Entry |
|
Name |
acetolactate decarboxylase;
alpha-acetolactate decarboxylase;
(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase;
(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming];
(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(3R)-3-hydroxybutan-2-one-forming]
|
Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
|
Sysname |
(2S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(3R)-3-hydroxybutan-2-one-forming]
|
Reaction(IUBMB) |
(2S)-2-hydroxy-2-methyl-3-oxobutanoate = (3R)-3-hydroxybutan-2-one + CO2 [RN: R02948]
|
Reaction(KEGG) |
|
Substrate |
(2S)-2-hydroxy-2-methyl-3-oxobutanoate [CPD: C06010]
|
Product |
(3R)-3-hydroxybutan-2-one;
CO2 [CPD: C00011]
|
History |
EC 4.1.1.5 created 1961
|
Pathway |
ec00660 | C5-Branched dibasic acid metabolism |
|
Orthology |
K01575 | acetolactate decarboxylase |
|
Genes |
» show all
|
Reference |
1 |
Authors |
Hill, R.K., Sawada, S. and Arfin, S.M. |
Title |
Stereochemistry of valine and isoleucine biosynthesis. IV. Synthesis, configuration, and enzymatic specificity of alpha-acetolactate and alpha-aceto-alpha-hydroxybutyrate. |
Journal |
Bioorg Chem 8:175-189 (1979) |
Reference |
|
Authors |
Stormer FC. |
Title |
Isolation of crystalline pH 6 acetolactate-forming enzyme from Aerobacter aerogenes. |
Journal |
J Biol Chem 242:1756-9 (1967) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.5 |
ExPASy - ENZYME nomenclature database: | 4.1.1.5 |
BRENDA, the Enzyme Database: | 4.1.1.5 |
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