KEGG ENZYME: 4.1.1.33

ENZYME: 4.1.1.33

Entry

EC 4.1.1.33 Enzyme

Name

diphosphomevalonate decarboxylase;
pyrophosphomevalonate decarboxylase;
mevalonate-5-pyrophosphate decarboxylase;
pyrophosphomevalonic acid decarboxylase;
5-pyrophosphomevalonate decarboxylase;
mevalonate 5-diphosphate decarboxylase;
ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)

Class

Lyases;
Carbon-carbon lyases;
Carboxy-lyases

Sysname

ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)

Reaction(IUBMB)

ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 [RN:R01121]

Reaction(KEGG)

R01121

Substrate

ATP [CPD:C00002];
(R)-5-diphosphomevalonate [CPD:C01143]

Product

ADP [CPD:C00008];
phosphate [CPD:C00009];
isopentenyl diphosphate [CPD:C00129];
CO2 [CPD:C00011]

History

EC 4.1.1.33 created 1961

Pathway

ec00900

Terpenoid backbone biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

ec01130

Biosynthesis of antibiotics

Orthology

K01597

diphosphomevalonate decarboxylase

Genes

HSA:

4597(MVD)

PTR:	468069(MVD)

PPS:	100986587(MVD)

GGO:	101142252(MVD)

PON:	100436035(MVD)

NLE:	100596968(MVD)

MCC:	696865(MVD)

MCF:	102144157(MVD)

CSAB:

103233450(MVD)

RRO:	104655985(MVD)

RBB:	108520436(MVD)

CJC:	100415332(MVD)

SBQ:	101045742(MVD)

MMU:	192156(Mvd)

MCAL:

110300544(Mvd)

MPAH:

110337595(Mvd)

RNO:	81726(Mvd)

MUN:	110545251(Mvd)

CGE:	100766541(Mvd)

NGI:	103740012(Mvd)

HGL:	101716695(Mvd)

CCAN:

109692740(Mvd)

TUP:	102471567(MVD)

CFA:	489663(MVD)

VVP:	112924622(MVD)

AML:	100482728(MVD)

UMR:	103673954(MVD)

UAH:	113252150(MVD)

ORO:	101365033(MVD)

FCA:	101091985(MVD)

PTG:	102949588(MVD)

AJU:	106973507(MVD)

BTA:	509958(MVD)

BOM:	102270663(MVD)

BIU:	109572734(MVD)

BBUB:

102412728(MVD)

PHD:	102317648(MVD)

CHX:	102169040(MVD)

OAS:	101106706(MVD)

SSC:	110260885(MVD)

CFR:	102517486(MVD)

CDK:	105104684 105104697

BACU:

103009099(MVD)

LVE:	103090803(MVD)

OOR:	101274699(MVD)

DLE:	111179400(MVD)

ECB:	100049914(MVD)

EPZ:	103541851(MVD)

EAI:	106828254(MVD)

MYB:	102241614(MVD)

MYD:	102760535(MVD)

MNA:	107525748(MVD)

HAI:	109389183(MVD)

RSS:	109453190(MVD)

DRO:	112300692(MVD)

PALE:

102885410(MVD)

LAV:	100675507(MVD)

TMU:

101355695

MDO:	100026108(MVD)

SHR:	100930481(MVD)

PCW:	110210309(MVD)

OAA:	100078306(MVD)

GGA:	425359(MVD)

MGP:	100544251(MVD)

CJO:	107319524(MVD)

TGU:	100224697(MVD)

LSR:	110468831(MVD)

SCAN:

103816883(MVD)

GFR:	102036201(MVD)

FAB:	101818721(MVD)

PHI:	102108837(MVD)

PMAJ:

107210058(MVD)

CCAE:

111934406(MVD)

CCW:	104691925(MVD)

ETL:	114060607(MVD)

FPG:	101924675(MVD)

FCH:	102051678(MVD)

CLV:	102091555(MVD)

EGZ:

104125028

NNI:	104010123(MVD)

AAM:	106491415(MVD)

ASN:	102377119(MVD)

AMJ:	102558688(MVD)

PSS:	102449595(MVD)

CMY:	102947224(MVD)

CPIC:

101937073(MVD)

ACS:	100555375(mvd)

PVT:	110076355(MVD)

PBI:	103052529(MVD)

PMUR:

107283477(MVD)

GJA:	107119315(MVD)

XLA:	108714102(mvd.L)

XTR:	394871(mvd)

NPR:	108802190(MVD)

DRE:	492781(mvda)

SRX:	107755554(mvd)

SANH:

107661985(mvd)

SGH:	107550116(mvd)

IPU:	108264584(mvd)

PHYP:

113526794(mvd)

AMEX:

103041437(mvd)

EEE:	113570889(mvd)

TRU:	101079457(mvd)

TNG:	GSTEN00017658G001

LCO:	104927406(mvd)

NCC:	104964891(mvd)

MZE:	101469877(mvd)

OLA:	101159251(mvd)

XMA:	102218884(mvd)

XCO:	114142751(mvd)

PRET:

103462572(mvd)

NFU:	107381321(mvd)

KMR:	108251059(mvd)

CSEM:

103379181(mvd)

LCF:	108877825(mvd)

SDU:	111221663(mvd)

HCQ:	109525909(mvd)

BPEC:

110175244(mvd)

MALB:

109965059(mvd)

SASA:

100195467(erg19) 106562275

OTW:	112249244 112263756

SALP:

111969439 111975040

ELS:	105015965(mvd)

SFM:	108940992(mvd)

PKI:	111861204(mvd)

LCM:	102353500(MVD)

CMK:	103175996(mvd)

BFO:	BRAFLDRAFT_277163

CIN:

SPU:

APLC:

SKO:

DME:	Dmel_CG8239(Mvd)

DPO:	Dpse_GA20922

DAN:	Dana_GF15902

DER:

6550652

DPE:

6603543

DSE:	Dsec_GM22575

DSI:	Dsimw501_GD29521(Dsim_GD29521)

