KEGG   ENZYME: 3.5.1.68Help
Entry
EC 3.5.1.68                 Enzyme                                 

Name
N-formylglutamate deformylase;
beta-citryl-L-glutamate hydrolase;
formylglutamate deformylase;
N-formylglutamate hydrolase;
beta-citrylglutamate amidase;
beta-citryl-L-glutamate amidohydrolase;
beta-citryl-L-glutamate amidase;
beta-citryl-L-glutamate-hydrolyzing enzyme
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-formyl-L-glutamate amidohydrolase
Reaction(IUBMB)
N-formyl-L-glutamate + H2O = formate + L-glutamate [RN:R00525]
Reaction(KEGG)
Substrate
N-formyl-L-glutamate [CPD:C01045];
H2O [CPD:C00001]
Product
formate [CPD:C00058];
L-glutamate [CPD:C00025]
Comment
The animal enzyme also acts on beta-citryl-L-glutamate and beta-citryl-L-glutamine.
History
EC 3.5.1.68 created 1989
Pathway
ec00340  Histidine metabolism
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
Orthology
K01458  N-formylglutamate deformylase
Genes
ENR: H650_07655
ENF: AKI40_0710
KPZ: KPNIH27_29445
KPV: KPNIH29_26785
KOX: KOX_11970
KOE: A225_1118
KOY: J415_25725
KOM: HR38_10725 HR38_27755
KMI: VW41_12820
KOK: KONIH1_05770
BUF: D8682_25000(hutG)
METY: MRY16398_22200(hutG)
IZH: FEM41_05050(hutG)
EBC: C2U52_20605(hutG)
PSTS: E05_09480
YPE: YPO1971(hutG)
YPK: y2341
YPH: YPC_2352(hutG)
YPA: YPA_1353
YPN: YPN_1451
YPM: YP_1713(hutG)
YPG: YpAngola_A2513(hutG)
YPZ: YPZ3_1847(hutG)
YPD: YPD4_1735(hutG)
YPX: YPD8_1813(hutG)
YPW: CH59_4159(hutG)
YPJ: CH55_768(hutG)
YPV: BZ15_1570(hutG)
YPL: CH46_3144(hutG)
YPS: YPTB1965(hutG)
YPO: BZ17_504(hutG)
YPI: YpsIP31758_2114(hutG)
YPY: YPK_2223
YPB: YPTS_2020
YPQ: DJ40_348(hutG)
YPU: BZ21_1241(hutG)
YPR: BZ20_150(hutG)
YPC: BZ23_1522(hutG)
YPF: BZ19_1313(hutG)
YEN: YE2462(hutG)
YEY: Y11_12171
YEL: LC20_02353(hutG)
YEW: CH47_1811(hutG)
YET: CH48_3491(hutG)
YEE: YE5303_21231(hutG)
YAL: AT01_642(hutG)
YFR: AW19_988(hutG)
YIN: CH53_3739(hutG)
YKR: CH54_675(hutG)
YRO: CH64_344(hutG)
YRU: BD65_127(hutG)
YMA: DA391_12755(hutG)
YHI: D5F51_09950(hutG)
YCA: F0T03_12330(hutG)
SMAR: SM39_1542(hutG)
SMAC: SMDB11_1352(hutG)
SPE: Spro_2076
SPLY: Q5A_010455
SMAF: D781_1902
SERF: L085_18285
SERA: Ser39006_009665(hutG)
SERQ: CWC46_09660(hutG)
SERM: CLM71_09430(hutG)
SQU: E4343_05825(hutG)
RAA: Q7S_10910
PEC: W5S_4736
SOD: Sant_2172
DFN: CVE23_15495(hutG)
DDQ: DDI_2865
DIC: Dpoa569_001004(hutG)
BNG: EH206_02845(hutG)
EAM: EAMY_1260(hutG)
EAY: EAM_1259(hutG)
ETA: ETA_22190(hutG)
EPY: EpC_23510(hutG)
EPR: EPYR_02541(hutG)
EBI: EbC_14190(hutG)
ERJ: EJP617_23770(hutG)
