KEGG   ENZYME: 3.5.5.4
Entry
EC 3.5.5.4                  Enzyme                                 

Name
cyanoalanine nitrilase;
beta-cyanoalanine nitrilase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
Sysname
3-cyano-L-alanine aminohydrolase
Reaction(IUBMB)
3-cyano-L-alanine + 2 H2O = L-aspartate + NH3 (overall reaction) [RN:R00486];
(1a) 3-cyano-L-alanine + H2O = L-asparagine [RN:R01267];
(1b) L-asparagine + H2O = L-aspartate + NH3 [RN:R00485]
Reaction(KEGG)
Substrate
3-cyano-L-alanine [CPD:C02512];
H2O [CPD:C00001];
L-asparagine [CPD:C00152]
Product
L-aspartate [CPD:C00049];
NH3 [CPD:C00014];
L-asparagine [CPD:C00152]
Comment
L-Asparagine is formed as an intermediate. cf. EC 4.2.1.65, 3-cyanoalanine hydratase and EC 3.5.1.1, asparaginase.
History
EC 3.5.5.4 created 1986
Pathway
ec00460  Cyanoamino acid metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K13035  beta-cyano-L-alanine hydratase/nitrilase
Genes
AJM: 119059097
ATH: AT5G22300(NIT4)
ALY: 9310128
CRB: 17881917
CSAT: 104706517 104736238 104770558
EUS: EUTSA_v10013949mg
BRP: 103851433(NIT-T4)
BNA: 106384710 106427339
BOE: 106327565
RSZ: 108843167
THJ: 104810929
PVY: 116105637
VRA: 106775914
VAR: 108339531
VUN: 114168387
CCAJ: 109799314
APRC: 113858884
CAM: 101500877
LJA: Lj3g3v2981810.1(Lj3g3v2981810.1) Lj3g3v2981810.2(Lj3g3v2981810.2) Lj3g3v2981810.3(Lj3g3v2981810.3) Lj3g3v2981810.4(Lj3g3v2981810.4)
ADU: 107478319
AIP: 107630108
LANG: 109351736(NIT4) 109353638(NIT4B)
FVE: 101314432
RCN: 112165679
MDM: 103424813
MNT: 21399366
CSV: 101209360
CMO: 103501743
BHJ: 120083021
MCHA: 111012712
CMAX: 111471660
CMOS: 111434356
CPEP: 111784116
JCU: 105635907
SLY: 101266793
SPEN: 107004945
SOT: 102595618
CANN: 107847983
NTA: 107804379(NIT4A) 107812524 107832013(NIT4B)
NSY: 104235794
NAU: 109229286
INI: 109160194
ITR: 116004786
SIND: 105170044
OEU: 111383075
EGT: 105970138
LSV: 111896404
CCAV: 112529711
DCR: 108215255
CSIN: 114287616
BVG: 104899831
SOE: 110798812
NCOL: 116267212
DOSA: Os02t0635000-01(Os02g0635000) Os02t0635200-01(Os02g0635200)
ZMA: 542093(NIT2) 542573(NIT1)
PDA: 103705226
EGU: 105042779
MUS: 103994490
DCT: 110107670
PEQ: 110023533
AOF: 109825016
SMO: SELMODRAFT_133005(NIT4-2) SELMODRAFT_171766(NIT4-1)
PPP: 112274445
 » show all
Reference
1
  Authors
Yanase, H., Sakai, T. and Tonomuro, K.
  Title
Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13.
  Journal
Agric Biol Chem 47:473-482 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.5.4
IUBMB Enzyme Nomenclature: 3.5.5.4
ExPASy - ENZYME nomenclature database: 3.5.5.4
BRENDA, the Enzyme Database: 3.5.5.4
CAS: 85638-44-4

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