KEGG   ENZYME: 3.5.1.116
Entry
EC 3.5.1.116                Enzyme                                 
Name
ureidoglycolate amidohydrolase;
ureidoglycolate hydrolase;
UAH (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
(S)-ureidoglycolate amidohydrolase (decarboxylating)
Reaction(IUBMB)
(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2 [RN:R00469]
Reaction(KEGG)
R00469
Substrate
(S)-ureidoglycolate [CPD:C00603];
H2O [CPD:C00001]
Product
glyoxylate [CPD:C00048];
NH3 [CPD:C00014];
CO2 [CPD:C00011]
Comment
This plant enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 4.3.2.3, ureidoglycolate lyase, which releases urea rather than ammonia.
History
EC 3.5.1.116 created 1992 as EC 3.5.3.19, transferred 2014 to EC 3.5.1.116
Pathway
ec00230  Purine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18151  ureidoglycolate amidohydrolase
Genes
ATHAT5G43600(UAH)
ALY9301486
CRB17877004
CSAT104725100 104760596 104771509
EUSEUTSA_v10003195mg
BRP103827965
BNA106411035 111213038
BOE106301296
RSZ108848496 108849401
THJ104801094
CPAP110814033
CIT102621156
CICCICLE_v10004873mg CICLE_v10004875mg CICLE_v10007151mg
PVY116130886
MINC123211688
TCC18603136
GRA105798789
GHI107888887 107891907
GAB108457237
DZI111280126 111307373
EGR104414568
GMX100797579
GSJ114371959
PVUPHAVU_007G125700g
VRA106772682
VAR108324130
VUN114192461
CCAJ109800918
APRC113871156
MTRMTR_1g075320
CAM101497175
LJALj5g3v1174280.1(Lj5g3v1174280.1) Lj5g3v1174280.2(Lj5g3v1174280.2)
ADU107466267
AIP107618184
AHF112711255 112776056
LANG109339698 109359038
FVE101301243
RCN112196053 112199002
PPER18789197
PMUM103324157
PAVI110745978
PDUL117637071
MDM103414713
PXB103939434
ZJU107422837
MNT21399412
CSV101216373
CMO103483639
BHJ120069482
MCHA111016352
CMAX111474417
CMOS111450481
CPEP111800783
RCU8280165
JCU105632097
HBR110673262
MESC110612063
POP7498032
PEU105129965
PALZ118061545
JRE108985520
QSU112033150
QLO115995431
TWL120015476
VVI100261431
VRI117914894
SLY101246378
SPEN107029269
CANN107864617
NTA107770650 107818658
NSY104249923
NTO104119778
NAU109217611
INI109175839
ITR116002133
SIND105171654
OEU111383584
EGT105963025
SSPL121777564
HAN110896191
ECAD122606297
LSV111897274
CCAV112519037
DCR108197102
CSIN114266404
BVG104888752
SOE110782326
CQI110689320 110717654
NNU104612407
MING122066950
TSS122665397
PSOM113349981
NCOL116256185
OSA4352706
DOSAOs12t0597500-01(Os12g0597500)
OBR102704859
BDI100832540 100836497
ATS109745371
TDC119299328 119307523
TAES123102323 123110500 123119505
TUA125507931
SBI8076633
ZMA100279195
SITA101760265
SVS117850166
PVIR120666827 120700025
PHAI112886869
PDA103724144
EGU105053076
MUS104000367
DCT114581104
PEQ110023307
AOF109848756
ATR18429484
SMOSELMODRAFT_114863 SELMODRAFT_80479
PPP112286677
CRECHLRE_06g276700v5
VCNVOLCADRAFT_55680
CSLCOCSUDRAFT_26081 COCSUDRAFT_52944
CVRCHLNCDRAFT_140072
APROF751_5617
BPGBathy06g02260
MISMICPUN_93279
GSLGasu_35840
CCPCHC_T00000417001
SAMYDB32_006565
CBUTATN24_19535
LACYA4V08_32520
TRATrad_1507
MRBMrub_1386
MREK649_06590
MSVMesil_1787
MTAIMtai_v1c15880
LUOHHL09_09805
MINMinf_2338(argE)
MEAPMTHMO_0399(argE)
AAGGETAA8_33790(amaB)
LPAVPLANPX_2075
PNDPla175_41570(amaB_1)
PHMPSMK_30620
TPXTurpa_1298
ACMAciX9_2875
GMAAciX8_0717
GRWFTO74_13560
TSAAciPR4_3482
TRSTerro_0861
TALBFTW19_00730
ABASACPOL_2454
SUSAcid_0364
ABACLuPra_02258
 » show all
Reference
1  [PMID:16666035]
  Authors
Winkler RG, Blevins DG, Randall DD.
  Title
Ureide Catabolism in Soybeans : III. Ureidoglycolate Amidohydrolase and Allantoate Amidohydrolase Are Activities of an Allantoate Degrading Enzyme Complex.
  Journal
Plant Physiol 86:1084-1088 (1988)
DOI:10.1104/pp.86.4.1084
Reference
2  [PMID:1910298]
  Authors
Wells XE, Lees EM
  Title
Ureidoglycolate amidohydrolase from developing French bean fruits (Phaseolus vulgaris [L.].).
  Journal
Arch Biochem Biophys 287:151-9 (1991)
DOI:10.1016/0003-9861(91)90400-D
Reference
3  [PMID:19935661]
  Authors
Werner AK, Romeis T, Witte CP
  Title
Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
  Journal
Nat Chem Biol 6:19-21 (2010)
DOI:10.1038/nchembio.265
  Sequence
[ath:AT5G43600]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.116
IUBMB Enzyme Nomenclature: 3.5.1.116
ExPASy - ENZYME nomenclature database: 3.5.1.116
BRENDA, the Enzyme Database: 3.5.1.116
CAS: 115629-07-7

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