KEGG   ENZYME: 3.5.1.56
Entry
EC 3.5.1.56                 Enzyme                                 

Name
N,N-dimethylformamidase;
dimethylformamidase;
DMFase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
N,N-dimethylformamide amidohydrolase
Reaction(IUBMB)
N,N-dimethylformamide + H2O = dimethylamine + formate [RN:R02509]
Reaction(KEGG)
R02509
Substrate
N,N-dimethylformamide [CPD:C03134];
H2O [CPD:C00001]
Product
dimethylamine [CPD:C00543];
formate [CPD:C00058]
Comment
An iron protein. Also acts on N-ethylformamide and N-methyl-formamide and, more slowly, on N,N-diethylformamide, N,N-dimethylacetamide and unsubstituted acyl amides.
History
EC 3.5.1.56 created 1989
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
Orthology
K03418  N,N-dimethylformamidase large subunit
K25305  N,N-dimethylformamidase small subunit
Genes
METD: C0214_26885
PAMN: JCM7685_0286(dmfA1)
Reference
1  [PMID:3732281]
  Authors
Schar HP, Holzmann W, Ramos Tombo GM, Ghisalba O.
  Title
Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3.
  Journal
Eur J Biochem 158:469-75 (1986)
DOI:10.1111/j.1432-1033.1986.tb09778.x
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.56
IUBMB Enzyme Nomenclature: 3.5.1.56
ExPASy - ENZYME nomenclature database: 3.5.1.56
BRENDA, the Enzyme Database: 3.5.1.56
CAS: 104645-73-0

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