KEGG ENZYME: 3.4.22.1

ENZYME: 3.4.22.1

Entry

EC 3.4.22.1                 Enzyme

Name

cathepsin B;
cathepsin B1 (obsolete);
cathepsin II

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases

Reaction(IUBMB)

Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg! bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides

Comment

An intracellular (lysosomal) enzyme in peptidase family C1 (papain family)

History

EC 3.4.22.1 created 1972

Orthology

K01363

cathepsin B

Genes

HSA:	1508(CTSB)

PTR:	463993(CTSB)

PPS:	100987583(CTSB)

GGO:	101152544(CTSB)

PON:	100173564(CTSB)

PPYG:

129042748(CTSB)

NLE:	100604807(CTSB)

HMH:	116473814(CTSB)

SSYN:

129487439(CTSB)

MCC:	100424758(CTSB)

MCF:	101865017(CTSB)

MTHB:

126961074

MNI:	105491189(CTSB)

CSAB:

103215319(CTSB)

CATY:

105579388(CTSB)

PANU:

101007225(CTSB)

TGE:	112629685(CTSB)

MLEU:

105532586(CTSB)

RRO:	104679114(CTSB)

RBB:	108536689(CTSB)

TFN:	117063489(CTSB)

PTEH:

111551353(CTSB)

CANG:

105512391(CTSB)

CJC:	100389833(CTSB)

SBQ:	101047879(CTSB)

CIMI:

108312520(CTSB)

ANAN:

105720712(CTSB)

CSYR:

103275039(CTSB)

MMUR:

105864815(CTSB)

LCAT:

123626546(CTSB)

PCOQ:

105811637(CTSB)

OGA:	100952002(CTSB)

MMU:	13030(Ctsb)

MCAL:

110309044(Ctsb)

MPAH:

110325177(Ctsb)

RNO:	64529(Ctsb)

MCOC:

116085396(Ctsb)

ANU:	117705316(Ctsb)

ASYL:

127691424(Ctsb)

MUN:	110541758(Ctsb)

CGE:	100756995(Ctsb)

MAUA:

101843949(Ctsb)

PROB:

127230272(Ctsb)

PLEU:

114693805 114703364

MORG:

121456455(Ctsb)

MFOT:

126507571

AAMP:

119799760(Ctsb)

NGI:	103729973(Ctsb)

HGL:	101709008(Ctsb)

CPOC:

100714169(Ctsb)

CCAN:

109682023(Ctsb)

DORD:

105991593(Ctsb)

DSP:	122125257(Ctsb)

PLOP:

125339475(Ctsb)

NCAR:

124982517

MMMA:

107153856(Ctsb)

OCU:

100101593

OPI:	101531489(CTSB)

TUP:	102483590(CTSB)

GVR:	103593365(CTSB)

CFA:	486077(CTSB)

CLUD:

112669644(CTSB)

VVP:	112926754(CTSB)

VLG:	121496786(CTSB)

NPO:	129523415(CTSB)

AML:	100476830(CTSB)

UMR:	103675931(CTSB)

UAH:	113269920(CTSB)

UAR:	123793572(CTSB)

ELK:

111154231

LLV:

125092926

MPUF:

101694438(CTSB)

MNP:	131999414(CTSB)

MLK:	131833738(CTSB)

NVS:	122889708(CTSB)

ORO:	101375531(CTSB)

EJU:	114217461(CTSB)

ZCA:	113924775(CTSB)

MLX:	118022144(CTSB)

NSU:	110588455(CTSB)

LWW:	102749422(CTSB)

FCA:	101084873(CTSB)

PYU:	121027009(CTSB)

PCOO:

112858176(CTSB)

PBG:	122474418(CTSB)

PVIV:

125163425(CTSB)

LRUF:

124520425

LGF:	123589883(CTSB)

AJU:

106975817

PTG:	102968829(CTSB)

PPAD:

109262395(CTSB)

PUC:

125923230

PLEZ:

122217689(CTSB)

HHV:	120222043(CTSB)

BTA:	281105(CTSB)

BOM:	102284921(CTSB)

BIU:	109562776(CTSB)

BBUB:

102410738(CTSB)

BBIS:

104988812(CTSB)

CHX:	102173295(CTSB)

OAS:	780470(CTSB)

BTAX:

128052199(CTSB)

CSUM:

138080858(CTSB)

ODA:	120857022(CTSB)

CCAD:

122452915(CTSB)

MREE:

136148431(CTSB)

OVR:	110127099(CTSB)

MBEZ:

129557483(CTSB)

SSC:	100037961(CTSB)

CFR:	102522938(CTSB)

CBAI:

105083368(CTSB)

CDK:	105101888(CTSB)

VPC:	102533649(CTSB)

BACU:

102999231(CTSB)

BMUS:

118897175(CTSB)

LVE:	103090468(CTSB)

OOR:	101283436(CTSB)

LALB:

132523916(CTSB)

DLE:	111185365(CTSB)

PCAD:

102983822(CTSB)

PSIU:

116754944(CTSB)

