KEGG   ENZYME: 3.6.5.2
Entry
EC 3.6.5.2                  Enzyme                                 
Name
small monomeric GTPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on GTP to facilitate cellular and subcellular movement
Sysname
GTP phosphohydrolase (cell-regulating)
Reaction(IUBMB)
GTP + H2O = GDP + phosphate [RN:R00335]
Reaction(KEGG)
R00335
Substrate
GTP [CPD:C00044];
H2O [CPD:C00001]
Product
GDP [CPD:C00035];
phosphate [CPD:C00009]
Comment
A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of heterotrimeric G-protein GTPase (EC 3.6.5.1). They are involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies).
History
EC 3.6.5.2 created 2000 as EC 3.6.1.47, transferred 2003 to EC 3.6.5.2
Orthology
K07893  Ras-related protein Rab-6A/C/D
K07894  Ras-related protein Rab-6B
Genes
HSA: 150786(RAB6D) 51560(RAB6B) 5870(RAB6A) 84084(RAB6C)
PTR: 112207946 112208375 451413(RAB6A) 459601(RAB6C) 743801(RAB6B)
PPS: 100972007(RAB6A) 100984820(RAB6B) 100993436(RAB6D) 117979374(RAB6C) 129397342
GGO: 101127945(RAB6B) 101137787(RAB6A) 101146228(RAB6D) 115930603
PON: 100172563(RAB6A) 100174075(RAB6B) 100437604 100441942
PPYG: 129008546(RAB6A) 129022357 129031731 129033917(RAB6B)
NLE: 100581972(RAB6A) 100590410(RAB6B) 100601566(RAB6C)
HMH: 116461659(RAB6B) 116462967(RAB6C) 116476662(RAB6A)
SSYN: 129484615(RAB6A) 129491295(RAB6B)
MCC: 717431(RAB6B) 718717(RAB6A)
MCF: 102131067(RAB6B) 102132687(RAB6A)
MTHB: 126935231 126948161
MNI: 105468721(RAB6A) 105469883(RAB6B)
CSAB: 103241649(RAB6B) 103248019(RAB6A)
CATY: 105578769(RAB6A) 105586425(RAB6B)
PANU: 100998230(RAB6B) 101014479(RAB6A)
TGE: 112605643(RAB6A) 112618168(RAB6B)
MLEU: 105532138(RAB6B) 105551060(RAB6A)
RRO: 104665134(RAB6A) 104681624(RAB6B)
RBB: 108529877(RAB6B) 108543760(RAB6A)
TFN: 117080638(RAB6A) 117084167(RAB6B)
PTEH: 111539542(RAB6B) 111540867(RAB6A)
CANG: 105519612(RAB6A) 105523374(RAB6B)
CJC: 100390784(RAB6A) 100402553(RAB6B)
SBQ: 101041082(RAB6B)
CIMI: 108287359(RAB6B) 108307551(RAB6A)
ANAN: 105716511(RAB6B) 105720072(RAB6A)
CSYR: 103259907(RAB6B) 103267062(RAB6A)
MMUR: 105860353(RAB6A) 105872660(RAB6B)
LCAT: 123629041(RAB6B) 123641056(RAB6A)
ERUF: 138384021(RAB6A) 138386672(RAB6B)
PCOQ: 105811491(RAB6A) 105825646(RAB6B)
OGA: 100958383(RAB6B) 100963869(RAB6A)
MMU: 19346(Rab6a) 270192(Rab6b)
MCAL: 110297356(Rab6a) 110301938(Rab6b)
MPAH: 110316477(Rab6a) 110327946(Rab6b)
RNO: 363123(Rab6b) 84379(Rab6a)
MCOC: 116072200(Rab6b) 116102652(Rab6a)
ANU: 117693402(Rab6b) 117703725(Rab6a)
ASYL: 127665102(Rab6a) 127688647(Rab6b)
MUN: 110550793(Rab6a) 110565557(Rab6b)
CGE: 100761500(Rab6a) 100766955(Rab6b)
MAUA: 101827923(Rab6b) 101835328(Rab6a)
PROB: 127227976(Rab6a) 127237719(Rab6b)
PLEU: 114693529(Rab6b) 114698725(Rab6a)
PMAV: 102921961(Rab6a) 102923806(Rab6b)
MORG: 121463660(Rab6a) 121464204(Rab6b)
MFOT: 126488869 126500010
AAMP: 119809740(Rab6b) 119817562(Rab6a)
CNL: 130873240(Rab6b) 130879434(Rab6a)
NGI: 103748950(Rab6b) 103749833(Rab6a)
HGL: 101716700(Rab6a) 101720322(Rab6b)
CPOC: 100727333(Rab6b) 100735707(Rab6a)
CCAN: 109687715(Rab6b) 109694634(Rab6a)
DORD: 105984061(Rab6a) 105994543(Rab6b)
DSP: 122095613(Rab6b) 122114466(Rab6a)
DMER: 138815990(Rab6b) 138836417(Rab6a)
PLOP: 125342679(Rab6b) 125361248(Rab6a)
NCAR: 124958763 124993383
MMMA: 107135534(Rab6a) 107143382(Rab6b) 107159268
ITI: 101971808(Rab6b) 101973142(Rab6a)
OCU: 100339042 100359312
OPI: 101528066(RAB6B) 101530213(RAB6A)
OCZ: 121145506(RAB6A) 121145984(RAB6B)
TUP: 102476111(RAB6A) 102479049(RAB6B)
GVR: 103593156(RAB6B) 103595917(RAB6C)
CFA: 608330(RAB6A) 610830(RAB6B)
CLUD: 112661026(RAB6B) 112667439(RAB6A)
VVP: 112928667(RAB6A) 112932569(RAB6B)
VLG: 121476276(RAB6A) 121478929(RAB6B)
NPO: 129506688(RAB6A) 129507244(RAB6B)
AML: 100467098(RAB6B) 100474615(RAB6A)
UMR: 103678035(RAB6A) 103678988(RAB6B)
UAH: 113253951(RAB6B) 113269295(RAB6A)
UAR: 123788390(RAB6B) 123804247(RAB6A)
ELK: 111154943
LLV: 125078534 125104218
MPUF: 101674948(RAB6B) 101675160(RAB6A)
MNP: 132011802(RAB6B) 132024265(RAB6A)
MLK: 131807599(RAB6A) 131824555(RAB6B)
NVS: 122908930(RAB6B) 122912601(RAB6A)
ORO: 101374157(RAB6A) 101380926(RAB6B)
EJU: 114205674(RAB6B) 114218738(RAB6A)
ZCA: 113914170(RAB6A) 113918475(RAB6B)
MLX: 118003871(RAB6B) 118004261(RAB6A)
