KEGG   ENZYME: 3.7.1.5Help
Entry
EC 3.7.1.5                  Enzyme                                 

Name
acylpyruvate hydrolase
Class
Hydrolases;
Acting on carbon-carbon bonds;
In ketonic substances
BRITE hierarchy
Sysname
3-acylpyruvate acylhydrolase
Reaction(IUBMB)
a 3-acylpyruvate + H2O = a carboxylate + pyruvate [RN:R00543]
Reaction(KEGG)
Substrate
3-acylpyruvate [CPD:C02119];
H2O [CPD:C00001]
Product
carboxylate [CPD:C00060];
pyruvate [CPD:C00022]
Comment
Acts on formylpyruvate, 2,4-dioxopentanoate, 2,4-dioxohexanoate and 2,4-dioxoheptanoate.
History
EC 3.7.1.5 created 1976
Pathway
ec00350  Tyrosine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01557  acylpyruvate hydrolase
K16164  acylpyruvate hydrolase
Genes
HSA: 81889(FAHD1)
PTR: 741017
PPS: 100975679(FAHD1)
GGO: 101125430(FAHD1)
PON: 100171851(FAHD1)
NLE: 100587967(FAHD1)
MCC: 722505(FAHD1)
MCF: 102130069(FAHD1)
CSAB: 103226357(FAHD1)
RRO: 104681522(FAHD1)
RBB: 108525090(FAHD1)
CJC: 100415399(FAHD1)
SBQ: 101050974(FAHD1)
MMU: 68636(Fahd1)
RNO: 302980(Fahd1)
CGE: 100766004(Fahd1)
NGI: 103752437(Fahd1)
HGL: 101726287(Fahd1)
CCAN: 109690203(Fahd1)
OCU: 103346763(FAHD1)
TUP: 102484426(FAHD1) 102496819
CFA: 490068(FAHD1)
AML: 100478980(FAHD1)
UMR: 103668480(FAHD1) 103673185
ORO: 101366879(FAHD1)
FCA: 101084249(FAHD1)
PTG: 102954443(FAHD1)
AJU: 106982786(FAHD1)
BTA: 509273(FAHD1)
BOM: 102283520(FAHD1)
BIU: 109578709(FAHD1) 109578747
PHD: 102322126(FAHD1)
CHX: 102191198(FAHD1)
OAS: 101113379(FAHD1)
SSC: 110256733(FAHD1)
CFR: 102521346(FAHD1)
CDK: 105099732(FAHD1) 105102070
BACU: 103002308(FAHD1)
LVE: 103068702(FAHD1)
OOR: 101280572(FAHD1)
ECB: 100067938(FAHD1)
EPZ: 103540032(FAHD1)
EAI: 106836217(FAHD1)
MYB: 102257710(FAHD1)
MYD: 102761206(FAHD1)
HAI: 109385956(FAHD1)
RSS: 109435314(FAHD1) 109443110
PALE: 102884243(FAHD1)
LAV: 100672838(FAHD1)
TMU: 101355175
MDO: 107649632(FAHD1)
SHR: 100916356(FAHD1)
GGA: 416538(FAHD1)
MGP: 100548869(FAHD1)
CJO: 107320643(FAHD1)
APLA: 101794881(FAHD1)
ACYG: 106032133(FAHD1)
TGU: 100228951(FAHD1)
GFR: 102044583(FAHD1)
FAB: 101805992(FAHD1)
PHI: 102109601(FAHD1)
PMAJ: 107211416(FAHD1)
CCW: 104685003(FAHD1)
FPG: 101923324(FAHD1)
FCH: 102059711(FAHD1)
CLV: 102093257(FAHD1)
EGZ: 104127717(FAHD1)
AAM: 106493837(FAHD1)
ASN: 102388761(FAHD1)
AMJ: 102563376(FAHD1)
PSS: 102451035(FAHD1)
CMY: 102939645(FAHD1)
CPIC: 101939243(FAHD1)
ACS: 100566181(fahd1)
PVT: 110085599(FAHD1)
PBI: 103060707(FAHD1)
GJA: 107115608(FAHD1)
XLA: 108701672(fahd1.L)
XTR: 100486946(fahd1)
NPR: 108790870(FAHD1)
DRE: 553762(fahd1)
SRX: 107728885(fahd1)
IPU: 108254991(fahd1)
AMEX: 103027176
TRU: 101069361(fahd1)
LCO: 104918826(fahd1)
NCC: 104964785(fahd1)
MZE: 101471590(fahd1)
OLA: 101162761(fahd1)
XMA: 102235075(fahd1)
PRET: 103469240(fahd1)
NFU: 107376542(fahd1)
CSEM: 103393076 103393080(fahd1)
LCF: 108879772(fahd1)
HCQ: 109522729(fahd1)
BPEC: 110169161(fahd1)
ELS: 105013016(fahd1)
SFM: 108935710(fahd1)
LCM: 102365680(FAHD1)
SPU: 581398
APLC: 110979736
DME: Dmel_CG5793(CG5793)
DSI: Dsimw501_GD19399(Dsim_GD19399)
