KEGG   ENZYME: 3.5.99.2
Entry
EC 3.5.99.2                 Enzyme                                 

Name
aminopyrimidine aminohydrolase;
thiaminase (ambiguous);
thiaminase II;
tenA (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In other compounds
Sysname
4-amino-5-aminomethyl-2-methylpyrimidine aminohydrolase
Reaction(IUBMB)
(1) 4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH3 [RN:R09993];
(2) thiamine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole [RN:R02133]
Reaction(KEGG)
R02133 R09993
Substrate
4-amino-5-aminomethyl-2-methylpyrimidine [CPD:C20267];
H2O [CPD:C00001];
thiamine [CPD:C00378]
Product
4-amino-5-hydroxymethyl-2-methylpyrimidine [CPD:C01279];
NH3 [CPD:C00014];
5-(2-hydroxyethyl)-4-methylthiazole [CPD:C04294]
Comment
Previously known as thiaminase II, this enzyme is involved in the regeneration of the thiamine pyrimidine from degraded products, rather than in thiamine degradation, and participates in thiamine salvage pathways.
History
EC 3.5.99.2 created 1961, modified 2011
Pathway
ec00730  Thiamine metabolism
ec01100  Metabolic pathways
Orthology
K00877  hydroxymethylpyrimidine/phosphomethylpyrimidine kinase / thiaminase
K03707  thiaminase (transcriptional activator TenA)
Genes
API: 103310909
QSU: 112029066
OLU: OSTLU_88734
OTA: OT_ostta12g00940
MPP: MICPUCDRAFT_52894
SCE: YOL055C(THI20) YPL258C(THI21)
KLA: KLLA0_B13926g
KMX: KLMA_30047(THI20)
LTH: KLTH0F06732g
VPO: Kpol_1045p51
NCS: NCAS_0C03670(NCAS0C03670)
NDI: NDAI_0G03010(NDAI0G03010)
TPF: TPHA_0P00590(TPHA0P00590)
TBL: TBLA_0B04160(TBLA0B04160) TBLA_0B04170(TBLA0B04170) TBLA_0G00850(TBLA0G00850)
TDL: TDEL_0D04490(TDEL0D04490)
KAF: KAFR_0C00950(KAFR0C00950)
PIC: PICST_70077(THI20)
CAL: CAALFM_C203370WA(THI20)
SLB: AWJ20_1019(THI22)
NCR: NCU07849(thi-4)
NTE: NEUTE1DRAFT80933(NEUTE1DRAFT_80933)
MGR: MGG_16900
SSCK: SPSK_10761
MAJ: MAA_02490
CMT: CCM_09434
MBE: MBM_07084
ANG: ANI_1_2342024(An02g02520)
ABE: ARB_05224
TVE: TRV_02263
PTE: PTT_11285
CNE: CNG00130
CNB: CNBG4610
TASA: A1Q1_01213
ABP: AGABI1DRAFT104926(AGABI1DRAFT_104926)
ABV: AGABI2DRAFT183659(AGABI2DRAFT_183659)
MGL: MGL_1338
MRT: MRET_4025
KPR: KPR_2432
EAE: EAE_19500
EAR: CCG29985
KQV: B8P98_13560(tenA)
RTG: NCTC13098_03722(tenA)
CLAP: NCTC11466_01594(tenA)
EBF: D782_2178
SMAR: SM39_2621
SPE: Spro_3122
SPLY: Q5A_016320(tenA)
SERF: L085_12735
SQU: E4343_00405(tenA)
SFJ: SAMEA4384070_3184(tenA)
SOD: Sant_2375
EBI: EbC_03310(tenA) EbC_27190
ERWI: GN242_12150(tenA)
PAGG: AL522_01495(tenA)
PEY: EE896_18980(tenA)