NSU: 110570735(RAB6B) 110593349(RAB6A)
LWW: 102726462(RAB6A) 102739326
FCA: 101087341(RAB6B) 101097017(RAB6A)
PYU: 121033696(RAB6B) 121039256(RAB6A)
PCOO: 112850026(RAB6B) 112865920(RAB6A)
PBG: 122483357(RAB6A) 122491974(RAB6B)
PVIV: 125174860(RAB6B) 125176572(RAB6A)
LRUF: 124504757 124526883
LGF: 123601187(RAB6A) 123611545(RAB6B)
AJU: 106977993 106987396
PTG: 102953120(RAB6B) 102963647(RAB6A)
PPAD: 109259345(RAB6B) 109267168(RAB6A)
PUC: 125921988 125937365
PLEZ: 122199245(RAB6A) 122230288(RAB6B)
HHV: 120222199(RAB6A) 120239542(RAB6B)
BTA: 526526(RAB6B) 616537(RAB6A)
BOM: 102277647(RAB6B) 102283096(RAB6A)
BIU: 109560213(RAB6B) 109569639(RAB6A)
BBUB: 102400943(RAB6A) 102403085(RAB6B)
BKE: 129644171(RAB6B)
BBIS: 104995104(RAB6A) 105001832(RAB6B)
CHX: 102170824(RAB6B) 102183164(RAB6A)
OAS: 101103262(RAB6A) 101116194(RAB6B) 114114036
BTAX: 128051629(RAB6B) 128060100(RAB6A)
CSUM: 138083047(RAB6B) 138093254(RAB6A)
ODA: 120857337(RAB6B) 120876753(RAB6A)
CCAD: 122445316(RAB6B) 122449483(RAB6A)
MREE: 136173426(RAB6B) 136174115(RAB6A)
OVR: 110125929(RAB6B) 110143192(RAB6A)
MBEZ: 129547684(RAB6B) 129554651(RAB6A)
SSC: 100522830(RAB6B) 100625022(RAB6A)
CFR: 102514701(RAB6B) 102524521(RAB6A)
CBAI: 105063253(RAB6B) 105083304(RAB6A)
CDK: 105085290(RAB6B) 105096914(RAB6A)
VPC: 102528945(RAB6A) 102540179(RAB6B)
BACU: 103002882(RAB6B) 103008406
BMUS: 118894971(RAB6B) 118899199(RAB6A) 118902815
LVE: 103089968(RAB6B)
OOR: 101272208 101273557(RAB6B) 101274368(RAB6A) 101290418
LALB: 132520435(RAB6B) 132526123(RAB6A)
GMF: 115841811(RAB6A) 115862079(RAB6B)
DDP: 132425003(RAB6B) 132429692(RAB6A) 132434337
DLE: 111179202(RAB6B) 111184840(RAB6A)
PCAD: 102979060(RAB6A) 102989918(RAB6B) 102995654
PSIU: 116753154(RAB6B) 116757477(RAB6A) 116761128
PPHC: 136122376(RAB6B) 136126349(RAB6A) 136131319
NASI: 112400478(RAB6B) 112411063(RAB6A)
ECB: 100065366(RAB6B) 100065545(RAB6A)
EPZ: 103546374(RAB6B) 103563363(RAB6A)
EAI: 106823200(RAB6B) 106831675(RAB6A)
MYB: 102245394(RAB6B) 102247363(RAB6A)
MYD: 102762716(RAB6A) 102773616(RAB6B)
MMYO: 118664664(RAB6A) 118668164(RAB6B)
MLF: 102429954(RAB6B) 102438346(RAB6A)
MDT: 132215550(RAB6B) 132240818(RAB6A)
MYUM: 139017326(RAB6A) 139022368(RAB6B)
PKL: 118712513(RAB6A) 118715326(RAB6B)
EFUS: 103293581(RAB6A) 103296437(RAB6B)
MNA: 107533684(RAB6A) 107546072(RAB6B)
DRO: 112309510(RAB6B) 112315957(RAB6A)
SHON: 118997557(RAB6B)
AJM: 119048278(RAB6B) 119051717(RAB6A)
PDIC: 114499631(RAB6A) 114501743(RAB6B)
PHAS: 123805485(RAB6A) 123830690(RAB6B)
MMF: 118627897(RAB6A) 118633582(RAB6B)
PPAM: 129072737(RAB6A) 129088004(RAB6B)
HAI: 109386304(RAB6A) 109389224(RAB6B)
RFQ: 117030011(RAB6A) 117036959(RAB6B)
PALE: 102881531(RAB6A) 102886974(RAB6B)
PGIG: 120582095(RAB6B) 120590329(RAB6A)
PVP: 105290786(RAB6B) 105303640(RAB6A)
RAY: 107508485(RAB6B) 107519128(RAB6A)
MJV: 108403033(RAB6B) 108403148(RAB6A)
TOD: 119255612(RAB6A) 119257757(RAB6B)
SARA: 101544464(RAB6A) 101548811(RAB6B)
SFUM: 130025071(RAB6A) 130030322(RAB6B)
SETR: 126012177(RAB6B) 126018295(RAB6A)
LAV: 100662892(RAB6B)
TMU: 101350730 101354688
ETF: 101661108(RAB6A) 101663682(RAB6B)
DNM: 101413255(RAB6B) 101438534(RAB6A)
MDO: 100011930(RAB6A) 100015979(RAB6B)
GAS: 123239306 123239431(RAB6B) 123240496(RAB6A)
SHR: 100916452(RAB6B) 100920278(RAB6A)
AFZ: 127542657 127554215 127555098
PCW: 110201050 110208189(RAB6B)
TVP: 118832681 118837554(RAB6A) 118838957(RAB6B) 118842363
PBRV: 138148249(RAB6A) 138177517(RAB6B)
MLAO: 141507286(RAB6B) 141508327(RAB6A)
OAA: 100074109(RAB6B) 100085646(RAB6A)
TACU: 119928217(RAB6B) 119941323(RAB6A)
GGA: 419063(RAB6A)
PCOC: 116237157(RAB6A)
TPAI: 128088649(RAB6A)
LMUT: 125692164(RAB6A)
NMEL: 110392141(RAB6A)
APLA: 101794886(RAB6A)
AACU: 137859906(RAB6A)
ACYG: 106042392(RAB6A)
CATA: 118260248(RAB6A)
AFUL: 116502410(RAB6A)
LSR: 110481505(RAB6A)
SCAN: 103818392(RAB6A)
PMOA: 120496533(RAB6A)
OTC: 121344694(RAB6A)
PRUF: 121349714(RAB6A)
ATRC: 139585288(RAB6A)
GFR: 102038596(RAB6A)
FAB: 101820518(RAB6A)
OMA: 130257648(RAB6A)
PHI: 102111450(RAB6A)
PMAJ: 107203980(RAB6A)
CCAE: 111942305(RAB6A)
CCW: 104698134(RAB6A)
CBRC: 103625230(RAB6A)
ACOE: 138116873(RAB6A)
ETL: 114071058(RAB6A)
ZAB: 102068831(RAB6A)
ZLE: 135455500(RAB6A)
ACHL: 103798991(RAB6A)
SVG: 106860732(RAB6A)
