KEGG   ENZYME: 3.6.1.59
Entry
EC 3.6.1.59                 Enzyme                                 
Name
5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase;
DcpS;
m7GpppX pyrophosphatase;
m7GpppN m7GMP phosphohydrolase;
m7GpppX diphosphatase;
m7G5'ppp5'N m7GMP phosphohydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] N7-methylguanosine 5'-phosphate phosphohydrolase
Reaction(IUBMB)
a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] + H2O = N7-methylguanosine 5'-phosphate + a 5'-diphospho-[mRNA]
Reaction(KEGG)
(other) R04368
Substrate
5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] [CPD:C02339];
H2O [CPD:C00001]
Product
N7-methylguanosine 5'-phosphate;
5'-diphospho-[mRNA] [CPD:C02100]
Comment
The enzyme removes (decaps) the N7-methylguanosine 5-phosphate cap from an mRNA degraded to a maximal length of 10 nucleotides [3,6]. Decapping is an important process in the control of eukaryotic mRNA degradation. The enzyme functions to clear the cell of cap structure following decay of the RNA body [2]. The nematode enzyme can also decap triply methylated substrates, 5'-(N2,N2,N7-trimethyl 5'-triphosphoguanosine)-[mRNA] [4].
History
EC 3.6.1.59 created 2012, modified 2013
Orthology
K12584  m7GpppX diphosphatase
Genes
HSA28960(DCPS)
PTR451655(DCPS)
PPS100974902(DCPS)
GGO101145375(DCPS)
PON100441593(DCPS)
NLE100601639(DCPS)
HMH116477152(DCPS)
MCC717749(DCPS)
MCF102120410(DCPS)
MTHB126934865
MNI105476240(DCPS)
CSAB103248789(DCPS)
CATY105582621(DCPS)
PANU100997052(DCPS) 116268623
TGE112606568(DCPS)
MLEU105554693(DCPS)
RRO115893594(DCPS)
RBB108542316(DCPS)
TFN117080847(DCPS)
PTEH111540312(DCPS)
CANG105506480(DCPS)
CJC100410129(DCPS)
SBQ101040093(DCPS)
CIMI108302656(DCPS)
CSYR103270563(DCPS)
MMUR105875361(DCPS)
LCAT123640988(DCPS)
PCOQ105825728(DCPS)
OGA100943901(DCPS)
MMU69305(Dcps)
MPAH110327897(Dcps)
RNO266605(Dcps)
MCOC116073396(Dcps)
ANU117698922(Dcps)
MUN110555278(Dcps)
CGE100761162(Dcps)
MAUA101839621(Dcps)
PROB127231492(Dcps)
PLEU114699776(Dcps)
MORG121451585(Dcps)
MFOT126487313
AAMP119809759(Dcps)
NGI103735398(Dcps)
HGL101715664(Dcps)
CPOC100731112(Dcps)
CCAN109698463(Dcps)
DORD105980540(Dcps)
DSP122104200(Dcps)
PLOP125349498(Dcps)
NCAR124960416
OCU100338456 108175353
OPI101528582(DCPS)
TUP102484523(DCPS)
GVR103604873
CFA609536(DCPS)
CLUD112671089(DCPS)
VVP112920265(DCPS)
VLG121500392(DCPS)
NPO129497217(DCPS)
AML100470542(DCPS)
UMR103660653(DCPS)
UAH113259881(DCPS)
UAR123792726(DCPS)
ELK111153955
LLV125078120
MPUF101671617(DCPS) 101692260
MNP132026137(DCPS)
NVS122912425(DCPS)
ORO101375494(DCPS)
EJU114222324(DCPS)
ZCA113914775(DCPS)
MLX118013384(DCPS)
NSU110586213(DCPS)
LWW102735441(DCPS)
FCA101088950(DCPS)
PYU121035615(DCPS)
PCOO112865455(DCPS)
PBG122483131(DCPS)
LRUF124505833
PTG102969848(DCPS)
PPAD109250349(DCPS)
PUC125939126
AJU106974920
BTA282640(DCPS)
BOM102278216(DCPS)
