KEGG ENZYME: 3.6.1.58

ENZYME: 3.6.1.58

Entry

EC 3.6.1.58                 Enzyme

Name

8-oxo-dGDP phosphatase;
NUDT5;
MTH3 (gene name);
NUDT18

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

8-oxo-dGDP phosphohydrolase

Reaction(IUBMB)

(1) 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate [RN:R09877];
(2) 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate [RN:R12595]

Reaction(KEGG)

R09877 R12595

Substrate

8-oxo-dGDP [CPD:C20176];
H2O [CPD:C00001];
8-oxo-GDP [CPD:C22235]

Product

8-oxo-dGMP [CPD:C19968];
phosphate [CPD:C00009];
8-oxo-GMP [CPD:C22274]

Comment

The enzyme catalyses the hydrolysis of both 8-oxo-dGDP and 8-oxo-GDP thereby preventing translational errors caused by oxidative damage. The preferred in vivo substrate is not known. The enzyme does not degrade 8-oxo-dGTP and 8-oxo-GTP to the monophosphates (cf. EC 3.6.1.55, 8-oxo-dGTP diphosphatase) [1,2]. Ribonucleotide diphosphates and deoxyribonucleotide diphosphates are hydrolysed with broad specificity. The bifunctional enzyme NUDT5 also hydrolyses ADP-ribose to AMP and D-ribose 5-phosphate (cf. EC 3.6.1.13, ADP-ribose diphosphatase) [4]. The human enzyme NUDT18 also hydrolyses 8-oxo-dADP and 2-hydroxy-dADP, the latter at a slower rate [6].

History

EC 3.6.1.58 created 2012

Orthology

K01554

8-oxo-dGDP phosphatase

K13987

ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase

K17817

8-oxo-dGDP phosphatase

Genes

HSA:	11164(NUDT5) 79873(NUDT18)

PTR:	450306(NUDT5) 741929(NUDT18)

PPS:	100977496(NUDT18) 100977876(NUDT5)

GGO:	101132071(NUDT18) 101148720(NUDT5)

PON:	100172071(NUDT5) 100451093(NUDT18)

NLE:	100594282(NUDT18) 100600434(NUDT5)

HMH:	116459643 116461765(NUDT18) 116473662(NUDT5)

MCC:	694368(NUDT5) 707061(NUDT18)

MCF:	102118162(NUDT5) 102138807(NUDT18)

MTHB:

126961277 126962383

MNI:	105482153(NUDT18) 105490612(NUDT5)

CSAB:

103215715(NUDT18) 103237893(NUDT5)

CATY:

105579281(NUDT18) 105597392(NUDT5)

PANU:

101021881(NUDT18) 101022345(NUDT5)

TGE:	112630295(NUDT18) 112631906(NUDT5)

MLEU:

105531046(NUDT18) 105535746(NUDT5)

RRO:	104663986(NUDT18) 104664884(NUDT5)

RBB:	108521324(NUDT18) 108538530(NUDT5)

TFN:	117082492(NUDT5) 117093085(NUDT18)

PTEH:

111545674(NUDT18) 111550058(NUDT5)

CANG:

105506182(NUDT5) 105510205(NUDT18)

CJC:	100388611(NUDT18) 100414997(NUDT5)

SBQ:	101035792(NUDT5) 101041775(NUDT18)

CIMI:

108305277(NUDT5) 108318546(NUDT18)

CSYR:

103265921(NUDT18) 103267159(NUDT5)

MMUR:

105857132(NUDT18) 105871990(NUDT5)

LCAT:

123626393(NUDT18) 123626408(NUDT5)

PCOQ:

105823680(NUDT5) 105825244(NUDT18)

OGA:	100959416(NUDT5) 100962070(NUDT18)

MMU:	213484(Nudt18) 53893(Nudt5)

MCAL:

110289308(Nudt5) 110309407(Nudt18)

MPAH:

110325824(Nudt18) 110333951(Nudt5)

RNO:	361068(Nudt18) 361274(Nudt5)

MCOC:

116082462(Nudt5) 116085002(Nudt18)

ANU:	117704932(Nudt18) 117713638(Nudt5)

MUN:	110551659(Nudt18) 110560543(Nudt5)

CGE:	100765600(Nudt18) 100772118(Nudt5)

MAUA:

101839020(Nudt18) 101841022(Nudt5)

PROB:

127229849(Nudt5) 127230199(Nudt18)

PLEU:

114698779(Nudt18) 114708460(Nudt5)

MORG:

121432709(Nudt5) 121460157(Nudt18)

MFOT:

126506788

AAMP:

119800254(Nudt18) 119816502(Nudt5)

NGI:	103738702(Nudt5) 103747768(Nudt18)

HGL:	101710430(Nudt18) 101722031(Nudt5)

CPOC:

100723448(Nudt5) 100727909(Nudt18)

CCAN:

109682446(Nudt5) 109690459(Nudt18)

DORD:

105984516(Nudt5) 106002451(Nudt18)

DSP:	122096646(Nudt18) 122113110(Nudt5)

NCAR:

124962210 124983188

OCU:	100341885 100357274 127483571

OPI:	101517621(NUDT5) 101521574(NUDT18)

TUP:	102479208(NUDT18) 102481118(NUDT5)

GVR:	103590734(NUDT5) 103593958(NUDT18)

CFA:	478006(NUDT5) 609139(NUDT18)

CLUD:

112658935(NUDT5) 112669775(NUDT18)

VVP:	112926826(NUDT18) 112933374(NUDT5)

VLG:	121496791(NUDT18) 121496799(NUDT5)

AML:	100473859(NUDT18) 100482621(NUDT5)

UMR:	103673345(NUDT18) 103676270(NUDT5)

UAH:	113241068(NUDT5) 113270012(NUDT18)

UAR:	123777383(NUDT18) 123789983(NUDT5) 123800652

ELK:	111155612 111155669

LLV:	125092844 125107176

MPUF:

101679457(NUDT5) 101680100(NUDT18)

NVS:	122892207(NUDT5) 122919235(NUDT18)

ORO:	101364423(NUDT5) 101380890(NUDT18)

EJU:	114217534(NUDT18) 114217686(NUDT5)

ZCA:	113921435(NUDT5) 113925702(NUDT18)

MLX:	118021585(NUDT5) 118022069(NUDT18)

NSU:	110586462(NUDT5) 110588561(NUDT18)

LWW:	102735906(NUDT5) 102747900(NUDT18)

FCA:	101084635(NUDT5) 101090347(NUDT18)

PYU:	121014817(NUDT5) 121039889(NUDT18)

PBG:	122472413(NUDT5) 122472538(NUDT18)

LRUF:

124502270 124520257

PTG:	102950979(NUDT5) 102972039(NUDT18)

PPAD:

109273729(NUDT5) 109277362(NUDT18)

PUC:	125919987 125923318

AJU:	106971034(NUDT5) 106981091(NUDT18)

HHV:	120239491(NUDT18) 120241086(NUDT5)

BTA:	509535(NUDT18) 614149(NUDT5)

BOM:	102283030(NUDT5) 102284141(NUDT18)

BIU:	109562537(NUDT18) 109567873(NUDT5)

BBUB:

102412312(NUDT18) 102413034(NUDT5)

BBIS:

104992569(NUDT18) 104998762(NUDT5)

CHX:	102174220(NUDT5) 102178907(NUDT18)

OAS:	101117473(NUDT18) 101117779(NUDT5)

ODA:	120865372(NUDT18) 120869271(NUDT5)

CCAD:

122431830(NUDT18) 122448976(NUDT5)

SSC:	100156061(NUDT18) 100511529(NUDT5)

CFR:	102506081(NUDT5) 102521795(NUDT18)

CBAI:

105067997(NUDT5) 105069039(NUDT18)

CDK:	105100309(NUDT5) 105102746(NUDT18)

VPC:	102525025(NUDT18) 102526636(NUDT5)

BACU:

103014516(NUDT5) 103015615(NUDT18)

LVE:	103088541(NUDT5) 103089589(NUDT18)

OOR:	101271940(NUDT5) 101288904(NUDT18)

DLE:	111168994(NUDT18) 111178004(NUDT5)

PCAD:

102986174(NUDT5) 102992845(NUDT18)

PSIU:

116749766(NUDT5) 116755551(NUDT18)

ECB:	100056631(NUDT18) 100056812(NUDT5)

EPZ:	103563355(NUDT5) 103566265(NUDT18)

EAI:	106836935(NUDT5) 106847697(NUDT18)

MYB:	102243782(NUDT5) 102258993(NUDT18)

MYD:	102755333(NUDT5) 102755914(NUDT18)

MMYO:

118658996(NUDT18) 118677371(NUDT5)

MLF:	102417442(NUDT18) 102418798(NUDT5)

MNA:	107530244(NUDT5) 107543538(NUDT18)

PKL:	118725842(NUDT18) 118727251(NUDT5)

HAI:	109382362(NUDT18) 109390483(NUDT5)