MMEA: 130574753(RAB6A)
HRT: 120748446(RAB6A)
SATI: 136375332(RAB6A)
CFAI: 136303764(RAB6A)
CCIC: 134058178(RAB6A)
FPG: 101913980(RAB6A)
FCH: 102051786(RAB6A)
CCRI: 104162693(RAB6A)
NNT: 104411849
SHAB: 115604092(RAB6A)
SURA: 141939893(RAB6A)
TALA: 104359902(RAB6A)
ACHC: 115353206(RAB6A)
HALD: 104316299(RAB6A)
HLE: 104837487(RAB6A)
AGEN: 126048251
HHAR: 128153594(RAB6A)
BBUT: 142041438(RAB6A)
GCL: 127021019
LDI: 104350371(RAB6A)
MNB: 103780445
DPUB: 104302411(RAB6A)
PPUS: 135175850(RAB6A)
EGZ: 104122449(RAB6A)
NNI: 104022715(RAB6A)
PCRI: 104038619(RAB6A)
PCAO: 104045683(RAB6A)
PARX: 142064151(RAB6A)
PADL: 103921118(RAB6A)
AFOR: 103904610(RAB6A)
FGA: 104076233(RAB6A)
CBOR: 142077964(RAB6A)
GSTE: 104257512(RAB6A)
CBOY: 140646647(RAB6A)
MAME: 142404446(RAB6A)
CLV: 102089354(RAB6A)
CNIC: 136000491(RAB6A)
MUI: 104538145(RAB6B)
PLET: 104622596(RAB6A)
CUCA: 104064113(RAB6A)
BREG: 104641796(RAB6A)
GAME: 129209978(RAB6A)
OHA: 104328312(RAB6A)
CPEA: 104389036(RAB6A)
CVF: 104291721(RAB6A)
RTD: 128910733(RAB6A)
CRID: 134512285(RAB6A)
LMIC: 141737506(RAB6A)
NARQ: 141472656(RAB6A)
AAM: 106490328(RAB6A) 106492635(RAB6B)
AROW: 112972258(RAB6B) 112975284(RAB6A)
NPD: 112944897(RAB6B) 112949183(RAB6A)
TGT: 104576418
DNE: 112989483 112989991(RAB6A)
SCAM: 104138947(RAB6B) 104147641
ASN: 102368625(RAB6A) 102380398(RAB6B)
AMJ: 102567285(RAB6B) 102568356(RAB6A)
CPOO: 109306895(RAB6A) 109315378(RAB6B)
GGN: 109291251(RAB6A)
PSS: 102460835(RAB6A)
CIZ: 142002728(RAB6A)
CMY: 102934782(RAB6A) 102943841(RAB6B)
CCAY: 125632007(RAB6A) 125642861(RAB6B)
LKP: 140907803(RAB6A) 140917466(RAB6B)
NDS: 141988827(RAB6A) 141994109(RAB6B)
DCC: 119857749(RAB6A) 119861897(RAB6B)
CPIC: 101932102(RAB6A) 101947322(RAB6B)
TST: 117871320(RAB6A) 117883298(RAB6B)
EOB: 135883716(RAB6B) 135895226(RAB6A)
CABI: 116818675(RAB6B)
MRV: 120372001(RAB6B) 120400593(RAB6A)
ACS: 100557260(rab6a) 100562013(rab6b)
ASAO: 132770741(RAB6B) 132772308(RAB6A)
PVT: 110070529(RAB6A) 110075289(RAB6B)
SUND: 121926031(RAB6B) 121926562(RAB6A)
PBI: 103058857(RAB6A) 103065094(RAB6B)
PMUR: 107295913
CTIG: 120309336(RAB6A) 120315574(RAB6B)
TSR: 106539252(RAB6B) 106555184(RAB6A)
PGUT: 117678070(RAB6A) 117678463(RAB6B)
PCAE: 139316340(RAB6A) 139317936(RAB6B)
APRI: 131199541(RAB6A) 131201137(RAB6B)
PTEX: 113436794(RAB6B) 113451777(RAB6A)
NSS: 113426936(RAB6A) 113429651(RAB6B)
VKO: 123025413(RAB6B) 123033516(RAB6A)
PMUA: 114595541(RAB6A) 114597724(RAB6B)
PRAF: 128412455(RAB6A) 128414493(RAB6B)
ZVI: 118084755(RAB6A) 118094081(RAB6B)
HCG: 128351496(RAB6B) 128351566(RAB6A)
GJA: 107113970(RAB6B) 107124060(RAB6A)
STOW: 125437710(RAB6B)
EMC: 129325531(RAB6A) 129332931(RAB6B)
XLA: 108710051 108717144(rab6b.L) 380198(rab6a.S) 444561(rab6b.S)
XTR: 100038231(rab6b) 394940(rab6a)
NPR: 108786112(RAB6B) 108800570(RAB6A)
RTEM: 120928794(RAB6A) 120936430(RAB6B)
ACAT: 141126787(RAB6A) 141139445(RAB6B)
PADS: 140323758(RAB6A) 140328224(RAB6B)
BBUF: 120996537(RAB6A) 120997600(RAB6B)
BGAR: 122931916(RAB6A) 122935357(RAB6B)
DTC: 141051570(RAB6A) 141091138(RAB6B)
HSQ: 130358251(RAB6A) 130361432(RAB6B)
PCOB: 134909111(RAB6B) 134996330(RAB6A)
PWL: 138249765(RAB6A)
MUO: 115468372(RAB6A)
GSH: 117362075(RAB6A)
DRE: 541339(rab6bb) 558900(rab6ba) 793785(rab6a)
SRX: 107717941 107718122 107722640 107741150 107743403 107752652
SANH: 107653754 107691568 107693724 107694122 107696768
SGH: 107552273 107564716 107583347(rab6a) 107589854
CCAR: 109053309 109064897 109064898 109069074(rab6ba) 109085746 109089355 109112082
CAUA: 113045824 113050623 113054375 113072900 113098965 113109983 113116242
CGIB: 127951398 127960227 127966523 128015557 128020997 128027559
PTET: 122326177(rab6bb) 122331796(rab6a) 122346843(rab6ba) 122347614
LROH: 127166467(rab6ba) 127172515(rab6a) 127179503(rab6bb)
GRF: 141299179(rab6a) 141343826(rab6bb) 141346523(rab6ba)
OMC: 131520815(rab6bb) 131542730(rab6ba) 131548153(rab6a)
PPRM: 120482091(rab6a) 120482875(rab6bb) 120493153(rab6ba)
RKG: 130070966(rab6bb) 130081295(rab6ba) 130105304(rab6a)
MAMB: 125250971(rab6bb) 125261446(rab6a) 125273900(rab6ba)
CIDE: 127496069 127502224 127514688 127520137
CERY: 137002625(rab6bb) 137010798(rab6ba) 137028639(rab6a)
MASI: 127432540 127433532 127441317 127443210 127445733 127449324
TROS: 130546017(rab6a) 130554899(rab6bb)