DWI:

6653015

DYA:	Dyak_GE17215

DGR:	Dgri_GH20637

DMO:	Dmoj_GI19000

DAZ:

108617590

DNV:

108654004

DHE:

111593726

DVI:	Dvir_GJ19966

MDE:

101896168

AGA:	AgaP_AGAP001611

AAG:

5564040

CQU:	CpipJ_CPIJ003140

AME:

725817

BIM:	100747232 105680438

BTER:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

MDL:

TCA:

DPA:

NVL:

BMOR:

100101206(Mppd)

DPL:	KGM_204656 KGM_204657

PMAC:

PRAP:

HAW:

TNL:

PXY:

API:	100158798(Mvd) 100160652

DNX:

107166514

AGS:

114121236

CLEC:

106669788

PHU:	Phum_PHUM582500

ZNE:

110827417

FCD:

110856007

DPX:	DAPPUDRAFT_301631

ISC:	IscW_ISCW022273

TUT:

107368820

DPTE:

113789813

CEL:	CELE_Y48B6A.13(Y48B6A.13)

CBR:

CBG20661

BMY:

Bm1_42945

LOA:	LOAG_17225

NAI:	NECAME_14603

TSP:

Tsp_11372

HRO:	HELRODRAFT_185177

LGI:	LOTGIDRAFT_211321

PCAN:

CRG:

MYI:

OBI:

LAK:	106160904 106174024

SMM:	Smp_172660

SHX:

MS3_09923

OVI:	T265_11156

EGL:

EGR_09205

NVE:	NEMVE_v1g118942

EPA:

110236551

ADF:	107345731 107356952

PDAM:

113667514

SPIS:

111342067

HMG:

101239335

TAD:	TRIADDRAFT_55561

AQU:

100639218

ATH:	AT2G38700(MVD1) AT3G54250

ALY:	ARALYDRAFT_482881 ARALYDRAFT_906831

CRB:	17885502 17888883

CSAT:

104712004 104781291 104782317 104785607 104791697

EUS:	EUTSA_v10010411mg EUTSA_v10016888mg EUTSA_v10023484mg

BRP:	103841340 103863245

BNA:	106411721 106413053 106431384 106431385

BOE:	106309559 106343072

THJ:	104811335 104824218

CPAP:

110807119

CIT:

102616609

CIC:	CICLE_v10015368mg

TCC:

18586727

GRA:

105782280

GHI:	107920209 107933302

GAB:

108464430

DZI:

111296207

EGR:	104421719 104454098

GMX:	100785593 100800990

PVU:	PHAVU_007G021200g

VRA:

106772823

VAR:

108326481

CCAJ:

109796777

MTR:	MTR_1g112230

CAM:

101491864

LJA:	Lj5g3v2240960.1(Lj5g3v2240960.1)

ADU:

107467427

AIP:

107618170

LANG:

109336098 109346304 109354374

FVE:

PPER:

PMUM:

PAVI:

MDM:	103408694 103420566 103428439

PXB:

ZJU:

CSV:

CMO:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110634581 110653025

MESC:

110618417 110625089

POP:	7477172 7490899

JRE:	108985489 109002152 109009861

QSU:	111985389 111994030 112019659

VVI:

100251686

SLY:	100134900(MDC) 101254587

SPEN:

107004563 107015872

SOT:	102581346 102604354

CANN:

107850997

NTA:	107759723 107763449 107811776 107817230

NSY:	104239765 104241768

NTO:	104111563 104120310

NAU:	109211711 109219818

INI:	109176891 109186400

SIND:

105155312 105166541 105180099

OEU:	111381017 111384789 111405372 111408343

HAN:	110890680 110911532

LSV:	111913067 111916262

CCAV:

DCR:

BVG:

SOE:

CQI:	110692772 110732714

NNU:

104588425

PSOM:

113311043 113323021

OSA:	4328025 4328034

DOSA:

Os02t0107200-01(Os02g0107200) Os02t0109100-01(Os02g0109100)

OBR:

102702719

BDI:

100830501

ATS:	109758114(LOC109758114) 109785668(LOC109785668)

SBI:

8083094

ZMA:	100282878(IDP726) 103643980 103645978

SITA:

PDA:

EGU:

MUS:

DCT:

PEQ:

AOF:	109825759 109836755

ATR:

18426917

SMO:	SELMODRAFT_135101 SELMODRAFT_268244 SELMODRAFT_420483

PPP:	112282539 112283603

GSL:	Gasu_11870

SCE:	YNR043W(MVD1)

AGO:	AGOS_AGL232C

ERC:

Ecym_2521

KLA:	KLLA0_F10285g

KMX:	KLMA_20246(MVD1)

LTH:	KLTH0A07238g

VPO:	Kpol_1028p24

ZRO:	ZYRO0D17270g

CGR:	CAGL0C03630g

NCS:	NCAS_0A05510(NCAS0A05510)

NDI:	NDAI_0K02340(NDAI0K02340)

TPF:	TPHA_0M01990(TPHA0M01990)

TBL:	TBLA_0F04250(TBLA0F04250)

TDL:	TDEL_0A07770(TDEL0A07770)

KAF:	KAFR_0C04730(KAFR0C04730)

PPA:	PAS_chr1-4_0003

DHA:	DEHA2A13398g

PIC:	PICST_90752

PGU:	PGUG_01095

SPAA:

SPAPADRAFT_132255

LEL:	LELG_01448

CAL:	CAALFM_C100070WA(MVD)

CTP:	CTRG_04280

COT:	CORT_0B10600

CDU:	CD36_00080

CTEN:

CANTEDRAFT_122822

YLI:	YALI0F05632g

CLU:	CLUG_03454

CLUS:

A9F13_01g07282

CAUR:

CJI97_001340

SLB:	AWJ20_2601(MVD1)

NCR:

NCU11381

NTE:	NEUTE1DRAFT117918(NEUTE1DRAFT_117918)