MDE: 101901278
AAG: 5578010
TCA: 664303
DPA: 109546950
NVL: 108565281
ZNE: 110829664
TUT: 107368805
CEL: CELE_ZK688.3(fahd-1)
CBR: CBG12264
BMY: Bm1_36665
TSP: Tsp_01354
MYI: 110455396
OBI: 106873771
LAK: 106164766
SHX: MS3_09272
EPA: 110242141
ADF: 107333226
AQU: 100634473
THJ: 104802581
CPAP: 110815029
CIT: 102606702
TCC: 18603537
GRA: 105775205
GHI: 107936139
VRA: 106768193
VAR: 108343559
CCAJ: 109809918
CAM: 101491289
LJA: Lj4g3v2309270.1(Lj4g3v2309270.1)
ADU: 107463369
AIP: 107638759
LANG: 109362883
FVE: 101291042
PPER: 18791153
PMUM: 103323041
PAVI: 110750288
MDM: 103403735
PXB: 103945978
ZJU: 107433161
CSV: 101207065
CMO: 103483862
MCHA: 111009147
CMAX: 111479470
CMOS: 111457421
CPEP: 111789913
RCU: 8278756
JCU: 105643457
HBR: 110633057
POP: 7496679
VVI: 100251672
SLY: 101258990
SPEN: 107009288
SOT: 102590064
CANN: 107879874
NSY: 104210296
NTO: 104113653
SIND: 105156881
OEU: 111371490
HAN: 110865077
LSV: 111917254
NNU: 104598901
DOSA: Os03t0421700-00(Os03g0421700) Os03t0829000-01(Os03g0829000)
OBR: 102717889
ATS: 109762923(LOC109762923) 109786576(LOC109786576)
ZMA: 100272625(TIDP3450) 100283765(pco067797)
SITA: 101764301
PDA: 103721684
EGU: 105052542
MUS: 103978953
DCT: 110104426
PPP: 112287135
CNE: CNJ01210
CNB: CNBJ2250
ABP: AGABI1DRAFT111004(AGABI1DRAFT_111004)
ABV: AGABI2DRAFT190205(AGABI2DRAFT_190205)
MGL: MGL_2178
DDI: DDB_G0275071(fahd1)
SPAR: SPRG_04935
BHA: BH2000
BTW: BF38_4195
BAG: Bcoa_1587
CGL: NCgl2919(Cgl3022)
CGB: cg3350(hpaG)
CGU: WA5_2919(NagK)
CGT: cgR_2909
CGM: cgp_3350(nagK)
CGJ: AR0_14635
CEF: CE2859
CJK: jk0312
CUR: cu1672
CAR: cauri_0890(hpaF)
CPU: cpfrc_00153(faa)
CPL: Cp3995_0153(hpaF)
CPG: Cp316_0165(hpaF)
CPP: CpP54B96_0156(hpaF)
CPK: Cp1002_0151(hpaF)
CPQ: CpC231_0154(hpaF)
CPX: CpI19_0153(hpaF)
CPZ: CpPAT10_0153(hpaF)
COR: Cp267_0160(hpaF)
COP: Cp31_0167(hpaF)
COD: Cp106_0153(hpaF)
COS: Cp4202_0149(hpaF)
COI: CpCIP5297_0162(hpaF)
COE: Cp258_0163(hpaF)
COU: Cp162_0157(hpaF)
CPSE: CPTA_00681
CPSU: CPTB_00852
CPSF: CPTC_00514
CRD: CRES_0218
CUL: CULC22_00199(faa)
CUC: CULC809_00202(faa)
CUN: Cul210932_0215(hpaF)
CUS: CulFRC11_0202(hpaF)
CUQ: Cul210931_0208(hpaF)
CUZ: Cul05146_0222(hpaF)
CUJ: CUL131002_0201(hpaF)
CVA: CVAR_0513
CSX: CSING_04890(hpaF)
CTED: CTEST_04140(faa)
CUT: CUTER_03705(faa)
CSP: WM42_0483
NFA: NFA_12410
ROP: ROP_15430
SHY: SHJG_0193
MTS: MTES_3607
ART: Arth_2051
AAU: AAur_0330
XCE: Xcel_0305
CFL: Cfla_0281
FAL: FRAAL6170
CAI: Caci_6464
CWO: Cwoe_2814
 » show all
Taxonomy
Reference
1  [PMID:4375963]
  Authors
Watson GK, Houghton C, Cain RB.
  Title
Microbial metabolism of the pyridine ring. The metabolism of pyridine-3,4-diol (3,4-dihydroxypyridine) by Agrobacterium sp.
  Journal
Biochem J 140:277-92 (1974)
Other DBs
ExplorEnz - The Enzyme Database: 3.7.1.5
IUBMB Enzyme Nomenclature: 3.7.1.5
ExPASy - ENZYME nomenclature database: 3.7.1.5
UM-BBD (Biocatalysis/Biodegradation Database): 3.7.1.5
BRENDA, the Enzyme Database: 3.7.1.5
CAS: 54004-67-0

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