_02600 PDIP_41670 PDIP_71590
TMFPMAA_007290 PMAA_021210 PMAA_045500
TRGTRUGW13939_04044 TRUGW13939_04059 TRUGW13939_10242
CIMCIMG_02284 CIMG_07181
CPWCPC735_035110 CPC735_039410
UREUREG_01452 UREG_05722 UREG_06786
PBLPAAG_00330 PAAG_06137
PBNPADG_02348 PADG_07980
ABEARB_01587 ARB_02032 ARB_03758 ARB_06414
TVETRV_01049 TRV_03565 TRV_05861 TRV_07747
AJEHCAG_01993
BGHBDBG_00152 BDBG_03944
PNOSNOG_05144 SNOG_14756 SNOG_14891
PTEPTT_00914 PTT_08433 PTT_18732
BZECOCCADRAFT_42167 COCCADRAFT_4776 COCCADRAFT_97830
BSCCOCSADRAFT_138953 COCSADRAFT_178202 COCSADRAFT_99447
BORCOCMIDRAFT_1823 COCMIDRAFT_27768 COCMIDRAFT_40804
AALTCC77DRAFT_1032844 CC77DRAFT_1064811 CC77DRAFT_930297
ZTRMYCGRDRAFT_106874 MYCGRDRAFT_109759 MYCGRDRAFT_42709 MYCGRDRAFT_75070(PEP-S10.1) MYCGRDRAFT_77233
PFJMYCFIDRAFT_162667 MYCFIDRAFT_37055 MYCFIDRAFT_58150 MYCFIDRAFT_60084 MYCFIDRAFT_63696
FFUCLAFUR5_05611 CLAFUR5_08887 CLAFUR5_09819 CLAFUR5_12123 CLAFUR5_13481
BCOMBAUCODRAFT_115526 BAUCODRAFT_87777
NPAUCRNP2_1073 UCRNP2_3893 UCRNP2_5314
TMLGSTUM_00004029001 GSTUM_00010123001
SPOSPAC1296.03c(sxa2) SPBC16G5.09
CNECNC05760 CND00600 CND01720 CNE00660
CNBCNBC1420 CNBD4620 CNBD5670 CNBE0600
CNGCNAG_00919 CNAG_01040 CNAG_02494 CNAG_02966
CGICGB_C8330W CGB_E0630W CGB_J2010C
TMSTREMEDRAFT_41638
TASAA1Q1_01088 A1Q1_05245 A1Q1_06751
PPLPOSPLDRAFT_88585
TVSTRAVEDRAFT_126828 TRAVEDRAFT_133452 TRAVEDRAFT_148659 TRAVEDRAFT_155002 TRAVEDRAFT_159926 TRAVEDRAFT_162948 TRAVEDRAFT_29080 TRAVEDRAFT_45058 TRAVEDRAFT_52610 TRAVEDRAFT_63629 TRAVEDRAFT_70376 TRAVEDRAFT_74788
DSQDICSQDRAFT_108110 DICSQDRAFT_110240 DICSQDRAFT_169358 DICSQDRAFT_181585 DICSQDRAFT_65706 DICSQDRAFT_99992
PCOPHACADRAFT_177131 PHACADRAFT_249107 PHACADRAFT_250924 PHACADRAFT_264079
SHSSTEHIDRAFT_147812 STEHIDRAFT_158272 STEHIDRAFT_169312 STEHIDRAFT_169473 STEHIDRAFT_49038 STEHIDRAFT_84379
HIRHETIRDRAFT_123766 HETIRDRAFT_146116 HETIRDRAFT_147022 HETIRDRAFT_437612 HETIRDRAFT_57243
PSQPUNSTDRAFT_105464 PUNSTDRAFT_128382 PUNSTDRAFT_133360 PUNSTDRAFT_136362 PUNSTDRAFT_142825 PUNSTDRAFT_147019 PUNSTDRAFT_77958
ADLAURDEDRAFT_115302 AURDEDRAFT_155239 AURDEDRAFT_162243 AURDEDRAFT_165386 AURDEDRAFT_165396 AURDEDRAFT_167524 AURDEDRAFT_168262 AURDEDRAFT_169176 AURDEDRAFT_170625 AURDEDRAFT_180086 AURDEDRAFT_184323 AURDEDRAFT_184759 AURDEDRAFT_50652 AURDEDRAFT_87806
FMEFOMMEDRAFT_100431 FOMMEDRAFT_115456 FOMMEDRAFT_116589 FOMMEDRAFT_135071 FOMMEDRAFT_87242 FOMMEDRAFT_90430