EPE: CI789_11555(hutG)
ERWI: GN242_14010(hutG)
PAM: PANA_1270
PLF: PANA5342_3015(hutG)
PAJ: PAJ_0591(hutG)
PVA: Pvag_0650(hutG)
PAGG: AL522_10555(hutG)
PSTW: DSJ_09125
PANS: FCN45_06395(hutG)
PEY: EE896_13310(hutG)
PDZ: HHA33_12635(hutG)
XCC: XCC1578(hutG)
XCB: XC_2656
XCP: XCR_1857(hutG)
XCV: XCV1677(hutG)
XAX: XACM_1607(hutG)
XAC: XAC1636(hutG)
XCI: XCAW_02687(hutG)
XFU: XFF4834R_chr28710(hutG)
XOM: XOO2279(XOO2279)
XOO: XOO2399(hutG)
XOP: PXO_00728(hutG)
XOR: XOC_2888(hutG)
XAL: XALC_1718(hutG)
XPH: XppCFBP6546_18480(XppCFBP6546P_18480)
XVA: C7V42_08805(hutG)
XHY: FZ025_01490(hutG)
XCZ: EBN15_06940(hutG)
SML: Smlt3109
SMT: Smal_2551
SMZ: SMD_2692
SACZ: AOT14_20140(hutG)
STEN: CCR98_13250(hutG)
STEM: CLM74_13565(hutG)
STES: MG068_13205(hutG)
PSUW: WQ53_02950
LAB: LA76x_3715(hutG)
LAQ: GLA29479_876(hutG)
LCP: LC55x_3713(hutG)
LGU: LG3211_1495(hutG)
LEZ: GLE_1471(hutG)
LEM: LEN_3491
LYT: DWG18_09215(hutG)
LUE: DCD74_05985(hutG)
LYJ: FKV23_05440(hutG)
LSOL: GOY17_05570(hutG)
LUG: FPZ22_03435(hutG)
THES: FHQ07_04210(hutG)
THEH: G7079_10620(hutG)
XBC: ELE36_11630(hutG)
RGL: CS053_05980(hutG)
DYE: EO087_08415(hutG)
DKO: I596_1813
LPY: FIV34_14515(hutG)
XBA: C7S18_05885(hutG)
PAE: PA5091(hutG)
PAEV: N297_5264(hutG)
PAEI: N296_5264(hutG)
PAU: PA14_67240(hutG)
PAG: PLES_54811(hutG)
PAF: PAM18_5205(hutG)
PNC: NCGM2_0419(hutG)
PAEB: NCGM1900_5848(hutG)
PAEP: PA1S_27575
PAEM: U769_27815
PAEL: T223_28025
PAEU: BN889_05656(hutG)
PAEG: AI22_06430
PAEC: M802_5262(hutG)
PAEO: M801_5129(hutG)
PRE: PCA10_53010(hutG)
PPU: PP_5029(hutG)
PPF: Pput_4903
PPT: PPS_4874
PPB: PPUBIRD1_4817(hutG)
PPI: YSA_04155
PPX: T1E_2484
PPUH: B479_24610
PPUT: L483_30305
PPUN: PP4_50960(hutG)
PPUD: DW66_5266
PMON: X969_24070
PMOT: X970_23705
PSB: Psyr_4836
PSYR: N018_01285
PAMG: BKM19_028050(hutG)
PAVL: BKM03_27765(hutG)
PFL: PFL_0410(hutG_2)
PPRC: PFLCHA0_c04170(hutG2)
PPRO: PPC_0424(hutG_2)
PFS: PFLU_0370
PFE: PSF113_0388(hutG)
PFC: PflA506_0354(hutG)
PFB: VO64_3446
PMAN: OU5_3094
PFW: PF1751_v1c03440(hutG)
PEN: PSEEN5093(hutG)
PPUU: PputUW4_00309(hutG)
PKC: PKB_5389(hutG)
PSEM: TO66_01995
PSOS: POS17_0401(hutG_2)
PANR: A7J50_0357
PSET: THL1_5342
PSIL: PMA3_01305
PKE: DLD99_02140(hutG)
AVN: Avin_26150(hutG)
AVL: AvCA_26150(hutG)
AVD: AvCA6_26150(hutG)
ACX: Achr_21460(hutG)
PAGR: E2H98_04315(hutG)
CPS: CPS_4353
COLA: DBO93_17385(hutG)
CBER: B5D82_07160(hutG)
COV: EKO29_19105(hutG)
THT: E2K93_07700(hutG)
THAP: FNC98_00505(hutG)
AMAE: I876_05095
AMAO: I634_06315
ALR: DS731_19020(hutG)
