Entry |
|
Name |
venombin AB;
gabonase;
okinaxobin II;
Bitis gabonica venom serine proteinase;
afaacytin
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
|
Reaction(IUBMB) |
Selective cleavage at Arg! bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
|
Comment |
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin
|
History |
EC 3.4.21.55 created 1989
|
Reference |
|
Authors |
Pirkle H, Theodor I, Miyada D, Simmons G. |
Title |
Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties, and coagulant actions. |
Journal |
J Biol Chem 261:8830-5 (1986) |
Other DBs |
ExPASy - ENZYME nomenclature database: | 3.4.21.55 |
|