KEGG   ENZYME: 3.4.24.67Help
Entry
EC 3.4.24.67                Enzyme                                 

Name
choriolysin H;
teleost hatching enzyme (component);
high choriolytic enzyme (HCE)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of casein and small molecule substrates such as succinyl-Leu-Leu-Val-Tyr!7-(4-methyl)coumarylamide
Comment
Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin L. A 25.5 kDa peptidase in family M12 (astacin family)
History
EC 3.4.24.67 created 1995
Orthology
K18543  choriolysin H
Genes
DRE: 407971(he1.2)
SRX: 107715261 107739316 107739317 107739318 107751463 107751483 107751488 107756160
SANH: 107653533 107653536 107653568 107653569 107653570 107653608 107653609 107669394 107687862 107687863 107687881 107687887 107699967
SGH: 107548229 107565490 107565491 107565492 107571701 107571702 107600986 107600988
CCAR: 109045423 109045988 109047084 109047085 109060047 109061795 109061816 109061828 109061829 109061830 109088636 109088637 109091756 109093875
IPU: 108259525 108259527
AMEX: 111191931 111197481 111197482 111197483
TRU: 101062281 101073853 101077206 101079564 101079794 778019(fghce)
TNG: GSTEN00012859G001
LCO: 104919773 104927714 104935188 109137006 109141327 109141328 109141329 109141330
HCQ: 109509944
BPEC: 110159557
 » show all
Taxonomy
Reference
1  [PMID:4652273]
  Authors
Yamagami K.
  Title
Isolation of a choriolytic enzyme (hatching enzyme) of the teleost, Oryzias latipes.
  Journal
Dev Biol 29:343-8 (1972)
DOI:10.1016/0012-1606(72)90074-7
Reference
2  [PMID:2656664]
  Authors
Yasumasu S, Iuchi I, Yamagami K.
  Title
Purification and partial characterization of high choriolytic enzyme (HCE), a component of the hatching enzyme of the teleost, Oryzias latipes.
  Journal
J Biochem (Tokyo) 105:204-11 (1989)
Reference
3  [PMID:2751672]
  Authors
Yasumasu S, Katow S, Umino Y, Iuchi I, Yamagami K.
  Title
A unique proteolytic action of HCE, a constituent protease of a fish hatching enzyme: tight binding to its natural substrate, egg envelope.
  Journal
Biochem Biophys Res Commun 162:58-63 (1989)
DOI:10.1016/0006-291X(89)91961-X
Reference
4  [PMID:1397682]
  Authors
Yasumasu S, Yamada K, Akasaka K, Mitsunaga K, Iuchi I, Shimada H, Yamagami K.
  Title
Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development.
  Journal
Dev Biol 153:250-8 (1992)
DOI:10.1016/0012-1606(92)90110-3
  Sequence
Reference
5  [PMID:8112467]
  Authors
Lee KS, Yasumasu S, Nomura K, Iuchi I.
  Title
HCE, a constituent of the hatching enzymes of Oryzias latipes embryos, releases unique proline-rich polypeptides from its natural substrate, the hardened chorion.
  Journal
FEBS Lett 339:281-4 (1994)
DOI:10.1016/0014-5793(94)80431-1
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.67
IUBMB Enzyme Nomenclature: 3.4.24.67
ExPASy - ENZYME nomenclature database: 3.4.24.67
BRENDA, the Enzyme Database: 3.4.24.67
CAS: 177529-16-7

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