KEGG   ENZYME: 3.4.21.81
Entry
EC 3.4.21.81                Enzyme                                 
Name
streptogrisin B;
Streptomyces griseus protease B;
pronase B;
serine proteinase B;
Streptomyces griseus proteinase B;
Streptomyces griseus proteinase 1;
Streptomyces griseus serine proteinase B
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Hydrolysis of proteins with trypsin-like specificity
Comment
From Streptomyces griseus. A component of Pronase, in peptidase family S1 (trypsin family), distinct from Streptomyces trypsin
History
EC 3.4.21.81 created 1993
Orthology
K18545  streptogrisin B
Genes
SACAFFV09_05590
PFAEAJGP001_06280
MKMMkms_5532
MSPMspyr1_55270
MCBMycch_5478
MFXMFAL_21830
MAUBMAUB_00400
MPOFMPOR_54950
MABBMASS_2p0038
MIZBAB75_09800
CBQAL705_03275
SCOSCO1746(sal)
SALBXNR_5086
SMASAVERM_6552(sprA)
SGRSGR_5762(sprB)
SGBWQO_06490
SCBSCAB_72231(sprB)
SSXSACTE_1169
SVLStrvi_5376 Strvi_6818
SHYSHJG_3188
SHOSHJGH_2952
SRCM271_37665 M271_45515
SMALSMALA_0457 SMALA_1687
SSOII1A49_05805 I1A49_11575
SCTSCAT_0929(sprB)
SCYSCATT_09290
SFASfla_5084
SBHSBI_00863 SBI_01068 SBI_08266
SVESVEN_1360
SDVBN159_0673(sprB1) BN159_6809(sprB3) BN159_6810(sprB5)
SALSSLNWT_1594 SLNWT_6143
STRPF750_1587
SFISFUL_1286
SCIB446_09055
SALUDC74_2224
SALLSAZ_11790
SLVSLIV_29015(sprB)
SGUSGLAU_07695(sprB)
SVTSVTN_08255 SVTN_08260
STREGZL_06787
SCWTU94_07345
SLDT261_6435
SLCSL103_10580
SXISXIM_07460 SXIM_50000
STRMM444_09065
STRCAA958_04810 AA958_10100 AA958_25295 AA958_34010
SAMBSAM23877_1803(sprB)
SPRISPRI_5785 SPRI_5786 SPRI_6691
SCZABE83_29340
SCXAS200_34630
SRWTUE45_02212(sprB)
STRFASR50_08365
SLEsle_53830(sle_53830)
SPAVSpa2297_06855 Spa2297_29320
STRTA8713_06290
SCLFBB341_23215
SGSAVL59_35455
STSIA4E84_08770
SKYD0C37_27410
SALWCP975_07145
SGMGCM10017557_65270 GCM10017557_82300
SCADDN051_29890 DN051_35220
SLSSLINC_1992
SNRSNOUR_31630(sprB)
SPLULK06_005560 LK06_005565
STRDNI25_30485
SNWBBN63_01845 BBN63_03000 BBN63_27815
SAUOBV401_06045 BV401_11890
SSIAA7J05_28250
SVUB1H20_05690
SPUNBFF78_32705
SGVB1H19_10725
SLAUSLA_1275
SALFSMD44_01850 SMD44_06858
SALJSMD11_5272
SLXSLAV_28730(sprB)
STROSTRMOE7_09530
SFKKY5_1625c
SNZDC008_06860
SGEDWG14_06686(sprB_1) DWG14_07451(sprB_2)
SRJSRO_5731
SLKSLUN_08285
SDXC4B68_31810
SGDELQ87_30915
SCYAEJ357_04865 EJ357_09925
SASTCD934_13560 CD934_27000
SNQCP978_08275
STIRDDW44_07060
SKACP970_34545
SGZC0216_22020
SVNCP980_26080
SNKCP967_05440
SHAWCEB94_09200
SRKFGW37_07270
SFICEIZ62_26420
SGALCP966_07285
SSPODDQ41_05105
SPADDVK44_04750
SFYGFH48_31535
SAQUEJC51_08045 EJC51_11630
SGFHEP81_06036
SCAVCVT27_05325
SSEOD0Z67_05635
SBYH7H31_28615
SRIMCP984_32435
SSUBCP968_25880
SPHVF9278_08500
SCINCP977_07740
