KEGG   ENZYME: 3.4.21.20
Entry
EC 3.4.21.20                Enzyme                                 

Name
cathepsin G;
chymotrypsin-like proteinase;
neutral proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Specificity similar to chymotrypsin C
Comment
From azurophil granules of polymorphonuclear leukocytes. In peptidase family S1 (trypsin family)
History
EC 3.4.21.20 created 1978
Orthology
K01319  cathepsin G
Genes
HSA: 1511(CTSG)
PTR: 467413(CTSG)
PPS: 100986490(CTSG)
PON: 100436066(CTSG)
NLE: 100591056(CTSG)
MCC: 716440(CTSG)
MCF: 102128983(CTSG)
CSAB: 103228742(CTSG)
RRO: 104662664(CTSG)
RBB: 108529494(CTSG)
CJC: 100400068(CTSG)
SBQ: 101051891(CTSG)
MMU: 13035(Ctsg)
MCAL: 110309192
MPAH: 110325404
RNO: 290257(Ctsg)
MUN: 110565885
CGE: 100767270
NGI: 103739491(Ctsg)
HGL: 101712232 101713070
CCAN: 109676125
TUP: 102471354(CTSG)
CFA: 106559147(CTSG)
VVP: 112926475
UMR: 103679302(CTSG)
UAH: 113246003(CTSG)
ORO: 101383583(CTSG)
ELK: 111162031
FCA: 101098719
PTG: 102957657(CTSG)
PPAD: 109254958
AJU: 106987851
BTA: 505658 509956
BOM: 102286039 102286316
BIU: 109575203 109575305
BBUB: 102397903 102398425
CHX: 102174648(CTSG) 102175113
OAS: 101121298 101121553
SSC: 100154047
CFR: 102517784 116664194
CDK: 105102447 105106639 116153491
BACU: 103009512(CTSG) 103010195
LVE: 103088005(CTSG) 103090225
OOR: 101287849(CTSG)
DLE: 111171097
PCAD: 102973677 102984870 112067657
ECB: 100053921
EPZ: 103561062(CTSG)
EAI: 106848617
MYB: 102253470 102253776
MYD: 102773521 102773806
MNA: 107544834 107544837 107545395
HAI: 109393625 109393630
PALE: 102887729 102891138
RAY: 107513514 107513515(CTSG)
MJV: 108392610
LAV: 100654642
TMU: 101352768 101353729
GGA: 426049(CTSG)
MGP: 100541485
CJO: 107325409
NMEL: 110388892
APLA: 101802752
ACYG: 106049561
TGU: 100225270
LSR: 110475735 110480577
SCAN: 103821693 103821694 103821935 103825764
GFR: 102043497
FAB: 101806847 101807047 101807227 101814633 107604218
PHI: 102102775 102112651
PMAJ: 107215203 107215418
CCAE: 111940154 111940383 111942839
CCW: 104696999 104697786
ETL: 114066403
FPG: 101923544
FCH: 102052223
CLV: 102084529 102092430
EGZ: 104124380
NNI: 104016273 104018468
ACUN: 113489366(GZMM)
PADL: 103917384 103923464
AAM: 106486400
ASN: 102371192 102372276 102374953 102386315(GZMM) 102386560 102388488 102388738 112548405
AMJ: 102561787 102562017 102567538(GZMM) 102570566(CTSG) 109283684
PSS: 102450564 102450790 102454962 102455240 102455738 102458929 102460838 102462227 102463428 106732597 112547215
CMY: 102932252 102935119 102936749 102938128 102946952
CPIC: 101931737 101932032 101935057 101936431 101943927 101945528 101946102 101946707 101946964 101947241 101947580 101952835 103306961
ACS: 100565934 103281292
PVT: 110079223 110079299
PBI: 103062353 103067502
TSR: 106541429
PMUA: 114588244 114588535 114588667 114588668 114588669 114588671 114588673 114588674
GJA: 107120589 107120597
XLA: 108696664 494802(gzmh.S)
XTR: 496758(gzmh)
NPR: 108791244
SANH: 107687736
SGH: 107554807
AMEX: 103040147
CVG: 107103712
NFU: 107375040
BPEC: 110174099
BMAN: 114246457
DPL: KGM_201312
PXY: 105384542
 » show all
Reference
1  [PMID:7341917]
  Authors
Barrett AJ.
  Title
Cathepsin G.
  Journal
Methods Enzymol 80 Pt C:561-5 (1981)
DOI:10.1016/s0076-6879(81)80044-4
Reference
2  [PMID:4016099]
  Authors
Tanaka T, Minematsu Y, Reilly CF, Travis J, Powers JC.
  Title
Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors.
  Journal
Biochemistry 24:2040-7 (1985)
DOI:10.1021/bi00329a036
Reference
3  [PMID:2569462]
  Authors
Hohn PA, Popescu NC, Hanson RD, Salvesen G, Ley TJ.
  Title
Genomic organization and chromosomal localization of the human cathepsin G gene.
  Journal
J Biol Chem 264:13412-9 (1989)
  Sequence
[hsa:1511]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.20
IUBMB Enzyme Nomenclature: 3.4.21.20
ExPASy - ENZYME nomenclature database: 3.4.21.20
BRENDA, the Enzyme Database: 3.4.21.20
CAS: 56645-49-9

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Gene (218)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (192)   
   RefGene (25)   
Protein sequence (28)   
   UniProt (6)   
   SWISS-PROT (3)   
   RefSeq(pep) (5)   
   PDBSTR (13)   
   PMD (1)   
DNA sequence (8)   
   RefSeq(nuc) (6)   
   GenBank (2)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   InterPro (6)   
All databases (265)   

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