HIN: HI0358
HIT: NTHI0476
HIU: HIB_04700
HIA: H733_0251
HIW: NTHI477_01400(tenA)
HIC: NTHIC486_00629(tenA)
HIX: NTHI723_01330(tenA)
HHZ: NCTC10839_00157(tenA)
HAEG: NCTC8502_00862(tenA)
HPAA: E5Q53_08790(tenA)
PMU: PM1264
PMV: PMCN06_1929(tenA)
PMP: Pmu_19250
PMUL: DR93_508(tenA)
PDAG: 4362423_01616(tenA)
APL: APL_0537
APJ: APJL_0528
APA: APP7_0577
ADP: NCTC12871_01351(tenA)
ALIG: NCTC10568_01004(tenA)
ASEG: NCTC10977_00108(tenA)
APAG: EIA51_04660(tenA)
AVT: NCTC3438_01115(tenA)
RPNE: NCTC8284_01798(tenA)
PAET: NCTC13378_01119(tenA)
VPA: VPA0132
VAG: N646_3565
VDB: AL552_02640(tenA)
VHR: AL538_20285(tenA)
VSP: VS_II1086
VTA: B0310
VAF: D1115_16070(tenA)
VNL: D3H41_22015(tenA)
VCC: FAZ90_20360(tenA)
VAS: GT360_09520(tenA)
VFI: VF_A0320
PPR: PBPRB0684(NCU07849)
PPU: PP_3186
ACB: A1S_3290
ABM: ABSDF3398
ABY: ABAYE0200
ABN: AB57_3737
ABB: ABBFA_00190(tenA)
ABX: ABK1_3536
ABZ: ABZJ_04180(tenA)
ABH: M3Q_23
ABAD: ABD1_31850
ABAZ: P795_0975
ABAU: IX87_13455
ABAA: IX88_01230
ACC: BDGL_002754(thiED)
ACI: ACIAD3452
AID: CTZ23_00830(tenA)
ADV: DJ533_03625(tenA)
ARJ: DOM24_13545(tenA)
AWU: BEN71_01540(tenA)
ACUM: C9E88_005115(tenA)
AGU: AS4_01950
AUG: URS_1249
ALW: FOB21_10825(tenA)
ADS: FPL17_15315(tenA)
MAD: HP15_2778
GPS: C427_4772
PIN: Ping_2374
MVS: MVIS_1660
MMAA: FR932_04715(tenA)
RVI: RVIR1_06650(tenA)
LOK: Loa_01485
TMC: LMI_0190
FNA: OOM_0367
FRC: KX01_1693
SPIZ: GJ672_00555(tenA)
GAI: IMCC3135_03725(tenA_1) IMCC3135_19885(tenA_2)
HEL: HELO_3147
HAM: HALO3550
HCO: LOKO_02540(tenA_1) LOKO_03718(tenA_2)
HHH: CLM76_10855(tenA)
HBE: BEI_2561(tenA)
HAF: C8233_15460(tenA)
HALK: CUU95_01395(tenA)
HVN: EI420_04650(tenA)
HMD: CTT34_04690(tenA)
KUY: FY550_12265(tenA)
OCE: GU3_15145
NAQ: D0T90_09270(tenA)
BPK: BBK_1794
BUT: X994_3025
BGO: BM43_3456
LMIR: NCTC12852_00657(tenA_1) NCTC12852_02440(tenA_2)
BOZ: DBV39_16320(tenA)
AXX: ERS451415_05958(tenA)
ACHR: C2U31_03385(tenA)
OUR: CEQ07_02075(tenA)
CTES: O987_21130
MMS: mma_0874(tenA1) mma_0875(tenA2)
ATW: C0099_11985(tenA)
KSO: CKSOR_00579(tenA)
HPY: HP1287
HPJ: jhp_1207
HPL: HPB8_194(tenA)
HPZ: HPKB_1222
HPD: KHP_1182(tenA)
HEY: MWE_1495
HPYR: K747_04580
HPYI: K750_02030
HPYU: K751_01175
HPYM: K749_07345
HEB: U063_0319
HEZ: U064_0320
HCM: HCD_00505
CJE: Cj0440c
CJU: C8J_0415
CJI: CJSA_0412
CJM: CJM1_0424
CJS: CJS3_0429
CJEJ: N564_00421
CJEU: N565_00472
CJEN: N755_00470
CJEI: N135_00488
CJER: H730_02775
CJY: QZ67_00445(tenA)
CJQ: UC78_0424(tenA)
CJR: CJE0491
CLA: CLA_0284
CCQ: N149_0435(tenA)
CCF: YSQ_07675
CCOI: YSU_06685