GNI: GNIT_1603
GPS: C427_1437
KIM: G3T16_18480(hutG)
TMC: LMI_0466
HAM: HALO3089
KKO: Kkor_1530
KGE: TQ33_0919
PSE: NH8B_3768
REH: H16_A1306(hutG3) H16_A3013(hutG1) H16_A3649(hutG4)
CNC: CNE_1c10530(hutG1) CNE_1c29670(hutG3) CNE_1c36000(hutG4)
RME: Rmet_2850(hutG1) Rmet_3507(hutG4)
BMA: BMA0652(hutG) BMAA1476
BMV: BMASAVP1_A2360(hutG)
BMAL: DM55_2017(hutG)
BMAE: DM78_1235(hutG) DM78_4061
BMAQ: DM76_1992(hutG)
BMAF: DM51_3187 DM51_429(hutG)
BMAZ: BM44_1506(hutG) BM44_4943
BMAB: BM45_1069(hutG) BM45_3845
BPR: GBP346_A2838(hutG)
BPSE: BDL_3151(hutG) BDL_6182
BPSM: BBQ_5922 BBQ_973(hutG)
BPSU: BBN_1100(hutG) BBN_3673
BPSD: BBX_1552(hutG) BBX_5351
BPK: BBK_2619(hutG) BBK_5490
BPSH: DR55_2182(hutG) DR55_5069
BPSA: BBU_3223(hutG) BBU_5839
BPSO: X996_1826(hutG) X996_4837
BUT: X994_4336 X994_98(hutG)
BTE: BTH_I1826(hutG)
BTQ: BTQ_2088(hutG)
BTJ: BTJ_224(hutG)
BTZ: BTL_1518(hutG)
BTD: BTI_1296(hutG)
BTV: BTHA_1622(hutG)
BTHE: BTN_3257(hutG)
BTHM: BTRA_1744(hutG)
BTHA: DR62_27
BTHL: BG87_1731(hutG)
BOK: DM82_1953(hutG) DM82_4287
BOC: BG90_2759(hutG) BG90_3730
BVE: AK36_1726(hutG)
BCN: Bcen_5911
BCJ: BCAL2240
BCEN: DM39_2247(hutG) DM39_5276
BCEW: DM40_2811(hutG)
BCEO: I35_2168
BAM: Bamb_2205
BMJ: BMULJ_02152(hutG)
BMU: Bmul_1104
BMK: DM80_2800(hutG)
BMUL: NP80_2286(hutG)
BCED: DM42_2921(hutG)
BDL: AK34_945(hutG)
BCON: NL30_25705
BUB: BW23_2740(hutG)
BLAT: WK25_10530
BTEI: WS51_21200
BSEM: WJ12_10920
BSTG: WT74_11360
BGU: KS03_3284(hutG)
BGO: BM43_296(hutG) BM43_7117(hutG)
BUK: MYA_1953
BUL: BW21_1444(hutG)
BGP: BGL_1c26780(hutG)
BXE: Bxe_A2941
BXB: DR64_623(hutG)
BFN: OI25_1271 OI25_191(hutG)
PARB: CJU94_17380(hutG)
PTER: C2L65_09910(hutG)
PGP: CUJ91_06550(hutG)
PCJ: CUJ87_10125(hutG)
PTS: CUJ90_12475(hutG)
PMEG: FNZ07_20395(hutG)
PPNO: DA70_14025
PPNM: LV28_16655
PPUL: RO07_10795
BPE: BP2725
BPT: Bpet2730 Bpet3694(hutG2)
BAV: BAV0457(hutG)
PUT: PT7_3288
AMIM: MIM_c39160
AFQ: AFA_17390(hutG)
AAQU: D3M96_18625(hutG)
KGY: EHF36_02380(hutG)
RFR: Rfer_4155
RHG: EXZ61_10660(hutG)
POL: Bpro_1166
ACRA: BSY15_1275 BSY15_3175(hutG)
RTA: Rta_18580
HYB: Q5W_16180
HYC: E5678_07410(hutG)
SIMP: C6571_06530(hutG)
JAG: GJA_604(hutG)
JSV: CNX70_26190(hutG)
JAS: FJQ89_15340(hutG)
HEE: hmeg3_23900(hutG)
HHF: E2K99_12025(hutG)
CFU: CFU_2384(hutG)
MASS: CR152_11745(hutG)
MASZ: C9I28_04920(hutG)
MTIM: DIR46_16475(hutG)
MASY: DPH57_16955(hutG)
MALI: EYF70_01530(hutG)
MUM: FCL38_16990(hutG)
MFLA: GO485_12485(hutG)
MPLI: E1742_12920(hutG)
UPV: EJN92_11510(hutG)
DUG: HH213_07320(hutG)
LCH: Lcho_0159