DRO:	112305265(NUDT18) 112322673(NUDT5)

SHON:

118975193(NUDT18) 119000849(NUDT5)

AJM:	119054682(NUDT18) 119056687(NUDT5)

PDIC:

114491306(NUDT5) 114503091(NUDT18)

PHAS:

123828335(NUDT18) 123831123(NUDT5)

MMF:	118615257(NUDT5) 118615583(NUDT18) 118632073

RFQ:	117012780 117019138(NUDT5) 117038545(NUDT18)

PALE:

102895562(NUDT5) 102895707(NUDT18)

PGIG:

120606616(NUDT18) 120614600(NUDT5)

PVP:	105291704(NUDT5) 105296543(NUDT18)

RAY:	107504857(NUDT5) 107509238(NUDT18)

MJV:	108393187(NUDT18) 108395803(NUDT5)

TOD:	119233428(NUDT18) 119244686(NUDT5)

SARA:

101550425(NUDT18) 101557689(NUDT5)

LAV:	100675481(NUDT18) 100677273(NUDT5)

TMU:	101350654 101357650

ETF:	101650869(NUDT18) 101657037(NUDT5)

DNM:	101415921(NUDT5) 101442918(NUDT18)

MDO:	100013664(NUDT5) 100033092(NUDT18)

GAS:	123236963(NUDT18) 123249109(NUDT5)

SHR:	100913469(NUDT18) 100926504(NUDT5)

AFZ:	127537985 127548314

PCW:	110200406(NUDT18) 110217340(NUDT5)

OAA:	100084986(NUDT5) 100087230(NUDT18)

GGA:	426368(NUDT5)

PCOC:

116242624(NUDT5)

MGP:	100538350(NUDT5)

CJO:	107317497(NUDT5)

NMEL:

110391841(NUDT18) 110392265(NUDT5)

APLA:

101792445(NUDT5)

ACYG:

106046205(NUDT5)

AFUL:

116491303(NUDT5)

TGU:	100227819(NUDT5)

LSR:	110470929(NUDT5) 110479415(NUDT18)

SCAN:

103813570(NUDT5)

PMOA:

120497175(NUDT18) 120512495(NUDT5)

OTC:	121340597(NUDT5) 121346746(NUDT18)

PRUF:

121362338(NUDT5) 121366016(NUDT18)

GFR:	102042579(NUDT5)

FAB:	101811306(NUDT5)

PHI:	102100920(NUDT5) 102114450(NUDT18)

PMAJ:

107204378(NUDT5) 107213979(NUDT18)

CCAE:

111923119(NUDT5)

CCW:	104694502(NUDT5) 120411153(NUDT18)

CBRC:

103619809(NUDT5)

ETL:	114066636(NUDT5) 114072158(NUDT18)

ZAB:	102070954(NUDT5)

ACHL:

103805777(NUDT5)

SVG:	106857184(NUDT5) 106863455(NUDT18)

FPG:	101911346(NUDT5) 101919411(NUDT18)

FCH:	102050796(NUDT18) 102058952(NUDT5)

CLV:	102084865(NUDT5) 102095789(NUDT18)

EGZ:	104135774(NUDT5)

NNI:	104014621(NUDT5)

PLET:

104619219(NUDT5)

PCRI:

104035604(NUDT5)

PCAO:

104050308(NUDT5)

ACUN:

113475952(NUDT5)

TALA:

104367680(NUDT5) 116962929(NUDT18)

PADL:

103915005(NUDT5)

AFOR:

103904125(NUDT5)

ACHC:

115342293(NUDT5) 115350395(NUDT18)

HALD:

104316752(NUDT5)

HLE:	104828831(NUDT18) 104840201(NUDT5)

AGEN:

126044586 126051436

GCL:

127015891

CCRI:

104158589(NUDT5)

CSTI:

104551396(NUDT5)

EHS:	104516721(NUDT5)

CMAC:

104474571(NUDT5)

MUI:

104544361

FGA:	104080831(NUDT5)

GSTE:

104260292(NUDT5)

LDI:	104354551(NUDT5)

MNB:	103775961(NUDT5)

OHA:	104337624(NUDT5)

NNT:	104404482(NUDT5)

SHAB:

115605681(NUDT5) 115618563(NUDT18)

DPUB:

104300027(NUDT5)

PGUU:

104464780(NUDT5)

ACAR:

104525220(NUDT5)

CPEA:

104391916(NUDT5)

AVIT:

104274402(NUDT5)

CVF:	104284595(NUDT5)

CUCA:

104066285(NUDT5) 104068552(NUDT18)

TEO:	104371625(NUDT5)

BRHI:

104491297(NUDT5)

AAM:	106485164(NUDT18) 106485418(NUDT5)

AROW:

112978063(NUDT5)

NPD:	112942378(NUDT5)

TGT:	104569295(NUDT5)

DNE:	112994759(NUDT5) 112996719(NUDT18)

SCAM:

104149405(NUDT5)

ASN:	102373059(NUDT5) 102382475(NUDT18)

AMJ:	102562108(NUDT5) 102572685(NUDT18)

CPOO:

109315806(NUDT5) 109317430(NUDT18)

GGN:	109292219(NUDT5) 109295560(NUDT18)

PSS:	102447968(NUDT18) 102460805(NUDT5)

CMY:	102935770(NUDT18) 102941929(NUDT5)

CPIC:

101936689(NUDT18) 101938331(NUDT5)

TST:	117872985(NUDT18) 117874611(NUDT5)

CABI:

116835460(NUDT5) 116836901(NUDT18)

MRV:	120395231(NUDT5) 120399371(NUDT18)

ACS:	100558579(nudt18) 100567214(nudt5)

PVT:	110072074(NUDT18) 110081210(NUDT5)

SUND:

121930703(NUDT5) 121933516(NUDT18)

PBI:	103062314(NUDT18) 103064447(NUDT5)

PMUR:

107283241(NUDT18) 107297192(NUDT5)

CTIG:

120299390(NUDT18) 120314437(NUDT5)

TSR:	106542608(NUDT18) 106550928(NUDT5)

PGUT:

117668316(NUDT5) 117673310(NUDT18)

VKO:	123016775(NUDT18) 123020104(NUDT5)

PMUA:

114602703(NUDT18) 114605750(NUDT5)

ZVI:	118077463 118086871(NUDT18) 118091152(NUDT5)

GJA:	107111067(NUDT5) 107120358(NUDT18)

STOW:

125435403(NUDT5) 125441456(NUDT18)

XLA:	108712701(nudt18.S) 108713048(nudt5.S) 432263(nudt5.L)

XTR:	100488091(nudt18) 549367(nudt5)

NPR:	108784813(NUDT5) 108798459(NUDT18)

RTEM:

120931702(NUDT5) 120933133(NUDT18)

BBUF:

120983630(NUDT5) 120986324(NUDT18)

BGAR:

122925390(NUDT5) 122929390(NUDT18)

DRE:	415176(nudt5) 550541(nudt18)

SRX:	107726016 107743836 107756820 107756843

SANH:

107656337 107658859 107691561 107691590

SGH:	107580386 107584018(nudt5)

CCAR:

109053917 109053924 109066493(nudt5)

CAUA:

113058729(nudt5) 113070692 113107337

CGIB:

127956934 127963969 128018334

PPRM:

120474864(nudt18) 120476655(nudt5)

MAMB:

125245400(nudt5) 125279462(nudt18)

CIDE:

127511567 127517614

MASI:

127424546 127435377

IPU:	100528701(nudt5) 108265859(nudt18)

PHYP:

113532134(nudt5) 113546096(nudt18)

SMEO:

124399828(nudt18) 124400931(nudt5)

TFD:	113635093(nudt5) 113641980(nudt18)

AMEX:

103022158(nudt18) 103033374(nudt5)

EEE:	113584613(nudt5) 113590238(nudt18)

TRU:	101067864(nudt18) 115246641(nudt5)

TNG:	GSTEN00013252G001

LCO:	104930602(nudt5) 104936536(nudt18)

NCC:	104955336(nudt5)

CGOB:

115013962(nudt18) 115028144(nudt5)

ELY:	117249003(nudt5) 117252270(nudt18)

EFO:	125882832(nudt5) 125890724(nudt18)

PLEP:

121961712(nudt5)

SLUC:

116054528(nudt5) 116056871(nudt18)

ECRA:

117938651(nudt5) 117945145(nudt18)

ESP:	116672811(nudt5) 116689961(nudt18)

PFLV:

114550087(nudt5) 114555180(nudt18)

GAT:	120817693(nudt5) 120830753(nudt18)

PPUG:

119211301(nudt5) 119224755(nudt18)

MSAM:

119891586(nudt18) 119918013(nudt5)

CUD:	121505637(nudt5) 121506673 121509406(nudt18)

ALAT:

119019174(nudt18) 119032273(nudt5)

MZE:	101470680(nudt5) 101476216(nudt18)

ONL:	100691676(nudt5) 100701859(nudt18)

OAU:	116315334(nudt18) 116317027(nudt5)