NASI:

112410693(CTSB)

ECB:	100060963(CTSB)

EPZ:	103558180(CTSB)

EAI:	106822582(CTSB)

MYB:	102240887(CTSB)

MYD:	102761828 102771390(CTSB)

MMYO:

118658185(CTSB)

MLF:	102423523(CTSB)

MDT:	132235362(CTSB)

MYUM:

139010696(CTSB)

PKL:	118711677(CTSB)

EFUS:

103294360(CTSB)

MNA:	107527504(CTSB)

DRO:	112312250(CTSB)

SHON:

118984315(CTSB)

AJM:	119039364 119049448(CTSB)

PDIC:

114503270(CTSB)

PHAS:

123814149(CTSB)

MMF:	118615564(CTSB)

PPAM:

129072553(CTSB)

HAI:	109379548(CTSB)

RFQ:	117037969(CTSB)

PALE:

102883622(CTSB)

PGIG:

120613356(CTSB)

PVP:	105291573(CTSB)

RAY:	107507224(CTSB)

MJV:	108402364(CTSB)

TOD:	119258045(CTSB)

SARA:

101538510 101551144(CTSB)

SFUM:

130023544(CTSB)

SETR:

126005821(CTSB)

LAV:	100663899(CTSB)

TMU:

101341172

ETF:	101644265(CTSB)

DNM:	101422184(CTSB)

MDO:	100032681(CTSB)

GAS:	123237006(CTSB)

SHR:	100920513(CTSB)

AFZ:	127543788 127548524

PCW:	110207612(CTSB)

TVP:	118843084(CTSB)

PBRV:

138176473(CTSB)

OAA:	100082449(CTSB)

TACU:

119949651(CTSB)

GGA:	396329(CTSB)

PCOC:

116235584(CTSB)

MGP:	100544902(CTSB)

CJO:	107312410(CTSB)

TPAI:

128085485(CTSB)

LMUT:

125689794(CTSB)

NMEL:

110395601(CTSB)

APLA:

101794268(CTSB)

ACYG:

106038130(CTSB)

CATA:

118256532(CTSB)

AFUL:

116487732(CTSB)

TGU:	100190482(CTSB)

LSR:	110481443(CTSB)

SCAN:

103821275(CTSB)

PMOA:

120496815(CTSB)

OTC:	121347450(CTSB)

PRUF:

121360759(CTSB)

ATRC:

139599888(CTSB)

GFR:	102045641(CTSB)

FAB:	101815778(CTSB)

OMA:	130250789(CTSB)

PHI:	102102206(CTSB)

PMAJ:

107202448(CTSB)

CCAE:

111927375(CTSB)

CCW:	104696872(CTSB)

CBRC:

103613270(CTSB)

ACOE:

138108752(CTSB)

ETL:	114069201(CTSB)

ZAB:	102068181(CTSB)

ZLE:	135446239(CTSB)

ACHL:

103807811(CTSB)

SVG:	106863201(CTSB)

MMEA:

130585632(CTSB)

HRT:	120750093(CTSB)

SATI:

136358686(CTSB)

CCIC:

134042375(CTSB)

FPG:	101920597(CTSB)

FCH:	102059814(CTSB)

CCRI:

104155295

NNT:	104412631(CTSB)

SHAB:

115610072(CTSB)

ACUN:

113478278(CTSB)

TALA:

104360542(CTSB)

ACHC:

115350923(CTSB)

HALD:

104322577(CTSB)

HLE:	104841448(CTSB)

AGEN:

126046594

HHAR:

128151720(CTSB)

GCL:

127014371

CSTI:

104557662(CTSB)

LDI:	104352393(CTSB)

MNB:	103778150(CTSB)

DPUB:

104306746(CTSB)

PPUS:

135177043(CTSB)

AVIT:

104270657(CTSB)

EGZ:	104127263(CTSB)

NNI:	104014687(CTSB)

PCRI:

104035361(CTSB)

PCAO:

104041315(CTSB)

PADL:

103913274(CTSB)

AFOR:

103906891(CTSB)

FGA:	104078893(CTSB)

GSTE:

104255092(CTSB)

CLV:	102084749(CTSB)

MUI:	104543324(CTSB)

PGUU:

104462003(CTSB)

PLET:

104614386(CTSB)

EHS:	104506676(CTSB)

CMAC:

104480635(CTSB)

CUCA:

104060730(CTSB)

TEO:	104380897(CTSB)

BREG:

104638925(CTSB)

OHA:	104336468(CTSB)

ACAR:

104524292(CTSB)

CPEA:

104392759(CTSB)

CVF:	104289047(CTSB)

RTD:	128906510(CTSB)

AAM:	106483924(CTSB)

AROW:

112963755(CTSB)

NPD:	112948531(CTSB)

TGT:	104565953(CTSB)

DNE:	112991183(CTSB)

SCAM:

104138987(CTSB)

ASN:	102378401(CTSB)

AMJ:	102573171(CTSB)

CPOO:

109312056(CTSB)

GGN:	109300254(CTSB)

