KEGG   ENZYME: 3.6.1.28
Entry
EC 3.6.1.28                 Enzyme                                 
Name
thiamine-triphosphatase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
thiamine-triphosphate phosphohydrolase
Reaction(IUBMB)
thiamine triphosphate + H2O = thiamine diphosphate + phosphate [RN:R00618]
Reaction(KEGG)
R00618
Substrate
thiamine triphosphate [CPD:C03028];
H2O [CPD:C00001]
Product
thiamine diphosphate [CPD:C00068];
phosphate [CPD:C00009]
History
EC 3.6.1.28 created 1978
Pathway
ec00730  Thiamine metabolism
ec01100  Metabolic pathways
Orthology
K05307  thiamine-triphosphatase
Genes
HSA79178(THTPA)
PTR745282(THTPA)
PPS100977058(THTPA)
GGO101139989(THTPA)
PON100173227(THTPA)
NLE100603625(THTPA)
HMH116456227(THTPA)
MCC714403(THTPA)
MCF102122817(THTPA)
MTHB126958245
MNI105499590(THTPA)
CSAB103231484(THTPA)
CATY105598755(THTPA)
PANU101007810(THTPA)
TGE112628497(THTPA)
MLEU105547200(THTPA)
RRO104664867(THTPA)
RBB108523593(THTPA)
TFN117069953(THTPA)
PTEH111554741(THTPA)
CANG105503755(THTPA)
CJC100401156(THTPA)
SBQ101030701(THTPA)
CIMI108315358(THTPA)
CSYR103270241(THTPA)
MMUR105864724(THTPA)
LCAT123620236(THTPA)
PCOQ105814439(THTPA)
OGA100965363(THTPA)
MMU105663(Thtpa)
MCAL110309218(Thtpa)
MPAH110325225(Thtpa)
RNO305889(Thtpa)
MCOC116085345(Thtpa)
ANU117705901(Thtpa)
MUN110566649(Thtpa)
CGE100764351(Thtpa)
MAUA101831628(Thtpa)
PROB127230395(Thtpa)
PLEU114708766(Thtpa)
MORG121434861(Thtpa)
MFOT126490881
AAMP119800159(Thtpa)
NGI103739450(Thtpa)
HGL101709464(Thtpa)
CPOC100725495(Thtpa)
CCAN109696809(Thtpa)
DORD105992531(Thtpa)
DSP122113405(Thtpa)
PLOP125363506(Thtpa)
NCAR124976658
MMMA107147931(Thtpa)
OCU100346906
OPI101535204(THTPA)
TUP102485835(THTPA)
GVR103585590(THTPA)
CFA490614(THTPA)
CLUD112657498(THTPA)
VVP112926524(THTPA)
VLG121493113(THTPA)
NPO129499481(THTPA)
AML100469428(THTPA)
UMR103681052(THTPA)
UAH113246055(THTPA)
UAR123795769(THTPA)
ELK111160872
LLV125104932
MPUF101672712(THTPA)
MNP131999821(THTPA)
MLK131836374(THTPA)
NVS122894426(THTPA)
ORO101384998(THTPA)
EJU114217876(THTPA)
ZCA113910573(THTPA)
MLX118003159(THTPA)
NSU110585232(THTPA)
LWW102742690(THTPA)
FCA101097247(THTPA)
PYU121031529(THTPA)
PCOO112856160(THTPA)
PBG122468907(THTPA)
PVIV125167664(THTPA)
LRUF124508831
PTG102950075(THTPA)
PPAD109255014(THTPA)
PUC125909673
AJU106979466
HHV120247041(THTPA)
BTA282090(THTPA)
BOM102275290(THTPA)
BIU109564793(THTPA)
BBUB102416479(THTPA)
BBIS104982014(THTPA)
CHX100860962(THTPA)
OAS101119565(THTPA)
BTAX128053874(THTPA)
ODA120853449(THTPA)
CCAD122443189(THTPA)
MBEZ129562809(THTPA)
SSC396635(THTPA)
CFR102515543(THTPA)
CBAI105068790(THTPA)
CDK105102404(THTPA)
VPC102534723(THTPA)
BACU103016436(THTPA)
BMUS118889639(THTPA)