OLA:	101160293(nudt18) 101161229(nudt5)

OML:	112138286(nudt5) 112142059(nudt18)

XMA:	102224507(nudt5) 102236783(nudt18)

XCO:	114145251(nudt18) 114161063(nudt5)

XHE:	116730068(nudt18) 116736820(nudt5)

PRET:

103459674(nudt5) 103470797(nudt18)

PFOR:

103129643(nudt18) 103151529(nudt5)

PLAI:

106937862(nudt18) 106939907(nudt5)

PMEI:

106908605(nudt18) 106910230(nudt5)

GAF:	122826518(nudt5) 122828576(nudt18)

CVG:	107096229(nudt5) 107103145(nudt18)

CTUL:

119791474(nudt18) 119794458(nudt5)

GMU:	124877850(nudt18) 124882691(nudt5)

NFU:	107382591(nudt5) 107386149(nudt18)

KMR:	108245546(nudt5) 108245838(nudt18)

ALIM:

106524598(nudt5)

NWH:	119413115(nudt18) 119428608(nudt5)

AOCE:

111579133(nudt5) 111587381(nudt18)

MCEP:

125000364(nudt5) 125012304(nudt18)

CSEM:

103383109(nudt5) 103398016(nudt18)

POV:	109632774(nudt5) 109645775(nudt18)

SSEN:

122766261(nudt5) 122769091(nudt18)

HHIP:

117756994(nudt5) 117768363(nudt18)

HSP:	118101933(nudt5) 118114724(nudt18)

LCF:	108874307 108875363 108891412

SDU:	111224766(nudt5) 111236953(nudt18)

SLAL:

111661228 111667281(nudt5)

XGL:	120799818(nudt5) 120805394(nudt18)

HCQ:	109525316(nudt18) 109528866(nudt5)

SSCV:

125992231 125993819

BPEC:

110161767(nudt5) 110162096(nudt18)

MALB:

109957397(nudt18) 109960917(nudt5)

BSPL:

114861381(nudt5) 114861461(nudt18)

SASA:

100196024(nudt5) 106587023(nudt18) 106609278(NUDT5)

STRU:

115167667(nudt18) 115180241 115198845

OTW:	112215017 112216934(nudt5) 112248922(nudt18)

OMY:	110490345 110500138 110526096(nudt18)

OGO:	123994568 124014450 124033990(nudt18)

ONE:	115111995(nudt18) 115119431 115133094

SALP:

111949778 111951434 111973665(nudt18)

SNH:	120032181 120044948(nudt18) 120050062

CCLU:

121543580 121559076 121584600(nudt18)

ELS:	105028521(nudt5) 105031473(nudt18)

SFM:	108929536(nudt18) 108931529(nudt5)

PKI:	111842369(nudt5) 111857588(nudt18)

AANG:

118206677(nudt18) 118231645(nudt5)

LOC:	102682917(nudt5) 102690044(nudt18)

PSPA:

121302419 121303219 121319847(nudt5)

ARUT:

117397913 117415728 117419430 117962513

PSEX:

120534052(nudt5) 120539294(nudt18)

LCM:	102346525(NUDT18) 102359306(NUDT5)

CMK:	103187912(nudt5)

RTP:	109922636(nudt18)

BFO:	118415934 118421740

BBEL:

109477274 109484668

SCLV:

120339050 120347350

SPU:	100893273 580253

APLC:

110983953 110987738

SKO:

100371378

DME:	Dmel_CG10898(CG10898)

DER:

6554063

DSE:

6606814

DSI:	Dsimw501_GD18763(Dsim_GD18763)

DYA:	Dyak_GE24179

DAN:

6501152

DSR:

110186991

DPO:

4802823

DPE:

6594594

DMN:

108155520

DWI:

6648085

DGR:

6568051

DMO:	Dmoj_GI10291

DAZ:

108613841

DNV:

108659652

DHE:

111604557

DVI:

6632292

CCAT:

101461781

BOD:

106624040

RZE:	108363247 108369023 108378534

MDE:

101888835

SCAC:

106081600

LCQ:

111690284

LSQ:

119601540

HIS:

119659155

AGA:	AgaP_AGAP002403

ACOZ:

120950951

AARA:

120902084

ASTE:

118506935

AAG:

5569095

AALB:

109405016 115253496

CQU:	CpipJ_CPIJ007497

CPII:

120413793

CNS:

116346687

BCOO:

119074648

AME:

413933

ACER:

107996869

ALAB:

122720482

BIM:

100742493

BBIF:

117215076

BVK:

117231842

BVAN:

117160260

BTER:

100648588

BPYO:

122577609

CCAL:

108625211

OBB:

114882897

MGEN:

117219638

NMEA:

116435018

CGIG:

122401381

SOC:

105199750

MPHA:

105840088

AEC:

105148604

ACEP:

105620493

PBAR:

105427990

VEM:

105568307

HST:

105182173

DQU:

106747881

CFO:

105256419

FEX:

115240476

LHU:

105670594

PGC:

109859396

OBO:

105284576

PCF:

106784337

PFUC:

122513465

VPS:

122636944

NVI:

100124005

CSOL:

105361283

TPRE:

106648337

MDL:

103570262

CGLO:

123262824 123266885

FAS:

105266436

DAM:

107036855

AGIF:

122860486

CINS:

118067486

CCIN:

107272277

TCA:

656819

DPA:

109546344

SOY:

115884432

ATD:

109600989

CSET:

123315828

AGB:

108910660

LDC:

111502829

NVL:

108569754

APLN:

108739077

PPYR:

116163100 116176451

OTU:

111417454

BMOR:

101740661

BMAN:

114248841

MSEX:

115451304

DPL:	KGM_203154

BANY:

112043067

NIQ:

126772226

PMAC:

106713793

PPOT:

106103048

PXU:

106121909

PRAP:

110998304

PBX:

123713703

PNAP:

125056327

ZCE:

119833854

CCRC:

123696854

HAW:

110370267

HZE:

124633882

TNL:

113498300

SLIU:

111357689

OFU:

114364144

PXY:

105381986

CFEL:

113370466 113370483 113370546

API:

100164703

DNX:

107165316

AGS:

114126579

RMD:	113551340 113552459

BTAB:

109037844 109039647

DCI:

103517714

CLEC:

106672324

HHAL:

106686903

NLU:

111051479

PHU:	Phum_PHUM430950

FOC:	113204597 113206125

TPAL:

117645005 117652329

ZNE:	110831927 110838996

CSEC:

111861833 111866312

SGRE:

126297490 126298077

FCD:	110850781 110854416

DPX:	DAPPUDRAFT_202142

DMK:

116924793

DPZ:

124336107

PVM:	113803116 113820552

PJA:

122259222

PCHN:

125046930

PMOO:

119588568 119591264

HAME:

121857297 121862444

PCLA:

123767535

PTRU:

123509668

HAZT:

108672263

LSM:

121122805

PPOI:

119101083

ISC:	IscW_ISCW015557 IscW_ISCW021976

DSV:	119460937 119465892

RSAN:

119371980 119396620

RMP:	119163799 119174785

VDE:

111245848

VJA:

111258620

TUT:	107360643 107369877

DPTE:

113789553 113791511

DFR:	124496905 124499901

CSCU:

111621324 111637376

PTEP:

107436389 107454369

SDM:	118186858 118202731

CEL:	CELE_T26E3.2(ndx-1)

CBR:	CBG_08712(Cbr-ndx-1)

LOA:	LOAG_03218 LOAG_11777

NAI:	NECAME_00964

HRO:	HELRODRAFT_159814

LGI:	LOTGIDRAFT_204741 LOTGIDRAFT_232724

PCAN:

112566284 112571706

BGT:

106050625

GAE:	121372150 121390067

HRF:	124111850 124136284

HRJ:	124274859 124281969

CRG:	105337872 117683170

MYI:

110448861

PMAX:

117326755 117331692

MCAF:

127720351

MMER:

123528667 123552079

DPOL:

127852132 127881839

OBI:	106881854 106882270

OSN:	115210667 115222998

LAK:	106159149 106165124 106166567

OVI:	T265_04883

NVE:	5499025 5506782

EPA:

110246095

ATEN:

116299913

ADF:

107345269

PDAM:

113686343

SPIS:

111328440

TAD:	TRIADDRAFT_54258

AQU:	100631490 100632790

OLU:	OSTLU_38092

OTA:	OT_ostta10g00760

PAN:	PODANSg4001

ACAN:

ACA1_131000 ACA1_131530 ACA1_177470

FCY:	FRACYDRAFT_162205

GTT:	GUITHDRAFT_166567

YRE:	HEC60_24675

CATT:

OLW01_12765

MARQ:

MARGE09_P2171

MKE:	OOT55_15035

SPOI:

IMCC21906_02442

SNAN:

I6N98_07445

STAW:

NCG89_16155

ZAL:	AZF00_06300

OSG:	BST96_12135

MCA:

MCA0333

METU:

GNH96_01710

MMAI:

sS8_5326

MMOB:

F6R98_07380

TTP:	E6P07_08605

THIP:

N838_18320

WOC:	BA177_00665

GAI:	IMCC3135_31060(nudF_2)

HCH:

HCH_04775

BACZ:

KFF03_05905

GSN:	YC6258_01198

SLIM:

SCL_0864

CDIZ:

CEDIAZO_01771(nudF_2)

JEU:	BJP62_11335

ARA:

Arad_1531

RTR:	RTCIAT899_CH05605

RJG:	CCGE525_06840

RHR:	CKA34_08750 CKA34_33565

RLS:	HB780_31390

MRD:	Mrad2831_1222

MOR:

MOC_1449

MPHY:

MCBMB27_00826

MEE:	DA075_28830

METX:

A3862_24550

METS:

DK389_16390

MTEA:

DK419_28115

MIND:

mvi_39120

MOC:	BB934_32835

MHEY:

H2LOC_015945

MTW:	CQW49_11940

CCS:	CCNA_03765

CAK:

Caul_3753

CSE:	Cseg_1048 Cseg_4141

CHQ:	AQ619_04235 AQ619_17455

CFH:	C1707_01740

CAUF:

CSW63_22615

PZU:

PHZ_c2226

HBA:

Hbal_0637

GDI:

GDI1308

GDJ:

Gdia_2018

GXY:

GLX_19050

GXL:

H845_3097

KNA:	B0W47_09535

KEU:	S101446_02377(nudF)

KSC:	CD178_01054(nudF_1)

AOT:	AcetOri_orf03024

KBA:	A0U89_00095

ROS:	CTJ15_11325

NEH:	E3E11_02540

BOB:	GN304_01395

BOMB:

GT348_06895

LCK:	HN018_01340

ALI:	AZOLI_p60014

AZM:	DM194_26765

SROE:

JL101_005850

RCE:

RC1_1156

MAG:

amb1066

NDT:	L1999_27250

AAC:

Aaci_2209

AAD:

TC41_2335

MTU:

Rv1700

MTV:

RVBD_1700

MTC:

MT1739

MRA:

MRA_1709

MTF:	TBFG_11715

MTB:	TBMG_02296

MTK:	TBSG_02308

MTZ:	TBXG_002278

MTG:	MRGA327_10555

MTE:	CCDC5079_1575

MTUR:

CFBS_1791

MTL:	CCDC5180_1560

MTO:	MTCTRI2_1729

MTD:

UDA_1700

MTN:	ERDMAN_1867

MTJ:	J112_09070

MTUB:

MT7199_1722

MTUE:

J114_09080

MTX:	M943_08850

MTUL:

TBHG_01658

MTUT:

HKBT1_1790

MTUU:

HKBT2_1798

MTQ:	HKBS1_1794

MBO:	BQ2027_MB1726

MBB:

BCG_1738

MBT:

JTY_1713

MBM:	BCGMEX_1710

MBK:	K60_017850

MBX:

BCGT_1514

MAF:

MAF_17180

MMIC:

RN08_1883

MCE:	MCAN_17091

MCQ:	BN44_20266

MCV:	BN43_30820

MCX:	BN42_21629

MCZ:	BN45_40175

MPA:	MAP_1407 MAP_2477c

MAO:	MAP4_1346 MAP4_2438

MAVI:

RC58_06660 RC58_12125

MAVU:

RE97_06650 RE97_12140

MAV:	MAV_1446 MAV_3071

MIT:	OCO_15440 OCO_29130

MIA:	OCU_15880 OCU_29050

MID:	MIP_02151 MIP_04286

MYO:	OEM_13530 OEM_28360

MCHI:

AN480_07715 AN480_15225

MIR:	OCQ_13350 OCQ_29800

MMAL:

CKJ54_06515 CKJ54_13325

MLP:	MLM_1378 MLM_2444

MMAN:

MMAN_09390 MMAN_26190

MSA:	Mycsm_03116 Mycsm_04897

MUL:

MUL_1689

MMI:	MMAR_2505 MMAR_4125

MMAE:

MMARE11_24330 MMARE11_39350

MLI:	MULP_03108 MULP_04290

MPSE:

MPSD_17510 MPSD_25590

MSHO:

MSHO_16800 MSHO_37810

MMC:	Mmcs_2943 Mmcs_4021

MKM:	Mkms_2987 Mkms_4096

MJL:	Mjls_2958 Mjls_4251

MMM:	W7S_06525 W7S_14485

MKN:	MKAN_06470 MKAN_28380

MYV:	G155_17030

MYE:	AB431_17735 AB431_23195

MHAD:

B586_08025 B586_12315

MDX:	BTO20_14690

MSHG:

MSG_02372 MSG_03698

MFJ:	MFLOJ_08880 MFLOJ_49710

MSTO:

MSTO_10020 MSTO_53870

MSIM:

MSIM_39520 MSIM_54020

MSAK:

MSAS_04880 MSAS_19900

MKU:	I2456_12425 I2456_19510

MLW:	MJO58_12565

MGRO:

FZ046_19455 FZ046_25990

MXE:	MYXE_26660

MNV:	MNVI_39530

MPAG:

C0J29_14265 C0J29_22680

MNM:	MNVM_41960

MGOR:

H0P51_13475 H0P51_20740

MCOO:

MCOO_07080 MCOO_13950

MBAI:

MB901379_02331(nudF_1) MB901379_03601(nudF_2)

MSEO:

MSEO_11840 MSEO_24860

MHEK:

JMUB5695_02621

MGAU:

MGALJ_18660 MGALJ_28770

MLJ:	MLAC_09430 MLAC_15920

MBRD:

MBRA_40530

MSHJ:

MSHI_05120 MSHI_14980

MMAM:

K3U93_11570 K3U93_17675

MSPG:

F6B93_10485 F6B93_16510

MOT:	LTS72_04740 LTS72_11725

MLM:	MLPF_1904(nudF)

MPAA:

MKK62_11755

MMEH:

M5I08_10150

MSM:	MSMEG_3745

MSG:	MSMEI_3655

MSB:	LJ00_18605

MSN:	LI99_18610

MSH:	LI98_18615

MVA:	Mvan_3282 Mvan_4523

MGI:	Mflv_2174 Mflv_3501

MSP:	Mspyr1_16060 Mspyr1_28400

MCB:	Mycch_2641 Mycch_3927

MNE:	D174_17085

MYN:	MyAD_16740

MFT:	XA26_34770

MPHL:

MPHLCCUG_02278(nudF_1) MPHLCCUG_04063(nudF_2)

MVQ:	MYVA_2820 MYVA_4299

MLL:	B1R94_06890

MRH:	MycrhN_3665 MycrhN_4691

MTHN:

4412656_02138(nudF_1)

MHAS:

MHAS_01741(act) MHAS_02859(nudF)

MDU:	MDUV_02000 MDUV_14360

MCHT:

MCHIJ_26560 MCHIJ_36230

MDR:	MDOR_21480 MDOR_28310

MAUU:

NCTC10437_03129(nudF_1) NCTC10437_04253(nudF_2)

MMAG:

MMAD_32490 MMAD_41760

MMOR:

MMOR_20670 MMOR_31870

MFX:	MFAL_10320

MAIC:

MAIC_31100 MAIC_41900

MIJ:	MINS_29110

MALV:

MALV_05080

MTY:	MTOK_03370 MTOK_50970

MPSC:

MPSYJ_23400 MPSYJ_37600

MARZ:

MARA_11280 MARA_55200

MGAD:

MGAD_06130 MGAD_53650

MHEV:

MHEL_08550 MHEL_54960

MSAR:

MSAR_27900 MSAR_37940

MANY:

MANY_16220 MANY_25460

MAUB:

MAUB_09230 MAUB_44500

MPOF:

MPOR_32270 MPOR_45860

MPHU:

MPHO_04140 MPHO_24810

MMUC:

C1S78_005960 C1S78_016375

MMAT:

MMAGJ_69280

MBOK:

MBOE_39530

MFG:	K6L26_14900

MSEI:

MSEDJ_40200

MFLV:

NCTC10271_02645(nudF_2)

MCEE:

MCEL_09130

MBRM:

L2Z93_001925

MMON:

EWR22_15500

MGO:	AFA91_14955 AFA91_21240

MHOL:

K3U96_13235

MSEN:

K3U95_14435

MPAE:

K0O64_16925

MRF:	MJO55_13450 MJO55_20395

MDF:	K0O62_16935

MCRO:

MI149_17800

MKR:	MKOR_01720

MPAK:

MIU77_05200

MAB:

MAB_2365

MMV:	MYCMA_1276

MABB:

MASS_2289

MABL:

MMASJCM_2314

MCHE:

BB28_11860

MIZ:	BAB75_12610

MSTE:

MSTE_02302

MSAO:

MYCSP_11115

MSAL:

DSM43276_02085(nudF)

MJD:	JDM601_1856

MTER:

4434518_01810(nudF)

MMIN:

MMIN_34830

MHIB:

