Entry
Name
dCMP deaminase;
deoxycytidylate deaminase;
deoxy-CMP-deaminase;
deoxycytidylate aminohydrolase;
deoxycytidine monophosphate deaminase;
deoxycytidine-5'-phosphate deaminase;
deoxycytidine-5'-monophosphate aminohydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
BRITE hierarchy
Sysname
dCMP aminohydrolase
Reaction(IUBMB)
dCMP + H2O = dUMP + NH3 [RN:
R01663 ]
Reaction(KEGG)
Substrate
Product
Comment
Also acts on some 5-substituted dCMPs.
History
EC 3.5.4.12 created 1965
Pathway
Orthology
K26030 Straboviridae deoxycytidylate deaminase
Genes
DORD : 105993426(Dctd) 105999659
BMUS : 118888008(DCTD) 118890506
PSIU : 116746309 116746748(DCTD)
NASI : 112401352 112410341
EPZ : 103556164(DCTD) 103567706
MMYO : 118651288(DCTD) 118669355
MJV : 108390993(DCTD) 118969621 118972108
BBUF : 120991009 120991759
GSH : 117359766(DCTD) 117359779
SRX : 107737125(dctd) 107748833
SANH : 107671033 107684975
CAUA : 113095023(dctd) 113109152
IPU : 108263713 108263714(dctd)
IFU : 128606126 128606127 128606128(dctd)
PHYP : 113538243 113541301 113544637
SMEO : 124377131(dctd) 124401110
TFD : 113649304 113649311 113649320 113661193(dctd) 125140539 125140540
TVC : 132846753 132847705(dctd) 132847759 132847760
TBEN : 117474867(dctd) 117479407 117479408 117479412 117479413 117479414 117496588
PGEO : 117449752 117453521(dctd) 117454087
GACU : 117540741 117540742 117551597(dctd)
ELY : 117254578(dctd) 117256048 117256051
EFO : 125885177(dctd) 125885765 125886282
CUD : 121507950(dctd) 121515335
ALAT : 119020632 119020660
PFOR : 103146624 103146626
PLAI : 106940578 106954504 106956030
SSEN : 122770894 122770901
BPEC : 110155999(dctd) 110167586
SJO : 128373081(dctd) 128375430
SASA : 106602441(DCTD) 106610063(DCTD)
STRU : 115191834 115202195
OGO : 124013217(dctd) 124017143
OKE : 118363021 118395556(dctd)
SALP : 111958466 111971607
AANG : 118226815 118226816
ARUT : 117408870 117974139(dctd)
SPU : 115922182 575919 580835
LPIC : 129260651 129261468 129283757
ARUN : 117294038 117305680
DSI : Dsimw501_GD14864(Dsim_GD14864)
LCQ : 111681193 111681223 111681224
LSQ : 119609702 119609707 119609709 119609710
CLON : 129605930 129607734 129612581
OBB : 114873276 114875813 114876062
SOC : 105196476 105205936 105206016
OBO : 105279294 105279296 105279319 105286596 113562024 113562025 113562026
SOY : 115886074 115887362 115887399
CSET : 123307263 123309425
NVL : 108568576 108568580 108568581
APLN : 108740210 108742834 108742835
OTU : 111413468 111418313 111420165 111420475 111423636
CEL : CELE_ZK643.2(ZK643.2)
TSP : Tsp_05426 Tsp_07422a Tsp_13353 Tsp_13729
LGI : LOTGIDRAFT_170797 LOTGIDRAFT_209389