SMP:	SMAC_03607

PAN:	PODANSg1075

TTT:	THITE_136252

MTM:	MYCTH_83048

CTHR:

CTHT_0020910

MGR:

MGG_09750

TMN:	UCRPA7_8815

SSCK:

SPSK_03404

FGR:	FGSG_10424

FPU:	FPSE_07437

FVR:	FVEG_03163

FOX:	FOXG_04972

NHE:	NECHADRAFT_96684

TRE:	TRIREDRAFT_22798

MAW:

MAC_01750

MAJ:

MAA_05445

CMT:

CCM_08582

VAL:	VDBG_02883

VDA:	VDAG_03794

CFJ:	CFIO01_02581

ELA:	UCREL1_11668

PFY:	PFICI_08852

SSL:	SS1G_03958

BFU:	BCIN_04g01890(Bcmvd1)

MBE:

MBM_08033

PSCO:

LY89DRAFT_688542

GLZ:	GLAREA_09016

ANI:

AN4414.2

AFM:	AFUA_4G07130

AOR:	AO090023000862

ANG:	ANI_1_332184(An04g01540)

AFV:	AFLA_112720

ACT:	ACLA_046440

NFI:	NFIA_109090

PCS:	Pc22g18320

PDP:	PDIP_12890

CIM:	CIMG_11269(CIMG04156)

CPW:	CPC735_002620

PBL:	PAAG_07591

PBN:	PADG_08290

URE:	UREG_05590

ABE:

ARB_01602

TVE:

TRV_03551

AJE:	HCAG_05596

PNO:	SNOG_04832

PTE:

PTT_07872

BZE:	COCCADRAFT_30615

BSC:	COCSADRAFT_272231

BOR:	COCMIDRAFT_5789

AALT:

CC77DRAFT_1022328

ZTR:	MYCGRDRAFT_77157(MVD1)

PFJ:	MYCFIDRAFT_71007

BCOM:

BAUCODRAFT_462693

NPA:	UCRNP2_5741

TML:	GSTUM_00005252001

SPO:	SPAC24C9.03(mvd1)

CNE:

CNL04950

CNB:

CNBI1880

CGI:	CGB_D2120W

TMS:	TREMEDRAFT_67459

TVS:	TRAVEDRAFT_160627

DSQ:	DICSQDRAFT_94421

SHS:	STEHIDRAFT_171117

HIR:	HETIRDRAFT_247911 HETIRDRAFT_440521

PSQ:	PUNSTDRAFT_83965

ADL:	AURDEDRAFT_111357

FME:	FOMMEDRAFT_123441

GTR:	GLOTRDRAFT_127445

LBC:	LACBIDRAFT_190457 LACBIDRAFT_228351

MPR:	MPER_05313

MRR:	Moror_3021

CCI:	CC1G_02299

SCM:	SCHCODRAFT_69496

ABP:	AGABI1DRAFT116646(AGABI1DRAFT_116646)

ABV:	AGABI2DRAFT196085(AGABI2DRAFT_196085)

CPUT:

CONPUDRAFT_136458

SLA:	SERLADRAFT_466408

WSE:	WALSEDRAFT_40592

WIC:	J056_002706

UMA:	UMAG_05179

PFP:	PFL1_03071

MGL:

MGL_1650

PGR:	PGTG_02786 PGTG_06637

MLR:	MELLADRAFT_74468

ECU:	ECU06_0490

EIN:	Eint_060410

EHE:	EHEL_060440

ERO:	EROM_060420

MBR:	MONBRDRAFT_26828

SRE:	PTSG_09366

DDI:	DDB_G0278607(mvd)

DPP:	DICPUDRAFT_32847

DFA:	DFA_02777(mvd)

ACAN:

ACA1_175080

TET:	TTHERM_00849200

PTM:	GSPATT00008724001

PTI:	PHATRDRAFT_bd1325(MPDC)

FCY:	FRACYDRAFT_183994

TPS:	THAPSDRAFT_15226

AAF:	AURANDRAFT_30852

PIF:	PITG_15778

PSOJ:

PHYSODRAFT_500398

SPAR:

SPRG_03870

EHX:	EMIHUDRAFT_445262(MVD1)

GTT:	GUITHDRAFT_158994

TBR:	Tb10.05.0010 Tb10.61.2745

TCR:	507993.330 511281.40

LMA:	LMJF_18_0020

LIF:	LINJ_18_0020

LDO:	LDBPK_180020

LMI:	LMXM_18_0020

LBZ:	LBRM_18_0030

NGR:	NAEGRDRAFT_59992

TVA:	TVAG_302660

GLA:	GL50803_23420

RHD:	R2APBS1_3945

DYE:	EO087_12930(mvaD)

PSIL:

PMA3_24035

MBS:	MRBBS_1939

MPQ:	ABA45_09090

TTU:	TERTU_3245(mvaD)

CBU:	CBU_0607(mvaD)

CBS:	COXBURSA331_A0720(mvaD_idi)

CBD:	CBUD_0619(mvaD_idi)

CBG:	CbuG_1396(mvaD)

CBC:	CbuK_1443(mvaD)

CEA:	Z664_00890

CEY:	CleRT_04130

LPN:

lpg2040

LPH:

LPV_2344

LPO:

LPO_2143

LPU:	LPE509_01138

LPM:	LP6_2020(mvaD)

LPF:

lpl2018

LPP:

lpp2023

LPC:

LPC_1526

LPA:	lpa_02977(mVD1)

LPE:

LLO:

LFA:

LHA:

LOK:

LCD:	clem_02865

LES:	CCU22_01535

LSH:	CAB17_15810

LLG:	44548918_02243

LIB:	E4T55_03295

TMC:

LMI_2748

TCX:

Tcr_1734

HTR:	EPV75_09325(mvaD)

TCY:	Thicy_1414

TAO:	THIAE_09055

THIO:

AYJ59_04610

PSAL:

PSLF89_04480

WMA:	WM2015_1904

WOC:	BA177_02275

HAA:	A5892_16345

MARS:

A8C75_06255

DNO:	DNO_0504(mvaD)

CHJ:	NCTC10426_00494

SALN:

SALB1_2162

MXA:	MXAN_5018(mvaD)

MFU:	LILAB_32975

MSD:	MYSTI_05503

MYM:	A176_001873

MMAS:

MYMAC_004895

CCX:	COCOR_02448(mvaD)

SUR:	STAUR_5823(mvaD)

AGE:	AA314_03813

MBD:	MEBOL_005715

CFUS:

CYFUS_006869

SCL:

sce4206

SCU:	SCE1572_25540

CCRO:

CMC5_040780(mvaD)

SAMY:

DB32_000806

LLU:	AKJ09_08296

MRM:	A7982_03100

HOH:

Hoch_3408

BSED:

DN745_12075(mvaD)

BBA:

BBAT:

BBW:

BBAC:

BEX:

BDQ:	CIK05_06965

BMX:	BMS_1479(mvaD)

HAX:	BALOs_1467

BSTO:

C0V70_08570

SBF:	JCM31447_316500

LAS:	CLIBASIA_04590(mvaD)

LAA:

WSI_04425

LAT:	CGUJ_04590(mvaD)

LSO:

CKC_03825

LCC:	B488_07260

LAR:	lam_727(mVD1)

LAU:	G293_00050

RSU:	NHU_01020(mvaD)

RHM:	B5V46_13605

SDO:	SD1155_05730(mvaD)

BCK:	BCO26_0257

BAG:

Bcoa_0982

BCOA:

BF29_2754(mvaD)

OIH:

OB0226

OCN:	CUC15_01200(mvaD)

AXL:	AXY_02830(mvaD)

VIR:	X953_01230

VHL:	BME96_01195

VIG:	BKP57_12125

VIL:	CFK37_04980(mvaD)

VNE:	CFK40_00650(mvaD)

VPN:	A21D_01099(thrB_2)

LAO:	AOX59_12525

STEA:

C0679_13270(mvaD)

SAU:	SA0548(mvaD)

SAV:	SAV0591(mvaD)

SAW:	SAHV_0589(mvaD)

SAH:	SaurJH1_0629

SAJ:	SaurJH9_0614

SAM:	MW0546(mvaD)

SAS:

SAS0550

SAR:	SAR0597(mvaD)

SAC:	SACOL0637(mvaD)

SAX:	USA300HOU_0584(mvaD)

SAA:	SAUSA300_0573(mvaD)

SAO:	SAOUHSC_00578

SAE:	NWMN_0554(mvaD)

SAD:	SAAV_0553(mvaD)

SUU:	M013TW_0579

SUV:	SAVC_02540

SUE:

SAOV_0625

SUJ:	SAA6159_00544(mvaD)

SUK:	SAA6008_00598(mvaD)

SUC:	ECTR2_544(mvaD)

SUT:	SAT0131_00654

SUQ:	HMPREF0772_12597(mvaD)

SUZ:	MS7_0580(mvaD)

SUD:	ST398NM01_0665

SUX:	SAEMRSA15_05190(mvaD)

SUW:	SATW20_06600(mvaD)

SUG:	SAPIG0665(mvaD)

SUF:	SARLGA251_05260(mvaD)

SAUA:

SAAG_01013

SAUE:

RSAU_000543(mvaD)

SAUN:

SAKOR_00582

SAUS:

SA40_0532(mvaD)

SAUU:

SA957_0547(mvaD)

SAUG:

SA268_0545(mvaD)

SAUZ:

SAZ172_0594(mvaD)

SAUT:

SAI1T1_2004550(mvaD)

SAUJ:

SAI2T2_1004570(mvaD)

SAUK:

SAI3T3_1004560(mvaD)

SAUQ:

SAI4T8_1004550(mvaD)

SAUV:

SAI7S6_1004560(mvaD)

SAUW:

SAI5S5_1004520(mvaD)

SAUX:

SAI6T6_1004530(mvaD)

SAUY:

SAI8T7_1004560(mvaD)

SAUF:

X998_0632(mvaD)

SAB:	SAB0541(mvaD)

SUY:	SA2981_0568(mvaD)

SAUB:

C248_0666(mvaD)

SAUM:

BN843_5840

SAUC:

CA347_606(mvaD)

SAUR:

SABB_00640(mvaD)

SAUI:

AZ30_02985

SAUD:

CH52_02805

SAMS:

NI36_02945

SUH:	SAMSHR1132_05350

SEP:

SE0362

SER:	SERP0239(mvaD)

SEPP:

SEB_00284

SEPS:

DP17_1669(mvaD)

SHA:	SH2401(mvaD)

SHH:	ShL2_02196(mvaD)

SSP:

SSP2121

SCA:	SCA_0245(mvaD)

SLG:	SLGD_02294

SLN:	SLUG_22100(mvaD)

SWA:	A284_10350

SPAS:

STP1_1677

SXY:	BE24_00750

SXL:	SXYLSMQ121_2104

SXO:	SXYL_02257(mvaD)

SCAP:

AYP1020_2341

SEQO:

SE1039_04200

SSIF:

AL483_08600(mvaD)

SCV:	A4G25_06455

SPET:

CEP67_09960(mvaD)

SSCU:

CEP64_00095(mvaD)

SNL:	BJD96_11925

SKL:	C7J89_12490(mvaD)

LMO:

lmo0011

LMN:	LM5578_3011

LMY:	LM5923_2960

LMT:	LMRG_02440

LMOE:

LMOB:

LMOD:

LMOW:

LMOQ:

LMR:	LMR479A_0011

LMOM:

IJ09_10350

LMF:	LMOf2365_0012(mvaD)

LMC:	Lm4b_00011

LMOG:

BN389_00120(MVD1)

LMP:

MUO_00060

LMOJ:

LM220_16192

LMOZ:

LM1816_16755(mvaD)

LMOX:

AX24_12545

LMH:	LMHCC_2652(mvaD)