CCOF: VC76_02295(tenA)
CCOO: ATE51_03338(tenA)
CCUN: CCUN_1350
CAVI: CAV_0384
ASK: EI285_00370(tenA)
ATP: ATR_0093
PACO: AACT_2231
SUR: STAUR_1071(tenA)
WOL: WD_0139
WCL: WCLE_002650(tenA) WCLE_005250(tenA)
RBT: NOVO_08600(tenA)
AGC: BSY240_70
RHT: NT26_3523
RJG: CCGE525_01865(tenA)
RAD: CO657_21705(tenA)
BME: BMEI1738
BMEL: DK63_1748(tenA)
BMEE: DK62_1204(tenA)
BMF: BAB1_0213
BABO: DK55_225(tenA)
BABR: DO74_1658(tenA)
BABT: DK49_2072(tenA)
BABB: DK48_1901(tenA)
BABU: DK53_218(tenA)
BABS: DK51_1244(tenA)
BABC: DO78_136(tenA)
BMS: BR0212
BSZ: DK67_2028(tenA)
BOV: BOV_0203
BCAR: DK60_311(tenA)
BCAS: DA85_01025
BMR: BMI_I215
BPP: BPI_I213
BPV: DK65_1161(tenA)
OAH: DR92_2445 DR92_29(tenA)
BJA: bll7388
BRS: S23_59930
BRAD: BF49_2905
BOT: CIT37_18265(tenA)
BRQ: CIT40_04545(tenA)
BGZ: XH91_29525(tenA)
BSYM: CIT39_02890(tenA)
BBET: F8237_09605(tenA)
NWI: Nwi_0858
VGO: GJW-30_1_01663(tenA)
AZC: AZC_1878
MDI: METDI5490
MEX: Mext_4454
MCH: Mchl_4918
MPO: Mpop_4968
MNO: Mnod_7784
MOR: MOC_3900
META: Y590_22710
MMES: MMSR116_12265(tenA)
BID: Bind_1209
PLEO: OHA_1_00322(tenA)
HDI: HDIA_2952(tenA)
RBM: TEF_11590
SIL: SPO0051
RUT: FIU92_07225(tenA1) FIU92_16205(tenA2)
RSP: RSP_3694
RDE: RD1_0753(tenA) RD1_0755(tenA) RD1_3613(tenA)
DSH: Dshi_0908
PSF: PSE_3005(tenA) PSE_4898(tenA)
LABT: FIU93_08530(tenA1) FIU93_20940(tenA2)
SPSE: SULPSESMR1_04966(tenA)
SDO: SD1155_00180(tenA)
LVS: LOKVESSMR4R_02489(tenA)
SAGU: CDO87_02870(tenA)
SEDI: EBB79_14500(tenA)
BOO: E2K80_07585(tenA)
ROT: FIV09_18995(tenA)
PAED: G5B38_06880(tenA)
MON: G8E03_12775(tenA)
MALU: KU6B_29660(thiED)
FAQ: G5B39_05560(tenA)
NOV: TQ38_016660(tenA)
SPHR: BSY17_3764(tenA)
SHYD: CJD35_17550(tenA)
RDI: CMV14_13060(tenA)
GDI: GDI2186
GDJ: Gdia_0406
GXY: GLX_25490
GXL: H845_491
KEU: S101446_02881(tenA)
KSC: CD178_00528(tenA)
KRE: GWK63_07895(tenA)
ROS: CTJ15_12210(tenA)
RMUC: FOB66_06990(tenA)
COQ: D9V35_06495(tenA)
COMM: GN303_06285(tenA)
RRU: Rru_A2025
RRF: F11_10415
RCE: RC1_1613
AZL: AZL_d02610(tenA)
AZM: DM194_22440(tenA)
AZZ: DEW08_27585(tenA)
MAGQ: MGMAQ_2630
NCB: C0V82_14920(tenA)
PGV: SL003B_2357(tenA)
BSU: BSU11650(tenA)
BSR: I33_1299
BSL: A7A1_0982
BSH: BSU6051_11650(tenA)
BSUT: BSUB_01267(tenA)
BSUL: BSUA_01267(tenA)
BSUS: Q433_06585
BSS: BSUW23_05890(tenA)
BST: GYO_1470
BSO: BSNT_07608(tenA)
BSQ: B657_11650(tenA)
BSX: C663_1193
BLI: BL01592(tenA) BL02647
BLD: BLi01259(tenA) BLi04205
BAY: RBAM_011660(tenA)
BAQ: BACAU_1127(tenA)
BYA: BANAU_1072(tenA)
BAMP: B938_05670
BAML: BAM5036_1066(tenA)
BAMA: RBAU_1128(tenA)
