KEGG   ENZYME: 3.5.1.105
Entry
EC 3.5.1.105                Enzyme                                 

Name
chitin disaccharide deacetylase;
chitobiose amidohydolase;
COD;
chitin oligosaccharide deacetylase;
chitin oligosaccharide amidohydolase;
2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
N,N'-diacetylchitobiose acetylhydrolase
Reaction(IUBMB)
N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate [RN:R11889]
Reaction(KEGG)
R11889
Substrate
N,N'-diacetylchitobiose [CPD:C01674];
H2O [CPD:C00001]
Product
N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine [CPD:C21747];
acetate [CPD:C00033]
Comment
Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains. Besides being a nutrient, the heterodisaccharide product 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus [2]. In contrast to EC 3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide [1,3]. It also deacetylates the chitin trisaccharide with lower efficiency [3]. No activity with higher polymers of GlcNAc [1,3].
History
EC 3.5.1.105 created 2010
Orthology
K03478  chitin disaccharide deacetylase
K18454  chitin disaccharide deacetylase
Genes
ECO: b1733(chbG)
ECJ: JW1722(chbG)
ECD: ECDH10B_1871(chbG)
EBW: BWG_1546(chbG)
ECOK: ECMDS42_1408(chbG)
ECE: Z2763(ydjC)
ECS: ECs2439
ECF: ECH74115_2451
ETW: ECSP_2301(chbG)
ELX: CDCO157_2273
EOI: ECO111_2244(chbG)
EOJ: ECO26_2508(chbG)
EOH: ECO103_1926(chbG)
ECOO: ECRM13514_2230(ydjC)
ECOH: ECRM13516_2135(ydjC)
ESL: O3K_11300
ESO: O3O_14320
ESM: O3M_11280
ECK: EC55989_1901(chbG)
ECG: E2348C_1861(chbG)
EOK: G2583_2179(chbG)
ELH: ETEC_1765
ECP: ECP_1679
ENA: ECNA114_1778(ydjC)
ECOS: EC958_1954(ydjC)
ECV: APECO1_802(ydjC)
ECY: ECSE_1903
ECR: ECIAI1_1793(chbG)
ECQ: ECED1_1935(chbG)
EUM: ECUMN_2022(chbG)
ECT: ECIAI39_1321(chbG)
EBR: ECB_01702(ydjC)
EBL: ECD_01702(chbG)
EBE: B21_01690(chbG)
EBD: ECBD_1912
ECI: UTI89_C1926(ydjC)
ECZ: ECS88_1785(chbG)
ECC: c2132(ydjC)
ELO: EC042_1898(chbG)
ESE: ECSF_1594
EAB: ECABU_c19890(ydjC)
EDJ: ECDH1ME8569_1677(chbG)
ELW: ECW_m1902(chbG)
ELL: WFL_09325
ELC: i14_1952(ydjC)
ELD: i02_1952(ydjC)
ELF: LF82_0294(chbG)
ECOJ: P423_09225
EFE: EFER_1334(chbG)
ESZ: FEM44_18280(chbG) FEM44_23595(chbG)
STY: STY1796
STT: t1196
STM: STM1317(celG)
SEO: STM14_1599(celG)
SEY: SL1344_1252(celG)
SEJ: STMUK_1284(celG)
SEB: STM474_1322(chbg)