LMQ:	LMM7_0012(mvaD)

LML:	lmo4a_0011(mvaD)

LMG:	LMKG_02322

LMS:

LMLG_2922

LMJ:	LMOG_01621

LMOK:

CQ02_00060

LMV:	Y193_01240

LIN:

lin0011

LWE:	lwe0012(mvaD)

LSG:	lse_0011(mvaD)

LIV:

LIV_0011

LII:	JL52_00305

LIW:	AX25_00315

LIA:	JL58_00240

LIO:	JL53_00240

BTHS:

CNY62_05485(mvaD)

GOT:	AXE85_01885

GMO:	NCTC11323_00247

GEQ:	CG018_03655(mvaD)

PCX:	LPB68_16755

LLA:	L9089(yeaH)

LLK:	LLKF_0457(mvaD)

LLT:	CVCAS_0388(mvaD)

LLS:	lilo_0368(yeaH)

LLD:	P620_02545(mvaD)

LLX:	NCDO2118_0464(mvaD)

LLC:

LACR_0455

LLM:	llmg_0426(mvaD)

LLR:

llh_2375

LLN:	LLNZ_02220

LLI:	uc509_0432(mvaD)

LLW:	kw2_0407(mvaD)

LLJ:	LG36_0404(mvaD)

LGR:

LCGT_0282

LGV:

LCGL_0282

LACT:

D7I46_12585(mvaD)

SPY:	SPy_0877(mvaD)

SPZ:	M5005_Spy0683(mvaD)

SPYM:

M1GAS476_0742(mvaD)

SPYA:

A20_0724(mvaD)

SPM:	spyM18_0938(mvd)

SPG:	SpyM3_0596(mvaD)

SPS:

SPs1257

SPH:	MGAS10270_Spy0741(mvaD)

SPI:	MGAS10750_Spy0775(mvaD)

SPJ:	MGAS2096_Spy0754(mvaD)

SPK:	MGAS9429_Spy0738(mvaD)

SPF:	SpyM51125(mvaD)

SPA:	M6_Spy0700

SPB:	M28_Spy0663(mvaD)

STG:	MGAS15252_0708(mvaD)

STX:	MGAS1882_0704(mvaD)

SOZ:	Spy49_0691(mvaD)

STZ:	SPYALAB49_000709(mvaD)

SPYH:

L897_03580

SPN:	SP_0382(mvaD)

SPD:	SPD_0347(mvaD)

SPR:	spr0339(mvd1)

SPW:	SPCG_0377(mvd1)

SJJ:	SPJ_0369(mvaD)

SNV:	SPNINV200_03440(mvaD)

SPX:	SPG_0347(mvaD)

SNT:	SPT_0427(mvaD)

SND:

MYY_0461

SPNN:

T308_01900

SNE:	SPN23F03540(mvaD)

SPV:	SPH_0489(mvaD)

SNC:	HMPREF0837_10680(mvaD)

SNM:	SP70585_0453(mvaD)

SPP:	SPP_0420(mvaD)

SNI:	INV104_03290(mvaD)

SPNG:

HMPREF1038_00433(mvaD)

SNB:	SP670_0450(mvaD)

SNP:

SPAP_0409

SNX:	SPNOXC03790(mvaD)

SNU:	SPNA45_01668

SPNE:

SPN034156_14350(mvaD)

SPNU:

SPN034183_03850(mvaD)

SPNM:

SPN994038_03730(mvaD)

SPNO:

SPN994039_03740(mvaD)

SAG:	SAG1325(mvaD)

SAN:

gbs1395

SAK:	SAK_1356(mvaD)

SGC:	A964_1239(mvaD)

SAGS:

SaSA20_1070

SAGL:

GBS222_1079(mvaD)

SAGM:

BSA_14040

SAGI:

MSA_14460

SAGR:

SAIL_13700 SAIL_13710

SAGP:

SAGC:

SAGT:

SAGE:

SAGG:

SAGN:

W903_1338(mvaD)

SMU:

SMU_937

SMC:	SmuNN2025_1091

SMUT:

SMUGS5_04140

SMJ:	SMULJ23_1088(mvaD)

SMUA:

SMUFR_0815(mvaD)

STC:	str0560(mvaD)

STL:	stu0560(mvaD)

STE:

STER_0599

STN:

STND_0557

STU:	STH8232_0740(mvaD)

STW:

Y1U_C0534

STHE:

T303_03935

STHS:

AVT04_02130

SSA:	SSA_0334(mvaD)

SSB:	SSUBM407_0261(mvaD)

SSU:	SSU05_0290

SSV:	SSU98_0286

SSI:	SSU0270(mvaD)

SSS:	SSUSC84_0259(mvaD)

SSF:	SSUA7_0271

SSW:	SSGZ1_0266

SUP:

YYK_01265

SSUS:

NJAUSS_0278

SST:	SSUST3_0299(mvaD)

SSUY:

YB51_1455

SSK:	SSUD12_0268

SSQ:	SSUD9_0320(mvaD)

SUI:	SSUJS14_0276

SUO:	SSU12_0274

SRP:	SSUST1_0287(mvaD)

SSUT:

TL13_0316

SSUI:

T15_0281(mvaD)

SGO:	SGO_0240(mvaD)

SEZ:

Sez_1083

SEQ:

SZO_08840

SEZO:

SeseC_01426(mvaD)

SEQU:

Q426_03670

SEU:

SEQ_1105

SUB:	SUB0766(mvaD)

SDS:	SDEG_0834(mvaD)

SDG:	SDE12394_04460

SDA:	GGS_0802(mvaD)

SDC:	SDSE_0871(mvaD)

SDQ:	SDSE167_0899(mvaD)

SGA:	GALLO_1265

SGG:	SGGBAA2069_c12560(mvaD)

SGT:	SGGB_1259(mvaD)

SMB:

smi_1746

SOR:

SOR_1630

STK:	STP_0601(mvaD)

STB:	SGPB_1175(mvaD)

SCP:	HMPREF0833_11233(mvaD)