BAMN: BASU_1105(tenA)
BAMB: BAPNAU_2629(tenA)
BAMT: AJ82_06555
BAMY: V529_11140(tenA)
BMP: NG74_01180(tenA)
BAO: BAMF_1239(tenA)
BAZ: BAMTA208_11775(tenA)
BQL: LL3_01246(tenA)
BXH: BAXH7_02404(tenA)
BQY: MUS_1210(tenA)
BAMI: KSO_014010
BAMC: U471_11630
BAMF: U722_05945
BSIA: CWD84_15910(tenA)
BHT: DIC78_03750(tenA)
BAN: BA_0725 BA_2611(tenA)
BAR: GBAA_0725 GBAA_2611(tenA)
BAI: BAA_0832 BAA_2675(tenA)
BANV: DJ46_1394(tenA) DJ46_5205(tenA)
BCA: BCE_0795 BCE_2629(tenA)
BCZ: BCE33L0635(tenA) BCE33L2357(tenA)
BCQ: BCQ_0816(tenA) BCQ_2485(tenA)
BCX: BCA_0788 BCA_2702(tenA)
BAL: BACI_c07560(tenA1) BACI_c25910(tenA2)
BCF: bcf_03825
BCER: BCK_04510
BTK: BT9727_0635(tenA) BT9727_2391(tenA)
BTL: BALH_0661(tenA) BALH_2351
BTG: BTB_c08180(tenA1) BTB_c26650(tenA2)
BTW: BF38_1992(tenA) BF38_3793(tenA)
BWW: bwei_2306 bwei_4264(tenA)
BMYO: BG05_3304(tenA) BG05_5176(tenA)
BMYC: DJ92_3336(tenA) DJ92_5200(tenA)
BWD: CT694_04160(tenA) CT694_13745(tenA)
BTRO: FJR70_06195(tenA) FJR70_26035(tenA)
BMEG: BG04_3180(tenA) BG04_4450(tenA)
BCK: BCO26_0615(tenA)
BAG: Bcoa_0561
BCOA: BF29_3129(tenA)
BJS: MY9_1270
BACP: SB24_04040
BACB: OY17_08530
BACO: OXB_2219
BACY: QF06_04775
BACL: BS34A_12880(tenA)
BALM: BsLM_1219
BBEV: BBEV_2609(tenA)
BALT: CFN77_05810(tenA) CFN77_18870(tenA)
BTHV: CQJ30_02205(tenA)
BCIR: C2I06_17490(tenA)
BHA: BH2679(tenA)
BCL: ABC0669(tenA) ABC0756
BPF: BpOF4_13155(tenA)
BKW: BkAM31D_11685(tenA)
BKO: CKF48_20480(tenA)
OCN: CUC15_00840(tenA) CUC15_02440(tenA)
GKA: GK0618
GGH: GHH_c05710(tenA)
GEA: GARCT_00592(tenA)
PTB: DER53_07610(tenA)
AFL: Aflv_2320(tenA)
ANM: GFC28_1939(tenA)
ANL: GFC29_3495(tenA)
AND: GRQ40_03555(tenA)
AXL: AXY_04970(tenA)
HHD: HBHAL_4925(tenA)
HLI: HLI_13310(tenA)
VIL: CFK37_04690(tenA)
VNE: CFK40_00190(tenA)
VPN: A21D_00402(tenA_1) A21D_01435(tenA_2)
VIM: GWK91_05250(tenA)
AQT: FN924_13125(tenA)
PSYH: D0S48_16405(tenA)
GRC: GI584_02925(tenA) GI584_06380(tenA)
RUE: DT065_09215(tenA) DT065_13830(tenA) DT065_18035(tenA)
SALE: EPH95_14095(tenA)
POF: GS400_16485(tenA)
NMK: CHR53_11470(tenA)
NTM: BTDUT50_04310(tenA)
STEA: C0679_09145(tenA)
BSE: Bsel_2597
SAU: SA1897
SAV: SAV2094
SAW: SAHV_2079
SAM: MW2017
SAS: SAS1998
SAR: SAR2183(tenA)
SAC: SACOL2086
SAE: NWMN_1998
SAD: SAAV_2148
SUU: M013TW_2052(tenA)
SUE: SAOV_2135c(tenA)
SUJ: SAA6159_02008(tenA)
SUK: SAA6008_02132(tenA)
SUZ: MS7_2110(tenA)
SUX: SAEMRSA15_20030(tenA)
SUW: SATW20_22330(tenA)
SUG: SAPIG2137
SUF: SARLGA251_18960(tenA)
SAUA: SAAG_02307
SAUE: RSAU_001933(tenA)
SAUS: SA40_1851(tenA)
SAUU: SA957_1935(tenA)