SENI: CY43_06705
SPT: SPA1527(celG)
SEK: SSPA1418
SEI: SPC_2413(celG)
SEC: SCH_1338(celG)
SHB: SU5_01936
SENS: Q786_08670
SED: SeD_A2027
SEG: SG1799
SEL: SPUL_1134
SET: SEN1726
SENA: AU38_08935
SENO: AU37_08940
SENV: AU39_08945
SENQ: AU40_09985
SENL: IY59_09140
SEEP: I137_05210
SENE: IA1_06500
SBG: SBG_1171
SBZ: A464_1272
SFL: SF1495(ydjC)
SFX: S1612(ydjC)
SFV: SFV_1487(ydjC)
SFN: SFy_2144
SFS: SFyv_2196
SSN: SSON_1425(ydjC)
ENC: ECL_02434
ECLX: LI66_09075
ECLY: LI62_09850
ECLZ: LI64_09140
ECLO: ENC_14330
EEC: EcWSU1_01795(ydjC)
ECHG: FY206_10485(chbG)
EBG: FAI37_20255(chbG)
KPN: KPN_01235(ydjC)
KPU: KP1_2268
KPP: A79E_2951
KPR: KPR_2284
KPJ: N559_3045
KPNU: LI86_15830
KPNK: BN49_2371
KVA: Kvar_3079
KPE: KPK_3206
KOX: KOX_18220
KOE: A225_2500
EAE: EAE_21530
EAR: CCG29631
KLW: DA718_16410(chbG)
CRO: ROD_07511(chbG) ROD_13231(chbG)
CKO: CKO_01758
CPOT: FOB25_01330(chbG)
CAMA: F384_05985
CTEL: GBC03_18725(chbG)
CITZ: E4Z61_03760(chbG)
CARS: E1B03_11845(chbG)
KOR: AWR26_05150(chbG)
KPSE: IP581_18370(chbG)
KIE: NCTC12125_01650(chbF_1)
KAS: KATP_25780(chbG)
LER: GNG29_09480(chbG)
LEA: GNG26_09140(chbG)
METY: MRY16398_22490(chbG)
YRE: HEC60_04235(chbG)
SGOE: A8O29_013555(chbG)
PDZ: HHA33_12790(chbG)
EBF: D782_2540
YPE: YPO2682
YPK: y1255
YPH: YPC_3176
YPA: YPA_2411
YPN: YPN_1168
YPM: YP_2484
YPG: YpAngola_A3572(chbG)
YPZ: YPZ3_2366
YPD: YPD4_2346
YPX: YPD8_2345
YPW: CH59_3562
YPJ: CH55_1489
YPV: BZ15_851
YPL: CH46_2427
YPS: YPTB2927
YPO: BZ17_3701
YPI: YpsIP31758_1095(chbG)
YPY: YPK_1148
YPB: YPTS_3043
YPQ: DJ40_3562
YPU: BZ21_2232
YPR: BZ20_3245
YPC: BZ23_2512
YPF: BZ19_2298
YEN: YE0972
YEY: Y11_42061
YEW: CH47_375
YET: CH48_630
YAL: AT01_3453
YFR: AW19_126
YIN: CH53_711
YKR: CH54_1537
YRO: CH64_1564
YRU: BD65_607
YCA: F0T03_05380(chbG)
YMO: HRD69_20405(chbG)
SMAR: SM39_0157(chbG)
SMAC: SMDB11_0155(chbG)
SMW: SMWW4_v1c08220(chbG)
SPE: Spro_0838
SRL: SOD_c07050(chbG)
SPLY: Q5A_003675(chbG)
SERF: L085_00150
SQU: E4343_12365(chbG)
SURI: J0X03_19905(chbG)
RAA: Q7S_23761
RACE: JHW33_23515(chbG)
EAME: GXP68_18095(chbG)
PMR: PMI2951(chbG)
PHAU: PH4a_06305
PCOL: F1325_18325(chbG)
PCIB: F9282_18900(chbG)
PSI: S70_15160
PSX: DR96_265
PRQ: CYG50_20885(chbG)
PVC: G3341_15470(chbG)
DCS: ISN74_17620(hpnK)
VSC: VSVS12_02688(chbG)
VFI: VF_1341(chbG)
PPR: PBPRA0494(VC1280) PBPRA0498
