KEGG   ENZYME: 3.5.1.110
Entry
EC 3.5.1.110                Enzyme                                 

Name
ureidoacrylate amidohydrolase;
peroxyureidoacrylate/ureidoacrylate amidohydrolase;
rutB (gene name);
(Z)-3-ureidoacrylate peracid amidohydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
(Z)-3-ureidoacrylate amidohydrolase
Reaction(IUBMB)
(1) (Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + CO2 + NH3 (overall reaction) [RN:R12625];
(1a) (Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + carbamate [RN:R09980];
(1b) carbamate = CO2 + NH3 (spontaneous) [RN:R07316];
(2) (Z)-2-methylureidoacrylate + H2O = (Z)-2-methylaminoacrylate + CO2 + NH3 (overall reaction) [RN:R12623];
(2a) (Z)-2-methylureidoacrylate + H2O = (Z)-2-methylaminoacrylate + carbamate [RN:R12624];
(2b) carbamate = CO2 + NH3 (spontaneous)
Reaction(KEGG)
Substrate
(Z)-3-ureidoacrylate [CPD:C20254];
H2O [CPD:C00001];
carbamate [CPD:C01563];
(Z)-2-methylureidoacrylate [CPD:C20256]
Product
(Z)-3-aminoacrylate [CPD:C20253];
CO2 [CPD:C00011];
NH3 [CPD:C00014];
carbamate [CPD:C01563];
(Z)-2-methylaminoacrylate [CPD:C20255]
Comment
The enzyme participates in the Rut pyrimidine catabolic pathway.
History
EC 3.5.1.110 created 2012, modified 2020
Pathway
ec00240  Pyrimidine metabolism
ec01100  Metabolic pathways
Orthology
K09020  ureidoacrylate peracid hydrolase
Genes
PXY: 105396809
ECO: b1011(rutB)
ECJ: JW5139(ycdL)
ECD: ECDH10B_1083(rutB)
EBW: BWG_0865(rutB)
ECOK: ECMDS42_0856(ycdL)
ECE: Z1510
ECS: ECs1257
ECF: ECH74115_1248
ETW: ECSP_1180
EOI: ECO111_1200(ycdL)
EOJ: ECO26_1249(ycdL)
EOH: ECO103_1057(ycdL)
ECOO: ECRM13514_1188(rutB)
ECOH: ECRM13516_1117(rutB)
ESL: O3K_15930
ESO: O3O_09365
ESM: O3M_15905
ECK: EC55989_1122(rutB)
ECG: E2348C_1062(rutB)
EOK: G2583_1244(rutB)
ECP: ECP_1010
ENA: ECNA114_1082(ycdL)
ECOS: EC958_1208(ycdL)
ECY: ECSE_1073
ECR: ECIAI1_1056(rutB)
ECQ: ECED1_1167(rutB)
EUM: ECUMN_1194(rutB)
ECT: ECIAI39_2144(rutB)
EOC: CE10_1089(rutB)
EBR: ECB_01014(ycdL)
EBL: ECD_01014(rutB)
EBE: B21_01021(rutB)
EBD: ECBD_2583
ECI: UTI89_C1074(ycdL)
ECZ: ECS88_1027(rutB)
ECC: c1148(ycdL)
ELO: EC042_1086(rutB)
ESE: ECSF_0917
EKF: KO11_17665(rutB)
EAB: ECABU_c10380(rutB)
EDJ: ECDH1ME8569_0965(rutB)
ELW: ECW_m1121(rutB)
ELL: WFL_05470(rutB)
ELC: i14_1048(ycdL)
ELD: i02_1048(ycdL)
ELP: P12B_c0996(ycdL)
ELF: LF82_2050(rutB)
ECOI: ECOPMV1_01033(rutB_1)
ECOJ: P423_05495
ESZ: FEM44_19935(rutB)
SFL: SF1014
SFX: S1084
SFV: SFV_1023
SFE: SFxv_1100(rutB)
