KEGG   ENZYME: 3.5.5.8
Entry
EC 3.5.5.8                  Enzyme                                 

Name
thiocyanate hydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
Sysname
thiocyanate aminohydrolase
Reaction(IUBMB)
thiocyanate + 2 H2O = carbonyl sulfide + NH3 + HO- [RN:R05780]
Reaction(KEGG)
R05780
Substrate
thiocyanate [CPD:C01755];
H2O [CPD:C00001]
Product
carbonyl sulfide [CPD:C07331];
NH3 [CPD:C00014];
HO- [CPD:C01328]
Comment
The enzyme from Thiobacillus thioparus catalyses the first step in the degradation of thiocyanate.
History
EC 3.5.5.8 created 2000
Orthology
K20760  thiocyanate hydrolase subunit alpha
K20761  thiocyanate hydrolase subunit beta
K20762  thiocyanate hydrolase subunit gamma
Genes
LPO: LPO_1236(scnC) LPO_1237 LPO_1238
LPP: lpp1219 lpp1220 lpp1221
LLO: LLO_1905
LSH: CAB17_12325(scnC) CAB17_12330 CAB17_12335
LWA: SAMEA4504053_2104(scnB) SAMEA4504053_2105(scnA) SAMEA4504053_2106(scnC)
SVA: SVA_2685 SVA_2686 SVA_2687 SVA_2692
BGO: BM43_3446(nthA)
BUM: AXG89_23970 AXG89_28720
SPLB: SFPGR_11590 SFPGR_11600 SFPGR_11610
RLG: Rleg_1540
MOR: MOC_3646(nthA)
PAMO: BAR1_06170
HTQ: FRZ44_32640(nthA) FRZ44_50720(nthA)
MPHL: MPHLCCUG_02409(scnB) MPHLCCUG_02410(scnC)
MHAS: MHAS_01849(scnB) MHAS_01850(scnC)
MAUU: NCTC10437_01220(scnC) NCTC10437_01221(scnB)
ROP: ROP_43440(scnC) ROP_43450(scnA) ROP_43460(scnB)
GRU: GCWB2_23795(scnB) GCWB2_23800(scnC)
NCX: Nocox_22935(scnC) Nocox_22940(scnA) Nocox_22945(scnB2)
 » show all
Reference
1  [PMID:9573140]
  Authors
Katayama Y, Matsushita Y, Kaneko M, Kondo M, Mizuno T, Nyunoya H
  Title
Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their evolutionary relationships to nitrile hydratase.
  Journal
J Bacteriol 180:2583-9 (1998)
DOI:10.1128/JB.180.10.2583-2589.1998
  Sequence
Reference
2  [PMID:1577754]
  Authors
Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H
  Title
A thiocyanate hydrolase of Thiobacillus thioparus. A novel enzyme catalyzing the formation of carbonyl sulfide from thiocyanate.
  Journal
J Biol Chem 267:9170-5 (1992)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.5.8
IUBMB Enzyme Nomenclature: 3.5.5.8
ExPASy - ENZYME nomenclature database: 3.5.5.8
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.5.8
BRENDA, the Enzyme Database: 3.5.5.8
CAS: 142539-65-9

DBGET integrated database retrieval system