SAUG: SA268_2006(tenA)
SAUZ: SAZ172_2198(tenA)
SAUT: SAI1T1_2015440(tenA)
SAUJ: SAI2T2_1015450(tenA)
SAUK: SAI3T3_1015440(tenA)
SAUQ: SAI4T8_1015450(tenA)
SAUF: X998_2073(tenA)
SAB: SAB1978c(tenA)
SUY: SA2981_2035(tenA)
SAUB: C248_2107(tenA)
SAUC: CA347_2174(tenA)
SAUR: SABB_02420(tenA)
SAUI: AZ30_11070
SAUD: CH52_08485
SAMS: NI36_10250
SER: SERP1701
SEP: SE1693
SEPP: SEB_01704
SEPS: DP17_637(tenA)
SHA: SH0940(tenA)
SHH: ShL2_00831(tenA)
SSP: SSP0789
SCA: SCA_1596(tenA) SCA_2227
SLN: SLUG_09710(tenA)
SDT: SPSE_0455 SPSE_0732(tenA)
SPAS: STP1_0529
SXO: SXYL_00838(tenA)
SHU: SHYC_03810(tenA)
SCAP: AYP1020_1281(tenA)
SAGQ: EP23_06260(tenA)
SSIF: AL483_01895(tenA) AL483_11330(tenA)
SPET: CEP67_04455(tenA)
SSCU: CEP64_00705(tenA)
SKL: C7J89_05500(tenA)
SFQ: C7J90_00150(tenA) C7J90_05290(tenA)
SHOM: EGX58_08150(tenA)
SMUS: C7J88_05960(tenA)
SCAR: DWB96_04200(tenA)
SFF: FOB90_04125(tenA) FOB90_05340(tenA)
SDP: NCTC12225_00530(tenA_1) NCTC12225_00800(tenA_2)
SCHR: DWB92_03630(tenA)
MCL: MCCL_0787(tenA) MCCL_1749
MCAK: MCCS_22600(tenA)
LMO: lmo0315
LMOB: BN419_0358
LMOD: LMON_0323
LMOW: AX10_10135
LMOM: IJ09_08720
LMOG: BN389_03360(tenA)
LMP: MUO_01750
LMOZ: LM1816_05383(tenA)
LMOX: AX24_14350
LMQ: LMM7_0345(tenA)
LMS: LMLG_0735
LMOK: CQ02_01745
LMV: Y193_14215(tenA)
LIN: lin0340
LWE: lwe0286
LGZ: NCTC10812_00606(tenA)
BTHS: CNY62_04410(tenA)
ESI: Exig_0935
EAN: Eab7_0906
GMO: NCTC11323_00418(tenA_1) NCTC11323_01367(tenA_2)
GEQ: CG018_04060(tenA)
GSA: FOC50_06465(tenA)
GHA: NCTC10459_01387(tenA)
BBE: BBR47_31010(tenA)
BAGR: BA6348_14710(tenA)
BRW: GOP56_06620(tenA)
PPY: PPE_03732
PPM: PPSC2_19700(tenA)
PPO: PPM_3946(tenA)
PPOL: X809_35795
PPQ: PPSQR21_039730(tenA)
PPOY: RE92_17565
PLW: D5F53_24010(tenA)
PLEN: EIM92_21805(tenA)
PLUT: EI981_05255(tenA)
PALB: EJC50_16700(tenA)
ASOC: CB4_04181(tenA)
SACA: FFV09_16040(tenA)
AAC: Aaci_1931
AAD: TC41_2031(tenA)
TAB: CIG75_04580(tenA)
SIV: SSIL_1334
SOB: CSE16_03505(tenA)
PLX: CW734_13975(tenA)
JEO: JMA_10710
KUR: ASO14_1761(tenA)
KZO: NCTC404_01948(tenA)
SPOS: DV702_12030(tenA)
SPAE: E2C16_01845(tenA)
PANC: E2636_03155(tenA) E2636_03660(tenA)
PGQ: FK545_05150(tenA)
PLAY: DNR44_003955(tenA)
KPUL: GXN76_06390(tenA)
KEB: GXN75_05655(tenA)
LLA: L0228(tenA)
LLK: LLKF_1951(tenA)
LLT: CVCAS_1711(tenA)
LLS: lilo_1761(tenA)
LLD: P620_10060(tenA)
LLX: NCDO2118_1886(tenA)
LLM: llmg_1961(tenA)
LLC: LACR_1950
LLR: llh_3495
LLI: uc509_1733(tenA)
LLW: kw2_1757
LLJ: LG36_1734(tenA)
SPN: SP_0722(tenA)
SPD: SPD_0622 SPD_0628(tenA)