PVUL : 126830941 130014100
PCAN : 112559202 112559203
HRF : 124126367 124126368 124151366 124151369 124151371 124151380
HRJ : 124284225 124284233 124284234 124284235 124284236 124284240
CANU : 128155539 128169017
MYI : 110454832 110454833 110454835 110454847 110454849 110454861
PMAX : 117319865 117329067 117329068
MCAF : 127703954 127716547 127716548 127716550 127726192
MMER : 123557263 123557265 123557267 123557269 123557392 123559036 128554971 128557061 128557062
RPHI : 132714824 132725517 132746095 132748984 132751560
MAEA : 128203119 128225545 128226226 128226701 128226760 128228886
OSN : 115211933 115213032 115213328 115214920 115216699 115216708 115228725
LAK : 106155134 106155137 106169130
LLON : 135494499 135495060 135500357 135501308 135501430 135501809
PDAM : 113681108 113681767
AQU : 100633670 100635558 100639683 109581041 109587438 109588298
CSAT : 104711350 104780669 104791072
HSYR : 120193517 120210079
PALZ : 118044668 118057652
ECAD : 122608636 122608786
PSOM : 113274379 113277296
TAES : 123062161 123070885 123079275
MFLO : 136453048 136453306 136459080
NCOL : 116245584 116248718
SMO : SELMODRAFT_136875 SELMODRAFT_420076 SELMODRAFT_6274
CGR : 2888266(GVI51_G05687)
NCS : NCAS_0D00460(NCAS0D00460)
NDI : NDAI_0G02790(NDAI0G02790)
TPF : TPHA_0F02270(TPHA0F02270)
TBL : TBLA_0B00860(TBLA0B00860)
TDL : TDEL_0F00720(TDEL0F00720)
KAF : KAFR_0F00440(KAFR0F00440)
KNG : KNAG_0H03810(KNAG0H03810)
LBG : 92206488(LODBEIA_P12920)
CAL : CAALFM_C114310WA(CaO19.7243)
YLI : 2909630(YALI2_B00362g)
NTE : NEUTE1DRAFT127453(NEUTE1DRAFT_127453)
SMP : 10803397(SMAC4_06538)
TATV : 25775721(TrAtP1_006862)
TASP : 36608563(TrAFT101_006065)
PLJ : 28886718(PLICBS_002047)
BFU : BCIN_09g04720(Bcdcd1)
PTRR : 6339670(PtrM4_028320)
KMG : 30164697(I203_107990)
KNE : 92177798(IAR55_000538)
CCAC : CcaHIS019_0508000(DCD1)
PPL : POSPLDRAFT_89630 POSPLDRAFT_90272
ABP : AGABI1DRAFT124430(AGABI1DRAFT_124430)
ABV : AGABI2DRAFT113851(AGABI2DRAFT_113851)
SCM : SCHCO_02487636(SCHCODRAFT_02487636)
MLR : MELLADRAFT_35707 MELLADRAFT_54347
MBR : MONBRDRAFT_3136 MONBRDRAFT_33129
SRE : PTSG_06653 PTSG_09425
PTM : GSPATT00000804001 GSPATT00031368001
PIF : PITG_06977 PITG_20614
LRI : NCTC12151_00457(tadA_1)
SINL : DSM14862_00291(tadA_1)
SBF : JCM31447_29350(dctD)
BSH : BSU6051_25580(comEB)
BAML : BAM5036_2308(comEB)
BAZ : BAMTA208_13125(comEB)
BCR : BCAH187_A4459(comEB)
BCB : BCB4264_A4446(comEB)
BCG : BCG9842_B0791(comEB)
BMET : BMMGA3_12090(comEB)
BFD : NCTC4823_01772(comEB)
BKW : BkAM31D_05200(comEB)
SCIA : HUG15_05280 HUG15_05615
BLEN : NCTC4824_01633(comEB)
ALKL : MM271_08500 MM271_12770
SAX : USA300HOU_1590(comEB)