BBUB102407028(DCPS)
BBIS104980710(DCPS)
CHX102190586(DCPS)
OAS101114475(DCPS)
BTAX128068938(DCPS)
ODA120874444(DCPS)
CCAD122431227(DCPS)
MBEZ129548943(DCPS)
SSC396689(DCPS)
CFR102519944(DCPS)
CBAI105074190(DCPS)
CDK105094264(DCPS)
VPC102540499(DCPS)
BACU103009141(DCPS)
LVE103078579(DCPS)
OOR101285628(ST3GAL4)
DLE111165468(DCPS)
PCAD102979201(DCPS)
PSIU116758628(DCPS)
NASI112396876(DCPS)
ECB100064530(DCPS)
EPZ103549022(DCPS)
EAI106834017(DCPS)
MYB102251721(DCPS)
MYD102774242(DCPS)
MLF102433128(DCPS)
MNA107530600(DCPS)
EFUS129147024(DCPS)
HAI109391391(DCPS)
DRO112301771(DCPS)
SHON118981478(DCPS)
AJM119041088(DCPS)
PDIC114509652(DCPS)
PHAS123832565(DCPS)
MMF118640052(DCPS)
RFQ117017717(DCPS)
PALE102879340(DCPS)
PGIG120610444(DCPS)
PVP105296798(DCPS)
RAY107507803(DCPS)
MJV108399048(DCPS)
TOD119240833(DCPS)
SARA101553010(DCPS)
LAV100656614(DCPS)
TMU101343348
ETF101642506(DCPS)
DNM101439940(DCPS)
MDO100019554(DCPS)
GAS123238918(DCPS)
SHR100935301(DCPS)
AFZ127554824
PCW110218146(DCPS)
OAA100089721(DCPS) 114815064
GGA419716(DCPS)
PCOC116233046(DCPS)
MGP100544934(DCPS)
CJO107324199(DCPS)
TPAI128087525(DCPS)
LMUT125703750(DCPS)
NMEL110387711(DCPS)
APLA101792448(DCPS)
ACYG106040558(DCPS)
CATA118252380(DCPS)
AFUL116497790(DCPS)
TGU100217679(DCPS)
LSR110468147(DCPS)
SCAN103822804(DCPS)
PMOA120508342(DCPS)
OTC121340875(DCPS)
PRUF121360569(DCPS)
GFR102035714(DCPS)
FAB101821090(DCPS)
OMA130262570(DCPS)
PHI102102643(DCPS)
PMAJ107214434(DCPS)
CCAE111939373(DCPS)
CCW104692219(DCPS)
CBRC103618540(DCPS)
ETL114064607(DCPS)
ZAB102060588(DCPS)
ACHL103808280(DCPS)
SVG106860767(DCPS)
MMEA130583010(DCPS)
HRT120762575(DCPS)
FPG101910550(DCPS)
FCH102047627(DCPS)
CLV106145844(DCPS)
EGZ104129234(DCPS)
NNI104016674(DCPS)
PLET104614658(DCPS)
EHS104516455(DCPS)
PCAO104040971(DCPS)
ACUN113488429(DCPS)
TALA104366911(DCPS)
PADL103916421(DCPS)
AFOR103893772(DCPS)
ACHC115344675(DCPS)
HALD104314174(DCPS)
HLE104840438(DCPS)
AGEN126038321
GCL127025823
CCRI104167233(DCPS)
CMAC104482716(DCPS)
BREG104636074(DCPS)
FGA104081191(DCPS)
GSTE104259308(DCPS)
MNB103779874(DCPS)
OHA104335821(DCPS)
NNT104399498(DCPS)
SHAB115616356(DCPS)
DPUB104308644(DCPS)
PGUU104465727(DCPS)
ACAR104517559(DCPS)
CPEA104398056(DCPS)
AVIT104273879(DCPS)
CVF104291577(DCPS)
RTD128918536(DCPS)
CUCA104066052(DCPS)
TEO104375758(DCPS)
BRHI104492590(DCPS)
AAM106498500(DCPS)
AROW112968909(DCPS)
NPD112947250(DCPS)
DNE112981575(DCPS)
SCAM104148685(DCPS)
ASN102384846(DCPS)
AMJ102564856(DCPS)
CPOO109317986(DCPS)
GGN109291832(DCPS)
PSS102454492(DCPS)
CMY102947472(DCPS)
CCAY125625495(DCPS)
DCC119846820(DCPS)
CPIC101942376(DCPS)
TST117868609(DCPS)
CABI116818781(DCPS)
MRV120375409(DCPS)
ACS100567351(dcps)
PVT110088810(DCPS)
PBI103066095(DCPS)
PMUR107292369(DCPS)
CTIG120313957(DCPS)
TSR106556634
PGUT117668198(DCPS)
APRI131204050(DCPS)
PTEX113441918(DCPS)
NSS113421017(DCPS)
VKO123027069(DCPS)
