KEGG   ENZYME: 4.1.1.120
Entry
EC 4.1.1.120                Enzyme                                 
Name
3-oxoisoapionate decarboxylase;
oiaC (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-oxoisoapionate carboxy-lyase
Reaction(IUBMB)
3-oxoisoapionate = L-erythrulose + CO2 [RN:R12609]
Reaction(KEGG)
R12609
Substrate
3-oxoisoapionate [CPD:C22220]
Product
L-erythrulose [CPD:C02045];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from several bacterial species, is involved in the degradation of D-apionate. Stereospecificity of 3-oxoisoapionate has not been determined.
History
EC 4.1.1.120 created 2020
Orthology
K23248  3-oxoisoapionate decarboxylase
Genes
EFE: EFER_0432
SYM: K6K13_04235
AHN: NCTC12129_01616
ASUB: NLZ15_15035
IZH: FEM41_02310
RBAD: H2866_02225
RCB: O1V66_01100
ECA: ECA0868
PATR: EV46_03990
PATO: GZ59_08040
PCC: PCC21_007730
PCV: BCS7_03825
PAQU: DMB82_0016430
PVZ: OA04_08710
PQU: IG609_016195
EBI: EbC_33090
EPE: CI789_01895
ERP: LJN55_16950
PAO: Pat9b_4285
KLN: LH22_13020
LRI: NCTC12151_01556
HAA: A5892_08230
KMA: B9H00_09315
RHY: RD110_21140
MOP: Mesop_6008
MERD: EB233_28515
HOE: IMCC20628_00969
AAK: AA2016_0619
AMIH: CO731_00630 CO731_01229
SME: SMc00267
SMQ: SinmeB_1444
SMX: SM11_chr1710
SMEG: C770_GR4Chr1737
SMEL: SM2011_c00267
SMER: DU99_09260
RJG: CCGE525_37070
KAI: K32_00200
DEQ: XM25_04100 XM25_21995
DEI: C4375_05010
YTI: FNA67_07940
OAR: OA238_c42350
CMAR: IMCC12053_2351
TPRO: Ga0080559_TMP325
PLIA: E4191_04010
PMAU: CP157_03553
PSEW: JHW44_20060
RBZ: B9057_14905
THW: BMG03_00050
TEC: AKL02_018005
CJQ: UC78_1026
CCOL: BN865_10620
CCC: G157_03600
CCQ: N149_1009
CCY: YSS_05790
CCOI: YSU_03680
CCOF: VC76_05235
CCOO: ATE51_01468
CNV: CNZW441b_1052
DWD: DSCW_06630
DALK: DSCA_45440
BSJ: UP17_01700 UP17_10095
MDG: K8L98_23360
BLEN: NCTC4824_01118
BCHS: JNE38_14960
BPAB: PSE45_04215
PJD: Pjdr2_3667 Pjdr2_5267
POD: PODO_15160
PBJ: VN24_09315
PSON: JI735_07970
POW: IJ21_41540
PBV: AR543_07325
PYG: AWM70_00525
PSWU: SY83_22160
PLEN: EIM92_02525
PPSC: EHS13_08905
PLUT: EI981_02610
PALB: EJC50_17895 EJC50_24835
PBAC: HUB98_18300
PRZ: GZH47_06375 GZH47_24960
PLYC: GXP70_09875 GXP70_27320
COHN: KCTCHS21_47780
AFX: JZ786_23525
VIJ: JNUCC6_00980
CTC: CTC_01174
CFER: D4Z93_03625
CRS: FQB35_12465 FQB35_12470
CAPR: EQM14_09335
ACOL: K5I23_08685
ARF: AR1Y2_3059
ACHT: bsdcttw_16330
WHJ: H9Q79_14475
FWA: DCMF_02110
ELM: ELI_0071
EMT: CPZ25_013570
ELIM: B2M23_03470
VPY: HZI73_21515
AIN: Acin_2021
MDX: BTO20_34455
