KEGG   ENZYME: 3.5.1.116Help
Entry
EC 3.5.1.116                Enzyme                                 

Name
ureidoglycolate amidohydrolase;
ureidoglycolate hydrolase;
UAH (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
(S)-ureidoglycolate amidohydrolase (decarboxylating)
Reaction(IUBMB)
(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2 [RN:R00469]
Reaction(KEGG)
Substrate
(S)-ureidoglycolate [CPD:C00603];
H2O [CPD:C00001]
Product
glyoxylate [CPD:C00048];
NH3 [CPD:C00014];
CO2 [CPD:C00011]
Comment
This plant enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 4.3.2.3, ureidoglycolate lyase, which releases urea rather than ammonia.
History
EC 3.5.1.116 created 1992 as EC 3.5.3.19, transferred 2014 to EC 3.5.1.116
Pathway
ec00230  Purine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18151  ureidoglycolate amidohydrolase
Genes
ATH: AT5G43600(UAH)
CRB: 17877004
CSAT: 104725100 104760596 104771509
EUS: EUTSA_v10003195mg
BRP: 103827965
BNA: 106411035 111213038
BOE: 106301296 106303989
RSZ: 108848496 108849401
THJ: 104801094
CPAP: 110814033
CIT: 102621156
TCC: 18603136
GRA: 105798789
GAB: 108457237
EGR: 104414568
GMX: 100797579
VRA: 106772682
VAR: 108324130
VUN: 114192461
CCAJ: 109800918
CAM: 101497175
LJA: Lj5g3v1174280.1(Lj5g3v1174280.1) Lj5g3v1174280.2(Lj5g3v1174280.2)
ADU: 107466267
AIP: 107618184
FVE: 101301243
PPER: 18789197
PMUM: 103324157
PAVI: 110745978
MDM: 103414713
PXB: 103939434
ZJU: 107422837
CSV: 101216373
CMO: 103483639
MCHA: 111016352
CMAX: 111474417
CMOS: 111450481
CPEP: 111800783
RCU: 8280165
JCU: 105632097
HBR: 110673262
MESC: 110612063
POP: 7498032
PEU: 105129965
JRE: 108985520
QSU: 112033150
VVI: 100261431
SLY: 101246378
SPEN: 107029269
NSY: 104249923
NTO: 104119778
NAU: 109217611
INI: 109175839
SIND: 105171654
OEU: 111383584
HAN: 110896191
LSV: 111897274
CCAV: 112519037
DCR: 108197102
BVG: 104888752
SOE: 110782326
NNU: 104612407
PSOM: 113349981
OSA: 4352706
DOSA: Os12t0597500-01(Os12g0597500)
OBR: 102704859
ATS: 109745371(LOC109745371)
SBI: 8076633
ZMA: 100279195
SITA: 101760265
PDA: 103724144
EGU: 105053076
MUS: 104000367
DCT: 114581104
PEQ: 110023307
AOF: 109848756
ATR: 18429484
PPP: 112286677
APRO: F751_5617
TRA: Trad_1507
MRB: Mrub_1386
MIN: Minf_2338(argE)
ABAS: ACPOL_2454
SUS: Acid_0364
 » show all
Taxonomy
Reference
1  [PMID:16666035]
  Authors
Winkler RG, Blevins DG, Randall DD.
  Title
Ureide Catabolism in Soybeans : III. Ureidoglycolate Amidohydrolase and Allantoate Amidohydrolase Are Activities of an Allantoate Degrading Enzyme Complex.
  Journal
Plant Physiol 86:1084-1088 (1988)
Reference
2  [PMID:1910298]
  Authors
Wells XE, Lees EM
  Title
Ureidoglycolate amidohydrolase from developing French bean fruits (Phaseolus vulgaris [L.].).
  Journal
Arch Biochem Biophys 287:151-9 (1991)
DOI:10.1016/0003-9861(91)90400-D
Reference
3  [PMID:19935661]
  Authors
Werner AK, Romeis T, Witte CP
  Title
Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
  Journal
Nat Chem Biol 6:19-21 (2010)
DOI:10.1038/nchembio.265
  Sequence
[ath:AT5G43600]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.116
IUBMB Enzyme Nomenclature: 3.5.1.116
ExPASy - ENZYME nomenclature database: 3.5.1.116
BRENDA, the Enzyme Database: 3.5.1.116
CAS: 115629-07-7

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