PSS:	102453723(CTSB)

CMY:	102930234(CTSB)

CCAY:

125634703(CTSB)

DCC:	119853096(CTSB)

CPIC:

101943093(CTSB)

TST:	117875405(CTSB)

CABI:

116815292(CTSB)

MRV:	120401038(CTSB)

ACS:	100563878(ctsb)

ASAO:

132761610(CTSB)

PVT:	110070450(CTSB)

SUND:

121931257(CTSB)

PBI:	103051970(CTSB)

PMUR:

107289312(CTSB) 107301213

CTIG:

120318475(CTSB)

TSR:	106546573 106546575

PGUT:

117667728(CTSB)

APRI:

131189044(CTSB)

PTEX:

113446348(CTSB)

NSS:	113424355(CTSB)

VKO:	123033592(CTSB)

PMUA:

114594906(CTSB)

PRAF:

128411413(CTSB)

ZVI:	118082979(CTSB)

HCG:	128324175(CTSB) 128340069

GJA:	107112866(CTSB)

EMC:	129335352(CTSB)

XLA:	379257(ctsb.S) 380102(ctsb.L)

XTR:	394833(ctsb)

NPR:	108797919(CTSB)

RTEM:

120936191(CTSB)

BBUF:

120997204(CTSB)

BGAR:

122944557(CTSB)

PWL:	138296742(CTSB)

MUO:	115467054(CTSB)

GSH:	117356383(CTSB)

DRE:	406645(ctsba) 569298(ctsbb)

SRX:	107728112 107733172 107752788

SANH:

107661356 107674100(ctsb)

SGH:	107557005 107580233 107592770 107594835

CCAR:

109064698 109064705 109065792

CAUA:

113060627 113068580 113117245 113117368

CGIB:

127933310 127938601 127975912

PTET:

122324377(ctsbb) 122361777(ctsba)

LROH:

127179930(ctsba) 127182474(ctsbb)

OMC:	131522948(ctsba) 131527158(ctsbb)

PPRM:

120476842(ctsba) 120492022(ctsbb)

RKG:	130075742(ctsbb) 130100776(ctsba)

MAMB:

125269076(ctsba) 125278586(ctsbb)

CIDE:

127498308 127501960 127502348

CERY:

137006342(ctsba) 137018646(ctsbb)

MASI:

127410904 127416339 127455612

TROS:

130560616(ctsba) 130565554(ctsbb)

TDW:	130434089(ctsbb) 130437144(ctsba)

MANU:

129417486(ctsba) 129429229(ctsbb)

PDAB:

135737932(ctsbb) 135778041(ctsba)

IPU:	108269890(ctsba)

IFU:	128612852(ctsba)

PHYP:

113533939(ctsb)

SMEO:

124389827(ctsba)

TFD:	113651110(ctsba)

TVC:	132852874(ctsba)

CGAR:

128535684(ctsba)

NGRA:

132894144(ctsba)

TRN:	134325066(ctsba)

AMEX:

103032315(ctsbb) 103040417(ctsba)

CMAO:

118803181(ctsba) 118815880(ctsbb)

EEE:	113571882 113583676(ctsb)

CHAR:

122129464 122131160 122131929(ctsba)

SPIL:

134067647(ctsba) 134097316

TRU:	101070919 101076659

TFS:	130515979 130521903(ctsba)

TNG:	GSTEN00032819G001

LCO:	104920146 104921977

NCC:	104947341 104966683

TBEN:

117471404(ctsba) 117492239

CGOB:

115003533 115005227

PGEO:

117439472(ctsba)

GACU:

117533802 117551417(ctsba)

EMAC:

134863141(ctsba)

ELY:	117259888(ctsba) 117270782(ctsbb)

EFO:	125896924(ctsbb) 125903157(ctsba)

PLEP:

121950719(ctsba) 121955592

SLUC:

116060492(ctsba) 116066150

ECRA:

117959194(ctsba) 117961243

ESP:	116688443 116706388

PFLV:

114566738 114573278

GAT:	120807896 120831608(ctsba)

PPUG:

119194664 119224568(ctsba)

AFB:	129099445(ctsba) 129106843

CLUM:

117749121(ctsba)

PSWI:

130193169(ctsba) 130203011

CANA:

137794633(ctsba)

CVE:	137887489(ctsba)

MSAM:

119890479(ctsba)

SCHU:

122863530(ctsbb) 122868696(ctsba)

CUD:	121510725(ctsba) 121521491

SPUL:

138588859(ctsba)

LMIX:

132976717(ctsba)

ALAT:

119012156 119018398(ctsba)

ASTR:

137613694(ctsba)

MZE:	101475690 101480249 106676068

ONL:	100707845 109194844 109194845

OAU:	116310791 116310792 116313275(ctsba)

OLA:	101160638(ctsb) 101165526

OML:	112158204(ctsbb) 112160419(ctsba)

CSAI:

133418479 133463675(ctsba)

XMA:	102222087 102226401

XCO:	114143461 114158275

XHE:	116718743 116733744

PRET:

