KEGG   ENZYME: 3.5.1.105
Entry
EC 3.5.1.105                Enzyme                                 
Name
chitin disaccharide deacetylase;
chitobiose amidohydolase;
COD;
chitin oligosaccharide deacetylase;
chitin oligosaccharide amidohydolase;
2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
N,N'-diacetylchitobiose acetylhydrolase
Reaction(IUBMB)
N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate [RN:R11889]
Reaction(KEGG)
R11889
Substrate
N,N'-diacetylchitobiose [CPD:C01674];
H2O [CPD:C00001]
Product
N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine [CPD:C21747];
acetate [CPD:C00033]
Comment
Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains. Besides being a nutrient, the heterodisaccharide product 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus [2]. In contrast to EC 3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide [1,3]. It also deacetylates the chitin trisaccharide with lower efficiency [3]. No activity with higher polymers of GlcNAc [1,3].
History
EC 3.5.1.105 created 2010
Orthology
K03478  chitin disaccharide deacetylase
K18454  chitin disaccharide deacetylase
Genes
ECOb1733(chbG)
ECJJW1722(chbG)
ECDECDH10B_1871(chbG)
EBWBWG_1546(chbG)
ECOKECMDS42_1408(chbG)
ECEZ2763(ydjC)
ECSECs_2439(chbG)
ECFECH74115_2451
ETWECSP_2301(chbG)
ELXCDCO157_2273
EOIECO111_2244(chbG)
EOJECO26_2508(chbG)
EOHECO103_1926(chbG)
ECOOECRM13514_2230(ydjC)
ECOHECRM13516_2135(ydjC)
ESLO3K_11300
ESOO3O_14320
ESMO3M_11280
ECKEC55989_1901(chbG)
ECGE2348C_1861(chbG)
EOKG2583_2179(chbG)
ELRECO55CA74_10460
ELHETEC_1765
ECWEcE24377A_1954
EUNUMNK88_2197
ECPECP_1679
ENAECNA114_1778(ydjC)
ECOSEC958_1954(ydjC)
ECVAPECO1_802(ydjC)
ECOAAPECO78_12495
ECXEcHS_A1815
ECMEcSMS35_1458
ECYECSE_1903
ECRECIAI1_1793(chbG)
ECQECED1_1935(chbG)
EUMECUMN_2022(chbG)
ECTECIAI39_1321(chbG)
EBRECB_01702(ydjC)
EBLECD_01702(chbG)
EBEB21_01690(chbG)
EBDECBD_1912
ECIUTI89_C1926(ydjC)
EIHECOK1_1853
ECZECS88_1785(chbG)
ECCc2132(ydjC)
ELOEC042_1898(chbG)
ELNNRG857_08680
ESEECSF_1594
ECLEcolC_1899
EKOEKO11_2042
EKFKO11_14070
EABECABU_c19890(ydjC)
EDHEcDH1_1909
EDJECDH1ME8569_1677(chbG)
ELUUM146_08485
ELWECW_m1902(chbG)
ELLWFL_09325
ELCi14_1952(ydjC)
ELDi02_1952(ydjC)
ELPP12B_c1350
ELFLF82_0294(chbG)
ECOLLY180_09020
ECOIECOPMV1_01831
ECOJP423_09225
EFEEFER_1334(chbG)
EALEAKF1_ch0715c EAKF1_ch4318
EMAC1192_03630
ESZFEM44_18280(chbG) FEM44_23595(chbG)
STYSTY1796
STTt1196
SEXSTBHUCCB_12850
SENTTY21A_06080
STMSTM1317(celG)
SEOSTM14_1599(celG)
SEVSTMMW_13241
SEYSL1344_1252(celG)
SEMSTMDT12_C13340
SEJSTMUK_1284(celG)
SEBSTM474_1322(chbg)
SEFUMN798_1374
SETUSTU288_02910
SETCCFSAN001921_10570
SENRSTMDT2_12501
SENDDT104_12931
SENICY43_06705
SEENSE451236_12450
SPTSPA1527(celG)
SEKSSPA1418
SPQSPAB_02023
SEISPC_2413(celG)
SECSCH_1338(celG)
SEHSeHA_C1446
SHBSU5_01936
SENHCFSAN002069_02420
SEEHSEEH1578_15815
SEESNSL254_A1431
SENNSN31241_23920
SEWSeSA_A1414
SEASeAg_B1854
SENSQ786_08670
SEDSeD_A2027
SEGSG1799
SELSPUL_1134
SEGASPUCDC_1134
SETSEN1726
SENAAU38_08935
SENOAU37_08940
SENVAU39_08945
SENQAU40_09985
SENLIY59_09140
SENJCFSAN001992_05010
SEECCFSAN002050_12985