MHIB_13080

MHER:

K3U94_10510

MVM:	MJO54_10650

ASD:

AS9A_1530

CGL:	Cgl1418(Cgl1418)

CGB:

cg1607

CGU:

WA5_1363

CGT:

cgR_1479

CGS:	C624_07885

CGG:	C629_07895

CGM:

cgp_1607

CGJ:

AR0_07625

CGQ:	CGLAR1_07490

CGX:	SB89_07320

CEF:

CE1552

CDI:

DIP1185

CDP:	CD241_1116

CDH:	CDB402_1095

CDT:	CDHC01_1114

CDE:	CDHC02_1095

CDR:	CDHC03_1089

CDA:	CDHC04_1099

CDZ:	CD31A_1197

CDB:	CDBH8_1167

CDS:	CDC7B_1181

CDD:	CDCE8392_1086

CDW:	CDPW8_1164

CDV:	CDVA01_1056

CDIP:

ERS451417_01182(nudF)

CJK:

jk0872

CAR:	cauri_1328

CKP:	ckrop_0856

CPU:	CPFRC_04880

CPL:	Cp3995_0986(nudF)

CPG:	CP316_05045

CPP:	CpP54B96_0981(nudF)

CPK:	CP1002_08265

CPQ:	CPC231_04880

CPX:	CPI19_06640

CPZ:	CpPAT10_0964(nudF)

COR:	Cp267_1009(nudF)

COP:	CP31_05275

COD:	Cp106_0953(nudF)

COS:	Cp4202_0958(nudF)

COI:	CPCIP5297_05065

COE:	CP258_05060

COU:	CP162_06230

CPSE:

CPTA_01534

CPSU:

CPTB_02230

CPSF:

CPTC_01525

CRD:

CRES_0970

CUL:	CULC22_01039

CUC:	CULC809_01024

CUE:	CULC0102_1144

CUN:	Cul210932_1076(nudF)

CUS:	CulFRC11_1047(nudF)

CUQ:	Cul210931_1030(nudF)

CUZ:	Cul05146_1099(nudF)

CUJ:	CUL131002_1060(nudF)

CVA:

CVAR_1275

CHN:	A605_06935

CCN:	H924_06540

CTER:

A606_05185

CMD:	B841_06490

CAZ:	CARG_04490

CFN:	CFAL_04990

CCG:	CCASEI_07690

CVT:	B843_06695

CGY:	CGLY_09175

CAX:	CATYP_05620

CII:	CIMIT_06050

CUV:	CUREI_05850

COA:

DR71_123

CDO:	CDOO_07020

CHM:	B842_06310

CSX:	CSING_07290

CMQ:	B840_05905

CKU:	UL82_04880

CCJ:	UL81_05710

CMV:	CMUST_07710

CEI:	CEPID_05965

CTED:

CTEST_06245

CUT:	CUTER_05200

CLW:	CLAC_06815

CDX:	CDES_06885

CSP:

WM42_0022

CSTA:

CSTAT_06990

CCJZ:

ccrud_06800

CFK:	CFRA_06165

CPHO:

CPHO_06335

CFC:	CFLV_06070

CGV:	CGLAU_06140(nudF)

CSTR:

CBE89_06930

CAQU:

CAQU_06035

CSPH:

CSPHI_07050

CAMG:

CAMM_07230

CMIN:

NCTC10288_01190(nudF)

CPEG:

CPELA_05935(nudF)

CXE:	FOB82_12880

CEE:	CENDO_05535(nudF)

CSAN:

E3227_09585

CGK:	CGERO_05255(nudF)

CRF:	FRC0190_01161

CRL:	NCTC7448_01863(nudF)

CCHO:

CCHOA_05435(nudF)

CPRE:

Csp1_15070(act)

CPSO:

CPPEL_06165(nudF)

CSUR:

N24_1512(nudF)

CCYS:

SAMEA4530656_1170(nudF)

CMAT:

HBA49_12645

CYZ:	C3B44_05955

CKF:	I6I12_07030

CANS:

GP473_04010

CLIA:

C3E79_05310

CPRP:

I6I69_10760

CAMC:

I6I65_03015

CGLU:

I6J20_04040

CUO:	CUROG_04450(nudF)

CLIZ:

G7Y31_05545

CSIL:

CBE74_05825

CTUB:

I6I74_10775

CLUJ:

IAU68_05665

CQN:	G7Y29_05155

CKW:	CKALI_05285(nudF)

CCOE:

CETAM_06315(nudF)

COK:	COCCU_06800(nudF)

CZO:	IAU67_03935

CCYC:

SCMU_16910

CORY:

FQV43_04835

CMF:	GWO64_006450

CWK:	IA203_06250

CUW:	LH390_05500

CPOY:

GP475_05610

CACC:

CACC_06105(nudF)

CFY:	I6L56_03255

CPSL:

KBP54_05600

CHIN:

J5O04_08590

CJH:	CJEDD_06275(nudF)

CPSP:

L9H27_05075

BFV:	C628_07820

NFA:

NFA_20060

NFR:	ERS450000_02104(nudF)

NCY:	NOCYR_2198

NBR:	O3I_013775

NNO:	NONO_c25980(nudF) NONO_c75410

NSL:	BOX37_07945 BOX37_10320

NSR:	NS506_05665

NTP:	CRH09_13970 CRH09_38940

NOZ:	DMB37_33905

NOD:	FOH10_08140 FOH10_09860 FOH10_12055

NAH:	F5544_14570 F5544_17215

NAD:	NCTC11293_03123(nudF)

NWL:	NWFMUON74_45830 NWFMUON74_70510

NIE:	KV110_13180

NTC:	KHQ06_19150

NHU:	H0264_18135

NYA:	LTV02_17255

NGP:	LTT66_01145

RHA:	RHA1_ro00930

RER:	RER_32610(nudF)

REY:

O5Y_15020

REB:	XU06_15250

RQI:	C1M55_16270

ROP:	ROP_06630(nudF)

ROA:	Pd630_LPD05015

RPY:	Y013_04620

RBY:	CEJ39_15415

RHB:

NY08_851

RAV:	AAT18_14240

RFA:	A3L23_04097(nudF)

RHS:	A3Q41_04146(nudF)

RHW:	BFN03_08740

RRZ:	CS378_03915

RHU:	A3Q40_01838(act)

RHQ:	IM25_18785

RHOD:

AOT96_26450

RRT:	4535765_02753(nudF)

RCR:	NCTC10994_00290(nudF)

RTM:	G4H71_22260

RKO:	JWS14_04855

RGO:	KYT97_05000

ROZ:	CBI38_13205

RPSK:

JWS13_41575

RGOR:

NMQ04_11630

REQ:

REQ_24660

GBR:

Gbro_2822

GPO:	GPOL_c25890(nudF)

GOR:

KTR9_2698

GOQ:	ACH46_11725

GTA:	BCM27_14310

GOC:	CXX93_11600

GIT:	C6V83_12020

GRU:	GCWB2_10390(nudF)

GOM:	D7316_01308(act)

GAV:	C5O27_17225

GOD:	GKZ92_10095

GAM:	GII34_13390

GPD:	GII33_12580

GJI:	H1R19_13545

GOI:	LK459_20210

GHN:	MVF96_14035

GAMI:

IHQ52_13330

GMG:	NWF22_23665

SPIN:

KV203_11035

TPR:

Tpau_2376

TSM:	ASU32_12840

TPUL:

TPB0596_22100

SRT:

Srot_2545

DTM:	BJL86_1499

DIT:	C3V38_13010

DIZ:	CT688_07355

DPC:	A6048_07200

DLU:	A6035_07180

DKN:	NHB83_06930

CBQ:	AL705_08220

TOY:	FO059_08185

SCO:	SCO1775(SCI51.15c)

SALB:

XNR_5049

SMA:	SAVERM_6505(nudF)

SGR:

SGR_5722

SGB:

WQO_06700

SCB:	SCAB_37771 SCAB_71811

SSX:	SACTE_1203

SVL:	Strvi_6858

SHY:

SHJG_3222

SHO:	SHJGH_2986

SRC:	M271_37460

SMAL:

SMALA_1725

SSOI:

I1A49_11770

SFA:

Sfla_5045

SBH:	SBI_08236(nudF)

SVE:

SVEN_1409

SDV:	BN159_6770

SALS:

SLNWT_5190 SLNWT_6104

STRP:

F750_1629

SFI:	SFUL_1328 SFUL_3747

SCI:	B446_09185

SLV:	SLIV_28865

SGU:	SGLAU_07825

SVT:	SVTN_08500 SVTN_39585

STRE:

GZL_06746

SCW:	TU94_07460

SLD:

T261_6395

SLC:	SL103_10395 SL103_34165

SXI:	SXIM_07650

STRM:

M444_00425 M444_09215

STRC:

AA958_04950

SAMB:

SAM23877_1833

SPRI:

SPRI_5749

SCZ:	ABE83_29140

SCX:	AS200_34440

SRW:	TUE45_02244(nudF_2)