PMUA114585279(DCPS)
PRAF128402883(DCPS)
ZVI118096820(DCPS)
HCG128334037(DCPS)
GJA107119892(DCPS)
STOW125441714(DCPS)
EMC129342301(DCPS)
XLA394400(dcps.L)
XTR100216298(dcps)
NPR108794017(DCPS)
RTEM120915578(DCPS)
BBUF121000890(DCPS)
BGAR122926748(DCPS)
MUO115482007(DCPS)
GSH117347760(DCPS)
DRE402850(dcps)
SRX107758690
SANH107653712 107671566
SGH107577914 107577915 107583391(dcps)
CCAR109098029(dcps)
CAUA113110030(dcps)
CGIB127966267
PTET122331748(dcps)
LROH127171769(dcps)
OMC131548287(dcps)
PPRM120482632(dcps)
MAMB125262283(dcps)
CIDE127520619
MASI127433327
TROS130546261(dcps)
MANU129446647(dcps)
IPU108276556
IFU128620177(dcps)
PHYP113544859(dcps)
SMEO124393800(dcps)
TFD113650286(dcps)
AMEX103034238(dcps)
CMAO118825077(dcps)
EEE113580713(dcps)
CHAR122132060(dcps)
TRU115252309 445993(dcps)
TFS130531034(dcps)
TNGGSTEN00010712G001
LCO104932284(dcps)
NCC104948373(dcps)
CGOB115015165(dcps)
ELY117260698(dcps)
EFO125894454(dcps)
PLEP121948156(dcps)
SLUC116036614(dcps)
ECRA117951987(dcps)
ESP116685945(dcps)
PFLV114562779(dcps)
GAT120817091(dcps)
PPUG119210912(dcps)
AFB129090339(dcps)
CLUM117737371(dcps)
MSAM119889163(dcps)
SCHU122879857(dcps)
CUD121516485(dcps)
ALAT119007404(dcps)
MZE101484626(dcps)
ONL100707834(dcps)
OAU116328134(dcps)
OLA101158538(dcps)
OML112153019(dcps)
XMA102224706(dcps)
XCO114139758(dcps)
XHE116714962(dcps)
PRET103471025(dcps)
PFOR103149293(dcps)
PLAI106957967(dcps)
PMEI106928928(dcps)
GAF122837204(dcps)
CVG107093834(dcps)
CTUL119797263(dcps)
GMU124860497(dcps)
NFU107382541(dcps)
KMR108240022(dcps)
ALIM106533196(dcps)
NWH119429281
AOCE111567332(dcps)
MCEP125008146(dcpS)
CSEM103391261
POV109627365(dcps)
SSEN122761366 122778794
HHIP117769807(dcps)
HSP118112809(dcps)
LCF108878927
SDU111226662(dcps)
SLAL111646433(dcps)
XGL120785385(dcps)
HCQ109524308(dcps)
SSCV125981374
BPEC110172173(dcps)
MALB109957539(dcps)
BSPL114864956(dcps)
SASA106603769(dcps)
STRU115154057(dcps)
OTW112228342(dcps)
OMY110533428(dcps)
OGO124013255(dcps)
ONE115136120(dcps)
OKI109872891(dcps)
OKE118389860(dcps)
SALP111950644(dcps)
SNH120056935(dcps)
CCLU121579256(dcps)
ELS105028750(dcps)
SFM108921345(dcps)
PKI111860786(dcps)
AANG118235091(dcps)
LOC102688135(dcps)
PSPA121309528(dcps)
ARUT117397254 117966544
PSEX120535903(dcps)
LCM102361941(DCPS) 102366682
CMK103180338(dcps)
RTP109916492(dcps)
CPLA122540746(dcps)
LERI129712456(dcps)
BFO118421283
BBEL109484414
CIN100175982
SPU587255
LPIC129256090 129256091 129258059
APLC110983458
AJC117120747
SKO100367637
DMEDmel_CG2091(CG2091)
DER6552743
DSE6614022
DSIDsimw501_GD19585(Dsim_GD19585)
DYADyak_GE24141
DAN6501420
DSR110187776
DPO4802058
DPE6588316
DMN108156456
DWI6650349
DGR6564358
DMODmoj_GI24670
DAZ108608805
DNV108650800
DHE111603030
DVI6630459
CCAT101461473
BOD106627741
RZE108358893
TDA119684907
MDE101893363
SCAC106096354
LCQ111682688
LSQ119609226
ECOE129939047
HIS119659335
