KEGG   ENZYME: 3.4.21.2
Entry
EC 3.4.21.2                 Enzyme                                 
Name
chymotrypsin C
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Preferential cleavage: Leu!, Tyr!, Phe!, Met!, Trp!, Gln!, Asn!
Comment
Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family)
History
EC 3.4.21.2 created 1972
Orthology
K01311  chymotrypsin C
Genes
HSA11330(CTRC)
PTR739685(CTRC)
PPS100993635(CTRC)
GGO101129704(CTRC)
PON100431212(CTRC)
NLE100596494(CTRC)
MCC700270(CTRC)
MCF102128231 102135873
MTHB126959451 126959986
CSAB103225977(CTRC)
CATY105587355 105593653(CTRC) 105593656
PANU101008888 101027045 116271818
TGE112616893(CTRC)
RRO104667583(CTRC)
RBB108527935(CTRC)
TFN117093255(CTRC)
PTEH111528177(CTRC)
CJC100408655(CTRC)
SBQ101052168(CTRC)
CSYR103271168(CTRC)
MMUR105870484(CTRC)
LCAT123634886(CTRC)
OGA100958232(CTRC)
MMU76701(Ctrc)
MCAL110293441
MPAH110323568(Ctrc)
RNO362653(Ctrc)
MCOC116095650(Ctrc)
MUN110545284(Ctrc)
CGE100752962(Ctrc)
MAUA101832819(Ctrc)
PLEU114700843(Ctrc)
MORG121448515(Ctrc)
MFOT126509398
AAMP119817175(Ctrc)
NGI103725347(Ctrc)
HGL101703734(Ctrc)
CPOC100715802(Ctrc)
DORD105989966(Ctrc)
DSP122099151(Ctrc)
NCAR124966568
OCU100349800(CTRC)
OPI101532713(CTRC)
TUP102495129(CTRC)
CFA478220
CLUD112659989
VVP112929699
VLG121497973
AML100480752(CTRC)
UMR103666629
UAH113270477
UAR123777793
ELK111154872
LLV125098288
MPUF101682149
ORO101363399(CTRC)
EJU114213255
ZCA113927028
MLX118020332(CTRC)
NSU110574688
FCA101081235(CTRC)
PYU121021549
PBG122479962
LRUF124515873
PTG102964812(CTRC)
PPAD109274155
AJU106975574
HHV120229811
BTA514047(CTRC)
BOM102268940(CTRC)
BIU109570170(CTRC)
BBUB102412559(CTRC)
CHX102174957(CTRC)
OAS106991457(CTRC)
ODA120880581(CTRC)
CCAD122452439(CTRC)
SSC100520911(CTRC)
CFR102519329(CTRC)
CBAI105070947(CTRC)
CDK105107054(CTRC)
VPC102536763(CTRC)
BACU103001458(CTRC)
LVE103087747(CTRC)
OOR101271430(CTRC)
DLE111187165
PCAD102989176(CTRC)
PSIU116758491
ECB100054423(CTRC)
EPZ103565014(CTRC)
EAI106828009(CTRC)
MYB102250110(CTRC)
MYD102759310(CTRC)
MMYO118677092(CTRC)
MLF102427596(CTRC)
MNA107531552(CTRC)
PKL118724634(CTRC)
HAI109381248(CTRC)
DRO112298975(CTRC)
SHON118986321(CTRC)
AJM119049983(CTRC)
PDIC114496864(CTRC)
PHAS123831829(CTRC)
MMF118626830(CTRC)
RFQ117027361(CTRC)
PALE102878566(CTRC)
PGIG120585700(CTRC)
PVP105294414(CTRC)
RAY107501832(CTRC)
MJV108407502(CTRC)
TOD119236044(CTRC)
SARA101537271(CTRC)
LAV100657450(CTRC)
TMU101355357
DNM101433836(CTRC)
MDO100027379(CTRC)
GAS123243102(CTRC)
SHR100932004(CTRC)
PCW110197919(CTRC)
OAA100082025
GGA430670(CTRC)
PCOC116242491(CTRC)
MGP100550562(CTRC)
CJO107323260
NMEL110408511(CTRC)
APLA101795575(CTRC)
AFUL116497743(CTRC)
TGU105758763
LSR110472277
SCAN103824333(CTRC)
PMOA120498997 120499435