103457574(ctsb) 103462835

PFOR:

103136480 103138605

PLAI:

106941858 106957399

PMEI:

106906469 106928312

GAF:	122825042 122844711(ctsba)

PPRL:

129351186 129364094(ctsba)

CVG:	107083374(ctsb) 107092135

CTUL:

119785077 119789647(ctsba)

GMU:	124867606 124882363

NFU:	107377587(ctsb) 107381178

KMR:	108237382(ctsba) 108240069

ALIM:

106516844 106523671(ctsb)

NWH:	119418540 119430070(ctsba)

AOCE:

111589113

EJA:	138213238(ctsba)

BFRE:

138618172(ctsba)

MCEP:

124999414 125005924(ctsba)

CSEM:

103379409 103380823(ctsb)

POV:	109625184 109636207

SSEN:

122772216(ctsba) 122784255

HHIP:

117756532(ctsba) 117758411

HSP:	118099519(ctsbb) 118109995(ctsba)

PPLT:

128442963(ctsba) 128459937

SMAU:

118290087(ctsbb) 118302503(ctsba)

LCF:	108877023(ctsba) 108895657

SDU:	111219327 111239355

SLAL:

111653030 111668865

XGL:	120789083(ctsbb) 120796128(ctsba)

HCQ:	109528616(ctsb)

SSCV:

125967209(ctsba)

SBIA:

133498011(ctsba)

PEE:	133396833(ctsba)

PTAO:

133474315(ctsba)

BPEC:

110172821(ctsb)

MALB:

109953279 109954568(ctsb)

BSPL:

114849798 114852126(ctsba)

SJO:	128356817(ctsba) 128376995(ctsbb)

SSCO:

133982459(ctsba)

GMH:	115534018 115534020 115558277

SASA:

100195493(catb) 106607936(ctsb) 106611360(CATB)

STRU:

115161960 115172214 115190111

OTW:	112217696(ctsbb) 112260913(ctsba) 112261490

OMY:	100135964(ctsbb) 110497560 110505888

OGO:	123995189(ctsbb) 124001459 124046724(ctsba)

ONE:	115117358 115117380 115122135 115139312 115145893

OKI:	109866487 109894235 109904329

OKE:	118362819 118379777 118387010(ctsbb)

OMM:	135507861 135525538

SALP:

111963581 111968422 111972682(ctsb)

SNH:	120019037(ctsbb) 120023623 120060518

CCLU:

121539626 121544613 121566268

ELS:	105015425(ctsb)

SFM:	108921214 108923063 108924141(ctsb)

PKI:	111841289(ctsb) 111858275 111858279

AANG:

118230342(ctsba)

AROT:

135256960

CCOG:

133128135

LOC:	102698181(ctsb)

PSPA:

121315996(ctsbb)

ARUT:

117403126 117411196

PSEX:

120525837

LCM:	102351271(CTSB)

CMK:

103171629

RTP:

109925170

CPLA:

122552528

HOC:

132819288

LERI:

129699887

PMRN:

116957794(CTSB)

LRJ:	133340778 133344670

BFO:

118404562

BBEL:

109473040

CIN:

100176002

SCLV:

120339476

SPU:

582922

LPIC:

129263169

APLC:

110975330 110979509 110979580 110985061 110985066 110986094

ARUN:

117300760 117300770

AJC:

117124697

SKO:

100373078

PFLL:

139115838

DME:	Dmel_CG10992(CtsB)

DER:

6550867

DSE:

6618459

DSI:	Dsimw501_GD15875(Dsim_GD15875)

DYA:	Dyak_GE16138

DAN:

6505053

DSR:

110183232

DPO:

4815015

DPE:

6598439

DMN:

108164733

DWI:	6644385 6644681

DGR:

6569532

DMO:	Dmoj_GI15503

DAZ:

108619787

DNV:

108656605

DHE:

111603094

DVI:	6632024(CtsB)

CCAT:

101454096

BOD:

106614678

BDR:

105228237

RZE:	108374463 108375893 108378421

AOQ:

129237518

TDA:

119671847

MDE:

101887961

SCAC:

106091274

LCQ:

111690963

LSQ:	119610314 119614822

CVJ:	135956279(CtsB)

GFS:

119637393

ECOE:

129945513

CLON:

129618660

HIS:

119658512

AGA:	1274676 1274679 1274680

ACOZ:

120949785 120951099 120951100

AARA:

120894631 120900534 120900540

AMER:

121587685 121587686 121588528

ASTE:

118503033 118506149 118506150

AFUN:

125763882 125763883 125764396

AMOU:

128298844 128298845

AALI:

118468554 118468555 118468556

AAG:	5580008 5580010

AALB:

109411856 109412730 109412731 109413157 115259469 115259770 115259783

ASUA:

134203467 134203479 134214733 134214882 134214891 134214920 134214930

CQU:	CpipJ_CPIJ000566 CpipJ_CPIJ000574 CpipJ_CPIJ000575 CpipJ_CPIJ000577 CpipJ_CPIJ001239 CpipJ_CPIJ001240 CpipJ_CPIJ015761 CpipJ_CPIJ015762

