KEGG   ENZYME: 3.4.24.66
Entry
EC 3.4.24.66                Enzyme                                 

Name
choriolysin L;
teleost hatching enzyme (component);
low choriolytic enzyme (LCE)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of casein and small molecule substrates such as succinyl-Leu-Leu-Val-Tyr!7-(4-methyl)coumarylamide
Comment
Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin H. A 24 kDa peptidase family M12 (astacin family)
History
EC 3.4.24.66 created 1995
Orthology
K18542  choriolysin L
Genes
TRU: 777973(fglce)
TNG: GSTEN00020735G001
LCO: 104940076
MZE: 101476186 106676582
ONL: 100703510
OLA: 100049451(lce)
CVG: 107090859
NFU: 107378082
KMR: 108231855
ALIM: 106518582
AOCE: 111573796
CSEM: 103381002
POV: 109632545
LCF: 108896859
SDU: 111235837
SLAL: 111672534
HCQ: 109531019
BPEC: 110168286
MALB: 109962249
OTW: 112243681
ELS: 105023563
AAG: 5574405
AALB: 109419214
API: 100574746
BTAB: 109044757
ZNE: 110827431
FCD: 110855108
PVM: 113828072
TUT: 107371393
EPA: 110234469
 » show all
Reference
1
  Authors
Yasumasu, S., Iuchi, I. and Yamagami, K.
  Title
Medaka hatching enzyme consists of two kinds of proteases which act cooperatively.
  Journal
Zool Sci 5:191-195 (1988)
Reference
2  [PMID:2656665]
  Authors
Yasumasu S, Iuchi I, Yamagami K.
  Title
Isolation and some properties of low choriolytic enzyme (LCE), a component of the hatching enzyme of the teleost, Oryzias latipes.
  Journal
J Biochem (Tokyo) 105:212-8 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122641
Reference
3  [PMID:1730389]
  Authors
Yasumasu S, Katow S, Hamazaki TS, Iuchi I, Yamagami K.
  Title
Two constituent proteases of a teleostean hatching enzyme: concurrent syntheses and packaging in the same secretory granules in discrete arrangement.
  Journal
Dev Biol 149:349-56 (1992)
DOI:10.1016/0012-1606(92)90290-W
Reference
4  [PMID:1397682]
  Authors
Yasumasu S, Yamada K, Akasaka K, Mitsunaga K, Iuchi I, Shimada H, Yamagami K.
  Title
Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development.
  Journal
Dev Biol 153:250-8 (1992)
DOI:10.1016/0012-1606(92)90110-3
  Sequence
[ola:100049451]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.66
IUBMB Enzyme Nomenclature: 3.4.24.66
ExPASy - ENZYME nomenclature database: 3.4.24.66
BRENDA, the Enzyme Database: 3.4.24.66
CAS: 177529-15-6

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