Entry |
|
Name |
hypodermin C;
Hypoderma collagenase
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
|
Reaction(IUBMB) |
Hydrolysis of proteins including native collagen at !Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
|
Comment |
From the larva of a warble fly, Hypoderma lineatum. Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. In peptidase family S1 (trypsin family)
|
History |
EC 3.4.21.49 created 1981
|
Orthology |
|
Reference |
|
Authors |
Lecroisey A, Boulard C, Keil B. |
Title |
Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Lecroisey A, Keil B |
Title |
Specificity of the collagenase from the insect Hypoderma lineatum. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Lecroisey A, Gilles AM, De Wolf A, Keil B. |
Title |
Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum. |
Journal |
J Biol Chem 262:7546-51 (1987) |
Sequence |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 3.4.21.49 |
|