KEGG   ENZYME: 3.5.1.107
Entry
EC 3.5.1.107                Enzyme                                 
Name
maleamate amidohydrolase;
NicF
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
maleamate amidohydrolase
Reaction(IUBMB)
maleamate + H2O = maleate + NH3 [RN:R03540]
Reaction(KEGG)
R03540
Substrate
maleamate [CPD:C01596];
H2O [CPD:C00001]
Product
maleate [CPD:C01384];
NH3 [CPD:C00014]
Comment
The reaction is involved in the aerobic catabolism of nicotinic acid.
History
EC 3.5.1.107 created 2010
Pathway
ec00760  Nicotinate and nicotinamide metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K13995  maleamate amidohydrolase
Genes
SMARSM39_1767
SMACSMDB11_1580
SMWSMWW4_v1c23220
SPESpro_2308
SRRSerAS9_2265
SRLSOD_c21380(nicF)
SRYM621_11715
SPLYQ5A_011850(nicF)
SRSSerAS12_2265
SRASerAS13_2266
SLQM495_11485
SERFL085_17135
SQUE4343_04650
SFJSAMEA4384070_2377
SOFNCTC11214_04493
SURIJ0X03_12385
SNEMNLX84_11760
GQUAWC35_02990
BGJAWC36_12550
BRBEH207_04980
BNGEH206_16205
BIZHC231_17115
PAOPat9b_4746 Pat9b_5179
TCIA7K98_12075
STEKAXG53_18835
LCICINQ41_12765
LAVIINQ42_12395
DKOI596_2204
LRZBJI69_15095
PPUPP_3941(nicF)
PPFPput_1896
PPGPputGB1_3576
PPWPputW619_2143
PPTPPS_4057
PPBPPUBIRD1_1867
PPIYSA_08973
PPXT1E_5126
PPUTL483_21695
PPUNPP4_17810
PFSPFLU_2796
PFBVO64_0123
PAZOAYR47_21600
PMEDE3Z27_20700
PFWPF1751_v1c24670
PFFPFLUOLIPICF724395
PFXA7318_11845
PLULFOB45_03925
PSKU771_14840
PFZAV641_08710
PANRA7J50_2713
PSILPMA3_12550
PYMAK972_2671
PGGFX982_03126
PVKEPZ47_21840
PEZHWQ56_12815
PWYHU734_022640
PTAENCTC10697_01680
PPEGKUA23_13450
MADHP15_2601
AWUBEN71_18340
AGUAS4_40040
THTE2K93_08920 E2K93_09015
PATPatl_2732
ASPAOR13_567
ASQAVL57_15685
AAWAVL56_14640
ALEAV939_14590
ALZAV940_14340
GAGGlaag_1562
GNIGNIT_3185
PMESFX988_04157
OSGBST96_04575 BST96_08990
MICCAUP74_02905(nicF_1) AUP74_02925(nicF_2)
MAGAMag101_09770 Mag101_09855
MHYDGTQ55_10165 GTQ55_10270
HJABST95_09840
HALCEY643_08715 EY643_12885
AFUSEYZ66_05505
GAIIMCC3135_19300(nicF)
HAKKO116_00436
HAMHALO0540 HALO3993
HCOLOKO_02498(nicF_1) LOKO_03708(nicF_2)
HHHCLM76_08855
HVNEI420_01965
HOLHORIV_08620 HORIV_65100
HMDCTT34_03165
HAXIHAALTHF_14180n
HTTHZS52_01085 HZS52_07540
HCAMI4484_05230
HSVHNO53_05770
HTXEKK97_06055
HPROLMS44_02750 LMS44_20690
ADIB5T_02293
MFOIJSY38_15230
MARSA8C75_16315
MRZKDW95_18745
RFOREIFOR_02517(entB)
OCEGU3_07715 GU3_07735
RPJN234_04335 N234_24895
REHH16_A0926(h16_A0926) H16_B0814(h16_B0814)
CNCCNE_1c08760 CNE_2c07620
CUHBJN34_04915 BJN34_29415
REUReut_A2511 Reut_B3789
CTIRALTA_A0871