SPR: spr0628 spr0634(tenA)
SPW: SPCG_0664 SPCG_0671(tenA)
SPP: SPP_0733
SAG: SAG0839
SAN: gbs0857
SAK: SAK_0962
SGC: A964_0842(tenA)
SAGM: BSA_9270
SAGR: SAIL_9830
SAGP: V193_03980
SAGC: DN94_03980
SAGE: EN72_04930
SAGG: EN73_04630
SAGN: W903_0929(tenA)
SGA: GALLO_1181(tenA)
SGG: SGGBAA2069_c11710(tenA)
SGT: SGGB_1175(tenA)
SOR: SOR_1405(tenA) SOR_1409
STB: SGPB_1039(tenA)
SIF: Sinf_1014(tenA)
STRN: SNAG_1373(tenA_1) SNAG_1377(tenA_2)
LSA: LCA_1095
LBR: LVIS_1830
LCA: LSEI_0297
LCS: LCBD_0314(theD)
LCE: LC2W_0306(theD)
LPAP: LBPC_0301
LCB: LCABL_03130(tenA)
LCW: BN194_03180(tenA)
LFE: LAF_0359
LRH: LGG_00366(tenA)
LRG: LRHM_0354
LRL: LC705_00355(tenA)
LRA: LRHK_366
LKL: DKL58_08825(tenA)
PPE: PEPE_0561
PPEN: T256_03060
PCE: PECL_1555
EFA: EF2767
EFL: EF62_2919(tenA)
EFI: OG1RF_12127(tenA)
EFS: EFS1_2231
EFN: DENG_02711(tenA)
EFQ: DR75_1459(tenA)
ENE: ENT_19320
EHR: EHR_13955
EAV: EH197_13895(tenA)
MPS: MPTP_0977
MPX: MPD5_0967
OSI: DLJ48_07000(tenA)
LME: LEUM_1546
LMM: MI1_06925
LCI: LCK_01393
LGS: LEGAS_0465(tenA)
WKO: WKK_02270
WCE: WS08_0578
WCT: WS74_0579
WSO: WSWS_00350(tenA)
CARN: FPV25_06725(tenA)
DPM: FNV33_01480(tenA) FNV33_08090(tenA)
CPE: CPE2546
CPF: CPF_2870(tenA)
CBK: CLL_A1417
CBN: CbC4_0598
CBT: CLH_1337
CBE: Cbei_2088
CBZ: Cbs_2088
CBEI: LF65_02399
CBV: U729_163(tenA)
CSQ: CSCA_2523
CSEP: CP523_12875(tenA)
CDY: F3K33_10420(tenA)
RCH: RUM_01540
FPA: FPR_28330
CCT: CC1_13460
CSO: CLS_07220
CPRO: CPRO_00820(tenA)
ROC: HF520_05240(tenA)
OVA: OBV_30950
OBJ: EIO64_01180(tenA)
SAY: TPY_3620(tenA)
BPRS: CK3_22260
CAD: Curi_c17920(tenA)
LPIL: LIP_2298
SMIR: SMM_0102(tenA)
SMIA: P344_00620
MMC: Mmcs_0357
MKM: Mkms_0367
MJL: Mjls_0346
MGRO: FZ046_20620(tenA)
MVA: Mvan_2973
MGI: Mflv_3256
MPHL: MPHLCCUG_05136(tenA)
MVQ: MYVA_3103
MTHN: 4412656_02365(tenA)
MHAS: MHAS_04309(tenA)
MTER: 4434518_02680(tenA)
MMIN: MMIN_04290
ASD: AS9A_2937
CVA: CVAR_2054
CTER: A606_08230
NFA: NFA_14600
NFR: ERS450000_02659(tenA)
ROP: ROP_13010
REQ: REQ_15870
RFA: A3L23_03222(tenA)
RHU: A3Q40_00755(tenA)
GOR: KTR9_3809
SMAL: SMALA_8083
KSK: KSE_39800
STRI: C7M71_015785(tenA)
ARR: ARUE_c04760(tenA)
AAU: AAur_0504
RSA: RSal33209_3250(tenA)
DCO: SAMEA4475696_0004(tenA)
PAC: PPA1507
PACC: PAC1_07935
PACH: PAGK_0671
CACN: RN83_08000
PFR: PFREUD_12090(tenA)
PFRE: RM25_0982
PAUS: NCTC13651_02140(tenA)
KFL: Kfla_2096
TFU: Tfu_2953
NDA: Ndas_5262
NAL: B005_1899
STRR: EKD16_00400(tenA)
TCU: Tcur_0089
FAL: FRAAL1555
GOB: Gobs_0097
KRA: Krad_0855
AMYY: YIM_00930(tenA)
PDX: Psed_5477
ACTI: UA75_11055
