KEGG   ENZYME: 3.5.1.76
Entry
EC 3.5.1.76                 Enzyme                                 
Name
arylalkyl acylamidase;
aralkyl acylamidase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
N-acetylarylalkylamine amidohydrolase
Reaction(IUBMB)
N-acetylarylalkylamine + H2O = arylalkylamine + acetate [RN:R04727]
Reaction(KEGG)
R04727
Substrate
N-acetylarylalkylamine [CPD:C02998];
H2O [CPD:C00001]
Product
arylalkylamine [CPD:C01890];
acetate [CPD:C00033]
Comment
Identified in Pseudomonas putida. Strict specificity for N-acetyl arylalkylamines, including N-acetyl-2-phenylethylamine, N-acetyl-3-phenylpropylamine, N-acetyldopamine, N-acetyl-serotonin and melatonin. It also accepts arylalkyl acetates but not acetanilide derivatives, which are common substrates of EC 3.5.1.13, aryl acylamidase.
History
EC 3.5.1.76 created 1999
Reference
1  [PMID:1396711]
  Authors
Shimizu S, Ogawa J, Chung MC, Yamada H.
  Title
Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2.
  Journal
Eur J Biochem 209:375-82 (1992)
DOI:10.1111/j.1432-1033.1992.tb17299.x
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.76
IUBMB Enzyme Nomenclature: 3.5.1.76
ExPASy - ENZYME nomenclature database: 3.5.1.76
BRENDA, the Enzyme Database: 3.5.1.76

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (9)   

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