SCF:	Spaf_1827(mvaD)

SSR:	SALIVB_1532(mvd1)

STF:	Ssal_01607(mvaD)

STJ:	SALIVA_0565(mvd1)

STRS:

SSAL8618_02945

SSAH:

HSISS4_00471(mvaD)

STD:	SPPN_02310

SMN:

SMA_1194

SIF:	Sinf_1096(mvaD)

SIE:	SCIM_0182(mvaD)

SIB:	SIR_0240(mvaD)

SIU:	SII_0226(mvaD)

SANG:

SAIN_0165(mvaD)

SANC:

SANR_0189(mvaD)

SANS:

DK43_09295

SCG:	SCI_0243(mvaD)

SCON:

SCRE_0223(mvaD)

SCOS:

SCR2_0223(mvaD)

SOI:	I872_09050

SIK:

K710_1156

SIQ:	DQ08_05310

SIO:	DW64_05305

SIZ:	SI82_05495

SLU:

KE3_1158

SIG:	N596_06080

SIP:	N597_07950

STV:	V470_07985

SPAT:

A0O21_03780

STRA:

ATM98_05890

STRN:

SNAG_1574(thrB_2)

SSOB:

DK181_05525(mvaD)

SRQ:	SR187_1490

LPL:	lp_1734(mvaD)

LPJ:	JDM1_1457(mvaD)

LPT:	zj316_1726(mvaD)

LPS:	LPST_C1387(mvaD)

LPR:	LBP_cg1336

LPZ:

Lp16_1334

LPB:	SH83_07215

LJO:

LJ_1206

LJF:	FI9785_974(mvaD)

LJH:

LJP_0956c

LJN:	T285_04745

LAC:	LBA1168(mvaD)

LAI:	LAC30SC_06225

LAD:

LA14_1179

LAF:	SD55_1173(mvaD)

LSA:	LCA_0907(mvaD)

LSL:

LSL_0684

LSI:

HN6_00603

LSJ:

LSJ_0745c

LDB:	Ldb0998(mvaD)

LBU:

LBUL_0905

LDE:	LDBND_0893

LDL:

LBU_0848

LBR:

LVIS_0859

LBK:	LVISKB_1120

LCA:

LSEI_1492

LCZ:	LCAZH_1484

LPQ:	AF91_06415

LPI:	LBPG_00339

LPAP:

LBPC_1414

LCB:	LCABL_17140(mvaD)

LCS:

LCBD_1697

LCE:

LC2W_1665

LCW:	BN194_16830(mvd1)

LCL:	LOCK919_1669

LCX:	LCA12A_0830

LGA:

LGAS_1034

LRE:

Lreu_0914

LRF:

LAR_0861

LRU:	HMPREF0538_22183(mvaD)

LRT:

LRI_1055

LRR:	N134_04955

LHE:

lhv_1276

LHL:

LBHH_0883

LHR:	R0052_05170

LHV:

LHH:

LHD:

LFE:

LFR:

LFF:

LRH:	LGG_01499(mvaD)

LRG:

LRHM_1439

LRL:	LC705_01514(mvaD)

LRA:	LRHK_1501(mvaD)

LRO:	LOCK900_1472

LRC:	LOCK908_1562

LCR:	LCRIS_01176(mvaD)

LAM:

LA2_06580

LAY:	LAB52_05955

LBH:

Lbuc_1067

LBN:	LBUCD034_1202(mvaD)

LKE:	WANG_0508(mvaD)

LRM:

LRC_09030

LSN:

LSA_06980

LAW:	LACWKB8_0957

LHO:	LOOC260_110680(mvaD)

LMU:	LBLM1_04335

LAE:

LBAT_0872

LGN:	ABM34_02835

LKO:	ABN16_13005

LHI:	JP39_05840

LKU:	APS55_06675

LGL:	AO203_09225

LPX:	ASU28_07215

LOR:	AYI71_12965

LPAR:

FAM21731_02396

LLE:	AYR59_05570

LPD:	AYR62_06555

LJE:	BUE77_04440

LCU:	PL11_009145

LCT:	BI355_1050

LBT:	AYR52_04280

LCV:	FBA2_05090

LAH:	LA20533_08170

LAMY:

B1745_03425

LAGL:

BEN83_04655

LZY:	LZ3411_1354

LPG:	BB562_08740

LCY:	LC20004_08060

LACA:

LAC1533_1274

LALW:

BTM29_09695

LALI:

LA20249_03070

LPW:	LpgJCM5343_09150(mvaD)

PPE:

PEPE_0926

PPEN:

T256_04525

PCE:	PECL_1023(mvaD)

PDM:	ADU72_2083

PACI:

A4V11_01555

PIO:	PI20285_03995

EFA:	EF0903(mvaD)

EFL:	EF62_1276(mvaD)

EFI:	OG1RF_10630(mvd)

EFD:	EFD32_0714

EFS:	EFS1_0728(mvaD)

EFN:	DENG_00954(mvaD)

EFQ:	DR75_2839(mvaD)

ENE:

ENT_21860

EFC:	EFAU004_00259

EFAU:

EFAU085_00217

EFU:	HMPREF0351_10224(mvaD)

EFM:

M7W_446

EFT:	M395_01225

EHR:

EHR_03660

ECAS:

ECBG_02455

EMU:

EMQU_0240

EGA:	AL523_02350(mvaD)

ESS:	ATZ33_16745

ETH:	CK496_01040(mvaD)

EGV:	EGCR1_13975(mvaD)

MPS:

MPTP_0700

MPX:

MPD5_1231

THL:	TEH_02170(mvaD)

TOO:	C7K38_03535(mvaD)

TKR:	C7K43_09610(mvaD)

VTE:	BHY08_07375

VPI:	BW732_03860

VAC:	E4Z98_04780(mvaD)

VAO:	FA707_05120(mvaD)

OEN:	DSM07_00160(mvaD)

OSI:	DLJ48_08270(mvaD)

LME:

