KEGG   ENZYME: 3.4.24.59Help
Entry
EC 3.4.24.59                Enzyme                                 

Name
mitochondrial intermediate peptidase;
mitochondrial intermediate precursor-processing proteinase;
MIP
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion
Comment
A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family)
History
EC 3.4.24.59 created 1993
Orthology
K01410  mitochondrial intermediate peptidase
Genes
HSA: 4285(MIPEP)
PTR: 467228(MIPEP)
PPS: 100984556(MIPEP)
GGO: 101137911(MIPEP)
PON: 100171586(MIPEP)
NLE: 100606156(MIPEP)
MCC: 707131(MIPEP)
MCF: 101865693(MIPEP)
CSAB: 103249000(MIPEP)
RRO: 104669088 104675183(MIPEP)
RBB: 108531177(MIPEP)
CJC: 100393887(MIPEP)
SBQ: 101049620(MIPEP)
MMU: 70478(Mipep)
RNO: 81684(Mipep)
CGE: 100762716(Mipep)
NGI: 103727184(Mipep)
HGL: 101696293(Mipep)
OCU: 100355371(MIPEP)
TUP: 102494013(MIPEP)
CFA: 477338(MIPEP)
AML: 100466665(MIPEP)
UMR: 103664393(MIPEP)
ORO: 101377428(MIPEP)
FCA: 101084847(MIPEP)
PTG: 102960672(MIPEP)
AJU: 106988936(MIPEP)
BTA: 517531(MIPEP)
BOM: 102279227(MIPEP)
BIU: 109566845(MIPEP)
PHD: 102335405(MIPEP)
CHX: 102169023(MIPEP)
OAS: 101116412(MIPEP)
SSC: 100155148(MIPEP)
CFR: 102507392(MIPEP)
CDK: 105096410(MIPEP)
BACU: 103011954(MIPEP)
LVE: 103089766(MIPEP)
OOR: 101290249(MIPEP)
ECB: 100058095(MIPEP)
EAI: 106832449(MIPEP)
MYB: 102251949(MIPEP)
MYD: 102754588 102764825(MIPEP)
HAI: 109387502(MIPEP)
RSS: 109449861(MIPEP)
PALE: 102893175(MIPEP)
LAV: 100676057(MIPEP)
TMU: 101348130
MDO: 100024478(MIPEP)
SHR: 100923419(MIPEP)
OAA: 100089996(MIPEP)
GGA: 418942(MIPEP)
MGP: 100548274(MIPEP)
CJO: 107308297(MIPEP)
APLA: 101800508(MIPEP)
ACYG: 106040392(MIPEP)
TGU: 100217619(MIPEP)
GFR: 102041723(MIPEP)
FAB: 101808582(MIPEP)
PHI: 102104433(MIPEP)
PMAJ: 107202032(MIPEP)
CCW: 104690098(MIPEP)
FPG: 101912013(MIPEP)
FCH: 102050134(MIPEP)
CLV: 102093974(MIPEP)
EGZ: 104131696(MIPEP)
AAM: 106500405(MIPEP)
ASN: 102387822(MIPEP)
AMJ: 102565859(MIPEP)
PSS: 102448704(MIPEP)
CMY: 102932805(MIPEP)
CPIC: 101931175(MIPEP)
ACS: 100565494(mipep)
PVT: 110088650(MIPEP)
PBI: 103051948(MIPEP)
GJA: 107117273(MIPEP)
XLA: 108708717(mipep.L) 108709016(mipep.S)
XTR: 100497804(mipep)
NPR: 108800063(MIPEP)
DRE: 100005953(mipep) 557349(si:ch73-1a9.4)
SANH: 107679518 107699841(mipep)
CCAR: 109058308(mipep) 109072330
IPU: 108277681(mipep)
AMEX: 103023218(mipep)
TRU: 101077714(mipep)
LCO: 104921133(mipep)
MZE: 101479497(mipep)
OLA: 101155870(mipep)
XMA: 102233165(mipep)
PRET: 103474376(mipep)
NFU: 107380675(mipep)
CSEM: 103377613(mipep) 103399496
LCF: 108873787(mipep)
HCQ: 109512836(mipep)
BPEC: 110171875(mipep)
ELS: 105007223 105019419(mipep)
SFM: 108932349(mipep)
LCM: 102353862(MIPEP)
CMK: 103183271(mipep)
CIN: 100179312(mipep)
SPU: 585883
APLC: 110988415
SKO: 102800854
DSI: Dsimw501_GD10350(Dsim_GD10350)
MDE: 101891459
AAG: 110675343
AME: 412784
BIM: 100740934
BTER: 100642335
SOC: 105201761
AEC: 105151479
PBAR: 105425223
HST: 105187249
CFO: 105252786
LHU: 105679570
PGC: 109857877
NVI: 100119769
TCA: 662652
NVL: 108569082
BMOR: 101741797
PRAP: 111001867
API: 100159686
