KEGG   ENZYME: 3.5.5.8
Entry
EC 3.5.5.8                  Enzyme                                 
Name
thiocyanate hydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
Sysname
thiocyanate aminohydrolase
Reaction(IUBMB)
thiocyanate + 2 H2O = carbonyl sulfide + NH3 + HO- [RN:R05780]
Reaction(KEGG)
R05780
Substrate
thiocyanate [CPD:C01755];
H2O [CPD:C00001]
Product
carbonyl sulfide [CPD:C07331];
NH3 [CPD:C00014];
HO- [CPD:C01328]
Comment
The enzyme from Thiobacillus thioparus catalyses the first step in the degradation of thiocyanate.
History
EC 3.5.5.8 created 2000
Orthology
K20760  thiocyanate hydrolase subunit alpha
K20761  thiocyanate hydrolase subunit beta
K20762  thiocyanate hydrolase subunit gamma
Genes
LPOLPO_1236(scnC) LPO_1237 LPO_1238
LPPlpp1219 lpp1220 lpp1221
LLOLLO_1905
LSHCAB17_12325(scnC) CAB17_12330 CAB17_12335
LWASAMEA4504053_2104(scnB) SAMEA4504053_2105(scnA) SAMEA4504053_2106(scnC)
NAXHC341_03860
SVASVA_2685 SVA_2686 SVA_2687 SVA_2692
BGOBM43_3446(nthA)
BUMAXG89_23970 AXG89_28720
SPLBSFPGR_11590 SFPGR_11600 SFPGR_11610
ARUIG6M88_23135
RLGRleg_1540
MPOMpop_4230 Mpop_4231
MORMOC_3646(nthA)
MPHYMCBMB27_05598
RHZRHPLAN_42300
ACUTMRB58_10600(nthA) MRB58_11075(nthA)
PAEDG5B38_07255
PAMOBAR1_06170
HDHG5B40_13625
POQKZX46_00445 KZX46_00450(nthA)
RMTIAI58_22800(scnC) IAI58_22805
SRFLHU95_02830
AZMDM194_21620(scnC) DM194_21625
HTQFRZ44_32640(nthA) FRZ44_50720(nthA)
ELIOKO353_00995
APBSAR116_1730
MITOCO_27870 OCO_27880
MIAOCU_27740 OCU_27750
MIDMIP_03821 MIP_03822
MYOOEM_26340 OEM_26350
MCHIAN480_14595 AN480_14600
MIROCQ_26440 OCQ_26450
MMALCKJ54_12660 CKJ54_12665(scnC)
MMANMMAN_11070 MMAN_11080
MSAMycsm_03329 Mycsm_03330
MMCMmcs_5257 Mmcs_5258
MKMMkms_5346 Mkms_5347
MJLMjls_5636 Mjls_5637
MMMW7S_13500 W7S_13505
MKNMKAN_21490 MKAN_21495
MYVG155_15725 G155_15730
MYEAB431_16060 AB431_16065
MGOAFA91_03540 AFA91_03545
MHADB586_12050 B586_12055
MDXBTO20_03040 BTO20_03045
MFJMFLOJ_07080 MFLOJ_07090
MSTOMSTO_08410 MSTO_08430
MSIMMSIM_52430 MSIM_52440
MGROFZ046_04270(scnC) FZ046_04275
MNVMNVI_44260 MNVI_44270
MPAGC0J29_16280(scnC) C0J29_16285
MHEKJMUB5695_03742(scnC) JMUB5695_03743
MGAUMGALJ_16640 MGALJ_16650
MLJMLAC_17150
MSHJMSHI_23270 MSHI_23280
MDFK0O62_26075(scnC) K0O62_26080
MHOLK3U96_12525(scnC) K3U96_12530
MPAEK0O64_15105 K0O64_15110(scnC)
MOTLTS72_18695(scnC) LTS72_18700
MRFMJO55_06145(scnC) MJO55_06150
MCROMI149_16100 MI149_16105(scnC)
MSMMSMEG_6266 MSMEG_6267
MSGMSMEI_6104 MSMEI_6105
MSBLJ00_30985 LJ00_30990
MSNLI99_30990 LI99_30995
MSHLI98_30995 LI98_31000
MVAMvan_1504 Mvan_1505
MGIMflv_4915 Mflv_4916
MSPMspyr1_43320 Mspyr1_43330
MCBMycch_1104 Mycch_1105
MFTXA26_32230 XA26_32240
MPHLMPHLCCUG_02409(scnB) MPHLCCUG_02410(scnC)