SUK : SAA6008_01559(comEB)
SAUT : SAI1T1_2011550(comEB)
SAUJ : SAI2T2_1011570(comEB)
SAUK : SAI3T3_1011550(comEB)
SAUQ : SAI4T8_1011560(comEB)
SAUV : SAI7S6_1011570(comEB)
SAUW : SAI5S5_1011520(comEB)
SAUX : SAI6T6_1011530(comEB)
SAUY : SAI8T7_1011560(comEB)
SDP : NCTC12225_01418(comEB)
SCAP : AYP1020_0886(tadA_1)
SPIC : SAMEA4384060_1358(ribD_2)
SSH : NCTC13712_01585(tadA_2)
SSIM : SAMEA4384339_1479(tadA_2)
LMOC : LMOSLCC5850_1545(comEB)
LMOL : LMOL312_1481(comEB)
LMW : LMOSLCC2755_1488(comEB)
LMX : LMOSLCC2372_1545(comEB)
LMZ : LMOSLCC2482_1538(comEB)
LMON : LMOSLCC2376_1438(comEB)
LMOS : LMOSLCC7179_1456(comEB)
LMOO : LMOSLCC2378_1499(comEB)
LMOY : LMOSLCC2479_1544(comEB)
LMOT : LMOSLCC2540_1562(comEB)
LMOA : LMOATCC19117_1492(comEB)
BLR : BRLA_c013630(ribD_1)
BAYD : BSPP4475_13220(dedD)
PPQ : PPSQR21_034460(comEB)
PKP : SK3146_06241(tadA_2)
SURL : BI350_07580 BI350_10480
SPZ : M5005_Spy1548(comEB)
SPYM : M1GAS476_1625(comE)
SPH : MGAS10270_Spy1615(comEB)
SPI : MGAS10750_Spy1607(comEB)
SPJ : MGAS2096_Spy1573(comEB)
SPK : MGAS9429_Spy1552(comEB)
STG : MGAS15252_1391(comEB)
STX : MGAS1882_1452(comEB)
STZ : SPYALAB49_001538(comEB)
SPNG : HMPREF1038_00757(comEB)
SMC : SmuNN2025_0289(comEB)
SSAH : HSISS4_01647(comEB)
SVB : NCTC12167_01676(comEB)
SMEN : SAMEA4412692_1380(comEB)
SFER : NCTC12278_01630(tadA_1)
SCAI : NCTC12191_00964(comEB)
SPSU : NCTC13786_01497(comEB)
SPOC : NCTC10925_01660(comEB)
SURN : NCTC13766_01779(comEB)
SMIE : NCTC11169_00934(ribD)
SPAM : SP4011_15690(comEB)
LPW : LpgJCM5343_02030(comEB)
LBN : LBUCD034_0794(comEB)
LHIL : G8J22_01010(tadA_1)
EFU : HMPREF0351_11245(comEB)
VLC : G314FT_12000(tadA_2)
JDA : BW727_100521(tadA_1)
CLB : Clo1100_0283 Clo1100_1538
CSEP : CP523_01840 CP523_10140
CMAH : C1I91_07110 C1I91_23695
CINT : HZF06_01125 HZF06_19535
CLOD : C820_001182(tadA_2)
BPRO : PMF13cell1_02478(tadA_2)
CSCI : HDCHBGLK_01034(tadA_2)
ANR : Ana3638_01805 Ana3638_21015
WHJ : H9Q79_11335 H9Q79_17975
CDF : CD630_18990 CD630_34770
PDC : CDIF630_02104(comEB1) CDIF630_03788(comEB2)
CDC : CD196_1774 CD196_3267
CDL : CDR20291_1819 CDR20291_3313
PDF : CD630DERM_18990 CD630DERM_34770
PHX : KGNDJEFE_02292(tadA_2)
VRM : 44547418_00980(ribD_2)
VDN : NCTC11831_00982(ribD_1)
PFAC : PFJ30894_00813(tadA_1)
ERB : A4V01_07035 A4V01_11030
CIU : G4D55_05585 G4D55_09425
MCAP : MCCPF38_00484(ribD)
MCAR : MCCPILRI181_00481(ribD)
MPUT : MPUT9231_3590(dctD)
AHK : NCTC10172_00523(ribD)
AAXA : NCTC10138_01184(ribD)
MTAB : MTABA_v1c04360(comEB)
MCOL : MCOLE_v1c03990(comEB)
EML : EMELA_v1c05350(comEB)
EFR : EFREU_v1c04790(comEB)
ELJ : ELUMI_v1c04430(comEB)
