KEGG   ENZYME: 3.6.1.8Help
Entry
EC 3.6.1.8                  Enzyme                                 

Name
ATP diphosphatase;
ATPase (ambiguous);
ATP pyrophosphatase;
adenosine triphosphate pyrophosphatase;
ATP diphosphohydrolase (ambiguous)
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
ATP diphosphohydrolase (diphosphate-forming)
Reaction(IUBMB)
ATP + H2O = AMP + diphosphate [RN:R00087]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013]
Comment
Also acts on ITP, GTP, CTP and UTP.
History
EC 3.6.1.8 created 1961
Pathway
ec00230  Purine metabolism
ec00240  Pyrimidine metabolism
Reference
1  [PMID:13061448]
  Authors
HEPPEL LA, HILMOE RJ.
  Title
Mechanism of enzymatic hydrolysis of adenosinetriphosphate.
  Journal
J Biol Chem 202:217-26 (1953)
Reference
2  [PMID:13058963]
  Authors
JOHNSON M, KAYE MA, HEMS R, KREBS HA.
  Title
Enzymic hydrolysis of adenosine phosphates by cobra venom.
  Journal
Biochem J 54:625-9 (1953)
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.8
IUBMB Enzyme Nomenclature: 3.6.1.8
ExPASy - ENZYME nomenclature database: 3.6.1.8
BRENDA, the Enzyme Database: 3.6.1.8
CAS: 37289-25-1

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