MVQMYVA_1255 MYVA_1256
MLLB1R94_12945
MRHMycrhN_4874 MycrhN_4875
MHASMHAS_01849(scnB) MHAS_01850(scnC)
MDUMDUV_47310 MDUV_47320
MCHTMCHIJ_39080 MCHIJ_39090
MDRMDOR_37020 MDOR_37030
MAUUNCTC10437_01220(scnC) NCTC10437_01221(scnB)
MMORMMOR_33550 MMOR_33560
MAICMAIC_27730 MAIC_27740
MALVMALV_45510 MALV_45520
MTYMTOK_13040 MTOK_13050
MPSCMPSYJ_52350 MPSYJ_52360
MARZMARA_10510 MARA_10520
MGADMGAD_08190 MGAD_08200
MANYMANY_17080 MANY_17090
MAUBMAUB_50880 MAUB_50890
MPHUMPHO_18370 MPHO_18380
MMUCC1S78_009215(scnC) C1S78_009220
MMATMMAGJ_31010 MMAGJ_31020
MBOKMBOE_50570 MBOE_50580
MFGK6L26_20390(scnC) K6L26_20395
MSEIMSEDJ_41300 MSEDJ_41310
MFLVNCTC10271_02504(scnC) NCTC10271_02505(scnB)
MCEEMCEL_07720 MCEL_07730
MIZBAB75_13855 BAB75_13860
MSTEMSTE_04933 MSTE_04934
MHIBMHIB_25770 MHIB_25780
ASDAS9A_3706 AS9A_3707
NFANFA_20750 NFA_20760 NFA_20770
NFRERS450000_02034(scnB_1) ERS450000_02035(scnA) ERS450000_02036(scnC)
NSLBOX37_19925 BOX37_19930
NADNCTC11293_06073(scnB) NCTC11293_06074(scnC)
NTCKHQ06_36155 KHQ06_36160(scnC)
NGPLTT66_20535(scnC)
RHARHA1_ro04428 RHA1_ro04429 RHA1_ro04430
ROPROP_43440(scnC) ROP_43450(scnA) ROP_43460(scnB)
ROAPd630_LPD00881 Pd630_LPD00882 Pd630_LPD00883
REQREQ_06080 REQ_06090 REQ_06100
RCRNCTC10994_02400(scnB_1) NCTC10994_02401(scnA) NCTC10994_02402(scnC)
RKOJWS14_23935(scnC) JWS14_23940 JWS14_23945
ROZCBI38_03700 CBI38_03705 CBI38_03710
GORKTR9_4744 KTR9_4745
GTABCM27_25200 BCM27_25205
GRUGCWB2_23795(scnB) GCWB2_23800(scnC)
GAVC5O27_04695(scnC) C5O27_04700
GODGKZ92_22695 GKZ92_22700(scnC)
GHNMVF96_23755 MVF96_23760(scnC)
GAMIIHQ52_04255(scnC) IHQ52_04260
SCYAEJ357_17540
SAQUEJC51_19945
NCXNocox_22935(scnC) Nocox_22940(scnA) Nocox_22945(scnB2)
PBROHOP40_04470
PFLAPflav_087890
RUBGBA63_05240
RMARGBA65_04825
PSEUPse7367_1909
 » show all
Reference
1  [PMID:9573140]
  Authors
Katayama Y, Matsushita Y, Kaneko M, Kondo M, Mizuno T, Nyunoya H
  Title
Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their evolutionary relationships to nitrile hydratase.
  Journal
J Bacteriol 180:2583-9 (1998)
DOI:10.1128/JB.180.10.2583-2589.1998
  Sequence
Reference
2  [PMID:1577754]
  Authors
Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H
  Title
A thiocyanate hydrolase of Thiobacillus thioparus. A novel enzyme catalyzing the formation of carbonyl sulfide from thiocyanate.
  Journal
J Biol Chem 267:9170-5 (1992)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.5.8
IUBMB Enzyme Nomenclature: 3.5.5.8
ExPASy - ENZYME nomenclature database: 3.5.5.8
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.5.8
BRENDA, the Enzyme Database: 3.5.5.8
CAS: 142539-65-9

DBGET integrated database retrieval system