CBWRR42_s0172 RR42_s1173
CGDCR3_3006(nicF)
CCUPBKK81_07375
CUPBKK80_06675
CUUBKK79_05475
CPAUEHF44_27020
COXE0W60_08965 E0W60_14775
CCAMM5D45_06910
CCAXKZ686_20170
BOKDM82_729
BOCBG90_288
BSAVWS86_30285
BCMBcenmc03_3487
BCHBcen2424_4038
BCJBCAM1141
BCENDM39_3880
BCEOI35_4988
BAMBamb_4372
BACBamMC406_4889
BMUBmul_4551
BMKDM80_3721
BMULNP80_4068
BCEDDM42_3949
BCONNL30_06925
BSEMWJ12_25605
BPSLWS57_08420
BMECWJ16_24235
BSTGWT74_20820
BANNJFN94_22950 JFN94_25170
BARINLX30_32990 NLX30_38900
BGDbgla_1g12660
BGOBM43_2598
BYIBYI23_C007350 BYI23_C007830 BYI23_D006270 BYI23_D011210
BUEBRPE67_CCDS03400 BRPE67_CCDS04070 BRPE67_DCDS08090 BRPE67_DCDS13340
BGPBGL_1c11590
BPLAbpln_1g11110
BUMAXG89_36960
BUIAX768_15630
BURKDM992_20110
BXEBxe_C0217
BXBDR64_8214
BGEBC1002_4867
BPXBUPH_00081
BFNOI25_6798
BCAIK788_0007382
PTERC2L65_30580
PCAFDSC91_003181
PTROG5S35_31890
PACSFAZ98_30900
PSPUNA29_11635 NA29_13060
PVEUC34_12635
POXMB84_21145
PNRAT302_20400
PANDDRB87_17680
CABASBC2_37500(nicF_1) SBC2_53520(nicF_2) SBC2_77880
BUOBRPE64_CCDS01820 BRPE64_DCDS05950 BRPE64_DCDS11000
BPEBP0582 BP1958
BPCBPTD_0591 BPTD_1930
BPERBN118_0956 BN118_3485
BPETB1917_3472
BPEUQ425_15040 Q425_35670
BPARBN117_0270 BN117_1485 BN117_3524
BPABPP0272 BPP1128 BPP1414 BPP2331
BBHBN112_0305 BN112_1733 BN112_2115 BN112_3142
BBRBB0275 BB1344 BB1782 BB2483
BBMBN115_0260 BN115_1301 BN115_1684 BN115_2634
BBXBBS798_0270 BBS798_1306 BBS798_1683 BBS798_2319
BAVBAV0627 BAV1528 BAV2741
BHOD560_0263
BHMD558_0258
BHZACR54_00987(nicF)
BBROBAU06_10260 BAU06_12300 BAU06_14780 BAU06_25040
BFZBAU07_14185 BAU07_23490 BAU07_25075
BPDZBBN53_11420 BBN53_16860 BBN53_17715
BOHAKI39_11520 AKI39_14150
BGMCAL15_04735 CAL15_11465 CAL15_12485 CAL15_15585
AXYAXYL_02467 AXYL_05963 AXYL_06009
AXONH44784_051921
AXNAX27061_3328
AXXERS451415_03308
ADTAPT56_16405
AISBUW96_02615 BUW96_23530 BUW96_28745
ASWCVS48_09640
ACHRC2U31_23365
ACHBDVB37_25115
ADYHLG70_26540
ACHOH4P35_19050
PUSCKA81_13025
PUDG9Q38_03290 G9Q38_04185
AKATKWG_00620 TKWG_01110 TKWG_19785
AMIMMIM_c02060 MIM_c31070
CDNBN940_06141
AFAUZ73_09865 UZ73_10780 UZ73_14570 UZ73_14770
AFQAFA_00805 AFA_14960(nicF) AFA_15130(picF) AFA_18570(hpaF)
AAQUD3M96_15890 D3M96_16070
AAMMFE795_00740 FE795_13820 FE795_13995
PHNPAEH1_09745
ODIODI_R3899
BOZDBV39_01145 DBV39_15155 DBV39_16260 DBV39_18465
OUEI6G29_01845
PIGEGT29_02490 EGT29_02710 EGT29_02740 EGT29_03620 EGT29_05230 EGT29_09770 EGT29_10640 EGT29_17500
PACRFXN63_13575
PARKLSG25_13570 LSG25_16935
RHYRD110_10645 RD110_10650
AAVAave_3931
AAAAcav_3828