ACAD: UA74_10965
AHG: AHOG_10310(tenA)
ACTA: C1701_23515(tenA)
BLO: BL0804
BLN: Blon_1460
BLON: BLIJ_1506
BAD: BAD_0874
BLA: BLA_1213(tenA)
BBB: BIF_00231
BBC: BLC1_0658
BLV: BalV_0662
BLW: W7Y_0689
BLS: W91_0712
BANI: Bl12_0642
BANL: BLAC_03445
BANM: EN10_03485
BDE: BDP_1341(tenA) BDP_2140(tenA)
BBRU: Bbr_0964(tenA)
BBRE: B12L_0881
BBRV: B689b_0975
BBRJ: B7017_1028
BBRC: B7019_1037
BBRN: B2258_0927
BBRS: BS27_0961(tenA)
BBRD: BBBR_0912
BTP: D805_1323
BCAT: BBCT_1070
BPSP: AH67_03755
BANG: BBAG_1081
BGX: ESN35_07170(tenA)
GVG: HMPREF0421_21010(pet)
SIJ: SCIP_1237
RXY: Rxyl_2784
CWO: Cwoe_5519
SYC: syc0455_d(tenA)
CYA: CYA_0413
CYB: CYB_2439
LET: O77CONTIG1_02036(tenA)
HHG: XM38_023390(tenA_2)
PMM: PMM0357
PRC: EW14_0412
MAR: MAE_47490
MPK: VL20_3400
TER: Tery_0805
OXY: HCG48_22550(tenA)
ANA: alr2769
NSH: GXM_02039
AVA: Ava_0021
CTHE: Chro_2842
RCA: Rcas_1431
CAU: Caur_0797
HAU: Haur_2439
TRO: trd_0539
STI: Sthe_3424
KBS: EPA93_18350(tenA)
PUV: PUV_24790
PSL: Psta_0416
IPA: Isop_2016
LBF: LBF_0933
BHY: BHWA1_02511(tenA)
BRM: Bmur_2169
BPO: BP951000_0072(tenA)
BPW: WESB_1504
BIP: Bint_0735(tenA)
BTH: BT_3146
PSAC: PSM36_1775
DYS: G7050_04640(tenA)
SRU: SRU_0332
SRM: SRM_00411(tenA)
ARAC: E0W69_005535(tenA)
FLN: FLA_1147
SMIZ: 4412673_02700(tenA)
SPDR: G6053_09200(tenA)
SDJ: NCTC13534_03798(tenA)
EST: DN752_07620(tenA)
ECHI: FKX85_01045(tenA)
DFE: Dfer_4829
SLI: Slin_3497
SPIR: CWM47_08800(tenA)
SPIK: EXU85_27075(tenA)
LBY: Lbys_0380
FLM: MY04_2382(tenA)
CHK: D4L85_13540(tenA)
FSE: DI487_11115(tenA)
ZPR: ZPR_1973
MARM: YQ22_17205
EAO: BD94_1110
ELB: VO54_01429(tenA)
ELZ: FCS00_04900(tenA)
CHZ: CHSO_1188
CIO: CEQ15_22995(tenA)
CHRY: CEY12_19105(tenA)
CPIP: CJF12_09725(tenA)
CARH: EGY05_02545(tenA)
CNK: EG343_19060(tenA)
OAQ: DZC78_04715(tenA)
EMAR: D1013_10075(tenA)
EBV: F0358_01945(tenA)
CTS: Ctha_0667
NDE: NIDE1200
NJA: NSJP_2178
TVO: TVG0084143(TVG0084143)
PTO: PTO1258
FAI: FAD_0325
PFU: PF1338
PFI: PFC_05905
PHO: PH1161(PH1161)
PAB: PAB1641
PYN: PNA2_1769
PYS: Py04_0940
TSI: TSIB_0466
HHB: Hhub_4094(tenA)
HSU: HLASF_1556(tenA)
HSF: HLASA_1543(tenA)
HMA: rrnAC1765(tenA) rrnAC1767(tenA-2)
HHI: HAH_2295(tenA) HAH_2296(tenA-2)
NPH: NP_4080A(tenA1) NP_4082A(tenA2)
NMO: Nmlp_1839(tenA1) Nmlp_2310(tenA2)
HWA: HQ_2369A(tenA)
HWC: Hqrw_2630(tenA)
HVO: HVO_B0380(tenA1) HVO_B0381(tenA2)
HME: HFX_5295(tenA-2) HFX_5296(tenA)
HRA: EI982_05880(tenA)
HLM: DV707_08690(tenA)
HALB: EKH57_06505(tenA)
HEZZ: EO776_05995(tenA)
HTU: Htur_2707
NMG: Nmag_0869(tenA)
NAT: NJ7G_3269