STRF:

ASR50_08555

SLE:	sle_53590(sle_53590)

SRN:	A4G23_01002(nudF_1) A4G23_03481(nudF_2)

SPAV:

Spa2297_07000

STRT:

A8713_06440

SCLF:

BB341_23065

SGS:	AVL59_35610

STSI:

A4E84_08930

SKY:	D0C37_27265

SALW:

CP975_07360

SGM:	GCM10017557_64870

SCAD:

DN051_29730

SPHW:

NFX46_29465

SLS:	SLINC_2035

SNR:	SNOUR_02235 SNOUR_31435

SALU:

DC74_2264

SALL:

SAZ_12005

SPLU:

LK06_005705

STRD:

NI25_16100 NI25_27885 NI25_30345

SNW:	BBN63_27660

SAUO:

BV401_12080

SSIA:

A7J05_18370 A7J05_28100

SVU:	B1H20_05880 B1H20_17670

SPUN:

BFF78_17710 BFF78_32555 BFF78_36110

SGV:	B1H19_10880

SLAU:

SLA_1315

SALF:

SMD44_01898(nudF)

SALJ:

SMD11_5233(nudF)

SLX:	SLAV_28570(nudF1)

STRO:

STRMOE7_09710

SFK:

KY5_1675c

SNZ:	DC008_07040

SGE:	DWG14_06647(nudF)

SRJ:

SRO_5696

SLK:	SLUN_08505 SLUN_16885

SDX:	C4B68_07260 C4B68_31615

SGD:	ELQ87_30740

SQZ:	FQU76_05560 FQU76_23340

SCYA:

EJ357_10130

SAST:

CD934_26815

SNQ:	CP978_08395 CP978_19685

STIR:

DDW44_07270

SKA:	CP970_34300

SGZ:	C0216_22155

SVN:	CP980_25925

SNK:	CP967_24890 CP967_27460

SHAW:

CEB94_09370

SRK:	FGW37_07415 FGW37_17150

SFIC:

EIZ62_26240

SGAL:

CP966_07445

SSPO:

DDQ41_05265

SVR:	CP971_08530

SPAD:

DVK44_04900

SFY:	GFH48_31350

SAQU:

EJC51_11885

SGF:	HEP81_06002

SCAV:

CVT27_05525 CVT27_16870

SSEO:

D0Z67_05755

SBY:	H7H31_28435

SRIM:

CP984_02915 CP984_32185

SSUB:

CP968_25730

SPHV:

F9278_08710

SCIN:

CP977_07915 CP977_13675

SFUG:

CNQ36_07545

SPAC:

B1H29_28665

STSU:

B7R87_05565 B7R87_23090

SCHA:

CP983_33940

SGX:	H4W23_08945

SCOE:

CP976_10045

SBAT:

G4Z16_27685

SSPB:

CP982_10480

SNF:	JYK04_02439(nudF)

SPLA:

CP981_08785

SBRO:

GQF42_11635

STUI:

GCM10017668_13670

SATA:

C5746_09675

SCHF:

IPT68_08045

SHUN:

DWB77_05954(nudF_2)

SHAR:

HUT13_04390

SCYG:

S1361_09775(nudF2)

SFEU:

IM697_13495

SLIA:

HA039_27090

SDW:	K7C20_08300

SVD:	CP969_09830

SCAL:

I6J39_06050

SAUH:

SU9_006760

SFB:	CP974_05195

SMOB:

J7W19_02265 J7W19_06715

SPRA:

CP972_07900

SPEU:

CGZ69_07480

SROI:

IAG44_31555

SXN:	IAG42_27995

SGJ:	IAG43_06380

SHK:	J2N69_07180

SANU:

K7396_27985

SDD:	D9753_27910

SACT:

DMT42_08010

SMAO:

CAG99_23885

SGOB:

test1122_01970

SINE:

KI385_11375

SLF:	JEQ17_36180

SDEC:

L3078_10270

SAOV:

G3H79_29615

SDUR:

M4V62_32685

SYAN:

NRK68_07930

SRUG:

F0345_04915

SAKB:

K1J60_35295

STAA:

LDH80_30465

SNIG:

HEK616_17260

SVIO:

HWN34_25490

SCT:	SCAT_0970(nudF)

SCY:	SCATT_09710

KSK:	KSE_04980 KSE_57440(nudF1)

KAB:	B7C62_05640

KAU:	B6264_03590

KIT:	CFP65_3873 CFP65_5671

KIS:	HUT16_01095 HUT16_26845

STRI:

C7M71_024490

YIA:	LO772_25760

STRH:

GXP74_30235

ABRY:

NYE86_10655

TWH:

TWT_098

TWS:

TW109

LXL:	KDY119_01584(nudF)

PSIC:

J4E96_07145

LXX:	Lxx05660(mutT)

LXY:	O159_21340

LEIF:

HF024_05780

LSE:	F1C12_07435

CMI:

CMM_1982

CMS:

CMS1250

CMC:

CMN_01943

CMH:	VO01_09145

CCAP:

AES38_00900 AES38_09635

CZH:	H9X71_09940

CPHA:

FGI33_03235

CCAF:

FGD68_12335

MTS:	MTES_0314 MTES_2180

MIM:	AKG07_02585 AKG07_06430

MIO:	AOA12_14095

MIX:	AB663_002208 AB663_003025

MIP:	AXH82_00245 AXH82_13555

MCW:	A8L33_08760

MPAL:

BO218_05960 BO218_14095

MIH:	BJP65_03530 BJP65_11670

MICR:

BMW26_07155 BMW26_10940

MAUR:

BOH66_11495

MHOS:

CXR34_03470 CXR34_12205

MFOL:

DXT68_07030 DXT68_10890

MOO:	BWL13_00991(act)

MLV:	CVS47_01121(act)

MWA:	E4K62_06435

MPRT:

ET475_13225

MSED:

E3O41_09165

MOY:	CVS54_01387(act_1) CVS54_02137(act_2)

MSF:	IT882_04970 IT882_05245

MCAW:

F6J84_09885 F6J84_10185

MLZ:	F6J85_06150

MCHN:

HCR76_09445

MRN:	K8F61_01910

MICS:

C1N74_05110 C1N74_13075

MBIN:

LXM64_10525

MLIQ:

NMQ05_06790

MTEC:

OAU46_09730

MPAO:

IZR02_10620

RLA:	Rhola_00008950

RPLA:

A4Z71_04325

RTX:	TI83_04685

RTC:	APU90_01790

RTN:	A6122_1040

RRY:	C1O28_04420 C1O28_12245

RIA:	C7V51_01940

RFS:	C1I64_09540 C1I64_14860

RTE:	GSU10_01350 GSU10_05855

CUB:	BJK06_10825

CUG:	C1N91_13990

CQF:	GBG65_04045

MVD:	AWU67_08600

FRP:	AX769_11095

AGY:	ATC03_05795 ATC03_12375

AGM:	DCE93_05985 DCE93_11165

AGF:	ET445_07560 ET445_14010

AARC:

G127AT_01645

AMAU:

DSM26151_12410

ASOI:

MTP13_15620

CART:

PA27867_1198

CRY:	B7495_05945

CPHY:

B5808_07000

AMIN:

AUMI_17010

AUM:	AURMO_00987

AUW:	AURUGA1_00679(nudF)

PSAI:

C3B54_111178

MALK:

MalAC0309_1164

MYL:	C3E77_05480

MSPO:

KXZ72_06010

SALC:

C2138_04800

SALA:

ESZ53_01230

SALD:

FVA74_04885

HUM:	DVJ78_13890

HUW:	FPZ11_00945

GRY:	D7I44_07325 D7I44_14255

LYD:	D7I47_14450

LYK:	FLP23_07760

LEU:	Leucomu_02200

LTR:	EVS81_06420

LEB:	G7066_04280

LDN:	H9L06_10480

LVI:	G7068_13445

LLUT:

K1X41_05725

LARI:

KI794_02930

AGG:	C1N71_09200

MANT:

BHD05_12845

HEA:	HL652_05135

HEH:	L3i23_10420

FRN:	F1C15_03210

GLN:	F1C58_06365

CHRE:

IE160_07525

AGX:	AGREI_1359

SUBT:

KPL76_09975

SUBA:

LQ955_08125

PSEV:

USB125703_02082(act)

GSD:	M3M28_08080

GMN:	GMOLON4_383(mutT)

HOM:	OF852_04510

ART:

Arth_1520

ARR:	ARUE_c15660

ARM:

ART_0013

ARL:	AFL94_05510

ARE:	AL755_07840

AAQ:	AOC05_04345

ARW:	MB46_04275

ARY:	ATC04_12375

ARZ:	AUT26_07265

ARU:	ASPU41_12905

ARQ:	BWQ92_02410

ARN:	CGK93_08555

ARX:	ARZXY2_2330(nudF)

ACRY:

AC20117_17065

ARTH:

C3B78_07220

ARTP:

E5206_15835

AAGI:

NCTC2676_1_01039(nudF)