ACKC380_17110
VEIVeis_2915
DACDaci_1849
DELDelCs14_1768 DelCs14_4789
DTSBI380_15405
DHKBO996_08755
DLAI6G47_15035
VAPVapar_4294
VPEVarpa_0931
VAMC4F17_28030
CTESO987_23200
HYNF9K07_02955 F9K07_16570 F9K07_21895 F9K07_30515
HSEHsero_1326(entB)
HSZACP92_06635
HEEhmeg3_19270
HFRG5S34_06845
MTIMDIR46_21160
XYKGT347_17970
DOEDENOEST_2379 DENOEST_2426
APETToN1_50040 ToN1_50090
AZAAZKH_p0025
AZDCDA09_08595 CDA09_08620
AZRCJ010_22075
BEBAEM42_06380
BEBABWI17_00580
MLNA9174_30220 A9174_33970
MCIMesci_0837
MAMMesau_00845
MAMOA6B35_10465
MHUAMCHK_0587
MJREB229_30820
MERDEB233_04340 EB233_27025
MESOBSQ44_19935
HOEIMCC20628_03532
AAKAA2016_6396 AA2016_6585
NIYFQ775_08145
ORMHTY61_12055
SMKSinme_5996
SMDSmed_5107
RHINGR_b01900
SFHSFHH103_06750
EAKEKH55_4016
ATAAWN88_01315
AVIAvi_7125
ARUIG6M88_16300 G6M88_17770 G6M88_20635
AVQHRR99_16110 HRR99_16335
RLGRleg_6045
RTRRTCIAT899_PC08585
RJGCCGE525_26750 CCGE525_33260
RADCO657_35885
RIIFFM53_028510
RRGJ3P73_36850
RLSHB780_10725
RAWNE851_01765
RSULN2599_21420
NEOCYG48_16650
NENNCHU2750_54890
SHZshn_30280
KAIK32_41300
BJUBJ6T_15770
BJPRN69_07790
BRKCWS35_28860
BOTCIT37_06760
BGQX265_13540
BARHWN72_44290
BELBE61_17010
BQBJ4P68_0007720
RBKE0H22_02845
BOPAXW83_21105
BOSBSY19_2427 BSY19_2429
BVVBHK69_19725
LNEFZC33_05105
APRAG3A50_21590
METM446_4677
MNOMnod_7953
MAQUMaq22A_2p41510
METIDK427_04495
MINDmvi_23490
HMCHYPMC_0202
RHZRHPLAN_30750 RHPLAN_31080 RHPLAN_54050 RHPLAN_55350 RHPLAN_56180
PHLKKY_3789
DEIC4375_16585
DEAFPZ08_15170
HDIHDIA_0513
MMEDMame_05088(nicF_2)
AUBLXB15_07225
PSINCAK95_02120 CAK95_12380 CAK95_14170
NOHG5V57_02400
PPHRAPZ00_25435
SIWGH266_16075
CFHC1707_14880 C1707_20445
BNEDA69_03045
RLIRLO149_c007590
KVLKVU_1393
KVUEIO_1939
KROBVG79_00051
OAROA238_c08180
LMDMETH_16480
CIDP73_1976 P73_2829 P73_3891
CONTQ29_12575 TQ29_12805
YANAYJ57_04940 AYJ57_10105
TPROGa0080559_TMP3661
PABYGa0080574_TMP269 Ga0080574_TMP30 Ga0080574_TMP534
SULDB5M07_03980
ROKRAK1035_3616
RIDRIdsm_00915(nicF)
AHTANTHELSMS3_04601
SAGUCDO87_22445
THAACFI11_12330
MALUKU6B_06570
LSALKBK07_09915
PAMIJCM7686_1661
PYEA6J80_00025 A6J80_03050 A6J80_23195
PARUCYR75_10325
PSANHGN31_04695
DAAAKL17_3237
LVSLOKVESSMR4R_02439(nicF) LOKVESSMR4R_03231(nicF)
GEHHYN69_10295
PAEDG5B38_05370
PSHQF3W81_00320 F3W81_03060 F3W81_11585
HDHG5B40_14955 G5B40_18545
CMAGCBW24_04230
FAPGR316_10980
GAKX907_0754
HNEHNE_1116
HBAHbal_1508
HBCAEM38_11605
NARSaro_0173
NPPPP1Y_AT10443 PP1Y_AT10712 PP1Y_AT20042
NREBES08_19555 BES08_21970 BES08_22235 BES08_22305
NOVTQ38_023400 TQ38_023620 TQ38_025725
