| Entry |
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| Name |
haloacetate dehalogenase;
monohaloacetate dehalogenase
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| Class |
Hydrolases;
Acting on halide bonds;
In carbon-halide compounds
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| Sysname |
haloacetate halidohydrolase
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| Reaction(IUBMB) |
haloacetate + H2O = glycolate + halide [RN: R02336]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 3.8.1.3 created 1972
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| Pathway |
| ec00361 | Chlorocyclohexane and chlorobenzene degradation |
| ec00625 | Chloroalkane and chloroalkene degradation |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K01561 | haloacetate dehalogenase |
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| Genes |
| CLAP: | NCTC11466_02285(dehH1) |
| SOF: | NCTC11214_04587(dehH1) |
| EAME: | GXP68_14140 GXP68_23300 |
| PVA: | Pvag_pPag20079 Pvag_pPag30364 |
| LRI: | NCTC12151_03420(dehH1) |
| PLUL: | FOB45_04980 FOB45_24525 |
| PPSL: | BJP27_13710 BJP27_18085 |
| PVW: | HU752_011670 HU752_014200 |
| NAX: | HC341_07505 HC341_09105 |
| GAI: | IMCC3135_09085(dehH1) |
| HALO: | BWR19_00460 BWR19_14970 |
| RSM: | CMR15_30691(dehH) CMR15_mp10103(dehH) |
| RPJ: | N234_00775 N234_01185 |
| REH: | H16_A0197(h16_A0197) |
| RME: | Rmet_0129(dehH2) Rmet_0202(dehH1) |
| CBW: | RR42_m0210 RR42_m0311 |
| CCUP: | BKK81_03345 BKK81_03800 |
| CUP: | BKK80_02690 BKK80_03145 |
| CUU: | BKK79_09120 BKK79_09580 |
| COX: | E0W60_11575 E0W60_11925 |
| BPM: | BURPS1710b_0537(dehH) |
| BVI: | Bcep1808_3053 Bcep1808_4587 |
| BCH: | Bcen2424_2964 Bcen2424_6337 |
| BCM: | Bcenmc03_2985 Bcenmc03_7003 |
| BCJ: | BCAL0627 BCAL2528 BCAL2541 BCAS0570 |
| BAC: | BamMC406_1083 BamMC406_2875 |
| BCED: | DM42_2098 DM42_7259 |
| BCEP: | APZ15_02725 APZ15_36080 |
| BDL: | AK34_143 AK34_3500 AK34_5202 |
| BPYR: | ABD05_04860 ABD05_32215 |
| BDF: | WI26_14300 WI26_30480 |
| BGF: | BC1003_0183 BC1003_0718 BC1003_1416 BC1003_3822 |
| BGD: | bgla_1g36550 bgla_2g17110 bgla_2g19360 |
| BGO: | BM43_1166 BM43_5399 BM43_5665 |
| BYI: | BYI23_A000720 BYI23_C005070 |
| BUE: | BRPE67_ACDS00790 BRPE67_CCDS06460 |
| BUQ: | AC233_01055 AC233_03090 |
| BGP: | BGL_1c34420 BGL_2c17150 BGL_2c20880 |
| BPLA: | bpln_1g33380 bpln_2g17840 bpln_2g20990 |
| BUM: | AXG89_06535 AXG89_19240 AXG89_35025 |
| BUI: | AX768_17480 AX768_29005 |
| BURK: | DM992_05025 DM992_38450 |
| BPX: | BUPH_04069 BUPH_05503 |
| BPY: | Bphyt_0433 Bphyt_2732 |
| BUZ: | AYM40_00890 AYM40_22975 AYM40_28335 AYM40_29375 |
| BCAI: | K788_0004166 K788_0006206 K788_0008295 |
| PARA: | BTO02_01920 BTO02_04335 BTO02_26125 |
| PARB: | CJU94_04355 CJU94_31465 |
| PHS: | C2L64_01050 C2L64_37280 C2L64_40840 C2L64_40995 C2L64_45670 |
| PTER: | C2L65_00880 C2L65_33385 C2L65_37730 C2L65_37885 |
| PGP: | CUJ91_01175 CUJ91_03210 |
| PCJ: | CUJ87_00935 CUJ87_03610 |
| PTS: | CUJ90_01065 CUJ90_26400 |
| PCAF: | DSC91_004097 DSC91_005605 |
| PMEG: | FNZ07_04460 FNZ07_14830 |
| PACP: | FAZ97_00885 FAZ97_32935 FAZ97_34195 |
| PACS: | FAZ98_00820 FAZ98_29335 |
| PEW: | KZJ38_00145 KZJ38_19345 KZJ38_28785 |
| CABA: | SBC2_01640 SBC2_70470(dehH1) |
