KEGG   ENZYME: 4.1.1.120
Entry
EC 4.1.1.120                Enzyme                                 

Name
3-oxoisoapionate decarboxylase;
oiaC (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-oxoisoapionate carboxy-lyase
Reaction(IUBMB)
3-oxoisoapionate = L-erythrulose + CO2 [RN:R12609]
Reaction(KEGG)
R12609
Substrate
3-oxoisoapionate [CPD:C22220]
Product
L-erythrulose [CPD:C02045];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from several bacterial species, is involved in the degradation of D-apionate. Stereospecificity of 3-oxoisoapionate has not been determined.
History
EC 4.1.1.120 created 2020
Orthology
K23248  3-oxoisoapionate decarboxylase
Genes
EFE: EFER_0432
SYM: K6K13_04235
AHN: NCTC12129_01616
IZH: FEM41_02310
RBAD: H2866_02225
ECA: ECA0868
PATR: EV46_03990
PATO: GZ59_08040
PCC: PCC21_007730
PCV: BCS7_03825
EBI: EbC_33090
CJQ: UC78_1026
CCQ: N149_1009
CCY: YSS_05790
CCOI: YSU_03680
CCOF: VC76_05235
DALK: DSCA_45440
SME: SMc00267
SMER: DU99_09260
KAI: K32_00200
PSWU: SY83_22160
CTC: CTC_01174
ELM: ELI_0071
AIN: Acin_2021
SCO: SCO0577(SC5G5.09c)
SMAL: SMALA_4775
SFA: Sfla_3626
SBH: SBI_04327
STRP: F750_3091
STRD: NI25_01440
MTS: MTES_2013
PDX: Psed_3726
AMI: Amir_2650
ACTI: UA75_20485
ACAD: UA74_19985
TTF: THTE_0223
AGV: OJF2_37210 OJF2_65550(iolE_6)
ABAS: ACPOL_4619
SUS: Acid_5326
SLI: Slin_3986
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
[eca:ECA0868]
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.120
IUBMB Enzyme Nomenclature: 4.1.1.120
ExPASy - ENZYME nomenclature database: 4.1.1.120
BRENDA, the Enzyme Database: 4.1.1.120

DBGET integrated database retrieval system