TDW: 130411868(rab6a) 130418262(rab6bb)
MANU: 129442352(rab6bb) 129446731(rab6a) 129449983(rab6ba)
PDAB: 135718708(rab6ba) 135742682(rab6a) 135766741(rab6bb)
IPU: 100528654(rab6bb) 108271522(rab6ba) 108277061
IFU: 128615199(rab6ba) 128620188(rab6a) 128621644(rab6bb)
PHYP: 113529655(rab6b) 113539331 113544841(rab6a)
SMEO: 124389597(rab6ba) 124393995(rab6a) 124394229(rab6bb)
TFD: 113638410(rab6a) 113643161(rab6ba) 113645226(rab6bb)
TVC: 132844375(rab6ba) 132858201(rab6bb) 132863236(rab6a)
CGAR: 128505457(rab6a) 128527239(rab6ba) 128533520(rab6bb)
NGRA: 132864461(rab6bb) 132873597(rab6a) 132884482(rab6ba)
TRN: 134316776(rab6ba) 134332220(rab6a) 134334226(rab6bb)
AMEX: 103024680(rab6ba) 103024949(rab6a) 103036351(rab6bb)
CMAO: 118804731(rab6bb) 118808038(rab6ba) 118824434(rab6a)
EEE: 113573308(rab6a) 113575924 113588916
CHAR: 105898280(rab6ba) 105899536
SPIL: 134080743(rab6a) 134098291 134102671(rab6ba)
ASAD: 121678398(rab6ba) 121710136(rab6a) 121712368
TRU: 101062416(rab6a) 101077814
TFS: 130537193 130539032(rab6bb)
TNG: GSTEN00022192G001 GSTEN00028397G001
LCO: 104919718 104926030 104929189
NCC: 104957876
TBEN: 117468554 117488344 117491060(rab6ba)
CGOB: 115007150 115018601(rab6a) 115022003
PGEO: 117445759(rab6ba) 117459105(rab6a) 117461835
GACU: 117538477 117558473(rab6bb) 117559033(rab6ba)
EMAC: 134865534(rab6bb) 134869407(rab6ba) 134871855
ELY: 117254110(rab6ba) 117264073 117265271
EFO: 125895309(rab6ba) 125898228(rab6a) 125902465(rab6bb)
PLEP: 121951661(rab6bb) 121952368 121966599(rab6ba)
SLUC: 116046107(rab6bb) 116058820(rab6ba) 116064713(rab6a)
ECRA: 117949882(rab6ba) 117953852 117955308(rab6a)
ESP: 116695685 116698644 116700722(rab6a)
PFLV: 114561335 114565544 114566797(rab6a)
GAT: 120815758 120821922(rab6a) 120823415(rab6ba)
PPUG: 119209665(rab6bb) 119215236(rab6a)
AFB: 129089003 129094430(rab6ba) 129113557
CLUM: 117729708(rab6ba) 117742449 117746627
PSWI: 130190552 130194000(rab6ba) 130197979
CANA: 137782132 137794528(rab6ba) 137803115(rab6a)
CVE: 137865935(rab6bb) 137876609
MSAM: 119895125 119901171(rab6ba) 119902113(rab6bb)
SCHU: 122877532(rab6ba) 122887128(rab6bb) 122888794(rab6a)
EARM: 139287560(rab6ba) 139294799 139296412
CUD: 121512673(rab6ba) 121518675(rab6a) 121520425(rab6bb)
SPUL: 138599074(rab6a) 138607162(rab6ba) 138611843(rab6bb)
LMIX: 132957062(rab6ba) 132979158 132988242
HTC: 141789048(rab6ba) 141792117(rab6a) 141804592(rab6bb)
ALAT: 119010606(rab6bb) 119028899(rab6ba) 119031211(rab6a)
ASTR: 137598843(rab6ba) 137606525 137612340
PKLU: 139202705(rab6ba) 139213487(rab6a) 139214273(rab6bb)
MZE: 101478824 101478866 101482116(rab6a)
ONL: 100696791 100702136(rab6a) 100708038
OAU: 116312974(rab6ba) 116316970(rab6bb) 116330207(rab6a)
OLA: 101156359 101160015(rab6a) 101168856(rab6b)
OML: 112137002(rab6ba) 112142103(rab6a) 112147384(rab6bb)
CSAI: 133451956(rab6bb) 133458064(rab6ba) 133459718
XMA: 102217653 102223209 102226769(rab6a)
XCO: 114147060 114151364 114152810(rab6a)
XHE: 116722101 116725258 116728094(rab6a)
PRET: 103463948 103475734(rab6a) 103479611
PFOR: 103133982(rab6a) 103148318 103151367
PLAI: 106960187 106961408(rab6b) 106964190(rab6a)
PMEI: 106908550 106919080(rab6a) 106933163
GAF: 122838270(rab6ba) 122841035(rab6bb) 122844637
PPRL: 129361670(rab6bb) 129368481 129370486(rab6ba)
CVG: 107083369 107087892(rab6a) 107088682
CTUL: 119786159(rab6bb) 119791033 119795979(rab6ba)
GMU: 124870516(rab6bb) 124873973(rab6ba)
NFU: 107383980 107386547(rab6a) 107396631(rab6b)
KMR: 108239572(rab6bb) 108247591 108249492(rab6ba)
ALIM: 106510862 106527458 106534664
NWH: 119408176(rab6ba) 119415102 119420662(rab6a)
AOCE: 111565032(rab6ba) 111578795(rab6bb) 111579855(rab6a)
EJA: 138196567(rab6a) 138199011(rab6ba) 138202941(rab6bb)
BFRE: 138614260 138622038(rab6a) 138624114(rab6ba)
MCEP: 125009641(rab6ba) 125011287(rab6bb) 125020847
CSEM: 103395316 103396057 103399943(rab6c)
POV: 109625870 109628705 109640261
SSEN: 122771575(rab6bb) 122779423 122780826(rab6ba)
SSOE: 131458263 131462817 131465947(rab6ba)
HHIP: 117760118(rab6ba) 117774001 117778477(rab6bb)
HSP: 118118389(rab6bb) 118121548(rab6ba) 118122053
PPLT: 128448424(rab6ba) 128454834 128457605
SMAU: 118300599(rab6a) 118311617(rab6bb) 118318259(rab6ba)