AGAAgaP_AGAP010712
ACOZ120955081
AARA120903292
AMER121598368
AFUN125771109
AALI118464756
AAG5571000
AALB109413098 109418537 115257603
CQUCpipJ_CPIJ005586
CPII120414888
CNS116338985
AME552284
ACER107999990
ALAB122716957
ADR102677547
AFLR100868207
BIM100746156
BBIF117217115
BVK117236526
BVAN117154605
BTER100643261
BAFF126925590
BPYO122576764
FVI122530554
CCAL108630216
OBB114872246
MGEN117221088
NMEA116425822
CGIG122397240
SOC105202710
MPHA105830142
AEC105153426
ACEP105619523
PBAR105425029
VEM105564814
HST105187533
DQU106746690
CFO105258276
FEX115238894
LHU105678394
PGC109863073
OBO105276707
PCF106787996
PFUC122516956
VPS122628708
VCRB124424832
NVI100121865
CSOL105364356
TPRE106655657
LHT122508079
LBD127277312
MDL103577054
CGLO123269451 123274668 123274678
FAS105273354
DAM107046049
AGIF122860296
CINS118072178
VCAN122410725
CCIN107270176
DSM124414639
NPT124222985
NFB124186169
NLO107222367
NVG124308674
TCA658490
SOY115882392 115882986
AGRG126747304
ATD109602175
CSET123316277
AGB108906051
NVL108563755
APLN108736635
PPYR116180940
OTU111421559
BMOR101739862
BMAN114248421
MSEX115452897 119188988
DPLKGM_212538
BANY112045047
MJU123878174
NIQ126778532
VCD124540723
MCIX123667645
PMAC106720528
PPOT106100188
PXU106125816
PRAP111000036
PBX123720445
PNAP125052164
ZCE119835975
CCRC123703805
LSIN126976086
HAW110381189 126056883
HZE124643006
TNL113505511
SLIU111357993
PXY105387163 105397676
PGW126378148
CFEL113385764
CCRN123291584
API100163679(Dcps)
DNX107168087
AGS114129532
RMD113555575
ACOO126835247
BTAB109035356
DCI103511802
CLEC106665736
HHAL106684577
HVI124365052
PHUPhum_PHUM465990
FOC113210192
TPAL117647155
ZNE110833667
CSEC111866175
SGRE126321962
IEL124166409
FCD110843464 110853186 110853187
DPXDAPPUDRAFT_49874
DMK116928537
DPZ124311281
PVM113809607
PJA122243272 122264295
PCHN125045271
PMOO119575096
HAME121863847
PCLA123755412 123772615
CQD128691899
PTRU123511551
ESN127008376
HAZT108671885 108682239 108682718
EAF111711782
PPOI119098349 119098569
DSV119431036
RSAN119407265
RMP119163629
VDE111244496
VJA111267145
TUT107359431
DPTE113797724
DFR124500178
CSCU111623446
PTEP107444564 107455807
UDV129216056 129227746 129232737
SDM118188497 118197694
LPOL106459581
PMEO129599286
CELCELE_Y113G7A.9(dcs-1)
CBRCBG_12933(Cbr-dcs-1)
CRQGCK72_022032
NAINECAME_15462
BMYBM_BM7299(Bma-dcs-1)
LOALOAG_09879
TSPTsp_13171
HROHELRODRAFT_70549
LGILOTGIDRAFT_234493
PCAN112556716
BGT106066742
GAE121390407
HRF124124479
HRJ124285726
CRG105342540
CVN111108701
CANU128160501
OED125653336
PMAX117319178 117331654
MCAF127705187
MMER123528945
DPOL127831949
OBI106868479
OSN115217210
LAK106179651
SMMSmp_163300
SHXMS3_00003873
OVIT265_04563
EGLEGR_00336
NVE5497139 5512603
EPA110233505
ATEN116297305
ADF107337033
AMIL114975814
PDAM113666852
SPIS111331430
DGT114521478 114540626
XEN124446429
HMG100205537
HSY130655151
TADTRIADDRAFT_18652
AQU100632526
