KEGG   ENZYME: 4.1.1.121
Entry
EC 4.1.1.121                Enzyme                                 
Name
3-oxoisoapionate-4-phosphate decarboxylase;
oiaX (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-oxoisoapionate 4-phosphate carboxy-lyase
Reaction(IUBMB)
3-oxoisoapionate 4-phosphate = L-erythrulose 1-phosphate + CO2 [RN:R12610]
Reaction(KEGG)
R12610
Substrate
3-oxoisoapionate 4-phosphate [CPD:C22278]
Product
L-erythrulose 1-phosphate [CPD:C03394];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. It belongs to the RuBisCO-like-protein (RLP) superfamily. Stereospecificity of 3-oxoisoapionate 4-phosphate has not been determined.
History
EC 4.1.1.121 created 2020
Orthology
K24268  3-oxoisoapionate-4-phosphate decarboxylase
Genes
MMW: Mmwyl1_3120
MME: Marme_1595
MPRI: MP3633_1135
MARD: IBG28_06425
MLO: mll7006
MLN: A9174_13135
MCI: Mesci_5314
MCIC: A4R28_00540
MOP: Mesop_5775
MAM: Mesau_05270
MAMO: A6B35_09510
MESW: A9K65_029050
MESM: EJ066_15505
MHUA: MCHK_0231
MJR: EB229_13270
MERD: EB233_28475
MOH: IHQ72_30660
MMEI: LRP31_29990
MESU: LHFGNBLO_001838
SME: SM_b20393(rbcL)
SMK: Sinme_3785
SMQ: SinmeB_4281
SMX: SM11_pD1220(rbcL)
SMI: BN406_06279
SMEG: C770_GR4pD1209
SMEL: SM2011_b20393(rbcL)
SMER: DU99_31335
SMD: Smed_3724
RHI: NGR_b22000(rbcL1) NGR_c06470(rbcL2)
SFH: SFHH103_05031(rbcL)
SFD: USDA257_c23120
SIX: BSY16_3626
SAME: SAMCFNEI73_pC0434(rbcL)
SINO: SS05631_b62680
ENU: PYH37_000278
SKM: PZL22_001157
EAD: OV14_b0206(rbcL1)
ECAA: J3R84_34875
EAW: ACEP9W_27895(oiaX)
ASAL: CFBP5507_25125
RET: RHE_PF00042(rbcL)
REC: RHECIAT_PC0000964(rbcL)
REL: REMIM1_PF00046
REI: IE4771_PA00099
RLE: pRL120396(cbbl1)
RLT: Rleg2_4649
RLG: Rleg_4762
RLB: RLEG3_07495
RTR: RTCIAT899_PC04845
RHL: LPU83_pLPU83c0539(rbcL)
RGA: RGR602_PA00082 RGR602_PC01940
RHN: AMJ98_PE00045
RPHA: AMC79_PD00971
RHX: AMK02_PD00048
REZ: AMJ99_PD00045
RJG: CCGE525_32340
RHR: CKA34_20615
RGR: FZ934_27725
RAD: CO657_24185 CO657_28385
RII: FFM53_024620
RBAN: J2J98_22025
RRG: J3P73_25285
RLS: HB780_06780
RAW: NE851_33225
RSUL: N2599_21485
RLW: RlegWSM1455_25760
RRHO: PR018_17285
RTU: PR017_17170
ARA: Arad_9230(rbcL)
RBW: RLCC275e_25230
RHIZ: QMO80_004786
RHIB: I8E17_22875
SHZ: shn_27395
SZO: K8M09_21805
SOJ: K6301_18775
SSUM: Q9314_21130
OIN: IAR37_15445
OAN: Oant_3067
OAH: DR92_3436
OPS: A8A54_12360
BPSN: NIK97_14660
BRUC: LJ361_08220
OCR: HGK82_18460
OCL: GTN27_19405
OCC: KMS41_13120
OCH: CES85_5837
LNE: FZC33_05815
MMED: Mame_04753(rlp2)
AUA: M673_08880
AALA: IGS74_19135
AALM: LUX29_21325
LIZ: LGH83_09605
CMAR: IMCC12053_1019
TPRO: Ga0080559_TMP304
MALU: KU6B_32220
PALX: GQA70_00810
PARR: EOJ32_13855
PLIA: E4191_04050 E4191_17675
PMAU: CP157_00833(rlp2)
PSAP: JHX88_15345
MALC: QQG91_14550
TEC: AKL02_017845
GOY: GLS_c05850
LCK: HN018_21595
AAQW: K1X11_002335
TMV: OH491_20060
OBA: ASA1KI_32570
BGOK: Pr1d_30480
TPLA: ElP_03100(cbbL)
ATEE: K9M52_06930
OFA: NF556_16330
SAWL: NGM29_18835
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
[ara:Arad_9230] [ret:RHE_PF00042]
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.121
IUBMB Enzyme Nomenclature: 4.1.1.121
ExPASy - ENZYME nomenclature database: 4.1.1.121
BRENDA, the Enzyme Database: 4.1.1.121

  All links  
Gene (4)   
   MGENES (4)   
Protein sequence (1415)   
   UniProt (7)   
   SWISS-PROT (2)   
   RefSeq(pep) (1406)   
DNA sequence (3384)   
   RefSeq(nuc) (3238)   
   GenBank (75)   
   EMBL (71)   
Protein domain (7)   
   InterPro (7)   
All databases (4810)   

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