LCF: 108878935(rab6ba) 108883481 108893683
SDU: 111231995 111234355 111238982
SLAL: 111653970 111654407 111669613
XGL: 120790310(rab6ba) 120799118(rab6bb) 120802373
HCQ: 109512521(rab6a) 109529554 109532396
SSCV: 125970847(rab6ba) 125981719(rab6a) 125985032(rab6bb)
SBIA: 133491672(rab6a) 133503592(rab6ba) 133510806(rab6bb)
PEE: 133406100(rab6ba) 133411524(rab6bb) 133416496
PTAO: 133481392(rab6ba) 133489295(rab6bb)
BPEC: 110154762 110158504 110168141
ENY: 140354059(rab6ba) 140356498(rab6bb) 140360924
MALB: 109957612 109959540(rab6a) 109965725
BSPL: 114844746(rab6bb) 114853623(rab6ba) 114869386
SJO: 128361439(rab6ba) 128368885(rab6bb) 128371247
SSCO: 133984914(rab6ba) 133990585(rab6bb) 133993820(rab6a)
TTY: 137188252(rab6ba) 137194190(rab6bb) 137195407(rab6a)
GMH: 115546667 115548441 115555395
SASA: 100194907(rab6a) 106560618 106568768 106598876(RAB6B) 106603351
STRU: 115149032(rab6a) 115151458 115154493 115156685 115158888 115170023
OTW: 112227116 112240813 112250208 112257712 112260181 121846564
OMY: 110508967 110524898 110530079 110533791 110537329(rab6a) 118964702
OGO: 123991057 123996539 123998854 124009335 124009883 124024841 124042062
ONE: 115103298 115105683 115114166 115124670 115135784
OKI: 109872106 109872606 109875082 109883970 109884447 109892624(rab6a)
OKE: 118390221 118391286(rab6a) 118395180 118402369 127910726(rab6ba) 127931789
OMM: 135508329 135511780(rab6ba) 135524819 135548453(rab6a) 135550560 135558473
OCLA: 139377270 139386944 139409581 139409805 139414735 139418385 139423005
SALP: 111950927 111980669(rab6a)
SNH: 120020309 120045105(rab6a) 120054575 120055490 120057155
SFON: 129814203 129816255(rab6a) 129823796 129867628 129868559 129869467
CCLU: 121534166 121534579 121537624 121573690 121579968 121580717
ELS: 105006227(rab6a) 105028793 105029536(rab6b)
OEP: 134011212(rab6ba) 134035927(rab6bb) 134039269(rab6a)
SFM: 108921248(rab6a) 108921607 108937158
PKI: 111842794(rab6a) 111849404(rab6b)
AANG: 118225565(rab6ba) 118230536 118236181(rab6a)
AROT: 135252541(rab6ba) 135256778 135263183(rab6a)
CCOG: 133126094(rab6ba) 133128468 133132378(rab6a)
LOC: 102689712(rab6a) 102699046(rab6b)
PSPA: 121302945(rab6a) 121323654
ARUT: 117405734 117407118
PSEX: 120523201(rab6a) 120534855(rab6ba)
LCM: 102350398(RAB6B) 102362613(RAB6A)
CMK: 103177151(rab6a) 103189175(rab6ba)
RTP: 109918034(rab6a)
CPLA: 122550851(rab6a)
CPUN: 140481222(rab6a)
HOC: 132816513(rab6a)
SCAU: 119977730(rab6a)
STOZ: 140392003(rab6a)
LERI: 129697879(rab6a)
HAKA: 140726962(rab6a)
PMRN: 116956773 116957857 116958062
LRJ: 133357166(RAB6A)
BFO: 118427347
CIN: 100178081
SCLV: 120328976 120328977
CLEP: 143448706
SPU: 115918044 586726
LPIC: 129279090
LVG: 121430411
AJJ: 139975184
APLC: 110977849
ARUN: 117298931
AAMU: 139945097
AFIL: 140155353
AJC: 117110538
SKO: 100368437
PFLL: 139119308
DME: Dmel_CG6601(Rab6)
DER: 6541847
DSE: 6617716
DSI: Dsimw501_GD27434(Dsim_GD27434)
DYA: Dyak_GE12402
DAN: 6506071
DSR: 110187290
DPO: 4816944
DPE: 113565843
DMN: 108161812
DWI: 6646622
DGR: 6561621
DMO: Dmoj_GI14260
DAZ: 108610467
DNV: 115563489
DHE: 111595016
DVI: 6629208(Rab6)
CCAT: 101452436
BOD: 106620279
BDR: 105232418
RZE: 108359086 108370398
AOQ: 129249479
ALUD: 128864407
TDA: 119687845
MDE: 101892835 101895280
SCAC: 106089326 106093893
LCQ: 111678871 111684493 124419878
LSQ: 119602455 119611027
CVJ: 135950034(Rab6) 135963516
GFS: 119633452 119638877
ECOE: 129940964
CLON: 129606268
HIS: 119654890
AGA: 4577653
ACOZ: 120956027
AARA: 120901282
AMER: 121598994 121601261
ASTE: 118504156
AMAP: 126556322
AFUN: 125768788
AMOU: 128299552
AMRS: 128719245
ANIL: 128730763
AALI: 118464189
ADAR: 125954344
ACOS: 131272679
AAG: 5567448
AALB: 109397409
ASUA: 134225457
CPII: 120415213
CBRI: 134828214
CNS: 116351567
BCOO: 119083294
LLL: 129796227
PPAP: 129802206
AME: 409004
ACER: 108003718
ALAB: 122713461
ADR: 102675351
AFLR: 100870297
BIM: 100742507
BBIF: 117204751
BVK: 117230354
BVAN: 117163796
BHUN: 126865634
BTER: 100648829
BAFF: 126920367
BPYO: 122571115
BPAS: 132906170
FVI: 122536387
CCAL: 108622689
OBB: 114874028
OLG: 117606062
MGEN: 117217612
NMEA: 116429295
CGIG: 122396725
SOC: 105199581
MPHA: 105838210
AEC: 105145422
ACEP: 105621909
MZT: 108726093(Rab6)
CCOA: 108772264
TCZ: 108759418
TSEP: 108749551
