KEGG ENZYME: 3.4.21.49

ENZYME: 3.4.21.49

Entry

EC 3.4.21.49                Enzyme

Name

hypodermin C;
Hypoderma collagenase

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases

Reaction(IUBMB)

Hydrolysis of proteins including native collagen at !Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment

Comment

From the larva of a warble fly, Hypoderma lineatum. Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. In peptidase family S1 (trypsin family)

History

EC 3.4.21.49 created 1981

Orthology

K20752

hypodermin C

Reference

1 [PMID:230030]

Authors

Lecroisey A, Boulard C, Keil B.

Title

Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum.

Journal

Eur J Biochem 101:385-93 (1979)
DOI:10.1111/j.1432-1033.1979.tb19730.x

Sequence

[ag:CAA52359]

Reference

2 [PMID:2995028]

Authors

Lecroisey A, Keil B

Title

Specificity of the collagenase from the insect Hypoderma lineatum.

Journal

Eur J Biochem 152:123-30 (1985)
DOI:10.1111/j.1432-1033.1985.tb09171.x

Sequence

[ag:CAA52359]

Reference

3 [PMID:3034899]

Authors

Lecroisey A, Gilles AM, De Wolf A, Keil B.

Title

Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum.

Journal

J Biol Chem 262:7546-51 (1987)

Sequence

[ag:CAA52359]

Other DBs

ExplorEnz - The Enzyme Database:

3.4.21.49

IUBMB Enzyme Nomenclature:

3.4.21.49

ExPASy - ENZYME nomenclature database:

3.4.21.49

BRENDA, the Enzyme Database:

3.4.21.49

CAS:	122191-36-0

All links

Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (7)   
   InterPro (7)   
All databases (9)   

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