ESX : ESOMN_v1c02940(comEB)
SCR : SCHRY_v1c06440(comEB)
SSYR : SSYRP_v1c06660(comEB)
SDI : SDIMI_v3c06130(comEB)
STAI : STAIW_v1c08530(comEB)
SAPI : SAPIS_v1c07280(comEB)
SCQ : SCULI_v1c07630(comEB)
SSAB : SSABA_v1c05910(comEB)
SATR : SATRI_v1c07660(comEB)
SERI : SERIO_v1c07470(comEB)
STUR : STURON_00252(comEB)
SLL : SLITO_v1c02660(comEB)
SCJ : SCANT_v1c07580(comEB)
SHJ : SHELI_v1c07030(comEB)
SCK : SCITRI_001137(comEB)
SFZ : SFLOR_v1c08100(comEB)
SCOU : SCORR_v1c02520(comEB)
SCLA : SCLARK_00794(comEB)
SPRN : S100390_v1c07050(comEB)
SPIT : STU14_v1c07050(comEB)
STAB : STABA_v1c07780(comEB)
SMOO : SMONO_v1c05820(comEB)
SALX : SALLE_v1c06110(comEB)
SGQ : SGLAD_v1c07280(comEB)
SCHI : SCHIN_v1c08900(comEB)
MPU : MYPU_2780(MYPU_2780)
MFM : MfeM64YM_0007(comEB)
MARG : MARG145_0159(comEB)
MCAN : MCAN360_0377(comEB)
MGN : HFMG06NCA_0349(folA_cd)
MGS : HFMG95NCA_0350(folA_cd)
MGT : HFMG01NYA_0349(folA_cd)
MGV : HFMG94VAA_0350(folA_cd)
MGW : HFMG01WIA_0351(folA_cd)
MGAC : HFMG06CAA_0347(folA_cd)
MGAN : HFMG08NCA_0348(folA_cd)
MGNC : HFMG96NCA_0350(folA_cd)
PCAT : Pcatena_02590(comEB)
EYY : EGYY_21060(ComEB_(BS))
PAUS : NCTC13651_02011(ribD_2)
ACIJ : JS278_00869(tadA_2)
TFL : RPIT_13650 RPIT_13890
PRUN : PCC7821_00749(36.1)
OBG : Verru16b_02577(ribD_2)
HABY : HLVA_05760 HLVA_09760
BTHO : Btheta7330_03844(tadA_2)
BOA : Bovatus_04527(tadA_2)
BCEL : BcellWH2_04204(tadA_2)
PCRE : NCTC12858_00198(ribD_1)
PCAG : NCTC12856_00110(tadA_1)
PMUC : ING2E5A_0547(comEB)
POC : NCTC13071_02026(tadA_1)
BLQ : L21SP5_02433(tadA_2)
MGOT : MgSA37_01342(ribD_1)
CHER : DK880_00133(tadA_2)
PHG : KCTC32516_00606(ribD_2)
KOS : KORDIASMS9_01361(ribD)
KAN : IMCC3317_26910(ribD_2)
OHM : MSHRCOH1_01715(ribD)
CGLE : NCTC11432_03005(ribD_1)
CTAI : NCTC12078_01914(ribD_2)
CTAK : 4412677_01394(ribD_1)
CSAL : NBC122_00714(tadA_1)
PTAN : CRYO30217_02881(tadA_1)
MSCH : N508_000107(tadA_1)
SRB : P148_SR1C001G0148 P148_SR1C001G0830
MSZ : MSSIH_0104 MSSIH_0105
MSW : MSSIT_0105 MSSIT_0106
MJK : N2V74_00695 N2V74_05165
TVO : TVG1352610(TVG1352610)
» show all
Taxonomy
Reference
Authors
SCARANO E.
Title
The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate.
Journal
J Biol Chem 235:706-13 (1960)
Reference
Authors
SCARANO E, BONADUCE L, DE PETROCELLISB.
Title
The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine.
Journal
J Biol Chem 235:3556-61 (1960)
Reference
Authors
Sergott RC, Debeer LJ, Bessman MJ.
Title
On the regulation of a bacterial deoxycytidylate deaminase.
Journal
J Biol Chem 246:7755-8 (1971)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.4.12
ExPASy - ENZYME nomenclature database: 3.5.4.12