| Entry |
|
|---|
| Name |
picornain 2A;
picornavirus endopeptidase 2A;
poliovirus protease 2A;
rhinovirus protease 2A;
2A protease;
2A proteinase;
protease 2A;
proteinase 2Apro;
picornaviral 2A proteinase;
Y-G proteinase 2A;
poliovirus proteinase 2A;
poliovirus protease 2Apro
|
|---|
| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
|
|---|
| Reaction(IUBMB) |
Selective cleavage of Tyr!Gly bond in picornavirus polyprotein
|
|---|
| Comment |
From entero-, rhino-, aphto- and cardioviruses. Smaller than the homologous picornain 3C, which is also in peptidase family C3 (picornain 3C family)
|
|---|
| History |
EC 3.4.22.29 created 1992
|
|---|
| Orthology |
| K25293 | Enterovirus protease 2A |
|
|---|
| Reference |
|
|---|
| Authors |
Bazan JF, Fletterick RJ. |
|---|
| Title |
Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Konig H, Rosenwirth B. |
|---|
| Title |
Purification and partial characterization of poliovirus protease 2A by means of a functional assay. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Krausslich HG, Wimmer E. |
|---|
| Title |
Viral proteinases. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.22.29 |
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|---|
