KEGG   ENZYME: 3.4.21.2
Entry
EC 3.4.21.2                 Enzyme                                 
Name
chymotrypsin C
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Preferential cleavage: Leu!, Tyr!, Phe!, Met!, Trp!, Gln!, Asn!
Comment
Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family)
History
EC 3.4.21.2 created 1972
Orthology
K01311  chymotrypsin C
Genes
HSA11330(CTRC)
PTR739685(CTRC)
PPS100993635(CTRC)
GGO101129704(CTRC)
PON100431212(CTRC)
NLE100596494(CTRC)
HMH116812955(CTRC)
MCC700270(CTRC)
MCF102128231 102135873
MTHB126959451 126959986
MNI105473247(CTRC)
CSAB103225977(CTRC)
CATY105587355 105593653(CTRC) 105593656
PANU101008888 101027045 116271818
TGE112616893(CTRC)
MLEU105529611(CTRC)
RRO104667583(CTRC)
RBB108527935(CTRC)
TFN117093255(CTRC)
PTEH111528177(CTRC)
CJC100408655(CTRC)
SBQ101052168(CTRC)
CIMI108286836(CTRC)
CSYR103271168(CTRC)
MMUR105870484(CTRC)
LCAT123634886(CTRC)
PCOQ105824903(CTRC)
OGA100958232(CTRC)
MMU76701(Ctrc)
MCAL110293441
MPAH110323568(Ctrc)
RNO362653(Ctrc)
MCOC116095650(Ctrc)
ANU117709185(Ctrc)
MUN110545284(Ctrc)
CGE100752962(Ctrc)
MAUA101832819(Ctrc)
PROB127213229(Ctrc)
PLEU114700843(Ctrc)
MORG121448515(Ctrc)
MFOT126509398
AAMP119817175(Ctrc)
NGI103725347(Ctrc)
HGL101703734(Ctrc)
CPOC100715802(Ctrc)
DORD105989966(Ctrc)
DSP122099151(Ctrc)
PLOP125354601(Ctrc)
NCAR124966568
MMMA107141589
OCU100349800
OPI101532713(CTRC)
TUP102495129(CTRC)
GVR103590596(CTRC)
CFA478220
CLUD112659989
VVP112929699
VLG121497973
NPO129513403
AML100480752(CTRC)
UMR103666629
UAH113270477
UAR123777793
ELK111154872
LLV125098288
MPUF101682149
MNP132000836
MLK131809426
NVS122898577
ORO101363399(CTRC)
EJU114213255
ZCA113927028
MLX118020332(CTRC)
NSU110574688
LWW102750665(CTRC)
FCA101081235(CTRC)
PYU121021549
PCOO112861733
PBG122479962
PVIV125172855
LRUF124515873
PTG102964812(CTRC)
PPAD109274155
PUC125913733
HHV120229811
BTA514047(CTRC)
BOM102268940(CTRC)
BIU109570170(CTRC)
BBUB102412559(CTRC)
BBIS104995967(CTRC)
CHX102174957(CTRC)
OAS106991457(CTRC)
BTAX128061242(CTRC)
ODA120880581(CTRC)
CCAD122452439(CTRC)
MBEZ129551376(CTRC)
SSC100520911(CTRC)
CFR102519329(CTRC)
CBAI105070947(CTRC)
CDK105107054(CTRC)
VPC102536763(CTRC)
BACU103001458(CTRC)
BMUS118902598(CTRC)
LVE103087747(CTRC)
OOR101271430
DLE111187165
PCAD102989176(CTRC)
PSIU116758491
NASI112402821(CTRC)
ECB100054423(CTRC)
EPZ103565014(CTRC)
EAI106828009(CTRC)
MYB102250110(CTRC)
MYD102759310(CTRC)
MMYO118677092(CTRC)
MLF102427596(CTRC)
PKL118724634(CTRC)
EFUS103292109(CTRC)
MNA107531552(CTRC)
DRO112298975(CTRC)
SHON118986321(CTRC)
AJM119049983(CTRC)
PDIC114496864(CTRC)
PHAS123831829(CTRC)
MMF118626830(CTRC)
PPAM129075636(CTRC)
HAI109381248(CTRC)
RFQ117027361(CTRC)
PALE102878566(CTRC)
PGIG120585700(CTRC)
PVP105294414(CTRC)
RAY107501832(CTRC)
MJV108407502
TOD119236044(CTRC)
SARA101537271(CTRC)
LAV100657450(CTRC)
TMU101355357
ETF101658572(CTRC)
DNM101433836(CTRC)
MDO100027379(CTRC)
GAS123243102(CTRC)
SHR100932004(CTRC)
AFZ127558167
PCW110197919(CTRC)
OAA100082025
GGA430670(CTRC)
PCOC116242491(CTRC)
MGP100550562(CTRC)
CJO107323260
TPAI128085093(CTRC)
LMUT125703491 125703494
NMEL110408511(CTRC)
APLA101795575(CTRC)
ACYG125183186(CTRC)
CATA118253241(CTRC)
AFUL116497743(CTRC)
TGU105758763
LSR110472277