ROA: Pd630_LPD02145 Pd630_LPD07140
SCO: SCO0577(SC5G5.09c)
SMAL: SMALA_4775
SSOI: I1A49_27985
SFA: Sfla_3626
SBH: SBI_04327
STRP: F750_3091
SLV: SLIV_35060
SXI: SXIM_40210
SCZ: ABE83_02050
SGM: GCM10017557_02950
STRD: NI25_01440
SAUO: BV401_27735
SGD: ELQ87_37480
SPAD: DVK44_35085
SFUG: CNQ36_25910
SHAR: HUT13_20065
MTS: MTES_2013
MPAL: BO218_08375
MHOS: CXR34_02900
MLV: CVS47_02892
MICS: C1N74_02585
RFS: C1I64_09310
CUM: NI26_02905
CUB: BJK06_01750
CUG: C1N91_02775
AMAU: DSM26151_02420(oiaC)
PSAI: C3B54_111590
MSPO: KXZ72_09065
GRY: D7I44_10530
LYD: D7I47_03125
PLAP: EAO79_04820
HEA: HL652_16125
FRN: F1C15_12635
ARR: ARUE_c18610
ARQ: BWQ92_12035
ARN: CGK93_09905
PSEY: GU243_03910
BFA: Bfae_31660
BRX: BH708_13645
BGG: CFK41_17135 CFK41_17645
BRZ: CFK38_02960
BSAU: DWV08_13805 DWV08_14430
BKI: M4486_14715
BRHA: NLU66_02695
BHH: Bra3105_11725
HALT: IM660_18435
RHAL: LQF10_18190
RSUA: LQF12_14630 LQF12_15505
PACD: EGX94_08895
PAUS: NCTC13651_02080
MIK: FOE78_11440
MICG: GJV80_00705 GJV80_08910
PDX: Psed_3726
APRE: CNX65_13445
AMI: Amir_2650
ACTI: UA75_20485
ACAD: UA74_19985
ACTA: C1701_04360
PMAD: BAY61_13410
PLAN: A1s21148_07070
KBS: EPA93_17515
PMET: G4Y79_16690
CCZ: CCALI_01065
ROO: G5S37_03845
LCRE: Pla8534_01620
AAGG: ETAA8_01090
BVO: Pan97_07490
TTF: THTE_0223
PEH: Spb1_25330
PLS: VT03_25880
ULI: ETAA1_27670
AGV: OJF2_37210 OJF2_65550(iolE_6)
BHC: JFL75_14395
BPO: BP951000_0042
BPIP: BPP43_02875
BHP: BHAMNSH16_00090
ABAS: ACPOL_4619
SUS: Acid_5326
PFER: IRI77_22095 IRI77_35585
ABAC: LuPra_01810
FVA: FV113G1_33770
FUL: C4N20_07115
FMO: C4N19_04480
FHO: H9Q81_03170
CPOR: BED41_11685
PMUC: ING2E5A_0781
HHY: Halhy_0208 Halhy_1311
CMR: Cycma_4925
CAMU: CA2015_4742
SLI: Slin_3986
SRD: SD10_04050
SMON: AWR27_07855 AWR27_07940
SPIR: CWM47_22110
SPIK: EXU85_19645
SPIB: G8759_20300
STAE: HNV11_12660
RHOZ: GXP67_22910 GXP67_28185
RSI: Runsl_3634 Runsl_4991
RUN: DR864_05830
ALS: DJ013_04995
ADD: HUW48_15235
ASWU: HUW51_23480
FBT: D770_14625
RBI: RB2501_01520
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
[eca:ECA0868]
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.120
IUBMB Enzyme Nomenclature: 4.1.1.120
ExPASy - ENZYME nomenclature database: 4.1.1.120
BRENDA, the Enzyme Database: 4.1.1.120

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (651)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (222)   
   KEGG MGENES (428)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (659)   

Download RDF
DBGET integrated database retrieval system