NOTC7W88_19010 C7W88_19205
NGFFRF71_10785 FRF71_11020
NOGGKE62_07545 GKE62_16175
NDRHT578_02000
SPHOC3E99_18820
SPHDHY78_17700
SPHMG432_00420
SPHITS85_14885 TS85_23125
SSANNX02_13740
SNJA7E77_04550
SMYBJP26_14905
SPANAWL63_15740
SPHAD3Y57_07685
SLANGV829_03670 GV829_06010
SSEDH9L14_04580
SPAPH3Z74_17875
SBARH5V43_17410 H5V43_21655(ndpG)
SPPHKFK14_05030
SPHGAZE99_12515 AZE99_12560 AZE99_14810
SFLASPHFLASMR4Y_02110(nicF) SPHFLASMR4Y_02608(nicF)
SPHYCHN51_04225 CHN51_07560
SPHLLPB140_01110
BLASBSY18_2243 BSY18_3112
BFWB5J99_02785 B5J99_05545
SPZRG5C33_02915
PALGHFP57_10345 HFP57_14175 HFP57_15950
PARJJ4G78_12915 J4G78_12965
SMICSmB9_17870
SANDH3309_09645 H3309_09930
POQKZX46_13160 KZX46_14015
PMEAKTC28_11215 KTC28_12180
ALHG6N82_04860 G6N82_07315
ANHA6F65_00059(nicF)
ADOA6F68_02624(nicF)
EGNBMF35_a1265
ELQGa0102493_11587 Ga0102493_11632
ERKCD351_07495
ERFFIU90_14360(nicF)
PORLBG023_112530
PHZCHX26_05960 CHX26_13875
POTE2E27_08220
GOYGLS_c14240
GALA0U94_10310
GTIFXF46_02570
GSPIGS75_12415
GDIGDI2694
GDJGdia_0908
GXLH845_1041
KEUS101446_01673(nicF)
KSCCD178_02877(nicF)
KREGWK63_12510
APTAPA01_23750
APWAPA42C_23750
APFAPA03_23750
APUAPA07_23750
APGAPA12_23750
APQAPA22_23750
APXAPA26_23750
APZAPA32_23750
APKAPA386B_1209
ASVWG31_11900
APOMCPF11_08780
ATOCIW82_09430
AASCA4S02_13835
ACETDS739_11630
RGIRGI145_12690 RGI145_14660
ROSCTJ15_21280
RMUCFOB66_16705
RMTIAI58_12645 IAI58_20215
NCHA0U93_15435
KHAIFJ82_11090
SRFLHU95_04835 LHU95_19615
SHUMSTHU_25060 STHU_55380
STELSTAQ_22590
ALIAZOLI_p20438
ABSAZOBR_p230065 AZOBR_p230071 AZOBR_p480012
ABQABAZ39_26740 ABAZ39_26770 ABAZ39_30175
ABFAMK58_24295 AMK58_24325 AMK58_25900
ATIAL072_18540 AL072_18570 AL072_30660
AZTTSH58p_02225 TSH58p_02255 TSH58p_19535
AZMDM194_20080 DM194_21865
AOZHUE56_08280
AARED3093_23760 D3093_23790 D3093_29335
NAOY958_30715
NCBC0V82_13835 C0V82_18220 C0V82_18420 C0V82_18480
SKTIGS68_05340
TMOTMO_a0287
HADHFRZ61_20850 FRZ61_46380
BFDNCTC4823_00523
PARHI5S86_12090
OCNCUC15_19425
OCBCV093_20960
GYCGYMC61_3600
GYAGYMC52_3626
TAPGZ22_02460
LAOAOX59_16885
PSABPSAB_06990
PDUPDUR_08060
PBJVN24_18340
PNPIJ22_19960
PCXLPB68_00125 LPB68_21335
PSOPKP014_10700
PLLI858_004560
PMARB0X71_17605
RUJE5Z56_09540
CBOLCGC65_18555
PSORRSJ16_02180
FWADCMF_20055 DCMF_20060 DCMF_22905
CCNH924_12915
CTERA606_01055
CCYCSCMU_09020
NOZDMB37_03000
NODFOH10_15780
NIEKV110_07870
NHUH0264_26075
NYALTV02_12160
ROAPd630_LPD07323
RBYCEJ39_09970
RAVAAT18_09665
RRZCS378_24500
RHUA3Q40_03847(nicF_2)
RHQIM25_13375
GBRGbro_2858
GRUGCWB2_00560(nicF)