LVE103069060(THTPA)
OOR101276979(THTPA)
DLE111164125(THTPA)
PCAD102974599(THTPA)
PSIU116749025(THTPA)
NASI112405009(THTPA)
ECB100052214(THTPA)
EPZ103563006(THTPA)
EAI106840632(THTPA)
MYB102247331(THTPA)
MYD102759266(THTPA)
MMYO118679025(THTPA)
MLF102441243(THTPA)
PKL118725460(THTPA)
EFUS103301503(THTPA)
MNA107531712(THTPA)
DRO112301268(THTPA)
SHON118980924(THTPA)
AJM119037222(THTPA)
PDIC114493108(THTPA)
PHAS123820396(THTPA)
MMF118632732(THTPA)
PPAM129074146(THTPA)
HAI109393637(THTPA)
RFQ117023252(THTPA)
PALE102878744(THTPA)
PGIG120593443(THTPA)
PVP105300552(THTPA)
RAY107497992(THTPA)
MJV108386862(THTPA)
TOD119238936(THTPA)
SARA101558064(THTPA)
SETR126001215(THTPA)
LAV100675702(THTPA)
TMU101341633
ETF101638964(THTPA)
DNM101433271(THTPA)
MDO100030627(THTPA)
GAS123237982(THTPA)
SHR100927206(THTPA)
AFZ127551068
PCW110194270(THTPA)
OAA100090555(THTPA)
CLV102086719(THTPA)
ASN102383746(THTPA)
AMJ102562068(THTPA)
CCAY125622101(THTPA)
DCC119842302(THTPA)
CPIC101954166(THTPA)
MRV120380528(THTPA)
ACS100554076(thtpa)
ASAO132779302(THTPA)
PVT110087822(THTPA)
SUND121935168(THTPA)
PBI103058184(THTPA)
PMUR107293102(THTPA)
CTIG120305791(THTPA)
PGUT117658206(THTPA)
APRI131197327(THTPA)
PTEX113448766(THTPA)
NSS113422272(THTPA)
VKO123018631(THTPA)
PMUA114583614(THTPA)
PRAF128400608(THTPA)
ZVI118094976(THTPA)
HCG128330570(THTPA)
GJA107117786(THTPA)
STOW125445063(THTPA)
EMC129338604(THTPA)
XLA108714869(thtpa.L) 734744(thtpa.S)
XTR100037895(thtpa)
NPR108786769(THTPA)
RTEM120941158(THTPA)
BBUF120991480(THTPA)
BGAR122933144(THTPA)
MUO115457337(THTPA) 115474239 115474853
GSH117361226(THTPA)
DRE100048920(thtpa)
SRX107735920 107758807
SANH107657808 107693802
SGH107580794 107581151
CCAR109049754
CAUA113042304(thtpa)
CGIB128013152
PTET122329529(thtpa)
LROH127155413(thtpa)
OMC131533678(thtpa)
PPRM120475915(thtpa)
RKG130087681(thtpa)
MAMB125258397(thtpa)
CIDE127506388
MASI127434330
TROS130547138(thtpa)
TDW130413373(thtpa)
MANU129425692(thtpa)
IPU108256428
IFU128599819(thtpa)
PHYP113541134(thtpa)
SMEO124375396(thtpa)
TFD113660537(thtpa)
TVC132840136(thtpa)
TRN134301180(thtpa)
AMEX103032820(thtpa)
CMAO118798649(thtpa)
EEE113586085(thtpa)
CHAR122130370(thtpa)
TRU101073828(thtpa)
TFS130513495(thtpa)
TNGGSTEN00009631G001
LCO109136786(thtpa)
NCC104941948(thtpa)
TBEN117484108(thtpa)
CGOB115025511(thtpa)
PGEO117465735(thtpa)
GACU117543654(thtpa)
EMAC134883813(thtpa)
ELY117264567(thtpa)
EFO125881476(thtpa)
PLEP121960386(thtpa)
SLUC116046297(thtpa)
ECRA117938189(thtpa)
ESP116672215(thtpa)
PFLV114549537(thtpa)
GAT120811686(thtpa)
PPUG119198367(thtpa)
AFB129110962(thtpa)
CLUM117749597(thtpa)
PSWI130206080(thtpa)
MSAM119907600(thtpa)
SCHU122867033(thtpa)
CUD121527015(thtpa)
ALAT119008601(thtpa)
