KEGG ENZYME: 3.5.1.58

ENZYME: 3.5.1.58

Entry

EC 3.5.1.58                 Enzyme

Name

N-benzyloxycarbonylglycine hydrolase;
benzyloxycarbonylglycine hydrolase;
Nalpha-carbobenzoxyamino acid amidohydrolase;
Nalpha-benzyloxycarbonyl amino acid urethane hydrolase;
Nalpha-benzyloxycarbonyl amino acid urethane hydrolase I

Class

Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides

Sysname

N-benzyloxycarbonylglycine urethanehydrolase

Reaction(IUBMB)

N-benzyloxycarbonylglycine + H2O = benzyl alcohol + CO2 + glycine [RN:R02551]

Reaction(KEGG)

R02551

Substrate

N-benzyloxycarbonylglycine [CPD:C03710];
H2O [CPD:C00001]

Product

benzyl alcohol [CPD:C00556];
CO2 [CPD:C00011];
glycine [CPD:C00037]

Comment

Also acts, more slowly, on N-benzyloxycarbonylalanine, but not on the corresponding derivatives of other amino acids or on N-benzyloxycarbonylpeptides. Requires Co2+ or Zn2+. cf. EC 3.5.1.64, Nalpha-benzyloxycarbonylleucine hydrolase.

History

EC 3.5.1.58 created 1989

Reference

Authors

Murao S, Matsumura E, Kawano T Isolation and characterization of a novel enzyme N.

Title

alpha-benzyloxycarbonyl amino acid urethane hydrolase, from Streptococcus faecalis R ATCC 8043.

Journal

Agric Biol Chem 49:967-972 (1985)

Other DBs

ExplorEnz - The Enzyme Database:

3.5.1.58