THI: THI_0810
RGE: RGE_38140(hutG)
AON: DEH84_18670(hutG)
MEH: M301_1422
AZO: azo3002(hutG)
AOA: dqs_3138
DALK: DSCA_22800
HOH: Hoch_1854
MLO: mlr8322
MESM: EJ066_20205(hutG)
MESP: C1M53_28235(hutG)
MHUA: MCHK_1629(hutG)
MES: Meso_2984
NIY: FQ775_16755(hutG)
SME: SM_b21164(hutG)
SMX: SM11_pD0764(hutG)
SMEL: SM2011_b21164(hutG)
SMER: DU99_29245
SMD: Smed_4657
SFH: SFHH103_05726(hutG)
SIX: BSY16_1563(hutG)
ATU: Atu3932
AVI: Avi_5957(hutG) Avi_8166
AGC: BSY240_2759(hutG)
ARO: B0909_18405(hutG) B0909_24410(hutG)
AGT: EYD00_18495(hutG)
ALF: CFBP5473_00765(hutG)
REC: RHECIAT_PA0000077(hutG)
REL: REMIM1_PD00072(hutG)
REP: IE4803_PA00080(hutG)
REI: IE4771_PC00071(hutG)
RLG: Rleg_6924
RHN: AMJ98_PD00084(hutG)
RPHA: AMC79_PB00073(hutG)
RHX: AMK02_PE00085(hutG)
RHK: Kim5_PB00076(hutG)
REZ: AMJ99_PC00084(hutG)
RGR: FZ934_21025(hutG)
RAD: CO657_31565(hutG)
SHZ: shn_06940
BME: BMEII0366
BMEL: DK63_2873(hutG)
BMI: BMEA_B0915(hutG)
BMZ: BM28_B0900(hutG)
BMG: BM590_B0898(hutG)
BMEE: DK62_2524(hutG)
BMF: BAB2_0304
BMB: BruAb2_0302(hutG)
BABO: DK55_2296(hutG)
BABR: DO74_2716(hutG)
BABT: DK49_2935(hutG)
BABB: DK48_2396(hutG)
BABU: DK53_2307(hutG)
BABS: DK51_2886(hutG)
BABC: DO78_2754(hutG)
BMS: BRA0931(hutG)
BSI: BS1330_II0923(hutG)
BSF: BSS2_II0883(hutG)
BSUI: BSSP1_II0879(hutG)
BSUP: BSPT1_II0876(hutG)
BSUV: BSPT2_II0877(hutG)
BSUC: BSSP2_II0887(hutG)
BMT: BSUIS_B0924(hutG)
BSZ: DK67_2884(hutG)
BSV: BSVBI22_B0922(hutG)
BOV: BOV_A0873(hutG)
BCS: BCAN_B0951(hutG)
BOL: BCOUA_II0931(hutG)
BCAR: DK60_2622(hutG)
BCAS: DA85_14940
BMR: BMI_II925(hutG)
BPP: BPI_II987(hutG)
BPV: DK65_2721(hutG)
BVL: BF3285c2_0460(hutG)
OAN: Oant_1434
OAH: DR92_1000(hutG)
OCH: CES85_1877(hutG)
BOS: BSY19_1404(hutG)
BOF: FQV39_12815(hutG)
SNO: Snov_3565
LNE: FZC33_28960(hutG)
APRA: G3A50_18505(hutG)
MET: M446_1652
MNO: Mnod_1037
MAQU: Maq22A_c03970(hutG)
MTEA: DK419_07415(hutG)
MICO: GDR74_08790(hutG)
PHL: KKY_3832
MMED: Mame_01254
THD: BHV28_12920(hutG)
HDI: HDIA_0134
NOH: G5V57_07155(hutG)
CCR: CC_0958
CAK: Caul_1296
CMB: CSW64_20195(hutG)
CFH: C1707_12390(hutG)
CAUF: CSW63_18355(hutG)
PZU: PHZ_c0467(hutG)
BVC: CEP68_15380(hutG)
BREV: E7T10_08900(hutG)
BMED: GYM46_15840(hutG)
SIL: SPO2192a(hutG)
RUA: D1823_19360(hutG)
RDE: RD1_2061 RD1_3679(hutG)
RPON: G3256_04685(hutG)
PDE: Pden_0712
PYE: A6J80_14560(hutG)
PZH: CX676_06565(hutG)
PKD: F8A10_09290(hutG)
PPAN: ESD82_18300(hutG)
KVU: EIO_2911
KRO: BVG79_p1000051(hutG)
PGA: PGA1_c36330(hutG)
PGL: PGA2_c34510(hutG)
PGD: Gal_03701
