KEGG   ENZYME: 3.4.24.19
Entry
EC 3.4.24.19                Enzyme                                 

Name
procollagen C-endopeptidase;
procollagen C-terminal proteinase;
carboxyprocollagen peptidase;
procollagen C-terminal peptidase;
procollagen C-proteinase;
procollagen C-terminal proteinase;
procollagen carboxypeptidase;
procollagen carboxy-terminal proteinase;
procollagen peptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of the C-terminal propeptide at Ala!Asp in type I and II procollagens and at Arg!Asp in type III
Comment
A 100 kDa endopeptidase the activity of which is increased by Ca2+ and by an enhancer glycoprotein. In peptidase family M12 (astacin family)
History
EC 3.4.24.19 created 1992
Orthology
K05502  bone morphogenetic protein 1
Genes
HSA: 649(BMP1)
PTR: 464042(BMP1)
PPS: 100979179(BMP1)
GGO: 101145590(BMP1)
PON: 100453093(BMP1)
NLE: 100596014(BMP1)
MCC: 707596(BMP1)
MCF: 102116822(BMP1)
CSAB: 103215447(BMP1)
CATY: 105579280(BMP1)
PANU: 101024113(BMP1)
RRO: 104663959(BMP1)
RBB: 108521321(BMP1)
TFN: 117093121(BMP1)
PTEH: 111545679(BMP1)
SBQ: 101042414(BMP1)
MMUR: 105857139(BMP1)
MMU: 12153(Bmp1)
MCAL: 110308919(Bmp1)
MPAH: 110325211(Bmp1)
RNO: 83470(Bmp1)
MCOC: 116084242(Bmp1)
MUN: 110551677(Bmp1)
CGE: 100751120(Bmp1)
PLEU: 114698807(Bmp1)
NGI: 103748138(Bmp1)
HGL: 101713810(Bmp1)
CPOC: 100729039(Bmp1)
CCAN: 109690450(Bmp1)
OCU: 100356758(BMP1)
OPI: 101523216(BMP1)
TUP: 102480045(BMP1)
CFA: 100856514(BMP1)
VVP: 112926748(BMP1)
VLG: 121497269(BMP1)
AML: 100477539(BMP1)
UMR: 103673342(BMP1)
UAH: 113270006(BMP1)
ORO: 101382533(BMP1)
ELK: 111156717
MPUF: 101690300(BMP1)
EJU: 114217518(BMP1)
MLX: 118022074(BMP1)
FCA: 101093350(BMP1)
PYU: 121039873(BMP1)
PBG: 122472468(BMP1)
PTG: 102972893(BMP1)
PPAD: 109277354(BMP1)
AJU: 106981094(BMP1)
HHV: 120239461(BMP1)
BTA: 510360(BMP1)
BOM: 102266088(BMP1)
BBUB: 102396219(BMP1)
CHX: 102179476(BMP1)
OAS: 101122334(BMP1)
ODA: 120865419(BMP1)
CCAD: 122431644(BMP1)
SSC: 100156461(BMP1)
CFR: 102521071(BMP1)
CBAI: 105068985(BMP1)
CDK: 105103080(BMP1)
BACU: 103005385(BMP1)
LVE: 103091450(BMP1)
OOR: 101269303(BMP1)
DLE: 111169000(BMP1)
PCAD: 102978081(BMP1)
PSIU: 116755449(BMP1)
ECB: 100056914(BMP1)
EPZ: 103566261(BMP1)
EAI: 106847695(BMP1)
MYB: 102239069(BMP1)
MYD: 102754055(BMP1)
MMYO: 118658390(BMP1)
MLF: 102427373(BMP1)
MNA: 107536087(BMP1)
PKL: 118725839(BMP1)
HAI: 109382422(BMP1)
DRO: 112305145(BMP1)
SHON: 118975002(BMP1)
AJM: 119054656(BMP1)
PDIC: 114502433(BMP1)
MMF: 118615271(BMP1)
RFQ: 117038285(BMP1)
PALE: 102887209(BMP1)
PGIG: 120606621(BMP1)
RAY: 107509198(BMP1)
MJV: 108393179(BMP1)
TOD: 119234842(BMP1)
LAV: 100673680(BMP1)
TMU: 101359122
MDO: 100033098(BMP1)
GAS: 123236955(BMP1)
SHR: 100932831(BMP1)
PCW: 110200409(BMP1)
OAA: 100087374(BMP1)
