Entry |
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Name |
cAMP deaminase;
cyclic adenylate deaminase;
CadD
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Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
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Sysname |
3',5'-cyclic AMP aminohydrolase
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Reaction(IUBMB) |
3',5'-cyclic AMP + H2O = 3',5'-cyclic IMP + NH3 [RN: R11619]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Requires Zn2+. The enzyme, isolated from the bacterium Leptospira interrogans, is specific for cAMP.
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History |
EC 3.5.4.46 created 2017
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Orthology |
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Genes |
» show all
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Reference |
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Authors |
Goble AM, Feng Y, Raushel FM, Cronan JE |
Title |
Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. |
Journal |
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Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: | 3.5.4.46 |
ExPASy - ENZYME nomenclature database: | 3.5.4.46 |
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