PGH: FH974_13500(chbG)
PFL: PFL_3093
PPRO: PPC_3121
PMAN: OU5_5825
PKC: PKB_2739
PSOS: POS17_3097
PDW: BV82_5084
SBL: Sbal_1411
SWD: Swoo_0564
CBU: CBU_0580
CBD: CBUD_1482
CBG: CbuG_1418
CBC: CbuK_1258
ALG: AQULUS_13570(chbG)
LPN: lpg2480
LPH: LPV_2804
LPO: LPO_2669
LPM: LP6_2510
LPF: lpl2400
LPP: lpp2544
LPC: LPC_1998
LPA: lpa_03611
LPE: lp12_2472
LLO: LLO_3054
LFA: LFA_3342
TMC: LMI_2081
FTQ: RO31_0513
FTF: FTF0453c
FTW: FTW_1617
FTT: FTV_0420
FTG: FTU_0504
FTL: FTL_1612
FTH: FTH_1559
FTA: FTA_1700
FTS: F92_08920
FTI: FTS_1573
FTC: DA46_1134
FTV: CH67_2014
FTZ: CH68_1745
FTM: FTM_1450
FTN: FTN_0544
FTX: AW25_1485
FTD: AS84_134
FTY: CH70_1515
FPH: Fphi_0293
FPT: BZ13_1777
FPI: BF30_468
FPM: LA56_21
FPX: KU46_1084
FPZ: LA55_548
FPJ: LA02_1905
NTT: TAO_1018
AVR: B565_2907
AALL: I6G90_00465(chbG)
SALN: SALB1_0326
LHK: LHK_01292
PSE: NH8B_1025
AMAH: DLM_0369
REH: H16_B2173(h16_B2173)
BPSE: BDL_3092
BPSD: BBX_1493
BPSO: X996_1767
BTD: BTI_1236
BOK: DM82_2011
BOC: BG90_2701
BVE: AK36_2756
BCJ: BCAL1052
BCEW: DM40_1837
BCEO: I35_1044
BMJ: BMULJ_01112(ydjC)
BMU: Bmul_2132
BMK: DM80_465
BMUL: NP80_1278
BCT: GEM_2341
BCED: DM42_550
BLAT: WK25_05590
BTEI: WS51_16130
BSEM: WJ12_05755
BMEC: WJ16_05530
BSTG: WT74_05885
BYI: BYI23_A022800(hpnK)
BUK: MYA_1070
BUE: BRPE67_ACDS23560(hpnK)
BUL: BW21_1385
BXB: DR64_4224
BFN: OI25_3726
PTRO: G5S35_09065(hpnK)
PACP: FAZ97_08600(hpnK)
PACS: FAZ98_08495(hpnK)
BAV: BAV2925
BHO: D560_2108
BHM: D558_2083
AMIM: MIM_c28640
BPSI: IX83_00515
RFR: Rfer_0768
DAC: Daci_0563
CTES: O987_02180
HAR: HEAR2594
MMS: mma_2832
RGE: RGE_31760
BBAG: E1O_04530
MFA: Mfla_1375
MMB: Mmol_1242
MEP: MPQ_1356
ABRE: pbN1_11770
APET: ToN1_31730
DAR: Daro_2756
AZO: azo0748
AOA: dqs_0822
AZA: AZKH_0686
GSK: KN400_1128(hpnK)
GME: Gmet_2415(hpnK)
GUR: Gura_2962
GLO: Glov_3091
GEO: Geob_2290(hpnK)
GEM: GM21_3381
GEB: GM18_0768
GBM: Gbem_0879(hpnK)
GBN: GEOBRER4_32550(hpnK)
GER: KP004_15895(hpnK)
PPD: Ppro_2826
DMA: DMR_20950
DGG: DGI_1411
DAS: Daes_0010
DPI: BN4_12222
DSF: UWK_01990
DAL: Dalk_4316
ADE: Adeh_1624
MXA: MXAN_6314
CCX: COCOR_06930(ydjC1)
MLO: mll3087
MHUA: MCHK_4586
AVI: Avi_1930
KAI: K32_29350
BJA: blr7527(blr7527)
BRA: BRADO6109
BBT: BBta_1678
BRS: S23_61570
AOL: S58_62960
BRAD: BF49_3060
BARH: WN72_42785
RPA: RPA1147
RPB: RPB_1843