PBAR: 105425463
VEM: 105561724
COBS: 139108308(Rab6)
TLN: 139822567(Rab6)
TAME: 143907735(Rab6)
HST: 105189272
DQU: 106745062
CFO: 105255136
FEX: 115242078
PMEC: 138931746(Rab6)
LHU: 105674847(Rab6)
PGC: 109856697
OBO: 105279883
PCF: 106789137
PFUC: 122518145
VPS: 122631010
VCRB: 124425967
VVE: 124951619
NVI: 100121132
CSOL: 105365205
TPRE: 106660067
LHT: 122501568
LBD: 127279819
MDL: 103568158
CGLO: 123262763
CTYP: 141535702(Rab6)
FAS: 105271067
DAM: 107043114
AGIF: 122851395
CINS: 118071888
VCAN: 122416508
CCIN: 107264349
DSM: 124409106
NPT: 124217701(Rab6)
NFB: 124181029
NLO: 107226245
NVG: 124302095
AROA: 105683804
TCA: 661182 663479
TMOL: 138139278 138139591(Rab6)
DPA: 109533865
ESIM: 136409434(Rab6)
EFOR: 136350732(Rab6)
SOY: 115876851
RFG: 143196865(Rab6) 143206928
AGRG: 126748837
ATD: 109600907
CSET: 123321459
HAXR: 123685707
AGB: 108916940
LDC: 111517674
DVV: 126881139
NVL: 108556332
DCOR: 135792824 135797389
APLN: 108743472
PPYR: 116171951
OTU: 111425495
BMOR: 692966
BMAN: 114242886
MSEX: 115441450
BANY: 112050120
MJU: 123871002
NIQ: 126770492
VCD: 124534712
MCIX: 123657985
PMAC: 106716011
PPOT: 106099283
PXU: 106124498
BPHI: 137926785(Rab6)
PRAP: 110995732
PBX: 123714716
PNAP: 125059981
ZCE: 119838761
CCRC: 123697692
LSIN: 126968648
AAGE: 121730563
HAW: 110372928
HZE: 124632475
TNL: 113502231
SLIU: 111353027
OFU: 114360448
ONU: 135074190
ATRA: 106129829
GMW: 113518565
ECLR: 140750254(Rab6)
PXY: 105383900
PGW: 126378890
LGLY: 125225282
CSTB: 134755683
CFUM: 141438114(Rab6)
CFEL: 113377111
CCRN: 123302778
API: 100160399
DNX: 107173580
AGS: 114120669
RMD: 113550365
ACOO: 126839224
DVT: 126902412
BTAB: 109041532
DCI: 103505719
CLEC: 106673238
HHAL: 106683557(Rab6)
NLU: 111062180
LDA: 142324504(Rab6)
HVI: 124363300
MQU: 128988928 128988931
PHU: Phum_PHUM086870
FOC: 113218055
TPAL: 117649052
ZNE: 110826586
CSEC: 111868518
PAME: 138703253
SGRE: 126277900
BROR: 134529543
IEL: 124153734
HAMR: 139687426(Rab6)
FCD: 110844970
DPX: DAPPUDRAFT_128059
DMK: 116927198
DPZ: 124326529
AFRA: 136037017
PVM: 113825121(Rab6)
PJA: 122260161
PCHN: 125025919
PMOO: 119578760
HAME: 121868860
PCLA: 123767154(Rab6)
CQD: 128695678(Rab6)
PTRU: 123512162
ESN: 127008679
MNZ: 135209046
MRJ: 136830249(Rab6)
PORN: 139749832(Rab6)
EAF: 111697817
LSM: 121132331(Rab6)
TCF: 131884258
PPOI: 119109145
ISC: 8037142
DSV: 119442185
DALB: 135917020(Rab6)
RSAN: 119387809
OTI: 135366890
VDE: 111252393
VJA: 111264735
GOE: 100908708
TUT: 107362834
DFR: 124492210
CSCU: 111628093
CVS: 136983224
PTEP: 107455067
ABRU: 129980488
UDV: 129221176
SDM: 118187009
LPOL: 106457335 106462823
PMEO: 129595833
CEL: CELE_F59B2.7(rab-6.1) CELE_T25G12.4(rab-6.2)
CBR: CBG_06854(Cbr-rab-6.1) CBG_15944(Cbr-rab-6.2)
CRQ: GCK72_009281 GCK72_023403
BMY: BM_BM13660(Bma-rab-6.2)
LOA: LOAG_16976
TSP: Tsp_03401
LGI: LOTGIDRAFT_230007
PVUL: 126808671
PCAN: 112554768
LSAX: 138983696
BARL: 143275642
GAE: 121366227 121371209
HRF: 124152126
HRJ: 124277328
HASI: 137281894
HCRA: 139447629
CRG: 105339655
CANU: 128181251
CVN: 111101027
OED: 125657989
MYI: 110465861
PMAX: 117341615
AIRR: 138307623
YBA: 132548873
MCAF: 127738504
MMER: 123555017
DPOL: 127834400
MAEA: 128219688
OBI: 106876560
OSN: 115222264
LJP: 135478980
LAK: 106160287 106172495
SMM: Smp_163580
SHX: MS3_00004684(RAB6B_1)
EGL: EGR_09444
LLON: 135494259
NVE: 5500547
EPA: 110246799
ATEN: 116300301
ADF: 107333800
AMIL: 114953618
AMUA: 136914689
MCAZ: 138028422
MFOO: 137982219
PDAM: 113676280
SPIS: 111330065
DGT: 114524761
XEN: 124446792
HMG: 100197675
HSY: 130636615 130636626
RES: 135684119
TAD: TRIADDRAFT_24643
AQU: 100640480
CCLM: 134196331
ATH: AT2G22290(RABH1d) AT2G44610(RAB6A) AT5G10260(RABH1e)
ALY: 9309516 9314674 9316193
CRB: 17883417 17888289 17890483
CSAT: 104713671 104735036 104751870 104769228 104783013 104784877 104793408 109124478
EUS: EUTSA_v10000663mg EUTSA_v10001633mg EUTSA_v10014689mg
BRP: 103837902 103846822 103855857 103858135 103866149 103866816
BNA: 106365186 106371227 106372483 106384904 106388367 106390112 106414437 106427064 106429302 106438223 106441412 106450783
BOE: 106311368 106318969 106332154 106335713 106337226 106337312
RSZ: 108806430 108810576 108818309 108845856 108846068 108849377 130507163 130511845