AJG:	KKR91_06210

ASUN:

KG104_06550

ASUF:

MNQ99_12215

ARTY:

AHiyo4_18210

APOA:

J0916_04255

ARI:	UM93_02290

AAU:

AAur_1656

PUE:	FV140_08065

PNV:	JMY29_07865

ACH:	Achl_1519 Achl_3962

APN:	Asphe3_15010

PSUL:

AU252_02780

PSNI:

NIBR502771_18075

PSEY:

GU243_01990

AAI:	AARI_11640

GAR:	AOZ07_06125

GCR:	GcLGCM259_0949(nudF)

GLU:	F0M17_05785

GPR:	JQN66_05960

GMI:	NMP99_06175

GMY:

XH9_02900

RSA:	RSal33209_0816

KRH:	KRH_15350(nudF)

KPL:	KPaMU14_07745

KFV:	AS188_08745

KII:	KocCE7_08180

KRS:	EQG70_11475

KOD:	HBK84_08175

KVR:	CIB50_0001566(act)

MLU:	Mlut_14200

MICK:

B1A86_00007080

MYU:	M8233_06815

RMU:	RMDY18_14020

RDN:	HMPREF0733_11623

RAJ:	RA11412_1333

RTER:

IDM49_07900

RAMA:

IDM48_07610

RKR:	I6G21_07600

SATK:

SA2016_1752

NAE:	BHE16_03670

AUL:	DCC27_004815

PAEY:

KUF55_05995

BCV:	Bcav_2192 Bcav_2348

BFA:	Bfae_13740

BRX:	BH708_01285

BRV:	CFK39_14765

BGG:	CFK41_10075

BRZ:	CFK38_12720

BSAU:

DWV08_04220

BRR:	C1N80_12075

BKI:	M4486_06850

BRHA:

NLU66_13150

BHH:	Bra3105_03555

BHQ:	BRM3_13245

DVA:	DAD186_09280

DJJ:	COP05_06275

JDE:

Jden_1133

KSE:	Ksed_12410 Ksed_14570

DNI:	HX89_08515 HX89_13475

DAY:	FV141_07720

DERM:

H7F30_09695

LMOI:

VV02_13825

YIM:	J5M86_06410 J5M86_13615

ALX:	LVQ62_13730

XCE:

Xcel_1348

XYL:	ET495_02940 ET495_03760

XYA:	ET471_12255 ET471_13355

IVA:	Isova_1361

IDO:	I598_0901(nudF)

CET:	B8281_14125

CCEU:

CBR64_17275

CPRT:

FIC82_013005

SKE:	Sked_22070

SANW:

G7063_06855

CFL:

Cfla_1665

CFI:

Celf_1683

CGA:	Celgi_1931

CEZ:	CBP52_03700

CELZ:

E5225_09925

CEJ:	GC089_10270 GC089_17145

CELH:

GXP71_05220

CIRA:

LFM56_09995

CPAL:

F1D97_10525

CELC:

K5O09_11035

CDON:

KKR89_08120

CWAN:

KG103_08375

CFEN:

KG102_07435

OEK:	FFI11_012090

PSEI:

GCE65_05905

ICA:	Intca_1575 Intca_3100

ARS:	ADJ73_11035

JTE:	ASJ30_08875

JLI:	EXU32_05475

JME:	EEW87_006335

JAY:	H7A72_09030

TEH:	GKE56_03335

PHW:	G7075_03715 G7075_07755

PEI:	H9L10_05050

SERJ:

SGUI_0172

SERW:

FY030_08860

ORN:	DV701_01865

ORZ:	FNH13_11840

BLY:	A2T55_10895

BLIN:

BLSMQ_2393

BRI:	FDF13_13000

BLUT:

EW640_01545

BCAU:

I6G59_14470

DCO:	SAMEA4475696_1215(nudF)

AUS:	IPK37_19665

GEZ:	FE251_10510

GYU:	FE374_06960

HALT:

IM660_08365

RHAL:

LQF10_11230

RSUA:

LQF12_06915

DEM:	LGT36_005765

PAC:

PPA1389

PAK:	HMPREF0675_4438

PAV:	TIA2EST22_06935

PAX:	TIA2EST36_06910

PAZ:	TIA2EST2_06840

PAW:	PAZ_c14610

PAD:	TIIST44_07590

PCN:	TIB1ST10_07150

PACC:

PAC1_07295

PACH:

PAGK_0792

PACN:

TIA1EST1_06925

CACN:

RN83_07380

PRA:	PALO_04125

PRL:	BCB70_03570

CGRN:

4412665_01510(nudF)

PFR:	PFREUD_13640(nudF)

PFRE:

RM25_1300

PACD:

EGX94_01870

PAUS:

NCTC13651_02291(nudF)

PPC:	HMPREF9154_2009

ARUB:

J5A65_05800

PBO:	PACID_20830

ACIJ:

JS278_01396(nudF)

AJI:	C0Z10_05105

MPH:

MLP_17470

MIK:	FOE78_16415

MICG:

GJV80_10390

TFL:	RPIT_08075

TFA:	BW733_14970

TES:	BW730_03135

TEZ:	BKM78_02425

TDF:	H9L22_07120

TLA:	TLA_TLA_00492(act)

TEJ:	KDB89_05415

RAIN:

Rai3103_15855

PRV:	G7070_17110

BRT:	J4N02_07095

NCA:	Noca_2486 Noca_3458

NDK:	I601_3080(nudF)

NOY:	EXE57_02625

NOI:	FCL41_07290

NOO:	FE634_11660

NSN:	EXE58_17290

NBE:	Back2_03410

NANO:

G5V58_12105

NMES:

H9L09_19590

NARO:

CFH99_11935

NPI:	G7071_14385

NAQU:

ENKNEFLB_02056(nudF)

NRO:	K8W59_07990

NOQ:	LN652_03250

NCQ:	K6T13_08030

NPC:	KUV85_02360 KUV85_05505

NPS:	KRR39_10900

PSIM:

KR76_12585

AER:	AERYTH_12325

AEZ:	C3E78_09895

AEB:	C6I20_08735

AEF:	GEV26_09815

MGG:	MPLG2_1750

MUZ:	H4N58_09430

KFL:	Kfla_1627 Kfla_5412

KQI:	F1D05_08125 F1D05_11110

TFU:

Tfu_1200

THAO:

NI17_003465

TALX:

FOF52_02850

NDA:

Ndas_0970

NAL:

B005_3896

NGV:	CDO52_12615 CDO52_17580

NEX:	NE857_12005

NEC:	KGD82_18020

STRR:

EKD16_11085(nudF)

SNAH:

OUQ99_22230

SAIU:

J4H86_04510

TCU:	Tcur_2006 Tcur_2835

ACTW:

F7P10_21900 F7P10_37565

AGRA:

AGRA3207_006991

SRO:	Sros_0703 Sros_2991

NOA:	BKM31_27505 BKM31_52150

NOW:	GBF35_18920

NCX:	Nocox_15985(nudF1)

NGN:	LCN96_19055

TBI:	Tbis_0341 Tbis_1488

FRA:	Francci3_3156

FRE:	Franean1_1755 Franean1_4797

FRI:	FraEuI1c_1732 FraEuI1c_5849 FraEuI1c_5850

FAL:	FRAAL5178(nudF) FRAAL6419

FSY:	FsymDg_3248

ACE:

Acel_1242

NML:	Namu_4016 Namu_4063

NAK:	EH165_04870

GOB:

Gobs_3000

BSD:	BLASA_2492

BLAP:

MVA48_04550

MMAR:

MODMU_0123 MODMU_3171(nudF)

KRA:

Krad_3140

SEN:	SACE_5243(nudF) SACE_6265

SACG:

FDZ84_01275 FDZ84_06285

SVI:	Svir_25410 Svir_29440

SACC:

EYD13_14145(nudF1) EYD13_16270(nudF2)

AMD:

AMED_6013

AMN:

RAM_30835

AMM:

AMES_5929

AMZ:

B737_5929

AOI:	AORI_4492(nudF) AORI_5033(nudF) AORI_6540(nudF)

AJA:	AJAP_06260 AJAP_07300 AJAP_14340

AMQ:	AMETH_2700(nudF)

AMYC:

CU254_22330 CU254_31210

AMYB:

BKN51_17590

AAB:	A4R43_14200 A4R43_22280

AMYY:

YIM_00730(nudF1) YIM_06460(nudF2) YIM_31365(nudF3)

AORI:

SD37_24765

AACD:

LWP59_12075

APRT:

MUY14_05825

AROO:

NQK81_41705

ATHM:

L1857_16295

PDX:	Psed_1703 Psed_3814

PSEA:

WY02_10745

PSEE:

FRP1_03440 FRP1_13730 FRP1_17870

PSEH:

XF36_06065 XF36_14015 XF36_19325

PSEQ:

AD006_11050 AD006_21405 AD006_31250

PECQ:

AD017_00985 AD017_04905 AD017_18880 AD017_29985

PHH:	AFB00_04650 AFB00_08895 AFB00_23885

PAUT:

Pdca_40620 Pdca_54510

PBRO:

HOP40_14565 HOP40_27615

PPEL:

H6H00_14070 H6H00_25420

APRE:

CNX65_04925 CNX65_08290 CNX65_27060 CNX65_30145

AMI:	Amir_0978 Amir_1659 Amir_5434 Amir_6125

SESP:

BN6_65730 BN6_73350

SSYI:

EKG83_37270 EKG83_40950

KAL:	KALB_6435 KALB_7584

KPHY:

AOZ06_15445 AOZ06_46210 AOZ06_48485

LED:	BBK82_20795 BBK82_24765 BBK82_46930

AHM:	TL08_07400 TL08_18015

ACTI:

UA75_07115 UA75_21995

ACAD:

UA74_07120 UA74_21520

AHG:	AHOG_06840(nudF1) AHOG_18975(nudF2)

ACTA:

C1701_03955 C1701_16935 C1701_17740

ALO:	CRK56027 CRK58008 CRK59008 CRK59417

PMAD:

BAY61_21210 BAY61_25380

SACE:

GIY23_14560 GIY23_18030

ACTU:

Actkin_02066(nudF_1)

STP:	Strop_1921

SAQ:

Sare_1912

MAU:	Micau_2417

MIL:

ML5_6050

MICB:

MicB006_5499

MTUA:

CSH63_12645

MICH:

FJK98_11395

MTEM:

GCE86_05720

MCAB:

HXZ27_15225

MSAG:

GCM10017556_47630

VMA:	VAB18032_15420

MCRA:

ID554_01680

VER:	HUT12_11505

MENO:

Jiend_04880

ASE:

ACPL_6345

AMS:	AMIS_60880

ACTN:

L083_5807

AFS:

AFR_29890

ACTS:

ACWT_6213

AIH:	Aiant_20070

ACTR:

Asp14428_73170

PLK:	CIK06_11940

PLAB:

C6361_35985

PLAT:

C6W10_21980

PFLA:

Pflav_008430

PSUU:

Psuf_064940

ATL:	Athai_30500 Athai_60800

ASER:

Asera_44060

PRY:	Prubr_18110 Prubr_49770

CATI:

CS0771_37620 CS0771_65160

DVC:	Dvina_41530

DFU:	Dfulv_36410

DROS:

Drose_22395 Drose_27265

DAUR:

Daura_35210 Daura_40225

DMAT:

Dmats_36225

NHY:	JQS43_12780

CCAZ:

COUCH_14030

CAI:	Caci_5410 Caci_6699

SNA:

Snas_4431

NAV:	JQS30_08725

GLY:	K3N28_00345

AHE:

Arch_0939

ARCA:

HC352_04540

APHO:

JTE88_04795

MCU:	HMPREF0573_11884

TPY:	CQ11_00070

TPYO:

X956_05205

TBW:	NCTC13354_00012(nudF)

TPEC:

HLG82_04360

ACTT:

DDD63_06425

AMY:	ADJ76_03480

SOO:	FBF35_04965

STUC:

G5S47_03355

ACQ:	AM609_07770

AOS:	AXE84_10050

ACTP:

B6G06_03695

ACTC:

CHIBA101_1461

ACTO:

C3V41_02420

ANE:	ATCC27039_11410

AHW:	NCTC11636_00643(nudF)

ACTZ:

CWT12_04755

AIR:	NCTC12972_00677(nudF)

ASLA:

NCTC11923_02114(nudF)

AVC:	NCTC10951_00985(nudF)

AWE:	JG540_04405

AMAM:

HPC72_06075

AREP:

ID810_05400

AGH:	M3I41_06535

AVU:	BK816_05480 BK816_08145

FSL:	EJO69_03230

FLH:	EJ997_04030

WIK:	H8R18_03575

WNE:	PIG85_04870

BLA:

BLA_1489

BLC:	Balac_0978

BLT:	Balat_0978

BBB:

BIF_01788

BBC:

BLC1_0935

BNM:	BALAC2494_00432

BLV:

BalV_0942

BLW:

W7Y_0979

BLS:

W91_1001

BANI:

Bl12_0913

BANL:

BLAC_04940

BNI:	BANAN_04830

BANM:

EN10_04960

BAST:

BAST_1167

AEY:	CDG81_05255 CDG81_10005

EKE:	EK0264_00530

JTL:	M6D93_09000

CWO:

Cwoe_3089

AYM:	YM304_24910(nudF)

ATQ:	GH723_09055

AQZ:	KSP35_04190

IAM:	HC251_10615

ERZ:	ER308_19795

EUZ:	DVS28_a1883

TRO:

trd_1187

TRA:

Trad_1612

MSV:	Mesil_2029

CCZ:	CCALI_01382

CCOT:

CCAX7_33990

PLH:	VT85_02420(nudF_1)

IPA:

Isop_0097

ADIN:

H7849_05020

CPI:

Cpin_2928

CHIT:

FW415_13875

CHIH:

GWR21_29220

CHF:	KTO58_05390

NKO:	Niako_1529

NSO:	NIASO_02645

NIA:	A8C56_05800

ARB:	A9P82_01450

ARK:	D6B99_04930

AGI:	FSB73_15900

ARAC:

E0W69_011885

PGIN:

FRZ67_02240

AUP:	AsAng_0045320

PEX:	IZT61_15450

PMUO:

LOK61_19090

PRK:	H9N25_22090

PSN:	Pedsa_2859

MGIN:

FRZ54_00875

MMAB:

HQ865_23055

MROB:

HH214_07970

MJJ:	PQO05_02270

AGD:	FRZ59_03485

EMAI:

KZP23_10990

MDA:	IPZ59_18800

SRD:	SD10_10740

SRHO:

HH216_15860

AANH:

G9X63_09800

ALEN:

G9X62_09940

CHRW:

KA713_06440

DSN:	HWI92_03260

DYC:	NFI80_05425

MAQA:

LAG90_03345

HYM:	N008_13215

HYG:	AUC43_10345

HYP:	A0257_09915

HYZ:	AXW84_16070

HNV:	DDQ68_10860

HYH:	D3Y59_00170

HYJ:	FHG12_13655

HQI:	H9L05_11945

HBN:	GUY19_19075

HTS:	HMJ29_02105

HMT:	MTP16_23225

HTB:	MTX78_17410

HYK:	O9Z63_12200

RUF:	TH63_12310

RTI:	DC20_02870

NIB:	GU926_07180

CHK:	D4L85_04500

FUV:	JR347_01090

REK:	N6H18_11975

PTAN:

CRYO30217_01391(nudF)

CLZ:	BIU88_03965

CPH:	Cpha266_1677

CLI:

Clim_1544

PLT:

Plut_1344

PROC:

Ptc2401_00708(nudF)

PROS:

CHL67_03940

CTS:

Ctha_0622

» show all

Reference

1 [PMID:16002790]

Authors

Ishibashi T, Hayakawa H, Ito R, Miyazawa M, Yamagata Y, Sekiguchi M

Title

Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.

Journal

Nucleic Acids Res 33:3779-84 (2005)
DOI:10.1093/nar/gki682

Sequence

[hsa:11164]

Reference

2 [PMID:12717453]

Authors

Ishibashi T, Hayakawa H, Sekiguchi M

Title

A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.

Journal

EMBO Rep 4:479-83 (2003)
DOI:10.1038/sj.embor.embor838

Sequence

[hsa:11164]

Reference

3 [PMID:19699693]

Authors

Kamiya H, Hori M, Arimori T, Sekiguchi M, Yamagata Y, Harashima H

Title

NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity.

Journal

DNA Repair (Amst) 8:1250-4 (2009)
DOI:10.1016/j.dnarep.2009.07.011

Reference

4 [PMID:21389046]

Authors

Ito R, Sekiguchi M, Setoyama D, Nakatsu Y, Yamagata Y, Hayakawa H

Title

Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein.

Journal

J Biochem 149:731-8 (2011)
DOI:10.1093/jb/mvr028

Reference

5 [PMID:17052728]

Authors

Zha M, Zhong C, Peng Y, Hu H, Ding J

Title

Crystal structures of human NUDT5 reveal insights into the structural basis of the substrate specificity.

Journal

J Mol Biol 364:1021-33 (2006)
DOI:10.1016/j.jmb.2006.09.078

Sequence

[hsa:11164]

Reference

6 [PMID:22556419]

Authors

Takagi Y, Setoyama D, Ito R, Kamiya H, Yamagata Y, Sekiguchi M

Title

Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2.

Journal

J Biol Chem 287:21541-9 (2012)
DOI:10.1074/jbc.M112.363010

Sequence

[hsa:79873]

Other DBs

ExplorEnz - The Enzyme Database:

3.6.1.58

IUBMB Enzyme Nomenclature:

3.6.1.58

ExPASy - ENZYME nomenclature database:

3.6.1.58

BRENDA, the Enzyme Database:

3.6.1.58

DBGET integrated database retrieval system