KEGG   ENZYME: 3.6.3.22Help
Entry
EC 3.6.3.22                 Enzyme                                 

Name
nonpolar-amino-acid-transporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (nonpolar-amino-acid-transporting)
Reaction(IUBMB)
ATP + H2O + nonpolar amino acidout = ADP + phosphate + nonpolar amino acidin [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
nonpolar amino acid
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
nonpolar amino acid
Comment
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Comprises bacterial enzymes that import Leu, Ile and Val.
History
EC 3.6.3.22 created 2000
Orthology
K10822  nonpolar-amino-acid-transporting ATPase
Genes
REH: H16_A1244(h16_A1244) H16_A1245(h16_A1245) H16_A1542(h16_A1542)
Taxonomy
Reference
1  [PMID:7569321]
  Authors
Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr.
  Title
Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.
  Journal
Res Microbiol 146:271-8 (1995)
DOI:10.1016/0923-2508(96)81050-3
Reference
2  [PMID:9889977]
  Authors
Saier MH Jr.
  Title
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
  Journal
Adv Microb Physiol 40:81-136 (1998)
Reference
3
  Authors
Griffiths, J.K. and Sansom, C.E.
  Title
The Transporter Factsbook, Academic Press, San Diego, 1998.
Other DBs
ExplorEnz - The Enzyme Database: 3.6.3.22
IUBMB Enzyme Nomenclature: 3.6.3.22
ExPASy - ENZYME nomenclature database: 3.6.3.22
BRENDA, the Enzyme Database: 3.6.3.22

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