CRECHLRE_10g432650v5
VCNVOLCADRAFT_109749
CSLCOCSUDRAFT_18391
OLUOSTLU_34772
OTAOT_ostta09g00310
BPGBathy12g00560
MISMICPUN_99594
MPPMICPUCDRAFT_38692
SCEYLR270W(DCS1)
SEUBDI49_3779
SPAOSPAR_L02940
AGOAGOS_AGR268W
ERCEcym_3126
KLAKLLA0_F20229g
KMXKLMA_40182(DCS1)
LTHKLTH0G15488g
VPOKpol_1035p6 Kpol_1042p10
ZROZYRO0D14146g
CGRCAGL0C03113g
NCSNCAS_0D02700(NCAS0D02700) NCAS_0F00320(NCAS0F00320)
NDINDAI_0I02210(NDAI0I02210) NDAI_0K02850(NDAI0K02850)
TPFTPHA_0F02580(TPHA0F02580) TPHA_0K01170(TPHA0K01170)
TBLTBLA_0A09660(TBLA0A09660) TBLA_0G00540(TBLA0G00540)
TGBHG536_0H04180
TDLTDEL_0G04070(TDEL0G04070)
KAFKAFR_0A05030(KAFR0A05030) KAFR_0G02510(KAFR0G02510)
KNGKNAG_0F02850(KNAG0F02850) KNAG_0M01030(KNAG0M01030)
ZMKHG535_0G02535
PPAPAS_chr3_0273
DHADEHA2F22000g
PICPICST_46357
PGUPGUG_00368
SPAASPAPADRAFT_144541
LELLELG_05459
CALCAALFM_C701190WA(CaO19.6901)
CTPCTRG_04851
COTCORT_0H00470
CDUCD36_71050
CTENCANTEDRAFT_116751
YLIYALI0E08074g YALI0F31141g
CLUCLUG_04283
CLUSA9F13_04g02376
CAURCJI96_0003380
PKZC5L36_0A01220
BNNFOA43_004639
BBRXBRETT_001771
OPAHPODL_02831
SLUDSCDLUD_000903
NCRNCU06998
SMPSMAC_07057
PANPODANSg3717
TTTTHITE_2092369
MTMMYCTH_2096067
CTHRCTHT_0038110
MGRMGG_15696
PPEIPpBr36_00933
PGRIPgNI_04095
TMNUCRPA7_5533
SSCKSPSK_00555
FGRFGSG_09810
FPUFPSE_00831
FPOAFPOAC1_011827
FVNFVRRES_12891
FVRFVEG_06425
FOXFOXG_08246
NHENECHADRAFT_103460
FFCNCS54_00266500
FMUJ7337_004365
TRETRIREDRAFT_55669
TRRM419DRAFT_70557
MAWMAC_06415
MAJMAA_05059
PCHMVFPPC_09052
AMUSLMH87_006319
PLJVFPFJ_00886
PTKZJDV02_007770
VALVDBG_01246
VDAVDAG_08015
CFJCFIO01_00172
CLUPCLUP02_18001
CHIGCH63R_13731
SAPOSAPIO_CDS7504
ELAUCREL1_10900
PFYPFICI_04628
BFUBCIN_12g04480
PSCOLY89DRAFT_568166
GLZGLAREA_10948
ANIAN7492.2
AFMAFUA_2G05580
ACTACLA_089120
NFINFIA_082300
AORAO090001000669
ANGAn02g13910
AFVAFLA_012801
ALUCAKAW2_11174S
ACHEACHE_80324A
APUUAPUU_80553S
PCSPc22g08720
PDPPDIP_87100
POUPOX_d05855
TMFEYB26_005803
TRGTRUGW13939_06313
CIMCIMG_00761
CPWCPC735_055330
UREUREG_00738
PBLPAAG_02255
PBNPADG_05393
ABEARB_03877
TVETRV_06634
AJEHCAG_00981
BGHBDBG_08933
PNOSNOG_14047
PTEPTT_17752
BZECOCCADRAFT_92931
BSCCOCSADRAFT_22003
BORCOCMIDRAFT_31931
AALTCC77DRAFT_1020611
ARABEKO05_0009276
ZTRMYCGRDRAFT_75774
PFJMYCFIDRAFT_83821
FFUCLAFUR5_10963
CBETCB0940_07016
BCOMBAUCODRAFT_78928
NPAUCRNP2_5042
TMLGSTUM_00010012001
SPOSPBP4H10.20(nhm1)
SOMSOMG_00721(nhm1)
CNECNN00850
CNBCNBN0860
CNGCNAG_06359
CGICGB_N1270C
TMSTREMEDRAFT_33242
TASAA1Q1_03343
CCACCcaHIS019_0510620(CcaverHIS019_0510620)
PPLPOSPLDRAFT_134967 POSPLDRAFT_93518
TVSTRAVEDRAFT_129979
DSQDICSQDRAFT_112292
PCOPHACADRAFT_254246
HIRHETIRDRAFT_329514
PSQPUNSTDRAFT_134327
ADLAURDEDRAFT_174660
FMEFOMMEDRAFT_77962
GTRGLOTRDRAFT_139451
RSXRhiXN_08517
LBCLACBIDRAFT_239274
CCICC1G_08031
ABPAGABI1DRAFT114139(AGABI1DRAFT_114139)
ABVAGABI2DRAFT193987(AGABI2DRAFT_193987)