SFUGCNQ36_00910 CNQ36_07410
SPACB1H29_08030 B1H29_28820
STSUB7R87_29825
SCHACP983_01570 CP983_34135
SGXH4W23_08720
SCOECP976_09885
SBATG4Z16_17170 G4Z16_18325
SSPBCP982_10260 CP982_32580
SNFJYK04_02407(sprB)
SPLACP981_08645
SBROGQF42_11470
STUIGCM10017668_13330
SATAC5746_09470
SCHFIPT68_07895 IPT68_33135
SHUNDWB77_05984(sprB)
SHARHUT13_04295 HUT13_25285
SCYGS1361_09615(sprB)
SFEUIM697_13690
SLIAHA039_27255
SDWK7C20_08110
SVDCP969_09655
SCALI6J39_05865
SAUHSU9_006605
SMOBJ7W19_06580
SPRACP972_07765
SPEUCGZ69_07315
SROIIAG44_31700
SXNIAG42_00525 IAG42_28230
SGJIAG43_06160 IAG43_29335
SHKJ2N69_06980
SANUK7396_28130
SDDD9753_28080
SACTDMT42_07825 DMT42_07830
SMAOCAG99_02015 CAG99_23980
SGOBtest1122_01820
SINEKI385_03850 KI385_11185
SLFJEQ17_36405
SDECL3078_10025
SAOVG3H79_01340 G3H79_29835
KABB7C62_05440
CEZCBP52_16790
DCOSAMEA4475696_0499
NCQK6T13_16100
AGRAAGRA3207_001942 AGRA3207_005572
MICBMicB006_2395
MTUACSH63_05610 CSH63_08355
MICHFJK98_03920
MTEMGCE86_12520
MCABHXZ27_10275
MSAGGCM10017556_57180
ACTNL083_3867
ACTRAsp14428_68120
PLKCIK06_08870
ATLAthai_21160
CATICS0771_64130
DVCDvina_29680
GGRHKW67_21860
MBYMSBRM_0702
MBARMSBR2_1674
MMAZMmTuc01_1808
MHORMSHOH_3615
HBOHbor_38490
 » show all
Reference
1  [PMID:4899581]
  Authors
Jurasek L, Fackre D, Smillie LB.
  Title
Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus.
  Journal
Biochem Biophys Res Commun 37:99-105 (1969)
DOI:10.1016/0006-291X(69)90885-7
Reference
2  [PMID:6750612]
  Authors
Fujinaga M, Read RJ, Sielecki A, Ardelt W, Laskowski M Jr, James MN.
  Title
Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey.
  Journal
Proc Natl Acad Sci U S A 79:4868-72 (1982)
DOI:10.1073/pnas.79.16.4868
Reference
3  [PMID:6414511]
  Authors
Read RJ, Fujinaga M, Sielecki AR, James MN.
  Title
Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
  Journal
Biochemistry 22:4420-33 (1983)
DOI:10.1021/bi00288a012
Reference
4  [PMID:3112129]
  Authors
Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT
  Title
Characterization and structure of genes for proteases A and B from Streptomyces griseus.
  Journal
J Bacteriol 169:3778-84 (1987)
DOI:10.1128/JB.169.8.3778-3784.1987
  Sequence
[sgr:SGR_5762]
Reference
5  [PMID:2494344]
  Authors
Greenblatt HM, Ryan CA, James MN.
  Title
Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution.
  Journal
J Mol Biol 205:201-28 (1989)
DOI:10.1016/0022-2836(89)90376-8
  Sequence
[sgr:SGR_5762]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.81
IUBMB Enzyme Nomenclature: 3.4.21.81
ExPASy - ENZYME nomenclature database: 3.4.21.81
BRENDA, the Enzyme Database: 3.4.21.81
CAS: 55071-87-9

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