| AXX: | ERS451415_05979(dehH1) |
| RHY: | RD110_23365 RD110_23610 |
| POS: | DT070_08410 DT070_14750 |
| POO: | F7R28_01005 F7R28_15855 |
| PVAC: | HC248_00263 HC248_01382 |
| ACK: | C380_14840 C380_22215 |
| LIH: | L63ED372_00065 L63ED372_02923(dehH1) |
| PBH: | AAW51_0642(dehH) AAW51_2052(dehH) |
| GLC: | JQN73_08195 JQN73_08790 |
| RGU: | A4W93_17060 A4W93_22330 |
| UPL: | DSM104440_02964(dehH1) |
| MAM: | Mesau_02577 Mesau_03242 |
| MESM: | EJ066_00545 EJ066_05480 |
| REC: | RHECIAT_PC0000461 RHECIAT_PC0000825 |
| RLT: | Rleg2_0115 Rleg2_5248 |
| RHL: | LPU83_pLPU83c0450(deh) LPU83_pLPU83d1033 LPU83_pLPU83d1210 |
| RLS: | HB780_10255 HB780_13175 |
| NGL: | RG1141_PA10740 RG1141_PA12050 |
| NEN: | NCHU2750_42780(dehH) |
| BJA: | bll7497(bll7497) blr6965(blr6965) |
| BJU: | BJ6T_17920 BJ6T_63890 |
| BJP: | RN69_08840 RN69_30960 |
| BOT: | CIT37_06735 CIT37_17710 |
| BGQ: | X265_04105 X265_31780 |
| BARH: | WN72_14040 WN72_42645 |
| BVZ: | BRAD3257_1144 BRAD3257_4896 |
| BEL: | BE61_16190 BE61_83120 |
| BQB: | J4P68_0012000 J4P68_0027870 |
| RPX: | Rpdx1_0929 Rpdx1_1333 |
| VGO: | GJW-30_1_00409 GJW-30_1_01091 |
| BOP: | AXW83_00200 AXW83_00855 |
| BOS: | BSY19_1502 BSY19_1640 |
| BVV: | BHK69_10800 BHK69_11525 BHK69_15055 |
| BOI: | BLM15_14380 BLM15_15025 BLM15_29815 |
| BOF: | FQV39_05315 FQV39_11910 FQV39_12470 |
| STAR: | G3545_11160 G3545_19300 G3545_20450 |
| MAQU: | Maq22A_c19895(mhpC) |
| METD: | C0214_20770 C0214_21175 |
| METS: | DK389_23395 DK389_29920 |
| METI: | DK427_12855 DK427_13800 |
| MTEA: | DK419_16200 DK419_23295 |
| MOC: | BB934_06630 BB934_17955 |
| RHZ: | RHPLAN_15270 RHPLAN_17720 RHPLAN_64820 |
| AALA: | IGS74_00145 IGS74_16390 |
| AALM: | LUX29_00140 LUX29_13270 LUX29_18480 |
| PSIN: | CAK95_01725 CAK95_13355 |
| PHR: | C6569_00165 C6569_15345 |
| PSTG: | E8M01_04505 E8M01_14735 E8M01_15205 E8M01_16940 |
| RLI: | RLO149_c016110(dehH) |
| RPON: | G3256_09775 G3256_16245 |
| SULZ: | C1J03_11050 C1J03_13380 |
| SPSE: | SULPSESMR1_01227(dehH1) |
| RID: | RIdsm_00967 RIdsm_03190(dehH1) |
| KEU: | S101446_03085 S101446_03438 |
| AOZ: | HUE56_06380 HUE56_09660 |
| NAO: | Y958_12725 Y958_15715 Y958_15875 |
| SKT: | IGS68_07130 IGS68_07280 |
| SMUC: | JL100_020340 JL100_020460 |
| SROE: | JL101_019085 JL101_019230 |
| PFAC: | PFJ30894_01307(dehH1) |
| MGO: | AFA91_05575 AFA91_20315 |
| MSM: | MSMEG_1984 MSMEG_6708 |
| MSG: | MSMEI_1940 MSMEI_6526 |
| MSB: | LJ00_09900 LJ00_33145 |
| MSN: | LI99_09900 LI99_33150 |
| MSH: | LI98_09900 LI98_33155 |
| NBR: | O3I_003895 O3I_026365 |
| NOZ: | DMB37_01465 DMB37_24875 |
| NAH: | F5544_13160 F5544_19485 F5544_29745 F5544_39915 |
| NIE: | KV110_04230 KV110_07610 KV110_16005 KV110_21600 |
| NYA: | LTV02_07675 LTV02_15310 |
| NGP: | LTT66_12725 LTT66_31215 |
| RBY: | CEJ39_01820 CEJ39_14295 |
| RHQ: | IM25_05280 IM25_17510 |
| RRT: | 4535765_02533(fac-dex) |
| RKO: | JWS14_18825 JWS14_19110 |
| SCO: | SCO0899(SCM1.32) SCO7205(SC2H12.04) |
| SSX: | SACTE_0567 SACTE_5620 |
| SHY: | SHJG_1163 SHJG_1793 SHJG_7349 |
| SHO: | SHJGH_0998 SHJGH_1558 SHJGH_7109 |
| SRC: | M271_21155 M271_34810 |
| SMAL: | SMALA_2230 SMALA_4508 |
| SSOI: | I1A49_14285 I1A49_26615 |
| SCT: | SCAT_5235 SCAT_p1160 |
| SCY: | SCATT_52280 SCATT_p05710 |
| SBH: | SBI_01204 SBI_03287 SBI_04223 |
