KEGG   ENZYME: 3.4.21.54
Entry
EC 3.4.21.54                Enzyme                                 
Name
gamma-renin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Cleavage of the Leu!Leu bond in synthetic tetradecapeptide renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen, unlike renin (EC 3.4.23.15). Also hydrolyses Bz-Arg-p-nitroanilide
Comment
A member of the tissue kallikrein family, from submandibular glands of male mice. In peptidase family S1 (trypsin family)
History
EC 3.4.21.54 created 1986
Orthology
K01339  g-renin
Genes
MMU: 16615(Klk1b16)
Reference
1  [PMID:6337154]
  Authors
Poe M, Wu JK, Florance JR, Rodkey JA, Bennett CD, Hoogsteen K.
  Title
Purification and properties of renin and gamma-renin from the mouse submaxillary gland.
  Journal
J Biol Chem 258:2209-16 (1983)
  Sequence
[mmu:16615]
Reference
2  [PMID:3288617]
  Authors
Drinkwater CC, Evans BA, Richards RI
  Title
Sequence and expression of mouse gamma-renin.
  Journal
J Biol Chem 263:8565-8 (1988)
  Sequence
[mmu:16615]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.54
IUBMB Enzyme Nomenclature: 3.4.21.54
ExPASy - ENZYME nomenclature database: 3.4.21.54
BRENDA, the Enzyme Database: 3.4.21.54
CAS: 85270-20-8

  All links  
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
   PMD (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   InterPro (6)   
All databases (11)   

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