CPII:

120415882 120416156 120416165 120416172 120416183 120416356 120416911 120419684 120419697 120419698 120421574 120421576 120421577 128092297

CNS:

116342434

BCOO:

119068310

LLL:

129790725

PPAP:

129807405

TCA:	655077 656957 657038 657117 657203 663066 663090 663117(GLEAN_02953) 663145

TMOL:

138122794 138122807 138128822 138128834 138137676 138137678 138137679 138137680 138137788 138137789 138137974 138137975 138138052 138138262 138138493 138138494 138138495 138138509 138138608 138138818 138138837 138138838 138138842 138138843 138138845 138138846 138138847 138138848 138138914 138139183 138139186 138139218 138139234 138139331

DPA:	109534389 109534403 109535944 109546849

ESIM:

136412669 136415497 136418149(CtsB) 136419177

EFOR:

136344628 136345024 136345766 136346158(CtsB)

SOY:	115875885 115875886 115876137 115881849 115882222 115886568 115886666 115891284

AGRG:

126733951 126747243

ATD:	109594218 109594220 109594225 109600684 126264976

CSET:

123313588 123313595 123313771

HAXR:

123673015

AGB:	108903776 108903839 108907040 108907042 108907044 108908125 108908268 108908272 108916593 108916595

LDC:	111505927 111505928 111505929 111505931 111505932 111505933 111506934 111506935 111506936 111511446 111513390 111513797 111515282

DVV:	114333388 114345135 126880412 126880413 126880415 126880416 126880417

NVL:

108557216

APLN:

108736788

PPYR:

116181007

OTU:

111424194

BMOR:

692390

BMAN:

114240639

MSEX:

115440409 115441274 115455971 115455975 115455983 119190012 119192554

DPL:	KGM_209245

BANY:

112048184

MJU:

123872019

NIQ:

126770592

VCD:

124529918

MCIX:

123657361

PMAC:

106710142

PPOT:

106107413

PXU:	106116636 106118961

BPHI:

137920479 137932083(CtsB)

PRAP:

111001540

PBX:

123708335

PNAP:

125049400 125049581

ZCE:	119829006 119829133 119829134 119829135 119832264

CCRC:

123695301

LSIN:

126979235

AAGE:

121732256

HAW:	110376576 110376695 110376862 126055237 126055238

HZE:	124633202 124633205 124633245 124633331 124633332

TNL:	113491926 113491927 113499462

SLIU:

111349024 111359566 111359583

OFU:	114351036 114362629

ATRA:

106141851 106141860 106142526

GMW:	113510551 113515111

PXY:

105390633

PGW:	126368737 126368738 126377167 126377168 126377169 126377170

LGLY:

125229605 125233099 125233396 125234453 125234454 125234455

CSTB:

134743942 134744061 134756093

CFEL:

113368019

CCRN:

123298943 123298944 123299063

API:

100144775(Catb-348) 100144778(Catb-1852) 100144780(Catb-912) 100144781(Catb-2744) 100144782(Catb-1418) 100144784(Catb-1674) 100144785(Catb-16a) 100144787(Catb-84) 100144788(Catb-5880) 100144790(Catb-3098) 100144791(Catb-16d2) 100144792 100144794(Catb-1874) 100144795(Catb-3483) 100144796(Catb-10270) 100159094 100159833 100159850 100159943 100160743 100161139 100162979 100164098 100164982 100169466 103307611

DNX:	107163067 107163300 107163302 107167171 107167173 107167174 107169601 107169755 107170467 107170713 107171777 107173550

AGS:	114118922 114121295 114121837 114122234 114124769 114126896 114126988 114127871 114127875 114129224 114129225 114129229 114129231 114130415 114130418 114130419

RMD:	113549020 113551310 113555206 113555454 113555465 113556418 113557036 113557573 113558910 113559015 113559198 113559255 113559345 113559406 113559439 113559456 113560849

ACOO:

126833763 126835430 126835565 126835570 126835572 126836109 126836181 126836182 126836954 126837016 126837070 126837071 126837073 126837074 126837075 126837076 126837867 126841889 126842805 126844065 126844144 126844146 126844147 126844148 126844149 126844150 126844151 126844160 126844492 126844816 126844965 126844966 126845377 126847533

DVT:	126896435 126897367 126898178 126898195 126899574 126899669 126899820 126899983 126899984 126899985 126899986 126899987 126902487 126907450 126909067

BTAB:

109029571 109031298 109031448 109031579 109031589 109031686 109031695 109031711 109031716 109031725 109031785 109031789 109032115 109032131 109032359 109032360 109032723 109032724 109033117 109033119 109033348 109033349 109033623 109033651 109037205 109037265 109037266 109037267 109037764 109037765 109038988 109039003 109039352 109039906 109040144 109040200 109040558 109040585 109041945 109042262 109042326 109042327 109042343 109042350 109042351 109042507 109042510 109044371

DCI:	103505051 103508275 103508281 103511936 103512056 103512321 103513554 103524128 113471629

CLEC:

106663793 106663804 106663871 106663936 106663944 106664002

HHAL:

106685198 106689147 106689154 106689155 106690036(CtsB)

NLU:	111045008 111045013 111045014 111048658 111054587 111056618

HVI:	124358926 124359354 124359355 124359575 124370911 124372836

MQU:	128987106 128993391 128999656 129000741

FOC:	113203141 113214018

TPAL:

117640115 117640116 117644800 117651121

ZNE:

110830373

CSEC:

111870295

SGRE:

126346021

BROR:

134528498

IEL:	124160728 124160731

FCD:	110853490 110859204 110859213 110860420 110862120

DPX:	DAPPUDRAFT_306608 DAPPUDRAFT_308155 DAPPUDRAFT_340646

DMK:	116923628 116930399

DPZ:	124340532 124341998

AFRA:

136035198

PVM:

113808173

PJA:

122259857

PMOO:

119594118 119594286

HAME:

121857098

PCLA:

123768225(CtsB)

CQD:	128700704(CtsB)

PTRU:

123509185

ESN:

126992711

MNZ:	135207547 135207559 135207560

MRJ:	136845835 136845840 136850810 136850826 136850827 136850829

PORN:

139750982(CtsB)

HAZT:

108668260 108668261 108673649 108677150 108680231 108680239

EAF:

111704308

LSM:	121121107 121127728

TCF:

131884139

DSV:	119440535 119441980 119442701 119456288 119456979 119456980

RSAN:

119386401 119387479 119387889 119388404 119388405

RMP:	119159747 119184559 119188261

TUT:	107359293 107359924 107360115 107361025 107361476 107362279 107362325 107362596 107362934 107362935 107367797 107367992 107368756 107368832 107368859 107369972 107370473 107371482 107372160 107372161 107372162 112538523

DPTE:

113796500 113796509

DFR:	124498425 124498817 124498819 124498820

CSCU:

111615854 111633346 111633349 111639363 111639371

CVS:	136988801 136989026

PTEP:

107439411 122272375

UDV:	129228071 129228175

SDM:

118205112

LPOL:

106457072

PMEO:

129583280 129590341 129592695 129595536 129595537 129595585 129596291 129597900 129597904 129600113 129601145

CEL:	CELE_C25B8.3(cpr-6) CELE_C52E4.1(cpr-1) CELE_F32H5.1(F32H5.1) CELE_F36D3.9(cpr-2) CELE_F44C4.3(cpr-4) CELE_F57F5.1(cpr-9) CELE_T10H4.12(cpr-3) CELE_W07B8.1(cpr-8) CELE_W07B8.4(W07B8.4) CELE_W07B8.5(cpr-5)

CBR:	CBG_01102 CBG_01103(Cbr-cpr-5) CBG_01104 CBG_06539 CBG_06540 CBG_06541 CBG_10849(Cbr-cpr-6) CBG_17499 CBG_17826 CBG_17829 CBG_18635(Cbr-cpr-3) CBG_18654 CBG_18657 CBG_18978(Cbr-cpr-4) CBG_22436 CBG_23343(Cbr-cpr-1) CBG_23351 CBG_24861

CRQ:	GCK72_017963 GCK72_018151 GCK72_018160 GCK72_018553 GCK72_019654 GCK72_019793 GCK72_020863 GCK72_020864 GCK72_020866 GCK72_024615

NAI:	NECAME_01684 NECAME_02725 NECAME_02726 NECAME_02743 NECAME_02744 NECAME_03383 NECAME_04857 NECAME_06064 NECAME_12453 NECAME_12455 NECAME_14048 NECAME_14336

BMY:	BM_BM2365(Bma-cpr-6) BM_BM951(Bm951)

LOA:	LOAG_15077 LOAG_17287

TSP:	Tsp_00611 Tsp_01277 Tsp_01409 Tsp_01410 Tsp_03306 Tsp_07747

HRO:	HELRODRAFT_186015

LGI:	LOTGIDRAFT_197490

PVUL:

126824820

PCAN:

112561908 112562422 112562423

LSAX:

138979384

BGT:	106052689 106062216

GAE:

121377457

HRF:	124131581 124131582

HRJ:	124291313 124291314

HASI:

137278539 137278540

HCRA:

139461706 139474376

CRG:

105328916

CANU:

128179648

CVN:

111111564

OED:

125646282

MYI:	110465747 110465802

PMAX:

117316151 117316413 117321043

AIRR:

138308956 138309528

MCAF:

127726045

MMER:

123540194

RPHI:

132729818

DPOL:

127864508 127865684

MAEA:

128205708 128206494

OBI:

106873643

OSN:

115210644

LJP:

135463596

LAK:

106173360

SMM:	Smp_067060 Smp_085010 Smp_085180 Smp_103610 Smp_105370 Smp_141610 Smp_158410 Smp_158420 Smp_179950

SHX:	MS3_00003559 MS3_00008098 MS3_00010010 MS3_00010011 MS3_00010066

OVI:	T265_02327 T265_05693 T265_07607 T265_14333 T265_14335

EGL:

EGR_00222

LLON:

135502871 135502971

NVE:	5505945 5509723

EPA:	110234324 110252826

ATEN:

116293307 116305657

ADF:	107344399 107344903 107350137

AMIL:

114967724 114970027

MCAZ:

138027150 138033715

MFOO:

137979172 137979902 137979952 137980006 138003986

PDAM:

113673843 113675535

SPIS:

111333695 111340232

DGT:

114527506

XEN:

124433597

HMG:	100197952 100199148

HSY:	130647676 130647677

RES:

135688855

TAD:	TRIADDRAFT_63119

AQU:	100633221 100634450

ATH:	AT1G02300 AT1G02305 AT4G01610

ALY:	9311036 9325459 9328161

CRB:	17883945 17900801

CSAT:

104707940 104713196 104737620 104738712 104754200 104759653

EUS:	EUTSA_v10008009mg EUTSA_v10028753mg

BRP:	103828445 103836658 103836809

BNA:	106353582 106392482 106426660 106430123 106445455 125595218 125596607

BOE:	106301345 106313065 106337829

RSZ:	108831481 108831565 108839770

THJ:	104815908 104825920

CPAP:

110814176

CIT:

102614215

CIC:	CICLE_v10020859mg

PVY:

116108978

MINC:

123217259 123222402

TCC:

18613845

GRA:	105802230 105802873

GHI:	107912259 107924061 107924551 107941895 121223655

GAB:

108453748

HSYR:

120132661 120135857 120136080 120140582 120181441 120181443 120181447

DZI:	111304909 111314005

EGR:

104434154

RARG:

115747661

GMX:	100778103 100788988

GSJ:	114400215 114407496

PVU:

137814866

VRA:

106757800

VAR:

108329369

VUN:

114178665

VUM:

124840836

CCAJ:

109797052

APRC:

113861211

MTR:	11436390 11436852

TPRA:

123891028 123891029

CAM:	101494142 101495766

PSAT:

127132517 127132518

VVO:	131610493 131622663

LJA:

130730973

ADU:

107492262

AIP:

107646004

AHF:	112695641 112757951

LANG:

109329719 109332004

PCIN:

129296704 129306489

QSA:	O6P43_007351 O6P43_010953

FVE:

101292935

AANS:

126783371

RCN:

112193527

PPER:

18788067

PMUM:

103327235

PAVI:

110764573

PDUL:

117622089

MDM:

103405978

MSYL:

126610766

PXB:

103933562

PCOX:

137707845

MNT:	21405768 21405769

CSAV:

115725062

CSV:

101206928

BHJ:

120090035

MCHA:

111025675

CMAX:

111470792

CMOS:

111439194

CPEP:

111800718

RCU:

8270811

MEAN:

126687335

JCU:

105642738

HBR:	110650398 110661693

MESC:

110613845 110614981

POP:	7455376 7478816 7478817

PEU:	105126206 105126207 105136271

PALZ:

118041153 118044461 118044462

PNZ:	133692668 133692676

JRE:	109000442 109007754

CILL:

122317077

CAVE:

132171963

AGLU:

133851480

QSU:	111990580 112003320

QLO:

115985163

TWL:

120003950

VVI:

100267480

VRI:

117918770

SLY:	101251744 101252354 101252653

SPEN:

107011573 107011654

SOT:	102577522 102605367 102605708

SSTN:

125849504 125849505 125849507

SDUL:

129873339 129873340

CANN:

107858947 107858948 107858950 107858961 107861089 107861094

LBB:	132621154 132621157 132621674

NTA:	107783297 107783298 107830479 107830480

NSY:	104235278 104235279

NTO:	104102612 104102613

NAU:	109209344 109209364

INI:

109152432

ITR:

116025644

SIND:

105162975

OEU:	111391889 111391894

EGT:

105955769

SSPL:

121746853 121752151

SHIS:

125216873

APAN:

127242978

DCR:

108203066

CSIN:

114256972 114301498

RVL:

131312321

AEW:	130751852 130770730

DLT:

127786806

BVG:

104908565

SOE:

110794569

CQI:	110687865 110715677

ATRI:

130812975 130827140

MOF:

131160377

NNU:

104590324

MING:

122079618

TSS:

122658835

PSOM:

113332667 113347104 113347105

OSA:

9267789

DOSA:

Os05g0310500

OBR:	102704389 102715170

OGL:

127773457

BDI:	100828947 100830781

ATS:	109739673 109773816 109780250

TDC:	119286770 119286771 119289149 119294956 119294957 119294960

TAES:

123082317 123086985 123090989 123090993 123096004 123096005 123167940 543297 543298

TUA:	125550517 125550522 125550523

LPER:

127293011 127293012 127293013

LRD:	124704183 124704184 124704185 124704186 124704187

SBI:

110432844

ZMA:

100283781

MFLO:

136542372 136550211

SITA:

101757792 101777949 101783940

SVS:	117834746 117858182 117864968

PVIR:

120643948 120685411 120702684

PHAI:

112893971

PAUA:

133904253

PDA:

103696640

EGU:

105034333

MUS:

103978897

ZOF:	122041769 122046293 122051273 122055811

DCT:	110092127 110092151 110093337

PEQ:	110031705 110035962

AOF:

109831962

MSIN:

131224811

ACAK:

137941096 137959229

NCOL:

116254693 116254750 116263204

ATR:

18430031

CJF:

131029478

SMO:	SELMODRAFT_143272 SELMODRAFT_270024

PPP:	112287856 112291181 112292790

OLU:	OSTLU_5520 OSTLU_94479

OTA:	OT_ostta06g01520 OT_ostta14g01280

BPG:	Bathy05g01560 Bathy06g03130

MIS:	MICPUN_87440 MICPUN_94015

MPP:	MICPUCDRAFT_22888 MICPUCDRAFT_58764

MBR:	MONBRDRAFT_39307

SRE:	PTSG_05183 PTSG_07950

DDI:	DDB_G0283921(ctsB) DDB_G0288563 DDB_G0292462

DPP:	DICPUDRAFT_151351 DICPUDRAFT_155103 DICPUDRAFT_51857

DFA:	DFA_00032(ctsB) DFA_00770 DFA_08585

ACAN:

ACA1_159080 ACA1_198340

TGO:	TGME49_249670

BBES:

BESB_003970

TET:	TTHERM_00079660 TTHERM_00079670 TTHERM_00083480 TTHERM_00083500 TTHERM_00348660 TTHERM_00641150

PTM:	GSPATT00007263001 GSPATT00009658001 GSPATT00011133001 GSPATT00011545001 GSPATT00012576001 GSPATT00030174001 GSPATT00036656001 GSPATT00038265001

AAF:	AURANDRAFT_32318 AURANDRAFT_32974

NGR:

NAEGRDRAFT_29772 NAEGRDRAFT_30183 NAEGRDRAFT_30261 NAEGRDRAFT_3032 NAEGRDRAFT_32592 NAEGRDRAFT_33120 NAEGRDRAFT_33141 NAEGRDRAFT_3397 NAEGRDRAFT_34133 NAEGRDRAFT_51797 NAEGRDRAFT_66115 NAEGRDRAFT_71406 NAEGRDRAFT_72036 NAEGRDRAFT_72389 NAEGRDRAFT_73314 NAEGRDRAFT_75331 NAEGRDRAFT_75481 NAEGRDRAFT_76604 NAEGRDRAFT_77096 NAEGRDRAFT_77381 NAEGRDRAFT_81104 NAEGRDRAFT_81872

TVA:	TVAG_2v0589130

GLA:	GL50803_0010217 GL50803_0014019 GL50803_0016468 GL50803_0016779 GL50803_0017516

SSAO:

94295801(SS50377_21778) 94295811(SS50377_21788) 94295925(SS50377_21902) 94296466(SS50377_22443) 94296472(SS50377_22449) 94298056(SS50377_24033) 94299123(SS50377_25100) 94299126(SS50377_25103) 94299156(SS50377_25133) 94299157(SS50377_25134) 94299220(SS50377_25197) 94300789(SS50377_26766) 94301231(SS50377_27208) 94301235(SS50377_27212) 94301435(SS50377_27412)

EHX:	EMIHUDRAFT_355058

GTT:	GUITHDRAFT_136197 GUITHDRAFT_73372 GUITHDRAFT_78289

DMM:	dnm_017330

» show all

Reference

1 [PMID:7458901]

Authors

Bond JS, Barrett AJ.

Title

Degradation of fructose-1,6-bisphosphate aldolase by cathepsin B.

Journal

Biochem J 189:17-25 (1980)
DOI:10.1042/bj1890017

Reference

2 [PMID:7043200]

Authors

Barrett AJ, Kirschke H.

Title

Cathepsin B, Cathepsin H, and cathepsin L.

Journal

Methods Enzymol 80 Pt C:535-61 (1981)
DOI:10.1016/s0076-6879(81)80043-2

Reference

3 [PMID:3312190]

Authors

Polgar L, Csoma C.

Title

Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B.

Journal

J Biol Chem 262:14448-53 (1987)

Reference

Authors

Barrett AJ, Buttle DJ, Mason RW.

Title

Lysosomal cysteine proteinases.

Journal

ISI Atlas of Science Biochemistry 1:256-260 (1988)

Reference

5 [PMID:3342870]

Authors

Kirschke H, Wikstrom P, Shaw E.

Title

Active center differences between cathepsins L and B: the S1 binding region.

Journal

FEBS Lett 228:128-30 (1988)
DOI:10.1016/0014-5793(88)80600-8

Other DBs

ExplorEnz - The Enzyme Database:

3.4.22.1

IUBMB Enzyme Nomenclature:

3.4.22.1

ExPASy - ENZYME nomenclature database:

3.4.22.1

BRENDA, the Enzyme Database:

3.4.22.1

CAS:

9047-22-7

DBGET integrated database retrieval system