SCAN103824333(CTRC)
PMOA120498997 120499435
OTC121344016 121344148
PRUF121351341 121351382 121351397
GFR102039202 102039374 102039552
FAB101807907 101808103
OMA130261778 130261779
PHI102104533
PMAJ107213488(CTRC)
CCAE111938464(CTRC)
CCW104697550
CBRC103623054
ETL114068723 114068724
ZAB102065082 102067097 102073038
ACHL103807211
SVG106856423 106856424
HRT120762265 120762439
FPG101922683(CTRC)
FCH102051553
CLV102088635(CTRC)
NNI104009093(CTRC)
TALA116960080(CTRC)
AFOR103907549
ACHC115342868(CTRC)
HLE104837866(CTRC)
AGEN126045323
CSTI104556604
SHAB115617334
DPUB104305904(CTRC)
PGUU104463121
RTD128918482(CTRC)
CUCA104060572(CTRC)
BRHI104502034
AROW112970066(CTRC)
NPD112959610
ASN102384487 102386144 102386393 102386635
AMJ102574442 102574676 102575846
CPOO109314379 109314516 109314543
GGN109293559 109293560 109293788 109293791
PSS102463762
CMY102940407
CCAY125624520
DCC119845040
CPIC101932969(CTRC)
TST117868067
MRV120387758
ASAO132764699(CTRC)
PVT110072619
SUND121936187
PBI103063644(CTRC)
PMUR107291360(CTRC)
CTIG120319043(CTRC)
TSR106547431 106547433
PGUT117669676(CTRC)
APRI131187005(CTRC)
PTEX113449770
NSS113423985
VKO123034718
PMUA114602394
PRAF128420408
ZVI118079002 118079003 118086814 118087165
HCG128338546
GJA107124381(CTRC)
STOW125445538(CTRC)
EMC129345051
XLA443884(ctrc.L)
XTR493439(ctrc)
NPR108797194
RTEM120916258 120916260
BBUF120986271
MUO115482668
GSH117349107(CTRC)
TRU101074028
LCO104920225
NCC104953342
MSAM119905643
PRET103467990
NFU107390706
CSEM103384948 107989142
LCF108891701
SDU111219121
SLAL111670777
XGL120804556
BPEC110168048(ctrc)
SALP111958114
ARUT117425043
PSEX120530891(ela2l)
LRJ133340727
DYADyak_GE27585
DGR6557889
DMODmoj_GI26169
CLON129610470
ACOZ120949877 120950135
AMER121591966
AFUN125771710
AAG5577570
AALB109409749 109417827 109426733 109426788
CQUCpipJ_CPIJ002139 CpipJ_CPIJ011616
CPII120422905
BCOO119070589
VCRB124422008
TPRE106649093 106649500 106649502 106651994 106651995 111693485 111693486 111693565 111694337
TCA107397936
BANY112047013
MJU123879036
VCD124539440 124539461
MCIX123664626
AGS114128050 114131404
IEL124154534 124173508
DMK116920723 116927092
LSM121120107
PPOI119096979
DSV119445572
RMP119164826
DPTE113799635
PMEO129586097
TSPTsp_12435
PVUL126832617
OSN115224509 115224512 115224554 115224560
NVE5520496
EPA110239935
ATEN116297736 116297737 116305518 116305520 116308478
AMIL114976376
PDAM113674894 113674914 113682978
HMG100213225
HSY130612517
 » show all
Reference
1  [PMID:5792601]
  Authors
Peanasky RJ, Gratecos D, Baratti J, Rovery M.
  Title
Mode of activation of N-terminal sequence of subunit II in bovine procarboxypeptidase A and of porcine chymotrypsinogen C.
  Journal
Biochim Biophys Acta 181:82-92 (1969)
DOI:10.1016/0005-2795(69)90229-3
Reference
2
  Authors
Folk, J.E.
  Title
Chymotrypsin C (porcine pancreas).
  Journal
Methods Enzymol 19:109-112 (1970)
Reference
3
  Authors
Wilcox, P.E.
  Title
Chymotrypsinogens - chymotrypsins.
  Journal
Methods Enzymol 19:64-108 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.2
IUBMB Enzyme Nomenclature: 3.4.21.2
ExPASy - ENZYME nomenclature database: 3.4.21.2
BRENDA, the Enzyme Database: 3.4.21.2
CAS: 9036-09-3

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