RPC: RPC_4720
RPD: RPD_4120
RPE: RPE_0869
RPT: Rpal_1338
NWI: Nwi_2568
NHA: Nham_3190
OCA: OCAR_7265
XAU: Xaut_2351
AZC: AZC_1473
SNO: Snov_4401
MEX: Mext_3456
MPO: Mpop_3655
MET: M446_5304
MNO: Mnod_5902
META: Y590_16975
BID: Bind_1647
MSL: Msil_0374
HDN: Hden_0489
RVA: Rvan_0768
BVR: BVIR_2711
PSF: PSE_2365
RMM: ROSMUCSMR3_02843(chbG)
ZMO: ZMO0974
ZMN: Za10_0327
ZMM: Zmob_0332
ZMB: ZZ6_0332
ZMI: ZCP4_0342
SPHD: HY78_29080
STAX: MC45_05350
GOX: GOX0613
GOH: B932_0706
GOY: GLS_c07040(hpnK)
GSP: IGS75_03720(hpnK)
ACR: Acry_1837
GDI: GDI0717
GDJ: Gdia_1293
GXY: GLX_13950
GXL: H845_2662
KEU: S101446_01974(chbG)
KRE: GWK63_13065(hpnK)
KHA: IFJ82_03660(hpnK)
ASZ: ASN_2053
ABG: Asbog_00207(hpnK)
COMM: GN303_07640(hpnK)
BOB: GN304_07465(hpnK)
BOMB: GT348_01355(hpnK)
EBLA: JGUZn3_06100(chbG)
LCK: HN018_02120(hpnK)
RCE: RC1_0150
MGRY: MSR1_39560
AFR: AFE_2119
ACU: Atc_2235
HTL: HPTL_0038
BSON: S101395_04764(chbG)
BAN: BA_5440
BAR: GBAA_5440
BAT: BAS5055
BAI: BAA_5468
BANT: A16_54530
BANR: A16R_55160
BANS: BAPAT_5217
BANV: DJ46_4099
BCE: BC5208
BCA: BCE_5317
BCZ: BCE33L4900(celC)
BCQ: BCQ_5030(celC)
BCX: BCA_5336
BNC: BCN_5123
BCF: bcf_26045
BCER: BCK_09360
BTL: BALH_4700
BTT: HD73_5610
BTHI: BTK_27575
BTM: MC28_4440
BTI: BTG_22365
BTW: BF38_933
BWW: bwei_4586(celC)
BMYO: BG05_842
BMYC: DJ92_2259
BTRO: FJR70_20155(chbG)
BGY: BGLY_0274
BBEV: BBEV_3098(ydjC)
BHA: BH0913
CGOT: J1899_11435(chbG)
OIH: OB2271
OCB: CV093_18220(chbG)
ACAI: ISX45_04095(chbG)
TAID: KS242_04380(chbG)
VPT: KBP50_14875(chbG) KBP50_19630(chbG)
PPSR: I6J18_03230(chbG)
AQT: FN924_01375(chbG)
BVQ: FHE72_21130(chbG)
BSE: Bsel_0181
MLEN: H3V22_07730(chbG)
MVT: I6J10_10145(chbG)
LMO: lmo0191
LMOE: BN418_0200
LMOB: BN419_0204
LMOD: LMON_0189
LMOW: AX10_09410
LMOM: IJ09_09410
LMP: MUO_01100
LMOZ: LM1816_04582(chbG)
LMOX: AX24_13560
LMQ: LMM7_0212
LMS: LMLG_2394
LMOK: CQ02_01025
LMV: Y193_00265(chbG)
LWE: lwe0160
LSG: lse_0168
BLR: BRLA_c031950(hpnK)
BRW: GOP56_08095(chbG)
PSWU: SY83_09930
KEB: GXN75_02185(chbG)
SGT: SGGB_1619(ydjC)
STB: SGPB_1468
LAD: LA14_1470
LRL: LC705_00457(celC)
LRA: LRHK_470
LPJ: JDM1_0738
LPZ: Lp16_0707
PPE: PEPE_0080
LSA: LCA_1197
EFA: EF3048
EFQ: DR75_1773
ENE: ENT_27960
EFM: M7W_1485
ECAS: ECBG_01659
JDA: BW727_101382(chbG)
CBE: Cbei_4037
CBZ: Cbs_4037
CBEI: LF65_04544