SEEBSEEB0189_012945
SEEPI137_05210
SENBBN855_13540
SENEIA1_06500
SENCSEET0819_13235
SESSARI_01661 SARI_02170
SBGSBG_1171
SBZA464_1272
SBVN643_05585
SALZEOS98_12880
SFLSF1495(ydjC)
SFXS1612(ydjC)
SFVSFV_1487(ydjC)
SFNSFy_2144
SFSSFyv_2196
SFTNCTC1_01612
SSNSSON_1425(ydjC)
SHQA0259_12720
ENCECL_02434
ENLA3UG_09090
ECLGEC036_17530
ECLEECNIH2_09700
ECLNECNIH4_13570
ECLIECNIH5_08770
ECLXLI66_09075
ECLYLI62_09850
ECLZLI64_09140
ECLOENC_14330
EHMAB284_15950
EXFBFV63_09110
ECLAECNIH3_08780
ECLCECR091_08755
EAUDI57_09815
EKBBFV64_09180
ENOECENHK_09085
EECEcWSU1_01795(ydjC)
ELGBH714_05315
ECANCWI88_13340
ERNBFV67_08630
ECLSLI67_010135
ECHGFY206_10485(chbG)
ESHC1N69_09230
ENTEnt638_1711
EASEntas_1729
ENRH650_10060
ENXNI40_009205
ENFAKI40_1012
LNICWR52_03100
EBGFAI37_20255(chbG)
ENDA4308_13775
ENZG0034_08900(chbG)
ENSHWQ15_17225(chbG)
ENKLOC22_19485(chbG)
EHUD5067_0013645(chbG)
EMORL6Y89_08770(chbG)
ENBELK40_09440
KPNKPN_01235(ydjC)
KPUKP1_2268
KPMKPHS_21350
KPPA79E_2951
KPHKPNIH24_17955
KPZKPNIH27_10380
KPVKPNIH29_10895
KPWKPNIH30_11140
KPYKPNIH31_10520
KPGKPNIH32_10980
KPCKPNIH10_10575
KPQKPR0928_10745
KPTVK055_1222
KPOKPN2242_09295
KPRKPR_2284
KPJN559_3045
KPID364_06400
KPAKPNJ1_03273
KPSKPNJ2_03264
KPXPMK1_03614
KPBFH42_02040
KPNEKU54_015520
KPNULI86_15830
KPNKBN49_2371
KVAKvar_3079
KPEKPK_3206
KPKA593_20905
KVDKR75_18750
KVQSP68_25195
KOXKOX_18220
KOEA225_2500
KOYJ415_19405
KOMHR38_16510
KMIVW41_07750
KOKKONIH1_12015
KOCAB185_23980
KQUAVR78_15570
EAEEAE_21530
EARCCG29631
KQVB8P98_16165
KLLBJF97_12565
KLWDA718_16410(chbG)
KARLGL98_14815(chbG)
KGRJJJ10_16305(chbG)
KPASLUW96_18590(chbG)
RORRORB6_08490
RONTE10_12300
RPLNB1209_15835
RAODSD31_15070
RTGNCTC13098_04195
REEelectrica_02996
CROROD_07511(chbG) ROD_13231(chbG)
CKOCKO_01758
CFDCFNIH1_16555
CBRAA6J81_02750
CWECO701_11690 CO701_15020
CYOCD187_13550
CPOTFOB25_01330(chbG)
CFQC2U38_13540
CSEDJY391_12240(chbG)
CAMAF384_05985
CAFAL524_16330
CIFAL515_10795
CFARCI104_11860
CIRC2U53_21060
CIEAN232_19310
CPARCUC49_06390
CTELGBC03_18725(chbG)
CITZE4Z61_03760(chbG)
CARSE1B03_11845(chbG)
CNTJT31_04660
CEMLH23_13345
CENLH86_12650
CLAPNCTC11466_02886
PGELG71_18365
ESCEntcl_2543
KLEAO703_09535
KSAC813_20515
KORAWR26_05150(chbG)
KRDA3780_18860
KPSEIP581_18370(chbG)
KOBHF650_19160(chbG)
KIENCTC12125_01650(chbF_1)
KASKATP_25780(chbG)
KLUK7B04_15630(chbG)
LAXAPT61_13105
LEIC2U54_14635
LEHC3F35_02135
LEEDVA44_14170
LERGNG29_09480(chbG)
LEAGNG26_09140(chbG)
LPNUKQ929_11715(chbG)
LAZA8A57_08965
LEFLJPFL01_1740
LEWDAI21_17680
BUFD8682_07125
BAGEBADSM9389_26530
BFTMNO13_16050(chbG)
METYMRY16398_22490(chbG)
YREHEC60_04235(chbG)
SGOEA8O29_013555(chbG)
KINAB182_10180
PDZHHA33_12790(chbG)
PSGCG163CM_15070(chbG)
EBFD782_2540
EBCC2U52_20755
EBUCUC76_04520
YPEYPO2682
YPKy1255
YPHYPC_3176
YPAYPA_2411
YPNYPN_1168
YPMYP_2484
YPPYPDSF_1592
YPGYpAngola_A3572(chbG)
YPZYPZ3_2366
YPTA1122_12665
YPDYPD4_2346
YPXYPD8_2345
YPWCH59_3562
YPJCH55_1489
YPVBZ15_851
YPLCH46_2427
YPSYPTB2927
YPOBZ17_3701
YPIYpsIP31758_1095(chbG)
YPYYPK_1148
YPBYPTS_3043
YPQDJ40_3562
YPUBZ21_2232
YPRBZ20_3245
YPCBZ23_2512
YPFBZ19_2298
YENYE0972
YEPYE105_C3110