GTRGLOTRDRAFT_113875 GLOTRDRAFT_114370 GLOTRDRAFT_121369 GLOTRDRAFT_122955 GLOTRDRAFT_30246 GLOTRDRAFT_42128 GLOTRDRAFT_44561 GLOTRDRAFT_58449
LBCLACBIDRAFT_253991 LACBIDRAFT_292054
MPRMPER_06442
MRRMoror_1518 Moror_16893 Moror_17267 Moror_2050 Moror_2051
MOREE1B28_002557 E1B28_004799 E1B28_010066
CCICC1G_00916 CC1G_01392
SCMSCHCODRAFT_47644 SCHCODRAFT_48283 SCHCODRAFT_62395 SCHCODRAFT_77687
ABPAGABI1DRAFT37296(AGABI1DRAFT_37296) AGABI1DRAFT45474(AGABI1DRAFT_45474) AGABI1DRAFT70057(AGABI1DRAFT_70057) AGABI1DRAFT84490(AGABI1DRAFT_84490)
ABVAGABI2DRAFT195700(AGABI2DRAFT_195700) AGABI2DRAFT205752(AGABI2DRAFT_205752) AGABI2DRAFT68978(AGABI2DRAFT_68978) AGABI2DRAFT79914(AGABI2DRAFT_79914)
PCUBJR316_0004428 JR316_0005301
CPUTCONPUDRAFT_126951 CONPUDRAFT_130798 CONPUDRAFT_152664
SLASERLADRAFT_367312 SERLADRAFT_446295 SERLADRAFT_473031
WSEWALSEDRAFT_28238
WICJ056_001540
UMAUMAG_01888 UMAG_03465
PFPPFL1_02152 PFL1_06670
MGLMGL_0815 MGL_2498
MRTMRET_0003 MRET_4176
MSYMMSY001_0294 MSY001_2158 MSY001_2239
PGRPGTG_01128 PGTG_10662 PGTG_14112 PGTG_14427 PGTG_14432 PGTG_18559 PGTG_21811
MLRMELLADRAFT_116360 MELLADRAFT_117480 MELLADRAFT_123594 MELLADRAFT_123595
DDIDDB_G0280105
DFADFA_04033
PTIPHATRDRAFT_1391
FCYFRACYDRAFT_210750
TPSTHAPSDRAFT_261024 THAPSDRAFT_41521
AAFAURANDRAFT_2660
PIFPITG_02213
PSOJPHYSODRAFT_553288
SPARSPRG_00614
NGRNAEGRDRAFT_74700
 » show all
Reference
1
  Authors
Breddam, K.
  Title
Serine carboxypeptidases. A review.
  Journal
Carlsberg Res Commun 51:83-128 (1986)
Reference
2
  Authors
Breddam, K., Sorensen, S.B. and Svendsen, I.
  Title
Primary structure and enzymatic properties of carboxypeptidase II from wheat bran.
  Journal
Carlsberg Res Commun 52:297-311 (1987)
Reference
3  [PMID:3301004]
  Authors
Dmochowska A, Dignard D, Henning D, Thomas DY, Bussey H.
  Title
Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and alpha-factor precursor processing.
  Journal
Cell 50:573-84 (1987)
DOI:10.1016/0092-8674(87)90030-4
  Sequence
[sce:YGL203C]
Reference
4  [PMID:1390755]
  Authors
Liao DI, Breddam K, Sweet RM, Bullock T, Remington SJ.
  Title
Refined atomic model of wheat serine carboxypeptidase II at 2.2-A resolution.
  Journal
Biochemistry 31:9796-812 (1992)
DOI:10.1021/bi00155a037
Other DBs
ExplorEnz - The Enzyme Database: 3.4.16.6
IUBMB Enzyme Nomenclature: 3.4.16.6
ExPASy - ENZYME nomenclature database: 3.4.16.6
BRENDA, the Enzyme Database: 3.4.16.6
CAS: 153967-26-1

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