LEUM_1386

LMM:

MI1_06090

LMK:

LMES_1164

LCI:	LCK_00622(mvaD)

LKI:

LKI_01540

LEC:	LGMK_01140

LCN:	C270_04915

LGS:	LEGAS_1194(mvaD)

LGE:	C269_05930

LLF:	BCR17_01055

LGC:	A9176_05550

LSU:	A6B45_06530

WKO:

WKK_06215

WCE:

WS08_0630

WCT:

WS74_0632

WCI:	WS105_0692

WCB:	AO080_08185

WJO:	FOL01_0978

WPA:	CO680_03470(mvaD)

WCF:	C6P13_06105(mvaD)

AUR:	HMPREF9243_0782(mvaD)

AUN:	AWM73_05750

AUI:	APT62_03950

ASAN:

AWM72_07655

ACG:	AWM71_05720

AVS:	AWM76_06445

AUH:	AWM75_07515

ABAE:

CL176_10720(mvaD)

CRN:	CAR_c18450(mvaD)

CML:	BN424_2926(mvaD)

CAW:	Q783_08430

CARC:

NY10_1276

CDJ:	BFC22_11765

MARR:

BKP56_05375

JEP:	BW721_01020

JDA:	BW727_101265(thrB_2)

JEH:	EJN90_01175(mvaD)

FSA:	C5Q98_02155(mvaD)

LBW:	C3V36_09070(mvaD)

ERH:	ERH_1526(mvaD)

ERS:	K210_06120

ERL:	AOC36_01640

ERI:	EEI45_02555(mvaD)

ACL:	ACL_0799(mvaD)

APAL:

BN85409460(mvaD)

AOC:	Aocu_09100(mvaD)

AAXA:

MUL:

MMI:

MMAE:

MLI:	MULP_03442

CKP:	ckrop_0027(mvaD)

CVA:	CVAR_0903(mvaD)

CTER:

A606_03535

CGY:	CGLY_05840(mvaD)

COA:	DR71_1487(mvaD)

CLW:	CLAC_02235

CSPH:

CSPHI_01945

NFA:

NFA_22080

NFR:	ERS450000_01890

NBR:	O3I_007935 O3I_033240

NSR:	NS506_07099(mvaD)

DTM:	BJL86_0264

SDV:	BN159_7951

SFK:

KY5_0605c

MIO:	AOA12_09740

MPAL:

BO218_02460

CUM:	NI26_12905

CUB:	BJK06_11780

PLAP:

EAO79_16945(mvaD)

LTR:	EVS81_04290(mvaD)

AUL:	DCC27_011080(mvaD)

BRX:	BH708_11760

BRV:	CFK39_07205(mvaD)

DVA:	DAD186_12920

IDO:

I598_0508

ORN:	DV701_01015(mvaD)

BLY:	A2T55_01000

PPC:	HMPREF9154_0775(mvaD)

PBO:	PACID_26700

AACI:

ASQ49_08695

ACIJ:

JS278_00856

AJI:	C0Z10_02635(mvaD)

MICB:

MicB006_2919

ASG:	FB03_00080

ACQ:	AM609_08005

AOS:	AXE84_09390

ARD:	AXF14_08830

ACTO:

C3V41_01505(mvaD)

ANE:	AN27039_2221

FSL:	EJO69_10200(mvaD)

FLH:	EJ997_11965(mvaD)

BACT:

AB656_06355

GVA:	HMPREF0424_0313(mvaD)

GVG:	HMPREF0421_21152(mvd)

GVH:	HMPREF9231_0384(mvaD)

SIJ:

SCIP_1429

PDO:

PSDT_1531

RRS:	RoseRS_4285

RCA:

Rcas_0936

CAU:

Caur_0617

CHL:	Chy400_0667

CAG:

Cagg_3390

HAU:

Haur_1612

ATM:	ANT_19910(mvaD)

ABAT:

CFX1CAM_0477(mvaD)

PSUB:

Pelsub_P2025

ABAO:

BEQ56_00050

CAP:	CLDAP_25600(mvaD)

WCH:

wcw_1118

VBL:	L21SP4_02095

BBU:	BB_0686(mvaD)

BBZ:	BbuZS7_0706(mvaD)

BBN:	BbuN40_0686(mvaD)

BBJ:	BbuJD1_0686(mvaD)

BBUR:

BGA:

BGB:

BGN:

BGS:	X921_00805

BGC:	BLA33_00805

BAF:	BAPKO_0730

BAFZ:

BafPKo_0711(mvaD)

BAFH:

BafHLJ01_0756

BAFT:

P612_03545

BAFE:

BAFK78_695(mvaD)

BBS:	BbiDN127_0697(mvaD)

BVT:	P613_03505

BCHI:

BMAY:

BTU:

BHR:

BHI:	L283_03440

BDU:	BDU_689(mvaD)

BRE:	BRE_692(mvaD)

BCW:

Q7M_695

BMO:	I871_03585

BMIY:

RJ61_03365

BPAK:

X966_03485

BANE:

N187_03385

BTUR:

DB313_03585(mvaD)

SFC:	Spiaf_0374

SLR:	L21SP2_2962

LBA:

Lebu_0141

LEO:	AMK43_01935

LOT:	AXF11_04655

LEQ:	BCB68_02500

SMF:

Smon_1123

SNS:	VC03_01140

BLQ:	L21SP5_00848

ASX:	CDL62_00355(mvaD)

MBAS:

ALGA_1995

HHY:	Halhy_2997

SGN:	SGRA_1195(mvaD)

FLI:	Fleli_3326

GFO:

GFO_3632

GRL:	LPB144_08990

GFL:

GRFL_1795

GRS:	C7S20_03870(mvaD)

FJO:

Fjoh_1389

FJG:	BB050_01227

FPS:	FP0310(mvaD)

FPC:	FPSM_00347

FPY:	FPG101_01725

FPO:	FPG3_01700

FPQ:	IB65_01425

FPV:	IA03_01490

FPW:	IA04_01425

FPK:	IA06_01480

FPSZ:

AMR72_12215

FBR:	FBFL15_2226(mvaD)

FCO:	FCOL_04305

FIN:	KQS_12355(mvaD)

FGL:	EM308_02185

FCM:	BIW12_04545

FFA:	FFWV33_06355

FAT:	DVK85_07810

FKI:	FK004_07485

COC:

Coch_0497

CCM:	Ccan_15750

COL:	AM608_06200

CHG:	AXF12_00360

CAPN:

CBG49_01895

CGH:	CGC50_05820

CLK:	CGC53_04595

CSPU:

CCYN:

CAPH:

CSTO:

CAPQ:

RBI:	RB2501_08645

ZPR:

ZPR_4210

CAT:	CA2559_04605

RAN:	Riean_0643

RAI:

RAR:

RAG:

RAE:

RAT:

FBC:	FB2170_08214

MARM:

MART:

MARB:

MARE:

CAO:	Celal_0972

CLY:	Celly_0839

CLH:	IX49_03990

CBAL:

M667_02725

CBAT:

M666_02725

WVI:	Weevi_1102

KDI:	Krodi_1450

DOK:	MED134_10840

DDO:

I597_0937

DOD:	DCS32_04675

LAN:	Lacal_0660

LVN:	BWR22_13855

LACI:

CW733_10435

ZGA:	ZOBELLIA_1243(mvdA)

MRS:	Murru_0943

MLT:

VC82_1028

ASL:	Aeqsu_1673

AEV:	EI546_13415

ORH:	Ornrh_0701

ORI:	Q785_04035

PTQ:	P700755_002479

NDO:	DDD_1963(mvaD)

NOM:	AAT17_09180

NSD:	BST91_09660

NOB:	CW736_02405

NOJ:	EJ995_04865

POM:	MED152_11394(mvaD)

POB:	LPB03_07560

PRN:	BW723_01335

POLA:

BXQ17_07690

POA:	CW731_13565

EAO:

BD94_3087

EMN:	M876_12890

EEN:	BBD30_10835

ELB:	VO54_03471

EMG:	BBD33_07490

EGO:	BBD34_05245

EGM:	AYC65_01460

MYR:	MYRA21_1586

MPW:

MPR_0409

MOD:	AS202_07515

MYZ:	BK054_07395

CHZ:

CHSO_3732

CGN:	OK18_01315

CIH:	ATE47_10160

CHH:	A0O34_15525

CIO:	CEQ15_12225

CHRY:

CPIP:

CTAK:

CHRS:

CHRZ:

CARH:

CSHA:

WIN:

WIJ:	BWZ20_06840

SZE:	AW14_01805

AHZ:	APS56_09065

SYI:	SB49_09905

TDI:	AUW17_10745

TEN:	LPB136_13245

TJE:	TJEJU_1038(mvaD)

TMAR:

MARIT_0616(mvaD)

LUT:	Lupro_05660

LUL:	LPB138_07070

WFU:	AXE80_11065

FOR:	FORMB_08620

FOH:	FORMA_08750

SALT:

AO058_05960

SEON:

BWZ22_09330

AALG:

AREALGSMS7_00787

OLL:	CW732_06450

OAQ:	DZC78_12980

FEK:	C1H87_16385

TAJ:	C1A40_08575

AUE:	C5O00_07410

SPON:

HME9304_01049(mvaD)

KOS:	KORDIASMS9_00590

MARF:

CJ739_909

AQB:	D1818_16895

AQA:	D1815_14510

AQD:	D1816_19790

EMAR:

D1013_18300(mvaD)

CNR:	EB819_07200(mvaD)

MUR:	EQY75_11260

PSYN:

E9099_03715

FBA:

FIC_01859

FBU:	UJ101_01463(MVD\|mvaD)

BBL:	BLBBGE_357(mvaD)

BPI:

BPLAN_283

BCP:	BLBCPU_337(mvaD)

BBG:	BGIGA_277(mvaD)

BBQ:	BLBBOR_356

BLP:	BPAA_287(mvaD)

BLU:

K645_1656

FTE:	Fluta_3217

OHO:	Oweho_1866

ISE:	JBKA6_0472

CABY:

Cabys_3844

PRF:	PeribacterA2_0670

TMG:	US01_C0001G0070(mvaD)

MIB:	UY43_C0001G1160(mvaD)

STO:	STK_09770(mvaD)

SSO:

SSO2989

SOL:

Ssol_0783

SSOA:

SULA_0774(mvaD)

SSOL:

SULB_0776(mvaD)

SSOF:

SULC_0774(mvaD)

SAI:	Saci_1245(mvd)

SACN:

SacN8_06080

SACR:

SacRon12I_06075

SACS:

SUSAZ_05940

SIS:	LS215_2535

SIA:	M1425_2362

SIM:	M1627_2440

SID:

M164_2369

SIY:	YG5714_2509

SIN:	YN1551_0397

SII:

SIH:

SIR:

SIC:

SULA:

MSE:

MCN:

MHK:	DFR87_10865(mvaD)

MPRU:

DFR88_10420(mvaD)

AHO:

Ahos_1490

AMAN:

B6F84_11915

ABRI:

DFR85_11325(mvaD)

ASUL:

DFR86_10160(mvaD)

SACD:

HS1genome_0062

AGW:	QT03_C0001G1032

» show all

Reference

1 [PMID:13801508]

Authors

BLOCH K, CHAYKIN S, PHILLIPS AH, DE WAARD A.

Title

Mevalonic acid pyrophosphate and isopentenylpyrophosphate.

Journal

J Biol Chem 234:2595-604 (1959)

Other DBs

ExplorEnz - The Enzyme Database:

4.1.1.33

IUBMB Enzyme Nomenclature:

4.1.1.33

ExPASy - ENZYME nomenclature database:

4.1.1.33

BRENDA, the Enzyme Database:

4.1.1.33

CAS:

9024-66-2

DBGET integrated database retrieval system