PCUBJR316_0006943
MRRMoror_14113
MOREE1B28_007222
SCMSCHCO_02636681(SCHCODRAFT_02636681)
CPUTCONPUDRAFT_82827
SLASERLADRAFT_433284
WSEWALSEDRAFT_61549
WICJ056_002865
UMAUMAG_10873
PFPPFL1_02476
SGRAEX895_003847
MGLMGL_3756
MRTMRET_1723
MSYMMSY001_0084
PGRPGTG_06620
PTRCPtA15_16A121
PSTRPst134EA_028954
MLRMELLADRAFT_45088
ECUECU10_1710
EINEint_101680
EHEEHEL_101750
EROEROM_101610
NCENCER_101753
EHIEHI_169590(223.t00003)
EDIEDI_201750
EIVEIN_154880 EIN_406030
ACANACA1_088590
TETTTHERM_000525059
PTMGSPATT00026816001
FCYFRACYDRAFT_211609
TPSTHAPSDRAFT_263371
AAFAURANDRAFT_13102
PIFPITG_00288 PITG_00291
PSOJPHYSODRAFT_316123 PHYSODRAFT_560555
SPARSPRG_07731
EHXEMIHUDRAFT_227266
GTTGUITHDRAFT_137339 GUITHDRAFT_146688 GUITHDRAFT_74405 GUITHDRAFT_79107 GUITHDRAFT_80213
 » show all
Reference
1  [PMID:16963086]
  Authors
Malys N, McCarthy JE
  Title
Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies.
  Journal
J Mol Biol 363:370-82 (2006)
DOI:10.1016/j.jmb.2006.08.015
  Sequence
[sce:YLR270W]
Reference
2  [PMID:18441014]
  Authors
Liu SW, Rajagopal V, Patel SS, Kiledjian M
  Title
Mechanistic and kinetic analysis of the DcpS scavenger decapping enzyme.
  Journal
J Biol Chem 283:16427-36 (2008)
DOI:10.1074/jbc.M800341200
Reference
3  [PMID:12198172]
  Authors
Liu H, Rodgers ND, Jiao X, Kiledjian M
  Title
The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases.
  Journal
EMBO J 21:4699-708 (2002)
DOI:10.1093/emboj/cdf448
  Sequence
[hsa:28960] [sce:YLR270W]
Reference
4  [PMID:14523240]
  Authors
van Dijk E, Le Hir H, Seraphin B
  Title
DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway.
  Journal
Proc Natl Acad Sci U S A 100:12081-6 (2003)
DOI:10.1073/pnas.1635192100
  Sequence
[hsa:28960] [sce:YLR270W]
Reference
5  [PMID:15769464]
  Authors
Chen N, Walsh MA, Liu Y, Parker R, Song H
  Title
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
  Journal
J Mol Biol 347:707-18 (2005)
DOI:10.1016/j.jmb.2005.01.062
  Sequence
[hsa:28960]
Reference
6  [PMID:15383679]
  Authors
Cohen LS, Mikhli C, Friedman C, Jankowska-Anyszka M, Stepinski J, Darzynkiewicz E, Davis RE
  Title
Nematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and  characterization of C. elegans scavenger DcpS.
  Journal
RNA 10:1609-24 (2004)
DOI:10.1261/rna.7690504
  Sequence
Reference
7  [PMID:22985415]
  Authors
Wypijewska A, Bojarska E, Lukaszewicz M, Stepinski J, Jemielity J, Davis RE, Darzynkiewicz E
  Title
7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.
  Journal
Biochemistry 51:8003-13 (2012)
DOI:10.1021/bi300781g
  Sequence
[ag:ADB92583] [cel:CELE_Y113G7A.9] [hsa:28960] [sce:YLR270W]
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.59
IUBMB Enzyme Nomenclature: 3.6.1.59
ExPASy - ENZYME nomenclature database: 3.6.1.59
BRENDA, the Enzyme Database: 3.6.1.59

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