DNX: 107166347
ZNE: 110840240
FCD: 110858809
TUT: 107366416
CEL: CELE_Y67H2A.7(Y67H2A.7)
CBR: CBG01792
BMY: Bm1_11870
TSP: Tsp_03383
MYI: 110466918
OBI: 106879897
SHX: MS3_02675
EPA: 110240373
ADF: 107331392
HMG: 100203118
AQU: 105313764
ATH: AT5G51540
CRB: 17874842
BRP: 103857178
BOE: 106329452
THJ: 104811515
CPAP: 110823525
CIT: 102620869
TCC: 18605385
GRA: 105801745
GHI: 107904641
DZI: 111289717
EGR: 104424338
GMX: 100794972
VRA: 106762665
VAR: 108334127
CCAJ: 109813038
CAM: 101509522
LJA: Lj0g3v0319349.1(Lj0g3v0319349.1) Lj0g3v0319349.2(Lj0g3v0319349.2)
ADU: 107491534
AIP: 107641590
LANG: 109328828
FVE: 101314141
PPER: 18787218
PAVI: 110764650
CSV: 101210211
CMO: 103483995
MCHA: 111011592
CMAX: 111471087
CMOS: 111446997
CPEP: 111782043
RCU: 8266048
JCU: 105648591
HBR: 110648092
POP: 7481823
JRE: 109014092
VVI: 100262804
SLY: 101249800
SPEN: 107015509
SOT: 102584257
CANN: 107863420
NSY: 104225794
NTO: 104111565
INI: 109193780
SIND: 105160579
OEU: 111406064
HAN: 110872840
LSV: 111904041
DCR: 108223767
BVG: 104888673
SOE: 110782383
NNU: 104611543
OSA: 4341884
DOSA: Os06t0686500-01(Os06g0686500)
OBR: 102717808
BDI: 100825697
ATS: 109780722(LOC109780722)
SBI: 8061641
ZMA: 100384686
SITA: 101782826
EGU: 105043263
MUS: 103983048
DCT: 110100890
AOF: 109837777
ATR: 18444248
PPP: 112293047
MNG: MNEG_0600
OLU: OSTLU_625
APRO: F751_3907
SCE: YKL134C(OCT1)
ERC: Ecym_6099
KMX: KLMA_30114(OCT1)
NCS: NCAS_0A04280(NCAS0A04280)
NDI: NDAI_0E02010(NDAI0E02010)
TPF: TPHA_0G02390(TPHA0G02390)
TBL: TBLA_0I00710(TBLA0I00710)
TDL: TDEL_0A02080(TDEL0A02080)
KAF: KAFR_0D02950(KAFR0D02950)
PIC: PICST_89481(OCT1)
CAL: CAALFM_C600340CA(CaO19.1195)
CAUR: QG37_03309
SLB: AWJ20_321(OCT1)
NCR: NCU02063
NTE: NEUTE1DRAFT149413(NEUTE1DRAFT_149413)
MGR: MGG_00487
MAW: MAC_01004
MAJ: MAA_05729
CMT: CCM_02324
MBE: MBM_01310
ANG: ANI_1_762094(An11g05710)
ABE: ARB_04967
TVE: TRV_06295
PTE: PTT_01260
SPO: SPAC1F3.10c(oct1)
MRR: Moror_317
SCM: SCHCODRAFT_13586(mip)
ABP: AGABI1DRAFT67360(mip)
ABV: AGABI2DRAFT213738(AGABI2DRAFT_213738)
SLA: SERLADRAFT_444624(mip1)
MGL: MGL_3874
DFA: DFA_04512
PYO: PY17X_1355900(PY06253)
PCB: PCHAS_135540(PC000493.04.0)
TAN: TA20475
TPV: TP01_0515
BBO: BBOV_III002610(17.m07249)
SMIN: v1.2.007151.t2(symbB.v1.2.007151.t2) v1.2.007151.t4(symbB.v1.2.007151.t4) v1.2.007151.t5(symbB.v1.2.007151.t5)
SPAR: SPRG_00112
TCR: 504147.80
 » show all
Taxonomy
Reference
1  [PMID:1560019]
  Authors
Isaya G, Kalousek F, Rosenberg LE.
  Title
Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase.
  Journal
J Biol Chem 267:7904-10 (1992)
Reference
2  [PMID:1518864]
  Authors
Isaya G, Kalousek F, Rosenberg LE.
  Title
Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue.
  Journal
Proc Natl Acad Sci U S A 89:8317-21 (1992)
DOI:10.1073/pnas.89.17.8317
  Sequence
[rno:81684]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.59
IUBMB Enzyme Nomenclature: 3.4.24.59
ExPASy - ENZYME nomenclature database: 3.4.24.59
BRENDA, the Enzyme Database: 3.4.24.59
CAS: 136447-30-8

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