| Entry |
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| Name |
peptidase K;
Tritirachium alkaline proteinase;
Tritirachium album serine proteinase;
proteinase K;
Tritirachium album proteinase K;
endopeptidase K
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
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| Reaction(IUBMB) |
Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyses peptide amides
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| Comment |
From the mold Tritirachium album Limber. A peptidase of family S8 (subtilisin family) containing two disulfide bridges and one free Cys near the active site His. Formerly included in EC 3.4.21.14
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| History |
EC 3.4.21.64 created 1992 (EC 3.4.21.14 created 1961 as EC 3.4.4.16, transferred 1972 to EC 3.4.21.14, modified 1986, part incorporated 1992)
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| Reference |
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| Authors |
Ebeling W, Hennrich N, Klockow M, Metz H, Orth HD, Lang H. |
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| Title |
Proteinase K from Tritirachium album Limber. |
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| Journal |
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| Reference |
2 |
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| Authors |
Morihara, K. and Tsuzuki, H. |
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| Title |
Specificity of proteinase K from Tritirachium album Limber for synthetic peptides. |
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| Journal |
Agric Biol Chem 39:1489-1492 (1975) |
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| Reference |
|
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| Authors |
Kraus E, Kiltz HH, Femfert UF. |
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| Title |
The specificity of proteinase K against oxidized insulin B chain. |
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| Journal |
Hoppe Seylers Z Physiol Chem 357:233-7 (1976) |
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| Reference |
4 |
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| Authors |
Jany, K.-D., Lederer, G. and Mayer, B. |
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| Title |
Amino acid sequence of proteinase K from the mold Tritirachium album Limber. |
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| Journal |
FEBS Lett 199:139-144 (1986) |
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| Reference |
|
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| Authors |
Betzel C, Teplyakov AV, Harutyunyan EH, Saenger W, Wilson KS. |
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| Title |
Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.21.64 |
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