KEGG   ENZYME: 3.5.1.127
Entry
EC 3.5.1.127                Enzyme                                 

Name
jasmonoyl-L-amino acid hydrolase;
IAR3 (gene name);
ILL4 (gene name);
ILL6 (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
jasmonoyl-L amino acid amidohydrolase
Reaction(IUBMB)
a jasmonoyl-L-amino acid + H2O = jasmonate + an L-amino acid [RN:R11622]
Reaction(KEGG)
R11622
Substrate
jasmonoyl-L-amino acid [CPD:C21509];
H2O [CPD:C00001]
Product
jasmonate [CPD:C08491];
L-amino acid [CPD:C00151]
Comment
This entry includes a family of enzymes that recyle jasmonoyl-amino acid conjugates back to jasmonates. The enzymes from Arabidopsis thaliana have been shown to also act on 12-hydroxyjasmonoyl-L-isoleucine, generating tuberonic acid.
History
EC 3.5.1.127 created 2017
Orthology
K21604  jasmonoyl-L-amino acid hydrolase
Genes
ATH: AT1G44350(ILL6) AT1G51760(IAR3)
ALY: 9327351 9327722
CRB: 17896663 17897097
CSAT: 104742168 104742693 104757950 104758497 104758498 104777567 104778092
EUS: EUTSA_v10011458mg EUTSA_v10011481mg
BRP: 103847720 103868548
BNA: 106346506 106367115 106416276 106451636
BOE: 106296853 106296864 106300878
RSZ: 108805117 108809820 108845113
THJ: 104807029 104808247 104810558
VRA: 106762726
VAR: 108331929
LJA: Lj1g3v0841430.1(Lj1g3v0841430.1)
PXB: 103930518
DOSA: Os01t0560000-01(Os01g0560000) Os06t0691400-01(Os06g0691400)
ATS: 109752627(LOC109752627) 109769911(LOC109769911)
ATR: 18443675
 » show all
Reference
1  [PMID:24052260]
  Authors
Widemann E, Miesch L, Lugan R, Holder E, Heinrich C, Aubert Y, Miesch M, Pinot F, Heitz T
  Title
The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves.
  Journal
J Biol Chem 288:31701-14 (2013)
DOI:10.1074/jbc.M113.499228
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.127
IUBMB Enzyme Nomenclature: 3.5.1.127
ExPASy - ENZYME nomenclature database: 3.5.1.127
BRENDA, the Enzyme Database: 3.5.1.127

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