YEYY11_42061
YEWCH47_375
YETCH48_630
YEFFORC2_0973
YSIBF17_01060
YALAT01_3453
YFRAW19_126
YINCH53_711
YKRCH54_1537
YROCH64_1564
YRUBD65_607
YRBUGYR_03260
YMADA391_05275
YHID5F51_16715
YCAF0T03_05380(chbG)
YMOHRD69_20405(chbG)
YASN0H69_08440(chbG)
YKIHRD70_09585(chbG)
SMARSM39_0157(chbG)
SMACSMDB11_0155(chbG)
SMWSMWW4_v1c08220(chbG)
SPESpro_0838
SRRSerAS9_0762
SRLSOD_c07050(chbG)
SRYM621_03815
SPLYQ5A_003675(chbG)
SRSSerAS12_0762
SRASerAS13_0762
SLQM495_03530
SERFL085_00150
SERSSERRSCBI_03820
SQUE4343_12365(chbG)
SFJSAMEA4384070_0872
SSURATE40_000755
SURIJ0X03_19905(chbG)
SENPKHA73_03750(chbG)
SNEMNLX84_03850(chbG)
RAHRahaq_4648
RACEJHW33_23515(chbG)
RAQRahaq2_4644
RAAQ7S_23761
RVCJ9880_22855(chbG)
EAMEGXP68_18095(chbG)
PMRPMI2951(chbG)
PMIBBB2000_2961
PVLAOB99_15990
PVGCRN77_04870
PHAUPH4a_06305
PROTBTA34_16100
PCOLF1325_18325(chbG)
PCIBF9282_18900(chbG)
PPEEI6G31_10405(chbG)
PSIS70_15160
PSXDR96_265
PSTABGK56_17950
PRGRB151_035220
PHEINCTC12003_03031
PRQCYG50_20885(chbG)
PVCG3341_15470(chbG)
PMAGJI723_15620(chbG)
HAVAT03_21380
OPODSM2777_04035
VCHVC_1280
VCFIR04_11700
VCSMS6_1061
VCEVch1786_I0784
VCQEN18_09690
VCJVCD_003070
VCIO3Y_05955
VCOVC0395_A0899
VCRVC395_1399
VCMVCM66_1235
VCLVCLMA_A1124
VCXVAA049_1513
VCZVAB027_1956
VVUVV1_1481
VVYVV2902
VVMVVMO6_00409
VVLVV93_v1c26080
VPAVP2638
VPBVPBB_2458
VPKM636_08635
VPFM634_15705
VPHVPUCM_2722
VHAVIBHAR_03626
VCAM892_13060
VAGN646_1731
VEXVEA_002434
VDBAL552_21990
VOWA9237_10560
VMIAL543_15755
VNLD3H41_14360
VPLSA104470976_01025
VTICEQ48_12325
PPRPBPRA0494(VC1280)
PSHHHU773_012320(chbG)
SBLSbal_1411
SBMShew185_1402
SBNSbal195_1438
SBPSbal223_2943
SBTSbal678_1473
SBSSbal117_1519
SBBSbal175_2925
SWDSwoo_0564
SHEWCKQ84_00710
AVRB565_2907
AEMCK911_11300
ARVC7N77_07040
AALLI6G90_00465(chbG)
ARIVKYK33_06250(chbG)
PGINFRZ67_03560
 » show all
Reference
1  [PMID:17334758]
  Authors
Kadokura K, Rokutani A, Yamamoto M, Ikegami T, Sugita H, Itoi S, Hakamata W, Oku T, Nishio T
  Title
Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin.
  Journal
Appl Microbiol Biotechnol 75:357-65 (2007)
DOI:10.1007/s00253-006-0831-6
Reference
2  [PMID:19553519]
  Authors
Hirano T, Kadokura K, Ikegami T, Shigeta Y, Kumaki Y, Hakamata W, Oku T, Nishio T
  Title
Heterodisaccharide 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes.
  Journal
Glycobiology 19:1046-53 (2009)
DOI:10.1093/glycob/cwp088
  Sequence
Reference
3
  Authors
Ohishi, K., Yamagishi, M., Ohta, T., Motosugi, M., Izumida, H., Sano, H., Adachi, K., Miwa, T.
  Title
Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8.
  Journal
Biosci Biotechnol Biochem 61:1113-1117 (1997)
Reference
4  [PMID:16232910]
  Authors
Ohishi K, Murase K, Ohta T, Etoh H
  Title
Cloning and sequencing of the deacetylase gene from Vibrio alginolyticus H-8.
  Journal
J Biosci Bioeng 90:561-3 (2000)
DOI:10.1016/S1389-1723(01)80041-4
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.105
IUBMB Enzyme Nomenclature: 3.5.1.105
ExPASy - ENZYME nomenclature database: 3.5.1.105
BRENDA, the Enzyme Database: 3.5.1.105

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