KEGG   ENZYME: 3.6.4.11Help
Entry
EC 3.6.4.11                 Enzyme                                 

Name
nucleoplasmin ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to facilitate cellular and subcellular movement
BRITE hierarchy
Sysname
ATP phosphohydrolase (nucleosome-assembling)
Reaction(IUBMB)
ATP + H2O = ADP + phosphate [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009]
Comment
An acidic nuclear protein that is active in the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.
History
EC 3.6.4.11 created 2000
Reference
1  [PMID:8098530]
  Authors
Laskey RA, Mills AD, Philpott A, Leno GH, Dilworth SM, Dingwall C.
  Title
The role of nucleoplasmin in chromatin assembly and disassembly.
  Journal
Philos Trans R Soc Lond B Biol Sci 339:263-9; discussion 268-9 (1993)
DOI:10.1098/rstb.1993.0024
Reference
2  [PMID:8016655]
  Authors
Cote J, Quinn J, Workman JL, Peterson CL.
  Title
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex.
  Journal
Science 265:53-60 (1994)
DOI:10.1126/science.8016655
Reference
3  [PMID:8798787]
  Authors
Ito T, Tyler JK, Bulger M, Kobayashi R, Kadonaga JT.
  Title
ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster.
  Journal
J Biol Chem 271:25041-8 (1996)
DOI:10.1074/jbc.271.40.25041
Other DBs
ExplorEnz - The Enzyme Database: 3.6.4.11
IUBMB Enzyme Nomenclature: 3.6.4.11
ExPASy - ENZYME nomenclature database: 3.6.4.11
BRENDA, the Enzyme Database: 3.6.4.11

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