KEGG   ENZYME: 4.1.1.121
Entry
EC 4.1.1.121                Enzyme                                 
Name
3-oxoisoapionate-4-phosphate decarboxylase;
oiaX (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-oxoisoapionate 4-phosphate carboxy-lyase
Reaction(IUBMB)
3-oxoisoapionate 4-phosphate = L-erythrulose 1-phosphate + CO2 [RN:R12610]
Reaction(KEGG)
R12610
Substrate
3-oxoisoapionate 4-phosphate [CPD:C22278]
Product
L-erythrulose 1-phosphate [CPD:C03394];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. It belongs to the RuBisCO-like-protein (RLP) superfamily. Stereospecificity of 3-oxoisoapionate 4-phosphate has not been determined.
History
EC 4.1.1.121 created 2020
Orthology
K24268  3-oxoisoapionate-4-phosphate decarboxylase
Genes
MMW: Mmwyl1_3120
MME: Marme_1595
MPRI: MP3633_1135
MARD: IBG28_06425
MLO: mll7006
MLN: A9174_13135
MCI: Mesci_5314
MCIC: A4R28_00540
MOP: Mesop_5775
MAM: Mesau_05270
MAMO: A6B35_09510
MESW: A9K65_029050
MESM: EJ066_15505
MHUA: MCHK_0231
MJR: EB229_13270
MERD: EB233_28475
MOH: IHQ72_30660
SME: SM_b20393(rbcL)
SMK: Sinme_3785
SMQ: SinmeB_4281
SMX: SM11_pD1220(rbcL)
SMI: BN406_06279
SMEG: C770_GR4pD1209
SMEL: SM2011_b20393(rbcL)
SMER: DU99_31335
SMD: Smed_3724
RHI: NGR_b22000(rbcL1) NGR_c06470(rbcL2)
SFH: SFHH103_05031(rbcL)
SFD: USDA257_c23120
SIX: BSY16_3626
SAME: SAMCFNEI73_pC0434(rbcL)
SINO: SS05631_b62680
EAD: OV14_b0206(rbcL1)
ARA: Arad_9230(rbcL)
RET: RHE_PF00042(rbcL)
REC: RHECIAT_PC0000964(rbcL)
REL: REMIM1_PF00046
REI: IE4771_PA00099
RLE: pRL120396(cbbl1)
RLT: Rleg2_4649
RLG: Rleg_4762
RLB: RLEG3_07495
RTR: RTCIAT899_PC04845
RHL: LPU83_pLPU83c0539(rbcL)
RGA: RGR602_PA00082 RGR602_PC01940
RHN: AMJ98_PE00045
RPHA: AMC79_PD00971
RHX: AMK02_PD00048
REZ: AMJ99_PD00045
RJG: CCGE525_32340
RHR: CKA34_20615
RGR: FZ934_27725
RAD: CO657_24185 CO657_28385
RII: FFM53_024620
RBAN: J2J98_22025
RRG: J3P73_25285
RLS: HB780_06780
RAW: NE851_33225
RSUL: N2599_21485
RLW: RlegWSM1455_25760
SHZ: shn_27395
SZO: K8M09_21805
SOJ: K6301_18775
OIN: IAR37_15445
OAN: Oant_3067
OAH: DR92_3436
OPS: A8A54_12360
BPSN: NIK97_14660
OCH: CES85_5837
OCR: HGK82_18460
OCL: GTN27_19405
LNE: FZC33_05815
MMED: Mame_04753(rlp2)
AUA: M673_08880
AALA: IGS74_19135
AALM: LUX29_21325
LIZ: LGH83_09605
CMAR: IMCC12053_1019
TPRO: Ga0080559_TMP304
MALU: KU6B_32220
PALX: GQA70_00810
PARR: EOJ32_13855
PLIA: E4191_04050 E4191_17675
PMAU: CP157_00833(rlp2)
PSAP: JHX88_15345
TEC: AKL02_017845
GOY: GLS_c05850
LCK: HN018_21595
ATEE: K9M52_06930
SAWL: NGM29_18835
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
[ara:Arad_9230] [ret:RHE_PF00042]
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.121
IUBMB Enzyme Nomenclature: 4.1.1.121
ExPASy - ENZYME nomenclature database: 4.1.1.121
BRENDA, the Enzyme Database: 4.1.1.121

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (99)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (94)   
   KEGG MGENES (4)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (2)   
Protein domain (6)   
   InterPro (6)   
All databases (113)   

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