SFN: SFy_1389
SFS: SFyv_1432
SFT: NCTC1_01053(rutB)
SSN: SSON_1030
ENC: ECL_02623(rutB)
ECLX: LI66_07885
ECLY: LI62_08675
ECLZ: LI64_08210
ECLO: ENC_16300
EEC: EcWSU1_01609(rutB)
ECHG: FY206_09410(rutB)
ESH: C1N69_08295(rutB)
EBG: FAI37_21410(rutB)
ESA: ESA_02363
CSK: ES15_2462(rutB)
CTU: CTU_15920(rutB)
KPN: KPN_01037(ycdL)
KPU: KP1_2025(ycdL)
KPP: A79E_3195
KPT: VK055_1440(rutB)
KPR: KPR_3486
KPJ: N559_3249
KPX: PMK1_03377(rutB)
KPNU: LI86_16885
KPNK: BN49_2126(rutB)
KVA: Kvar_3342
KPE: KPK_3521
KOX: KOX_16995
KOE: A225_2249
EAE: EAE_16030
EAR: CCG30701
KQV: B8P98_18065(rutB)
KLW: DA718_17560(rutB)
RAO: DSD31_16100(rutB)
RTG: NCTC13098_00839(rutB_1) NCTC13098_04744(rutB_2)
REE: electrica_03236(rutB)
LEI: C2U54_13135(rutB)
LEH: C3F35_03170(rutB)
LEE: DVA44_15425(rutB)
LER: GNG29_08305(rutB)
LEA: GNG26_07925(rutB)
LNI: CWR52_04070(rutB)
LEW: DAI21_18785(rutB)
BUF: D8682_07200(rutB)
METY: MRY16398_36480(rutB)
IZH: FEM41_12160(rutB)
PDZ: HHA33_18605(rutB)
EBC: C2U52_26765(rutB)
EBU: CUC76_06070(rutB)
PSTS: E05_37930
YEN: YE1949
YEY: Y11_13691
YEW: CH47_1381(rutB)
YET: CH48_3373(rutB)
YMA: DA391_09480(rutB)
SPE: Spro_1822
SRL: SOD_c16470(rutB)
SPLY: Q5A_009025(rutB_1)
SQU: E4343_07075(rutB)
SFJ: SAMEA4384070_1849(rutB_1)
RAA: Q7S_15220
EBI: EbC_15650(rutB) EbC_41610
EPE: CI789_10750(rutB)
ERWI: GN242_13270(rutB)
PAM: PANA_4034(ycdL)
PLF: PANA5342_p10176(rutB)
PAJ: PAJ_p0252(ycdL)
PAQ: PAGR_p121
PVA: Pvag_0804(ycdl1)
PAGG: AL522_11300(rutB)
PSTW: DSJ_25270
PEY: EE896_12570(rutB)
PDIS: D8B20_06585(rutB)
PGZ: C2E15_07955(rutB)
PCD: C2E16_07860(rutB)
PPSE: BN5_3190
PSB: Psyr_0998
PAMG: BKM19_007700(rutB)
PAVL: BKM03_06645(rutB)
PVD: CFBP1590__4359(rutB)
PSA: PST_3598
PSTT: CH92_21420
PLUL: FOB45_22255(rutB)
PSES: PSCI_0303
ACC: BDGL_002278(rutB)
ACI: ACIAD0028
ASJ: AsACE_CH00967(rutB)
ARJ: DOM24_07650(rutB)
ACUM: C9E88_009230(rutB)
AGU: AS4_29270(rutB)
AUG: URS_1157
ALW: FOB21_15245(rutB)
ATN: FM020_07955(rutB)
AMAL: I607_16320
AMAE: I876_16625
AMAO: I634_16575
AMAD: I636_16510
AMAI: I635_17255
AMAG: I533_16140
AMAC: MASE_16135
AAUS: EP12_19145
GPS: C427_0833
AVR: B565_0919
ACAV: VI35_05135
AEL: NCTC12917_01078(rutB)
PPNO: DA70_00565
PPNM: LV28_05750
PSPU: NA29_12025
PAPI: SG18_23995
PLG: NCTC10937_03398(rutB)
BPE: BP2971
BPC: BPTD_2939
BPER: BN118_2880
BPET: B1917_0863
BPEU: Q425_23860
BPA: BPP3892
BAV: BAV0955
AXX: ERS451415_00658(rutB)
LIH: L63ED372_02457(yecD)
MMS: mma_3561
XYK: GT347_11525(rutB)
MEP: MPQ_1004(pncA)