NVR: FEJ81_11735(tenA)
NPL: FGF80_10845(tenA)
NBG: DV706_10485(tenA)
NAS: GCU68_01570(tenA)
APE: APE_0669.1(tenA)
ACJ: ACAM_0495(tenA)
SMR: Smar_0054
SSO: SSO2598(tenA-2)
SSOA: SULA_0023 SULA_0402(tenA)
SSOL: SULB_0024 SULB_0404(tenA)
SSOF: SULC_0023 SULC_0402(tenA)
SAI: Saci_1230
MSE: Msed_1351
MCN: Mcup_0881
MHK: DFR87_12335(tenA)
MPRU: DFR88_11570(tenA)
MTEN: GWK48_00570(tenA)
ABRI: DFR85_05590(tenA)
PAI: PAE0170
PIS: Pisl_1974
PCL: Pcal_1316
PAS: Pars_2186
PYR: P186_0930
POG: Pogu_2702
TNE: Tneu_1074
CMA: Cmaq_0480
TTN: TTX_0325(tenA)
TUZ: TUZN_0831
ASC: ASAC_0493
CCAI: NAS2_0629
 » show all
Reference
1  [PMID:13243520]
  Authors
FUJITA A, NOSE Y, KURATANIK.
  Title
The second type of bacterial thiaminase.
  Journal
J Vitaminol (Kyoto) 1:1-7 (1954)
DOI:10.5925/jnsv1954.1.1
Reference
2
  Authors
Ikehata, H.
  Title
Purification of thiaminase II.
  Journal
J Gen Appl Microbiol 6:30-39 (1960)
Reference
3  [PMID:15709744]
  Authors
Toms AV, Haas AL, Park JH, Begley TP, Ealick SE
  Title
Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
  Journal
Biochemistry 44:2319-29 (2005)
DOI:10.1021/bi0478648
  Sequence
[bsu:BSU11650]
Reference
4  [PMID:15858269]
  Authors
Benach J, Edstrom WC, Lee I, Das K, Cooper B, Xiao R, Liu J, Rost B, Acton TB, Montelione GT, Hunt JF
  Title
The 2.35 A structure of the TenA homolog from Pyrococcus furiosus supports an enzymatic function in thiamine metabolism.
  Journal
Acta Crystallogr D Biol Crystallogr 61:589-98 (2005)
DOI:10.1107/S0907444905005147
Reference
5  [PMID:17618314]
  Authors
Jenkins AH, Schyns G, Potot S, Sun G, Begley TP
  Title
A new thiamin salvage pathway.
  Journal
Nat Chem Biol 3:492-7 (2007)
DOI:10.1038/nchembio.2007.13
Reference
6  [PMID:18054064]
  Authors
Jenkins AL, Zhang Y, Ealick SE, Begley TP
  Title
Mutagenesis studies on TenA: a thiamin salvage enzyme from Bacillus subtilis.
  Journal
Bioorg Chem 36:29-32 (2008)
DOI:10.1016/j.bioorg.2007.10.005
  Sequence
[bsu:BSU11650]
Reference
7  [PMID:21904031]
  Authors
French JB, Begley TP, Ealick SE
  Title
Structure of trifunctional THI20 from yeast.
  Journal
Acta Crystallogr D Biol Crystallogr 67:784-91 (2011)
DOI:10.1107/S0907444911024814
  Sequence
[sce:YOL055C]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.99.2
IUBMB Enzyme Nomenclature: 3.5.99.2
ExPASy - ENZYME nomenclature database: 3.5.99.2
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.99.2
BRENDA, the Enzyme Database: 3.5.99.2
CAS: 9024-80-0

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