KEGG   ENZYME: 3.6.1.68Help
Entry
EC 3.6.1.68                 Enzyme                                 

Name
geranyl diphosphate phosphohydrolase;
NUDX1 (gene name)
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
geranyl-diphosphate phosphohydrolase
Reaction(IUBMB)
geranyl diphosphate + H2O = geranyl phosphate + phosphate [RN:R11551]
Reaction(KEGG)
Substrate
geranyl diphosphate [CPD:C00341];
H2O [CPD:C00001]
Product
geranyl phosphate [CPD:C21203];
phosphate [CPD:C00009]
Comment
The enzyme, characterized from roses, is involved in a cytosolic pathway for the biosynthesis of free monoterpene alcohols that contribute to fragrance. In vitro the enzyme also acts on (2E,6E)-farnesyl diphosphate.
History
EC 3.6.1.68 created 2015 as EC 3.1.3.98, transferred 2016 to EC 3.6.1.68
Orthology
K20986  geranyl diphosphate phosphohydrolase
Genes
FVE: 101310019 101310310
PPER: 18792770
PMUM: 103341413
MDM: 103402740 103451694
PXB: 103929214 103946941
Taxonomy
Reference
1  [PMID:26138978]
  Authors
Magnard JL, Roccia A, Caissard JC, Vergne P, Sun P, Hecquet R, Dubois A, Hibrand-Saint Oyant L, Jullien F, Nicole F, Raymond O, Huguet S, Baltenweck R, Meyer S, Claudel P, Jeauffre J, Rohmer M, Foucher F, Hugueney P, Bendahmane M, Baudino S
  Title
PLANT VOLATILES. Biosynthesis of monoterpene scent compounds in roses.
  Journal
Science 349:81-3 (2015)
DOI:10.1126/science.aab0696
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.68
IUBMB Enzyme Nomenclature: 3.6.1.68
ExPASy - ENZYME nomenclature database: 3.6.1.68
BRENDA, the Enzyme Database: 3.6.1.68

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