THJ: 104798965 104802508 104807693 104808489 104817175 104819297 104827583
CPAP: 110814766 110826438
CIT: 102614860 102616220 102620379
CIC: CICLE_v10022269mg CICLE_v10026499mg CICLE_v10032757mg
PVY: 116135961 116138367
MINC: 123193385 123199499 123216845 123224061
TCC: 18611565 18614552
GRA: 105763527 105763770 105790300 105790595 105802276 105804213
GHI: 107898520 107899766 107911636 107916121 107926324 107934428 107937449 107945394 107945588 107950756 121209922 121224100
GAB: 108467551 108467733 108472581 108478304 108478374 108480030
HSYR: 120126703 120129654 120129836 120136781 120138051 120141857 120170350 120172422 120174404 120189130 120196406 120201479 120206809 120209008 120209150 120217186
DZI: 111288193 111299854 111304526 111313712 111316966
EGR: 104415783 104441327
RARG: 115729171 115738868
GMX: 100527651 100790511 100794537 100794989 100795325 100799871 100809676 100813513
GSJ: 114376367 114382551 114392066 114396437 114412249 114413108 114423130 114423301
PVU: 137808152 137809966 137809968 137812324
VRA: 106765674 106768270 106772506 106777281
VAR: 108324714 108335709 108344799 108347743
VUN: 114170535 114174250 114176363 114176554
VUM: 124821363 124823458 124825361
CCAJ: 109790418 109796910 109800054 109800055 109813502
APRC: 113849034 113851463 113868644 113869137 113872808
MTR: 11427793 11438461 25493558 25501913
TPRA: 123906202 123908914 123909888 123916975 123923934
CAM: 101492440 101496604 101507228 101507522
PSAT: 127074282 127082920 127101318
VVO: 131607809 131632103 131638351 131661452
LJA: 130714052 130714928
ADU: 107469121 107481803 107484285 107487562 107487563
AIP: 107617641 107622520 107631669 107642625 107642626
AHF: 112715173 112734388 112747919 112747920 112784234 112792211 112800403 112800404 112801332
LANG: 109326070 109331924 109332609 109348864 109349595 109359515 109361235
PCIN: 129309116 129310941 129322359
QSA: O6P43_023199 O6P43_024446 O6P43_030466 O6P43_034005
FVE: 101296142 101309388
AANS: 126794475 126802037 126805114
RCN: 112180820 112188858 112196170
PPER: 18774792 18775997 18784751
PMUM: 103328890 103331455 103332983
PAVI: 110747179 110766167 110771800
PDUL: 117613298 117619793 117631224
MDM: 103401672 103417523 103428456 103433340
MSYL: 126584811 126585867 126605863 126627844
PXB: 103930474 103931830 103932608 103934495
PCOX: 137711465 137720965 137734749 137747179
ZJU: 107407898 107421710 107425184
MNT: 21404943
CSAV: 115710763 115714105 115717285
HLP: 133777998 133805364 133807428
CSV: 101204395 101208643
CMO: 103484969 103503500
BHJ: 120073762 120078769
MCHA: 111005589 111026075
CMAX: 111471818 111478505 111491433 111497024
CMOS: 111439590 111453275 111459827 111463174
CPEP: 111782036 111795287 111802393 111804216
RCU: 8263709 8266669 8269065
MEAN: 126654710 126682776
JCU: 105643268 105647908
HBR: 110639366 110643565 110649099 110649279 110657198 110663921
MESC: 110605213 110616288 110627931 110628983
POP: 18096922 7453906 7455205
PEU: 105120706 105121625 105130286 105130973
PALZ: 118031555 118039088 118042283 118062860
PNZ: 133690579 133694142 133702183
JRE: 108989755 109001583 109007102 109008040 109008041
CILL: 122288872 122289852 122294626 122303624 122307739
CAVE: 132166276 132168172 132176111
AGLU: 133855094 133857576 133880101
QSU: 112002300 112012683 112016508 136067613
QLO: 115970965 115995067
CSAA: 142613303 142614943 142614947 142625621
TWL: 119982821 119983585 119995114
VVI: 100242004 100263235 100264362
VRI: 117905455 117917541 117931558
SLY: 101245584 101255401 101262189
SPEN: 107008328 107014400 107018967
SOT: 102585175 102600575 102603643
SSTN: 125859472 125869184 125878300
SDUL: 129880806 129886805 129895438
SVER: 125808456 125821015 125831057
CANN: 107844320 107870988
LBB: 132613809 132637674 132642313 132645852
NTA: 107776647 107779813 107808375 107815510 107818583 107822377 107830228(Nt-rab6)
NSY: 104216019 104217961 104238014 104248043
NTO: 104089090 104089986 104098999 104116559
NAU: 109209711 109225238 109225883 109237345 109238899
INI: 109155936 109172593 109180601 109182420
ITR: 115995723 116012282 116017654 116020691
SIND: 105167357 105171213 105173444 105176459
OEU: 111382026 111389565 111408001 111411604
EGT: 105952447 105954803 105964962 105965429 105973067