APLA: 101795070(BMP1)
TGU: 115498187(BMP1)
LSR: 110479426(BMP1)
SCAN: 103824949(BMP1)
PMOA: 120497192(BMP1)
OTC: 121346808(BMP1)
PRUF: 121366000(BMP1)
GFR: 102040585(BMP1)
FAB: 101807676(BMP1)
PHI: 102099474(BMP1)
PMAJ: 107213953(BMP1)
CCAE: 111938758(BMP1)
CCW: 120411161(BMP1)
ETL: 114070072(BMP1)
FPG: 101918385(BMP1)
FCH: 102051643(BMP1)
CLV: 102094799(BMP1)
EGZ: 104127935
NNI: 104016031(BMP1)
AAM: 106499973(BMP1)
AROW: 112973614(BMP1)
NPD: 112949870(BMP1)
DNE: 112996692(BMP1)
ASN: 102376631(BMP1)
AMJ: 102574594(BMP1)
PSS: 102460646(BMP1)
CMY: 102937822(BMP1)
CPIC: 101938610(BMP1)
TST: 117872976(BMP1)
CABI: 116836917(BMP1)
MRV: 120397967(BMP1)
ACS: 100568138(bmp1)
PVT: 110072169(BMP1)
SUND: 121933497(BMP1)
PBI: 103064624(BMP1)
PMUR: 107289251(BMP1)
TSR: 106549316
PGUT: 117674753(BMP1)
VKO: 123027064(BMP1)
PMUA: 114585596(BMP1)
ZVI: 118096805(BMP1)
GJA: 107113015(BMP1)
XLA: 397872(bmp1.L) 399093(bmp1.S)
XTR: 733960(bmp1)
NPR: 108798464(BMP1)
DRE: 559877(bmp1b) 572452(bmp1a)
CCAR: 109109073
IPU: 108265517(bmp1) 108276587
PHYP: 113533637(bmp1) 113544093
EEE: 113578135
TRU: 101068949(bmp1) 101072844
ELY: 117252445(bmp1a) 117269816
PLEP: 121945014(bmp1a) 121959616
SLUC: 116035078 116053872(bmp1a)
ECRA: 117944235(bmp1a) 117959405
GAT: 120830810(bmp1a) 120832220
PPUG: 119224547(bmp1a) 119226498
MSAM: 119891092(bmp1a) 119914448
CUD: 121509636(bmp1a) 121525241
OAU: 116310222(bmp1a) 116322545
OML: 112148425(bmp1a) 112163076
XHE: 116724780 116729501(bmp1)
GAF: 122819389 122827965(bmp1a)
CVG: 107092678 107093872(bmp1)
CTUL: 119783946(bmp1a) 119789025
NFU: 107373116 107393753(bmp1)
KMR: 108232606 108236587(bmp1a)
SSEN: 122769038(bmp1a) 122781938
HHIP: 117768039(bmp1a) 117771850
LCF: 108878376(bmp1) 108879830
XGL: 120805554(bmp1a) 120806693
ELS: 105014263(bmp1) 105014870
PKI: 111838614(bmp1) 111857333
AANG: 118213089 118237278(bmp1a)
LOC: 102688693(bmp1)
LCM: 102357697(BMP1)
CMK: 103190854
RTP: 109911454
MDL: 103573542
TUT: 107359882
PCAN: 112570286
PMAX: 117314954
NVE: 5522383
AMIL: 114955126
 » show all
Reference
1  [PMID:3905801]
  Authors
Hojima Y, van der Rest M, Prockop DJ.
  Title
Type I procollagen carboxyl-terminal proteinase from chick embryo tendons. Purification and characterization.
  Journal
J Biol Chem 260:15996-6003 (1985)
Reference
2  [PMID:2689170]
  Authors
Kessler E, Adar R.
  Title
Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a 55-kDa enhancer glycoprotein.
  Journal
Eur J Biochem 186:115-21 (1989)
DOI:10.1111/j.1432-1033.1989.tb15184.x
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.19
IUBMB Enzyme Nomenclature: 3.4.24.19
ExPASy - ENZYME nomenclature database: 3.4.24.19
BRENDA, the Enzyme Database: 3.4.24.19
CAS: 68651-95-6

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