GAVC5O27_04045
GODGKZ92_00900
GJIH1R19_19715
DIZCT688_06975
SVLStrvi_4761
SRCM271_44550
SMALSMALA_0620
SSOII1A49_06680
STREGZL_07757
SNRSNOUR_35440
SALUDC74_1458
SALLSAZ_07815
SAUOBV401_06930
SVUB1H20_22600
SCYAEJ357_22515
SBATG4Z16_05060 G4Z16_06590
SFEUIM697_01765
SGOBtest1122_09475
SINEKI385_04390
SDURM4V62_06945
LXLKDY119_00199(nicF)
MPALBO218_11365
MWAE4K62_15750
MSEDE3O41_13930
MICSC1N74_15660
CUBBJK06_11545
CPHYB5808_03745
HUMDVJ78_17185
LINSG7067_10835
LLUTK1X41_15055
HEHL3i23_27680
ARTArth_4359
AAQAOC05_01020
ARZAUT26_17210 AUT26_19550
ARXARZXY2_141
ACRYAC20117_22745
ARTYAHiyo4_45690
PUEFV140_18830 FV140_21300
APNAsphe3_40650 Asphe3_42510
GPRJQN66_17340
SATKSA2016_1125
NAEBHE16_06020 BHE16_07160
CIGE7744_00760
ICAIntca_1828
JMEEEW87_17250
ORZFNH13_08170
NOIFCL41_08920 FCL41_11060
NDPE2C04_09440
NMESH9L09_11040
AEZC3E78_17375
AEFGEV26_17130
MUZH4N58_12885
ACTWF7P10_38725
SROSros_6622
NCXNocox_12475(nicF2)
FALFRAAL6164
BSDBLASA_3399
MMARMODMU_4051
AMQAMETH_3943
AMYCCU254_15745
AMYYYIM_29090(nicF1)
PDXPsed_4155 Psed_4173 Psed_4639 Psed_4797 Psed_5044
PSEAWY02_01040 WY02_22140
PSEEFRP1_20550
PSEHXF36_05355
PSEQAD006_27970
PECQAD017_07565
PHHAFB00_17890
PAUTPdca_13700
PBROHOP40_05465 HOP40_34535
PPELH6H00_31575
APRECNX65_13315
AMIAmir_2624
KPHYAOZ06_12490
SACEGIY23_14765
MTUACSH63_04550
MICHFJK98_11805
MCRAID554_00490
VERHUT12_12500
AMSAMIS_57510
AFSAFR_17595
AIHAiant_14710
PSUUPsuf_074240
CATICS0771_62420
RXYRxyl_1694
RRDRradSPS_1618
RUBGBA63_03905
BSOLFSW04_01900 FSW04_08195 FSW04_13000
CWOCwoe_1059 Cwoe_3971 Cwoe_4343
AYMYM304_39650
EUZDVS28_a2592
RRSRoseRS_0048
STISthe_2930
LCREPla8534_61450
AAGGETAA8_33160
SLRL21SP2_3330
PPIOCE91St28_23690
CAGGHYG79_06715
HJEHacjB3_03150
NHOHWV23_05485
HGIABY42_17670
HALEG3A49_05940
HLAHlac_1098
HALPDOS48_11135
HEZZEO776_16390
HALQHrr1229_000845
HSSJ7656_11270
SRUBC2R22_10025 C2R22_14940
HDFAArcSl_1053(nicF)
NVRFEJ81_22610
NAGAArcMg_1969
NANAArc1_1711
NBGDV706_17725 DV706_21495
NASGCU68_04165 GCU68_19020
SACDHS1genome_0542
 » show all
Reference
1  [PMID:18678916]
  Authors
Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E
  Title
Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.
  Journal
Proc Natl Acad Sci U S A 105:11329-34 (2008)
DOI:10.1073/pnas.0802273105
  Sequence
[ppu:PP_3941]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.107
IUBMB Enzyme Nomenclature: 3.5.1.107
ExPASy - ENZYME nomenclature database: 3.5.1.107
BRENDA, the Enzyme Database: 3.5.1.107

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