SSPL: 121768815 121771151 121773553 121773785 121776276 121776389 121785122 121787563 121791120
SMIL: 131001434 131015833 131021828 131022135
SHIS: 125216010 125218788 125220623
APAN: 127242331 127252314 127263394
HPUM: 140881129 140887463 140892038
PHUA: 140963406 140970672 140971001 140972810
PEBU: 140821895 140826304 140826660 140838428
PTAB: 142505565 142546507 142546834 142551962 142552165
CARB: 113700215 113702495 113726914 113732054
HAN: 110864526 110873563 110878327 110885921 110910911
BHW: 143529523 143538136 143555405 143555780 143564339 143570276 143579580 143599851 143602109 143602438 143606040 143606755 143620541 143623443
ECAD: 122578075 122587192 122603837
LSV: 111897308 111898396 111907364 111911754 111918893 111921409
CCAV: 112504669 112515233 112515358 112519238 112527436
DCR: 108193563 108213396 108215868 108217367
AGRV: 141692886 141721403 141724259
CSIN: 114303341 114311331 114314490
RVL: 131298210 131331960
AEW: 130776977 130781567 130781796 130781983 130785393 130792494
DLT: 127787455 127800820 127800969 127804156
BVG: 104892894 104895675
SOE: 110781624 110791050
CQI: 110682212 110717811 110730248 110732466
ATRI: 130799571 130801520 130807405
SLAF: 141592929 141623245 141634012 141639406 141653703
MOF: 131159546 131164970 131166176
NNU: 104605056 104605980 104606418
MING: 122057403 122073335 122082357 122088639
TSS: 122643975 122652308 122666209 122669605
PSOM: 113286860 113297338 113302098 113336088
OSA: 4343293
DOSA: Os07g0496000
OBR: 102716144
OGL: 127780082
BDI: 100823113
ATS: 109773288
TDC: 119354624 119363662
TAES: 123044901 123052614 123188582
TUA: 125528134
HVG: 123426007
LPER: 127333759
LRD: 124674461 124674809
SBI: 8061565 8080712
ZMA: 100274535 100283901 103647867
MFLO: 136546799 136552383
SITA: 101755482 101786265
SVS: 117843605 117844904
PVIR: 120661407 120661884 120688586 120694538
PHAI: 112882421
PAUA: 133890922 133891417 133892788 133893001 133914027
TANG: 140762871 140765838 140774378 140779672
PDA: 103701756 103703574 103711253 103722564 113462560
EGU: 105041616 105043817 105048624 105053896 105059559
MUS: 103973167 103976961 103987460 135606270 135612373
ZOF: 121989080 121992439 121996383 121998037 122021316 122024356 122041464 122045965 122052260 122056747
DCT: 110097984 110108560
PEQ: 110021610 110030343
AOF: 109819636 109850524
MSIN: 131233449 131242274 131248122
ACAK: 137934506 137936598 137941109
NCOL: 116253099 116266214
ATR: 18429094 18442855
CJF: 131032431
SMO: SELMODRAFT_145680(Rab6-1) SELMODRAFT_271169(Rab6-2)
PPP: 112274319 112275356 112278903 112280166 112284225 112288301 112293725
CRE: CHLRE_01g047550v5
VCN: VOLCADRAFT_73845(rabH)
CSL: COCSUDRAFT_37676
CVR: CHLNCDRAFT_36840
APRO: F751_5440
MIS: MICPUN_56018(RAB)
MPP: MICPUCDRAFT_33050
SRE: PTSG_11445
 » show all
Reference
1  [PMID:1898771]
  Authors
Bourne HR, Sanders DA, McCormick F.
  Title
The GTPase superfamily: conserved structure and molecular mechanism.
  Journal
Nature 349:117-27 (1991)
DOI:10.1038/349117a0
Reference
2  [PMID:7888179]
  Authors
Hall A.
  Title
Small GTP-binding proteins and the regulation of the actin cytoskeleton.
  Journal
Annu Rev Cell Biol 10:31-54 (1994)
DOI:10.1146/annurev.cb.10.110194.000335
Reference
3  [PMID:9434896]
  Authors
Geyer M, Wittinghofer A.
  Title
GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins.
  Journal
Curr Opin Struct Biol 7:786-92 (1997)
DOI:10.1016/S0959-440X(97)80147-9
Reference
4  [PMID:9446556]
  Authors
Vitale N, Moss J, Vaughan M.
  Title
Molecular characterization of the GTPase-activating domain of ADP-ribosylation factor domain protein 1 (ARD1).
  Journal
J Biol Chem 273:2553-60 (1998)
DOI:10.1074/jbc.273.5.2553
Other DBs
ExplorEnz - The Enzyme Database: 3.6.5.2
IUBMB Enzyme Nomenclature: 3.6.5.2
ExPASy - ENZYME nomenclature database: 3.6.5.2
BRENDA, the Enzyme Database: 3.6.5.2

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Protein sequence (72186)   
   UniProt (69261)   
   SWISS-PROT (526)   
   RefSeq(pep) (1290)   
   PDBSTR (1109)   
DNA sequence (1695)   
   RefSeq(nuc) (1353)   
   GenBank (185)   
   EMBL (157)   
3D Structure (416)   
   PDB (416)   
Protein domain (22)   
   InterPro (22)   
All databases (74319)   

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