| SCI: | B446_01195 B446_32805 B446_34100 |
| SLV: | SLIV_03270 SLIV_33425 |
| SCX: | AS200_02280 AS200_41655 |
| SRW: | TUE45_pSRc_0178(TUE45_pSRTUE45c_0178) |
| SLE: | sle_06290(sle_06290) |
| SPAV: | Spa2297_02820 Spa2297_29120 |
| SAUO: | BV401_14590 BV401_26395 |
| SSIA: | A7J05_33300 A7J05_34325 |
| SQZ: | FQU76_00110 FQU76_33630 |
| SBY: | H7H31_10950 H7H31_13915 |
| SRIM: | CP984_04910 CP984_35080 |
| SHUN: | DWB77_00873(fac-dex) |
| SACT: | DMT42_00680 DMT42_01870 |
| SDEC: | L3078_00530 L3078_03510 L3078_06985 |
| STRI: | C7M71_002460 C7M71_023970 |
| NANO: | G5V58_10060 G5V58_16755 |
| NAQU: | ENKNEFLB_04424(fac-dex) |
| KFL: | Kfla_0903 Kfla_5120 Kfla_6391 |
| NDA: | Ndas_0829 Ndas_1021 Ndas_2139 |
| NAL: | B005_4630 B005_5069 B005_5109 |
| ACTW: | F7P10_01915 F7P10_23695 |
| AGRA: | AGRA3207_001474 AGRA3207_002763 AGRA3207_005272 AGRA3207_007752 |
| NOA: | BKM31_16395 BKM31_31060 BKM31_37720 BKM31_39830 |
| NCX: | Nocox_12255 Nocox_23245 |
| NGN: | LCN96_07210 LCN96_14165 |
| FRI: | FraEuI1c_4110 FraEuI1c_6548 |
| AJA: | AJAP_14685 AJAP_41505 |
| AMQ: | AMETH_0379 AMETH_3823 |
| AMYC: | CU254_00780 CU254_03310 CU254_25540 |
| AMYB: | BKN51_17290 BKN51_33205 |
| AAB: | A4R43_01365 A4R43_02695 A4R43_15285 A4R43_16735 |
| AMYY: | YIM_13715 YIM_15225 YIM_28310 YIM_29195 |
| AORI: | SD37_00825 SD37_24470 |
| AACD: | LWP59_01780 LWP59_04245 |
| PSEA: | WY02_19730 WY02_22685 WY02_25280 |
| PSEQ: | AD006_02365 AD006_27430 |
| PECQ: | AD017_07025 AD017_10180 |
| PHH: | AFB00_10155 AFB00_18415 |
| PAUT: | Pdca_03760 Pdca_14770 Pdca_47580 |
| SESP: | BN6_27730 BN6_48220 |
| KPHY: | AOZ06_18530 AOZ06_39255 AOZ06_46360 |
| LED: | BBK82_33445 BBK82_45155 |
| MAU: | Micau_2861 Micau_3067 |
| MICB: | MicB006_2129 MicB006_5973 |
| MTUA: | CSH63_09770 CSH63_10775 |
| MTEM: | GCE86_03690 GCE86_06525 GCE86_30915 |
| AIH: | Aiant_12900 Aiant_81330 |
| PFLA: | Pflav_040790 Pflav_040840 |
| PSUU: | Psuf_068380 Psuf_074830 |
| DVC: | Dvina_30365 Dvina_31595 Dvina_45385 |
| CCAZ: | COUCH_18025 COUCH_23230 |
| GLY: | K3N28_01895 K3N28_12020 |
| RUB: | GBA63_12215 GBA63_17385 |
| KBS: | EPA93_10860 EPA93_27755 |
| SCAS: | SACC_10520 SACC_13870 |
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| Reference |
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| Authors |
GOLDMAN P. |
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| Title |
THE ENZYMATIC CLEAVAGE OF THE CARBON-FLUORINE BOND IN FLUOROACETATE. |
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| Journal |
J Biol Chem 240:3434-8 (1965) |
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| Reference |
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| Authors |
Goldman P, Milne GW. |
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| Title |
Carbon-fluorine bond cleavage. II. Studies on the mechanism of the defluorination of fluoroacetate. |
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| Journal |
J Biol Chem 241:5557-9 (1966) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.8.1.3 |
| ExPASy - ENZYME nomenclature database: | 3.8.1.3 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 3.8.1.3 |
| BRENDA, the Enzyme Database: | 3.8.1.3 |
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