KEGG   ENZYME: 4.1.1.121
Entry
EC 4.1.1.121                Enzyme                                 

Name
3-oxoisoapionate-4-phosphate decarboxylase;
oiaX (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-oxoisoapionate 4-phosphate carboxy-lyase
Reaction(IUBMB)
3-oxoisoapionate 4-phosphate = L-erythrulose 1-phosphate + CO2 [RN:R12610]
Reaction(KEGG)
R12610
Substrate
3-oxoisoapionate 4-phosphate [CPD:C22278]
Product
L-erythrulose 1-phosphate [CPD:C03394];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. It belongs to the RuBisCO-like-protein (RLP) superfamily. Stereospecificity of 3-oxoisoapionate 4-phosphate has not been determined.
History
EC 4.1.1.121 created 2020
Orthology
K24268  3-oxoisoapionate-4-phosphate decarboxylase
Genes
MMW: Mmwyl1_3120
MME: Marme_1595
MPRI: MP3633_1135
MARD: IBG28_06425
MLO: mll7006
MLN: A9174_13135
MCI: Mesci_5314
MOP: Mesop_5775
MAM: Mesau_05270
MAMO: A6B35_09510
MHUA: MCHK_0231
SME: SM_b20393(rbcL)
SMX: SM11_pD1220(rbcL)
SMEL: SM2011_b20393(rbcL)
SMER: DU99_31335
SMD: Smed_3724
RHI: NGR_b22000(rbcL1) NGR_c06470(rbcL2)
SFH: SFHH103_05031(rbcL)
SAME: SAMCFNEI73_pC0434(rbcL)
EAD: OV14_b0206(rbcL1)
ARA: Arad_9230(rbcL)
RET: RHE_PF00042(rbcL)
REC: RHECIAT_PC0000964(rbcL)
RLE: pRL120396(cbbl1)
RLG: Rleg_4762
RHL: LPU83_pLPU83c0539(rbcL)
SHZ: shn_27395
OAN: Oant_3067
OAH: DR92_3436
MMED: Mame_04753(rlp2)
MALU: KU6B_32220
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.121
IUBMB Enzyme Nomenclature: 4.1.1.121
ExPASy - ENZYME nomenclature database: 4.1.1.121
BRENDA, the Enzyme Database: 4.1.1.121

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