KEGG   ENZYME: 3.4.21.9Help
Entry
EC 3.4.21.9                 Enzyme                                 

Name
enteropeptidase;
enterokinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Activation of trypsinogen by selective cleavage of Lys6!Ile bond
Comment
Is not inhibited by protein inhibitors of trypsin. In peptidase family S1 (trypsin family).
History
EC 3.4.21.9 created 1961 as EC 3.4.4.8, transferred 1972 to EC 3.4.21.9
Orthology
K01316  enterokinase
Genes
HSA: 5651(TMPRSS15)
PTR: 458478(TMPRSS15)
PPS: 100992890(TMPRSS15)
GGO: 101151821(TMPRSS15)
PON: 100431479(TMPRSS15)
NLE: 100580929(TMPRSS15)
MCC: 100423099(TMPRSS15)
MCF: 102135270(TMPRSS15)
CSAB: 103218091(TMPRSS15)
RRO: 104673912(TMPRSS15)
RBB: 108543352(TMPRSS15)
CJC: 100401965(TMPRSS15)
SBQ: 101053552(TMPRSS15)
MMU: 19146(Tmprss15)
RNO: 288291(Tmprss15)
CGE: 100754500(Tmprss15)
NGI: 103732242(Tmprss15)
HGL: 101719326(Tmprss15)
CCAN: 109677737(Tmprss15)
OCU: 100350765(TMPRSS15)
TUP: 102474054(TMPRSS15)
CFA: 487700(TMPRSS15)
AML: 100477756(TMPRSS15)
UMR: 103673186(TMPRSS15)
ORO: 101363528(TMPRSS15)
FCA: 101088868(TMPRSS15)
PTG: 102969357(TMPRSS15)
AJU: 106973146(TMPRSS15)
BTA: 282009(TMPRSS15)
BOM: 102265063(TMPRSS15)
BIU: 109559391(TMPRSS15)
PHD: 102338924(TMPRSS15)
CHX: 102180152(TMPRSS15)
OAS: 101115497(TMPRSS15)
SSC: 397152(TMPRSS15)
CFR: 102520122(TMPRSS15)
CDK: 105086815(TMPRSS15)
BACU: 103001216(TMPRSS15)
LVE: 103081000(TMPRSS15)
OOR: 101289210(TMPRSS15)
ECB: 100067591(TMPRSS15)
EPZ: 103550998(TMPRSS15)
EAI: 106846583(TMPRSS15)
MYB: 102249267(TMPRSS15)
MYD: 102770624(TMPRSS15)
HAI: 109391711(TMPRSS15)
RSS: 109447502(TMPRSS15)
PALE: 102893141(TMPRSS15)
LAV: 100655543(TMPRSS15)
TMU: 101357439
MDO: 100020597(TMPRSS15)
SHR: 100928791(TMPRSS15)
OAA: 100079480(TMPRSS15)
GGA: 427967(TMPRSS15)
MGP: 100547096(TMPRSS15)
CJO: 107322530(TMPRSS15)
APLA: 101801915(TMPRSS15)
ACYG: 106036979(TMPRSS15)
TGU: 100220466(TMPRSS15)
GFR: 102042374(TMPRSS15)
FAB: 101817773(TMPRSS15)
PHI: 102106374(TMPRSS15)
PMAJ: 107212126(TMPRSS15)
CCAE: 111940884(TMPRSS15)
CCW: 104689447(TMPRSS15)
FPG: 101922858(TMPRSS15)
FCH: 102047221(TMPRSS15)
CLV: 102094803(TMPRSS15)
EGZ: 104128144(TMPRSS15)
AAM: 106494880(TMPRSS15)
ASN: 102380816(TMPRSS15)
AMJ: 102561133(TMPRSS15)
PSS: 102446226(TMPRSS15)
CMY: 102940846(TMPRSS15)
CPIC: 101946023(TMPRSS15)
ACS: 100554809(tmprss15)
PVT: 110074808(TMPRSS15)
PBI: 103048043(TMPRSS15)
GJA: 107113039(TMPRSS15)
XLA: 108709213
XTR: 100490249(tmprss15)
NPR: 108787208(TMPRSS15)
DRE: 100148042(tmprss15)
SRX: 107757854(tmprss15)
SANH: 107668446(tmprss15)
SGH: 107603215(tmprss15)
CCAR: 109050978(tmprss15)
IPU: 108262452 108278517
AMEX: 103039761(tmprss15)
TRU: 101079914(tmprss15)
TNG: GSTEN00014573G001
LCO: 104919454(tmprss15)
MZE: 101483978(tmprss15)
OLA: 100125450(tmprss15)
XMA: 102229238(tmprss15)
PRET: 103459937(tmprss15)
NFU: 107387187(tmprss15)
KMR: 108228482(tmprss15)
CSEM: 103395735(tmprss15)
LCF: 108873644(tmprss15)
SDU: 111239500(tmprss15)
HCQ: 109528878(tmprss15)
BPEC: 110174990(tmprss15)
MALB: 109955105(tmprss15)
SASA: 106603180(tmprss15)
OTW: 112228897(tmprss15)
ELS: 105027690(tmprss15)
SFM: 108923738(tmprss15)
LCM: 102345914(TMPRSS15)
CMK: 103189792(tmprss15)
BFO: BRAFLDRAFT_263105
APLC: 110983038
SKO: 100372484
DPX: DAPPUDRAFT_57647
TUT: 107366726
CRG: 105321499
MYI: 110457836
OBI: 106867184
ADF: 107329153 107340983 107345036 107358384
 » show all
Taxonomy
Reference
1  [PMID:2658218]
  Authors
Light A, Janska H.
  Title
Enterokinase (enteropeptidase): comparative aspects.
  Journal
Trends Biochem Sci 14:110-2 (1989)
DOI:10.1016/0968-0004(89)90133-3
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.9
IUBMB Enzyme Nomenclature: 3.4.21.9
ExPASy - ENZYME nomenclature database: 3.4.21.9
BRENDA, the Enzyme Database: 3.4.21.9
CAS: 9014-74-8

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Protein sequence (72)   
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3D Structure (2)   
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