| Entry |
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| Name |
venombin AB;
gabonase;
okinaxobin II;
Bitis gabonica venom serine proteinase;
afaacytin
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
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| Reaction(IUBMB) |
Selective cleavage at Arg! bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
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| Comment |
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin
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| History |
EC 3.4.21.55 created 1989
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| Reference |
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| Authors |
Pirkle H, Theodor I, Miyada D, Simmons G. |
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| Title |
Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties, and coagulant actions. |
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| Journal |
J Biol Chem 261:8830-5 (1986) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.21.55 |
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