HOH: Hoch_3936
MES: Meso_2306
AMIH: CO731_05406(rutB)
PLA: Plav_0992
SMER: DU99_14315
ATU: Atu2499
ARA: Arad_7072
ATF: Ach5_23690(rutB)
AGR: AGROH133_08498(rutB)
AGC: BSY240_840(rutB)
ARO: B0909_00435(rutB)
AGT: EYD00_10555(rutB)
ALF: CFBP5473_19080(rutB)
RIR: BN877_I2580(rutB)
RPUS: CFBP5875_10890(rutB)
ROY: G3A56_13455(rutB)
NEN: NCHU2750_47460(rutB)
SHZ: shn_28850
AOL: S58_22050
RPB: RPB_3116
TRB: HB776_23755(rutB)
MEA: Mex_1p1663(rutB)
MDI: METDI2411(rutB)
MEX: Mext_1737
MCH: Mchl_2056
MPO: Mpop_1076
MET: M446_1936
MOR: MOC_1963(rutB)
META: Y590_08275
MAQU: Maq22A_c03675(pncA)
METI: DK427_02035(rutB)
MMES: MMSR116_30940(rutB)
BID: Bind_1386
MMED: Mame_04496(rutB_3)
RBM: TEF_15385
CCR: CC_2795
CAUF: CSW63_19480(rutB)
TSV: DSM104635_00525(rutB)
JAN: Jann_3766
RDE: RD1_1500
DSH: Dshi_0690(entB)
KVL: KVU_1873
KVU: EIO_2338
KRO: BVG79_02010(rutB)
RID: RIdsm_01308(rutB)
HML: HmaOT1_07745(rutB)
ROT: FIV09_03215(rutB)
MALU: KU6B_32100(rutB)
HNE: HNE_1257
ZMN: Za10_0519
ZMM: Zmob_0528
ZMB: ZZ6_0530
ZMI: ZCP4_0542
ZMC: A265_00535(rutB)
ZMR: A254_00535(rutB)
NOV: TQ38_014340(rutB)
SPHI: TS85_06045
SPHR: BSY17_3631(rutB)
SMIC: SmB9_20250(rutB)
SPZR: G5C33_08820(rutB)
AAY: WYH_00067(rutB_2)
GOH: B932_2840
NCB: C0V82_24840(rutB)
GEA: GARCT_p00014(rutB)
PRI: PRIO_2645
BTS: Btus_2001
ROB: CK5_32920
SAY: TPY_1338(rutB)
MIT: OCO_03210
MIA: OCU_03290
MIR: OCQ_03240
MJL: Mjls_4119
MMI: MMAR_3790
MMM: W7S_01580
MHAS: MHAS_03078(yecD_2)
NAD: NCTC11293_04762(rutB_2)
RER: RER_41020
REY: O5Y_19150
RRT: 4535765_03099(rutB)
RCR: NCTC10994_02345(rutB)
GOM: D7316_05163(rutB_2)
KFL: Kfla_2519
PSIM: KR76_24890
SRO: Sros_4718
FAL: FRAAL4263
MMAR: MODMU_1501
SEN: SACE_1113
PDX: Psed_2449
SESP: BN6_55700
KAL: KALB_1146
AFS: AFR_10510
CAI: Caci_8742
HAU: Haur_3125
STI: Sthe_2711
DFC: DFI_17400
ABAC: LuPra_02691(rutB_1)
RMR: Rmar_2385
SLI: Slin_0010
MAC: MA_4411
TAA: NMY3_00539(rutB_1) NMY3_01094(rutB_2) NMY3_02609(rutB_3)
NFN: NFRAN_0039(rutB) NFRAN_0219(rutB)
 » show all
Reference
1  [PMID:20400551]
  Authors
Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer DE
  Title
The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems.
  Journal
J Bacteriol 192:4089-102 (2010)
DOI:10.1128/JB.00201-10
  Sequence
[eco:b1011]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.110
IUBMB Enzyme Nomenclature: 3.5.1.110
ExPASy - ENZYME nomenclature database: 3.5.1.110
BRENDA, the Enzyme Database: 3.5.1.110

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