OTC121344016 121344148
PRUF121351341 121351382 121351397
GFR102039202 102039374 102039552
FAB101807907 101808103
PHI102104533
PMAJ107213488(CTRC)
CCAE111938464(CTRC)
CCW104697550
CBRC103623054
ETL114068723 114068724
ZAB102065082 102067097 102073038
ACHL103807211
FPG101922683(CTRC)
FCH102051553
CLV102088635(CTRC)
NNI104009093(CTRC)
TALA116960080(CTRC)
AFOR103907549
ACHC115342868(CTRC)
CSTI104556604
DPUB104305904(CTRC)
PGUU104463121
AROW112970066(CTRC)
NPD112959610
ASN102384487 102386144 102386393 102386635
AMJ102574442 102574676 102575846
CPOO109314379 109314516 109314543
GGN109293559 109293560 109293788 109293791
PSS102463762
CMY102940407
CPIC101932969(CTRC)
TST117868067
MRV120387758
PVT110072619
SUND121936187
PBI103063644(CTRC)
PMUR107291360(CTRC)
CTIG120319043(CTRC)
TSR106547431 106547433
PGUT117669676(CTRC)
VKO123034718
PMUA114602394
ZVI118079002 118079003 118086814 118087165
GJA107124381(CTRC)
STOW125445538(CTRC)
XLA443884(ctrc.L)
XTR493439(ctrc)
NPR108797194
RTEM120916258 120916260
BBUF120986271
SANH107668063
TRU101074028
LCO104920225
NCC104953342
MSAM119905643
PRET103467990
NFU107390706
CSEM103384948 107989142
LCF108891701
SDU111219121
SLAL111670777
XGL120804556
BPEC110168048(ctrc)
SALP111958114
ARUT117425043
DYADyak_GE27585
DGR6557889
DMODmoj_GI26169
AGAAgaP_AGAP003248 AgaP_AGAP005303 AgaP_AGAP005706 AgaP_AGAP013452
ACOZ120949877 120950135
AAG5577570
AALB109409749 109417827 109426733 109426788
CQUCpipJ_CPIJ002139 CpipJ_CPIJ011616
CPII120422905
BCOO119070589
CSOL105365739
TPRE106648766 106649093 106649500 106649502 106651994 106651995 111693485 111693486 111693565 111694337
TCA107397936
MSEX115454107
BANY112047013
SLIU111356397
AGS114128050 114131404
DMK116920723 116927092
LSM121120107
PPOI119096979
DSV119445572
RMP119164826
DPTE113799635
TSPTsp_12435
OSN115224217 115224509 115224512 115224554 115224560
NVE5520496
EPA110239935
ATEN116297736 116297737 116305518 116305520 116308478
AMIL114976376
PDAM113674894 113674914 113682978
HMG100213225
 » show all
Reference
1  [PMID:5792601]
  Authors
Peanasky RJ, Gratecos D, Baratti J, Rovery M.
  Title
Mode of activation of N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C.
  Journal
Biochim Biophys Acta 181:82-92 (1969)
DOI:10.1016/0005-2795(69)90229-3
Reference
2
  Authors
Folk, J.E.
  Title
Chymotrypsin C (porcine pancreas).
  Journal
Methods Enzymol 19:109-112 (1970)
Reference
3
  Authors
Wilcox, P.E.
  Title
Chymotrypsinogens - chymotrypsins.
  Journal
Methods Enzymol 19:64-108 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.2
IUBMB Enzyme Nomenclature: 3.4.21.2
ExPASy - ENZYME nomenclature database: 3.4.21.2
BRENDA, the Enzyme Database: 3.4.21.2
CAS: 9036-09-3

DBGET integrated database retrieval system