KEGG   ENZYME: 3.4.21.19
Entry
EC 3.4.21.19                Enzyme                                 

Name
glutamyl endopeptidase;
V8 proteinase;
endoproteinase Glu-C;
staphylococcal serine proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Preferential cleavage: Glu!, Asp!
Comment
From Staphylococcus aureus strain V8. In appropriate buffer the specificity is restricted to Glu!. In peptidase family S1 (trypsin family)
History
EC 3.4.21.19 created 1978
Orthology
K01318  glutamyl endopeptidase
Genes
LCP: LC55x_2678
LGU: LG3211_2491
LEM: LEN_4462
LMB: C9I47_2143
VGA: BSQ33_15410
VSR: Vspart_01428(mpr)
MII: BTJ40_14815
THIP: N838_17495
MCYS: MCB1EB_0941
MNR: ACZ75_25335
AOA: dqs_1446
RPC: RPC_3414
PLEO: OHA_1_01719(mpr)
SIL: SPO2645
SAL: Sala_1680
SSAN: NX02_00655
BMX: BMS_2026
BSR: I33_0263
BSL: A7A1_3257
BSH: BSU6051_02240(mpr)
BSUT: BSUB_00272(mpr)
BSUL: BSUA_00272(mpr)
BSUS: Q433_01385
BSO: BSNT_06531(mpr)
BSQ: B657_02240(mpr)
BSX: C663_0212(mpr)
BSS: BSUW23_01140(mpr)
BST: GYO_0423
BLI: BL01804(blaSE)
BLD: BLi00340(mpr)
BLH: BaLi_c03590(mpr)
BAQ: BACAU_0838(mpr)
BYA: BANAU_0781(mpr)
BAMP: B938_04160
BAML: BAM5036_0773(mpr)
BAMA: RBAU_0837(mpr)
BAMN: BASU_0813(mpr)
BAMB: BAPNAU_0794(mpr)
BAMT: AJ82_04810
BAMY: V529_08080(mpr)
BMP: NG74_00859(mpr)
BAO: BAMF_0814(mpr)
BAZ: BAMTA208_03925(mpr)
BQL: LL3_00873(mpr)
BQY: MUS_0875(mpr)
BAMI: KSO_015500
BAMC: U471_08510
BAMF: U722_04305
BCE: BC0789
BCA: BCE_0860
BTT: HD73_0905
BTHI: BTK_04505
BTI: BTG_17320
BTW: BF38_2029(mpr)
BMYC: DJ92_5771
BPU: BPUM_1681
BPUM: BW16_09265
BPUS: UP12_08655
BJS: MY9_0225
BACW: QR42_08595
BACP: SB24_05600
BACB: OY17_06960
BACY: QF06_00080
BACL: BS34A_02780(mpr)
BALM: BsLM_0229
BGY: BGLY_0338(blaSE)
GTN: GTNG_3484
SAU: SA0901(sspA) SA1627(splF)
SAV: SAV1048(sspA) SAV1809(splF) SAV1810(splD) SAV1813(splA) SAV2596
SAW: SAHV_1041(sspA) SAHV_1794(splF) SAHV_1795(splD) SAHV_1798(splA) SAHV_2580
SAM: MW0932(sspA) MW1752(splF) MW1755(splA)
SAR: SAR1022(sspA) SAR1902(splE) SAR1905
SAE: NWMN_0918(sspA) NWMN_1701(splF) NWMN_1702(splE) NWMN_1703(splD) NWMN_1706(splA)
SUE: SAOV_0994c SAOV_1795(splF)
SUW: SATW20_10450(sspA) SATW20_18060(splF) SATW20_18070(splE) SATW20_18080(splD) SATW20_18110(splA)
SUG: SAPIG1046
SAUS: SA40_0919(sspA) SA40_2350
SAUU: SA957_0934(sspA) SA957_2434
SAUG: SA268_0936(sspA) SA268_2532
SAUZ: SAZ172_0989(sspA) SAZ172_1824(splF) SAZ172_1827(splA)
SAB: SAB0915c(sspA) SAB1669c(splF) SAB1670c(splE)
SAUB: C248_1073(sspA)
SAUC: CA347_965(sspA)
SAUR: SABB_01014(sspA) SABB_01932(splF) SABB_01933(splE) SABB_01934(splD) SABB_01937(splA)
SER: SERP1397(sspA)
SEPP: SEB_01530
SEPS: DP17_458(gseA)
SHH: ShL2_00056(splE) ShL2_00097(splF)
SSP: SSP0282
SCA: SCA_2075
SDP: NCTC12225_00990(splB_1) NCTC12225_01668(splB_2)
SXO: SXYL_00314(sspA)
SHU: SHYC_05203(exhA)
SCAP: AYP1020_2166(splF)
SARL: SAP2_04080(gseA)
SPIC: SAMEA4384060_0473(splF)
SSIM: SAMEA4384339_0216(splF)
SSTE: SAMEA4384403_0924(sspA_1) SAMEA4384403_1136(sspA_2)
MCAK: MCCS_05630(sspA)
LMOD: LMON_0640
LMOM: IJ09_07155
LMOG: BN389_18960(blaSE)
LMP: MUO_09600
LMOX: AX24_07120
LMS: LMLG_0604
LMOK: CQ02_09705
LWE: lwe1890
LIV: LIV_1848
SNT: SPT_0436
SND: MYY_0470
SPNN: T308_01940
SNP: SPAP_0417
SPNE: SPN034156_14420(cbpG)
WCE: WS08_0604(gseA)
WCT: WS74_0605(gseA)
WCI: WS105_0602(gseA)
CTC: CTC_00612
ASF: SFBM_0615
ASM: MOUSESFB_0575(splA)
ASB: RATSFB_0509(splA)
BPRO: PMF13cell1_04548(bag_2)
MCHE: BB28_20115
MSTE: MSTE_04077(mpr)
MSAL: DSM43276_03714(mpr)
TPR: Tpau_4335
ARR: ARUE_c15360(blaSE)
AAU: AAur_1625
SERJ: SGUI_0506
MPH: MLP_03900
NML: Namu_1110
AMI: Amir_4522
ACTI: UA75_01145
ACAD: UA74_01145
AHG: AHOG_01110(blaSE1) AHOG_01120(blaSE2)
AEQ: AEQU_0663
STI: Sthe_3367
AHEL: Q31a_27220
PCAG: NCTC12856_01639(blaSE)
CPI: Cpin_3475
HSW: Hsw_2028
MOX: DAMO_1971
MHI: Mhar_0640
 » show all
Reference
1  [PMID:1012010]
  Authors
Drapeau GR.
  Title
Protease from Staphyloccus aureus.
  Journal
Methods Enzymol 45:469-75 (1976)
DOI:10.1016/S0076-6879(76)45041-3
Reference
2  [PMID:96922]
  Authors
Drapeau GR.
  Title
The primary structure of staphylococcal protease.
  Journal
Can J Biochem 56:534-44 (1978)
DOI:10.1139/o78-082
Reference
3  [PMID:3306605]
  Authors
Carmona C, Gray GL
  Title
Nucleotide sequence of the serine protease gene of Staphylococcus aureus, strain V8.
  Journal
Nucleic Acids Res 15:6757 (1987)
DOI:10.1093/nar/15.16.6757
  Sequence
[sau:SA0901]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.19
IUBMB Enzyme Nomenclature: 3.4.21.19
ExPASy - ENZYME nomenclature database: 3.4.21.19
BRENDA, the Enzyme Database: 3.4.21.19
CAS: 137010-42-5

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