MZE101465435(thtpa)
ONL100705726(thtpa)
OAU116312686(thtpa)
OLA101157256(thtpa)
OML112151313(thtpa)
CSAI133423219(thtpa)
XMA102238398(thtpa)
XCO114136552(thtpa)
XHE116711565(thtpa)
PRET103482317(thtpa)
PFOR103135322(thtpa)
PLAI106963437(thtpa)
PMEI106904901(thtpa)
GAF122824038(thtpa)
PPRL129364651(thtpa)
CVG107095243(thtpa)
CTUL119776939(thtpa)
GMU124858206(thtpa)
NFU107382696(thtpa)
KMR108245424(thtpa)
ALIM106529762(thtpa)
NWH119426335(thtpa)
AOCE111579353(thtpa)
MCEP124995403(thtpa)
CSEM103376930(thtpa)
POV109629488(thtpa)
SSEN122777282(thtpa)
HHIP117754227(thtpa)
HSP118098486(thtpa)
PPLT128426041(thtpa)
SMAU118290871(thtpa)
LCF108898229
SDU111239291(thtpa)
SLAL111648220(thtpa)
XGL120789735(thtpa)
HCQ109527880(thtpa)
SSCV125985756
PEE133396264(thtpa)
PTAO133470028(thtpa)
BPEC110166312(thtpa)
MALB109953009(thtpa)
BSPL114854634(thtpa)
SJO128382263(thtpa)
SASA100194700(thtpa)
STRU115195614(thtpa)
OTW112227818(thtpa)
OMY110489772(thtpa)
OGO124039658(thtpa)
ONE115130234(thtpa)
OKI109899353(thtpa)
OKE118371552(thtpa)
SALP111953958(thtpa)
SNH120051054(thtpa)
CCLU121570439(thtpa)
ELS105019498(thtpa)
SFM108927747(thtpa)
PKI111840716(thtpa)
AANG118224936(thtpa)
LOC107075960(thtpa)
PSPA121305166(thtpa)
PSEX120525285(thtpa)
LCM102354355(THTPA)
LERI129716218(thtpa)
PMRN116957952(THTPA)
LRJ133359723(THTPA)
BFO118418704
BBEL109479368
LPIC129254491
APLC110979990
SKO100376190
BCOO119072986
LSM121117421
DSV119437519
RSAN119399502
RMP119179694
CSCU111618297
LPOL106478228
PMEO129596006
HROHELRODRAFT_79038
LGILOTGIDRAFT_67883
PCAN112577409
BGT106060532 106072411
CVN111135418 111136628
CANU128189028
OSN115221044
LAK106159317
NVE5506847
EPA110248810
ATEN116297414
PDAM113665647
SPIS111342471
DGT114517735
MPPMICPUCDRAFT_50547(JGI:MicpuC2_50547)
CMECYME_CMI051C
CCPCHC_T00004517001
PANPODANSg426 PODANSg4750
PBELQC761_703040
PPSDQC762_703040
PPSPQC763_703040
PPSAQC764_703040
TTTTHITE_2010984
TRETRIREDRAFT_122499
TRRM419DRAFT_82308
AFVAFLA_004988
ALUCAKAW2_50141A AKAW2_50206S AKAW2_50421S
ABEARB_03139
TVETRV_07044
PNOSNOG_07908
BZECOCCADRAFT_112097
FFUCLAFUR5_04686
MBRMONBRDRAFT_30051
SMINv1.2.012291.t1(symbB.v1.2.012291.t1)
PTIPHATRDRAFT_37234
FCYFRACYDRAFT_239507
TPSTHAPSDRAFT_5797
EHXEMIHUDRAFT_453444 EMIHUDRAFT_458212
BGWVE98_C0001G0180
 » show all
Reference
1  [PMID:4335862]
  Authors
Hashitani Y, Cooper JR.
  Title
The partial purification of thiamine triphosphatase from rat brain.
  Journal
J Biol Chem 247:2117-9 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.28
IUBMB Enzyme Nomenclature: 3.6.1.28
ExPASy - ENZYME nomenclature database: 3.6.1.28
BRENDA, the Enzyme Database: 3.6.1.28
CAS: 9068-47-7

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