CDY: F3K33_20660(chbG)
AMT: Amet_4184
BHU: bhn_I0555
CDF: CD630_28810(celG)
ROC: HF520_05935(chbG)
STH: STH2449
SWO: Swol_2271
DAE: Dtox_2008
DAU: Daud_1261
CTHM: CFE_0783
TTE: TTE0334
THX: Thet_0305
TOC: Toce_0341
VNK: VEIT17_09330(hpnK)
MED: MELS_0955
DHO: Dia5BBH33_09690(hpnK)
PUF: UFO1_2226
PFT: JBW_02366
STED: SPTER_16740(chbG)
AIN: Acin_1427
LCG: L3BBH23_02160(celG)
SMAL: SMALA_1974
SFA: Sfla_0362
SBH: SBI_02868
STRP: F750_6647
ACIT: HPK19_15835(chbG) HPK19_21170(chbG)
BCV: Bcav_3150
ACIJ: JS278_00342(chbG)
NML: Namu_4402
PSEA: WY02_15370
KAL: KALB_5779
AFO: Afer_1607
SYND: KR52_01695
SYW: SYNW0168
AMR: AM1_5796
ANB: ANA_C13135(hpnK)
DOU: BMF77_03713(chbG)
DFS: HGD76_23300(hpnK)
AFLO: HEQ12_08690(hpnK)
TOQ: HCG51_05035(hpnK)
RCA: Rcas_1066
ATM: ANT_22350
TTR: Tter_2373
DFC: DFI_08730
FTJ: FTUN_3641
ACA: ACP_0759
ABAS: ACPOL_1214
SUS: Acid_0579
GBA: J421_0636
PSAC: PSM36_0029
RMR: Rmar_2484
MUC: MuYL_1607
CHU: CHU_3769
LBY: Lbys_3372
HSW: Hsw_0822
FJO: Fjoh_0046
IAL: IALB_0194
SALI: L593_00615
 » show all
Reference
1  [PMID:17334758]
  Authors
Kadokura K, Rokutani A, Yamamoto M, Ikegami T, Sugita H, Itoi S, Hakamata W, Oku T, Nishio T
  Title
Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin.
  Journal
Appl Microbiol Biotechnol 75:357-65 (2007)
DOI:10.1007/s00253-006-0831-6
Reference
2  [PMID:19553519]
  Authors
Hirano T, Kadokura K, Ikegami T, Shigeta Y, Kumaki Y, Hakamata W, Oku T, Nishio T
  Title
Heterodisaccharide 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes.
  Journal
Glycobiology 19:1046-53 (2009)
DOI:10.1093/glycob/cwp088
  Sequence
Reference
3
  Authors
Ohishi, K., Yamagishi, M., Ohta, T., Motosugi, M., Izumida, H., Sano, H., Adachi, K., Miwa, T.
  Title
Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8.
  Journal
Biosci Biotechnol Biochem 61:1113-1117 (1997)
Reference
4  [PMID:16232910]
  Authors
Ohishi K, Murase K, Ohta T, Etoh H
  Title
Cloning and sequencing of the deacetylase gene from Vibrio alginolyticus H-8.
  Journal
J Biosci Bioeng 90:561-3 (2000)
DOI:10.1016/S1389-1723(01)80041-4
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.105
IUBMB Enzyme Nomenclature: 3.5.1.105
ExPASy - ENZYME nomenclature database: 3.5.1.105
BRENDA, the Enzyme Database: 3.5.1.105

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