KEGG   ENZYME: 3.4.24.66
Entry
EC 3.4.24.66                Enzyme                                 
Name
choriolysin L;
teleost hatching enzyme (component);
low choriolytic enzyme (LCE)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of casein and small molecule substrates such as succinyl-Leu-Leu-Val-Tyr!7-(4-methyl)coumarylamide
Comment
Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin H. A 24 kDa peptidase family M12 (astacin family)
History
EC 3.4.24.66 created 1995
Orthology
K18542  choriolysin L
Genes
TRU777973(fglce)
TNGGSTEN00020735G001
LCO104940076
CGOB115028844
ELY117270808
EFO125897303
PLEP121955371
SLUC116066133
ECRA117961966
ESP116706235
GAT100190865(galce)
PPUG119195387 119195388 119195389
MSAM119908817 119908820
SCHU122863640
CUD121521303
ALAT119012390
MZE101476186 106676582
ONL100703510
OAU116332236 116332252
OLA100049451(lce)
OML112157895
PLAI106949868
CVG107090859
CTUL119773101
GMU124882439
NFU107378082
KMR108231855
ALIM106518582
NWH119418488 119418489
AOCE111573796
MCEP124999041
CSEM103381002
POV109632545
SSEN122758371 122783655
HHIP117758503
HSP118099633
LCF108896859
SDU111235837
SLAL111672534
XGL120789184
HCQ109531019
SSCV125989906
BPEC110168286
MALB109962249
SASA100302417 106613193
STRU115163983 115204953
OTW112243681 112266172
OMY100359378(rblce) 110503164 118944670
OGO123993888 124005757
ONE115119784 115142216
SALP111949951 111960782
SNH120018727 120028779
CCLU121567210
ELS105023563
PSPA121308983
AALI118459483
AAG5574405
AALB109419214
CQUCpipJ_CPIJ013386
CPII120425610
API100574746
BTAB109044757
ZNE110827431
FCD110855108
PVM113828072
PCHN125036433
HAME121855840
PCLA123750195
ESN126992137 127009118
ISCIscW_ISCW024332
CSCU111617071 111618635 111631999
PTEP107441045 107443125
LPOL106476015
PMEO129592854
NAINECAME_09364 NECAME_11359
EPA110234469
 » show all
Reference
1
  Authors
Yasumasu, S., Iuchi, I. and Yamagami, K.
  Title
Medaka hatching enzyme consists of two kinds of proteases which act cooperatively.
  Journal
Zool Sci 5:191-195 (1988)
Reference
2  [PMID:2656665]
  Authors
Yasumasu S, Iuchi I, Yamagami K.
  Title
Isolation and some properties of low choriolytic enzyme (LCE), a component of the hatching enzyme of the teleost, Oryzias latipes.
  Journal
J Biochem (Tokyo) 105:212-8 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122641
Reference
3  [PMID:1730389]
  Authors
Yasumasu S, Katow S, Hamazaki TS, Iuchi I, Yamagami K.
  Title
Two constituent proteases of a teleostean hatching enzyme: concurrent syntheses and packaging in the same secretory granules in discrete arrangement.
  Journal
Dev Biol 149:349-56 (1992)
DOI:10.1016/0012-1606(92)90290-W
Reference
4  [PMID:1397682]
  Authors
Yasumasu S, Yamada K, Akasaka K, Mitsunaga K, Iuchi I, Shimada H, Yamagami K
  Title
Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development.
  Journal
Dev Biol 153:250-8 (1992)
DOI:10.1016/0012-1606(92)90110-3
  Sequence
[ola:100049451]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.66
IUBMB Enzyme Nomenclature: 3.4.24.66
ExPASy - ENZYME nomenclature database: 3.4.24.66
BRENDA, the Enzyme Database: 3.4.24.66
CAS: 177529-15-6

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