PHP: PhaeoP97_02195(hutG_1) PhaeoP97_03539(hutG_2)
PPIC: PhaeoP14_03441(hutG)
PHQ: D1820_13145(hutG)
OAT: OAN307_c42070(hutG)
OAR: OA238_c03620(hutG)
LEJ: ETW24_21235(hutG)
LAQU: R2C4_00275(hutG)
CEH: CEW89_04955(hutG)
MALG: MALG_04368
RSU: NHU_01257(hutG)
YPAC: CEW88_13595(hutG)
SULZ: C1J03_01100(hutG)
SULI: C1J05_06570(hutG)
ROM: EI983_00665(hutG)
RBG: BG454_17860(hutG)
THAA: CFI11_16940(hutG)
SEDI: EBB79_23275(hutG)
HML: HmaOT1_02725(hutG)
BOO: E2K80_12520(hutG)
PPRU: FDP22_01310(hutG)
PAED: G5B38_05500(hutG) G5B38_20900(hutG)
MALU: KU6B_55920
THAS: C6Y53_02885(hutG)
HNE: HNE_2397(hutG)
GAK: X907_1924
SAL: Sala_1690
SPHP: LH20_14955
SMAZ: LH19_13780
SGI: SGRAN_3305(hutG)
SPHO: C3E99_11290(hutG)
SPHX: E5675_04480(hutG)
SPHU: SPPYR_0407
SWI: Swit_4631
SPHD: HY78_01985
SPHM: G432_01680
SSAN: NX02_15320
SPKC: KC8_03300
SPHC: CVN68_19960(hutG)
SPHA: D3Y57_16085(hutG)
SPHT: K426_21354
SYA: A6768_06430(hutG)
SUFL: FIL70_19870(hutG)
RDI: CMV14_14335(hutG)
SMIC: SmB9_23480
ERR: DVR09_00440(hutG)
ALB: AEB_P2525
GOX: GOX1165
ACR: Acry_1748
AMV: ACMV_17930(hutG)
GXL: H845_1130
KEU: S101446_00264(hutG)
SHUM: STHU_29060
RRU: Rru_A1300
RRF: F11_06725
RCE: RC1_1764 RC1_3237(hutG)
AZL: AZL_006310 AZL_013180(hutG) AZL_c00060(hutG)
TMO: TMO_2345
TXI: TH3_18785
THAC: CSC3H3_23350(hutG)
TII: DY252_19110(hutG)
NAO: Y958_04255 Y958_25565(hutG) Y958_26935(hutG)
FER: FNB15_13080(hutG)
MGM: Mmc1_3085
ECOG: FIV45_00575(hutG)
PHR: C6569_18205(hutG)
PSTG: E8M01_12000(hutG)
BBA: Bd1603
BBAT: Bdt_1597
BBW: BDW_05520
BBAC: EP01_04230
BEX: A11Q_1515
BBEV: BBEV_2605
BSE: Bsel_0709
AAD: TC41_1774
LHV: lhe_1099
CKL: CKL_3857
CKR: CKR_3404
AMT: Amet_3743
MVA: Mvan_2533
SALS: SLNWT_0094
STRD: NI25_04190
DFC: DFI_06290
RUL: UC8_40400
PAA: Paes_0604
CACI: CLOAM0314
MEMA: MMAB1_3050
MBN: Mboo_0639
 » show all
Taxonomy
Reference
1  [PMID:3308850]
  Authors
Hu L, Mulfinger LM, Phillips AT.
  Title
Purification and properties of formylglutamate amidohydrolase from Pseudomonas putida.
  Journal
J Bacteriol 169:4696-702 (1987)
DOI:10.1128/JB.169.10.4696-4702.1987
Reference
2  [PMID:6414521]
  Authors
Miyake M, Innami T, Kakimoto Y.
  Title
A beta-citryl-L-glutamate-hydrolysing enzyme in rat testes.
  Journal
Biochim Biophys Acta 760:206-14 (1983)
DOI:10.1016/0304-4165(83)90165-4
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.68
IUBMB Enzyme Nomenclature: 3.5.1.68
ExPASy - ENZYME nomenclature database: 3.5.1.68
BRENDA, the Enzyme Database: 3.5.1.68
CAS: 97286-12-9

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