KEGG   ENZYME: 3.4.21.49Help
Entry
EC 3.4.21.49                Enzyme                                 

Name
hypodermin C;
Hypoderma collagenase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins including native collagen at !Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
Comment
From the larva of a warble fly, Hypoderma lineatum. Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. In peptidase family S1 (trypsin family)
History
EC 3.4.21.49 created 1981
Orthology
K20752  hypodermin C
Reference
1  [PMID:230030]
  Authors
Lecroisey A, Boulard C, Keil B.
  Title
Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum.
  Journal
Eur J Biochem 101:385-93 (1979)
DOI:10.1111/j.1432-1033.1979.tb19730.x
  Sequence
Reference
2  [PMID:2995028]
  Authors
Lecroisey A, Keil B.
  Title
Specificity of the collagenase from the insect Hypoderma lineatum.
  Journal
Eur J Biochem 152:123-30 (1985)
DOI:10.1111/j.1432-1033.1985.tb09171.x
  Sequence
Reference
3  [PMID:3034899]
  Authors
Lecroisey A, Gilles AM, De Wolf A, Keil B.
  Title
Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum.
  Journal
J Biol Chem 262:7546-51 (1987)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.49
IUBMB Enzyme Nomenclature: 3.4.21.49
ExPASy - ENZYME nomenclature database: 3.4.21.49
BRENDA, the Enzyme Database: 3.4.21.49
CAS: 122191-36-0

  All links  
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (4)   

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