KEGG   ENZYME: 4.1.1.64
Entry
EC 4.1.1.64                 Enzyme                                 
Name
2,2-dialkylglycine decarboxylase (pyruvate);
dialkyl amino acid (pyruvate) decarboxylase;
alpha-dialkyl amino acid transaminase;
2,2-dialkyl-2-amino acid-pyruvate aminotransferase;
L-alanine-alpha-ketobutyrate aminotransferase;
dialkylamino-acid decarboxylase (pyruvate);
2,2-dialkylglycine carboxy-lyase (amino-transferring)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)
Reaction(IUBMB)
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine [RN:R03854]
Reaction(KEGG)
R03854
Substrate
2,2-dialkylglycine [CPD:C02623];
pyruvate [CPD:C00022]
Product
dialkyl ketone [CPD:C02146];
CO2 [CPD:C00011];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein. Acts on 2-amino-2-methylpropanoate (i.e. 2-methylalanine), 2-amino-2-methylbutanoate and 1-aminocyclopentanecarboxylate.
History
EC 4.1.1.64 created 1972
Orthology
K00596  2,2-dialkylglycine decarboxylase (pyruvate)
Genes
PSEJHNQ25_01760
PTYJWV26_09800
HAAA5892_06680 A5892_07480
BVIBcep1808_3365
BVEAK36_3396(dgdA)
BURBcep18194_B0665
BCMBcenmc03_5282
BCHBcen2424_5005
BCJBCAM2237
BCENDM39_5613(dgdA)
BCEWDM40_4955(dgdA)
BCEOI35_6128
BAMBamb_4418
BACBamMC406_4936
BCTGEM_3432
BCEDDM42_5757(dgdA)
BCEPAPZ15_27875
BPYRABD05_24335
BCONNL30_01295
BDFWI26_24005
BLATWK25_27250
BTEIWS51_08310
BSEMWJ12_31120
BPSLWS57_02965
BSTLBBJ41_24910
BANNJFN94_29095
BGDbgla_2g24020
BGOBM43_6089(dgdA)
BYIBYI23_C012020
BUKMYA_2984
BUEBRPE67_CCDS14570
BGPBGL_2c24400
BPLAbpln_2g24710
BUMAXG89_34715
BUIAX768_17785
BURKDM992_22680
BXEBxe_B2675
BXBDR64_5009(dgdA)
BPYBphyt_2046
BFNOI25_5730(dgdA)
BCAIK788_0007088
PARBCJU94_26030
PHSC2L64_34830
PTERC2L65_30880
PMEGFNZ07_09915
PACPFAZ97_32620
PACSFAZ98_26545
PEWKZJ38_32105
PDIOPDMSB3_0378.1(dgdA)
PPKU875_11315
PPNODA70_03710
PPNMLV28_02605
PRBX636_23390
PPULRO07_21545
PSPUNA29_15775
PAPISG18_20380
PVEUC34_12750
POXMB84_17190
PFGAB870_22935
PNRAT302_19615
PANDDRB87_11865
PFIBPI93_015195
PCOMNTU39_14255
CABASBC2_41840(dgdA)
BUOBRPE64_DCDS08220
BBROBAU06_24640
BOHAKI39_23510
AXYAXYL_05358(dgdA)
AXONH44784_032131
AXNAX27061_5147
AXXERS451415_05181(dgdA_2)
AISBUW96_15430
RHYRD110_08995
VPEVarpa_4653
VBOCKY39_32625
ADNAlide_3099
ADKAlide2_1348
MPTMpe_A1466
METPC1M51_00890
RGERGE_11320
RBNRBXJA2T_07210
MIUABE85_09735
IDCLRM40_16635
HEEhmeg3_01805
AAKAA2016_4777
SMDSmed_5089
ATUAtu5302
ATAAWN88_04245
AROB0909_23225
AGTEYD00_20445
RIRBN877_II1367(dgdA)
RPUSCFBP5875_20670
RHVBA939_19280
NENNCHU2750_08140(dgdA)
SHZshn_26760
ABAWD5400_02300
BRKCWS35_02565
BELBE61_15160
BSEPHAP48_0019430
BQBJ4P68_0022940
BOPAXW83_13185 AXW83_15800 AXW83_15845
BVVBHK69_15960
BOIBLM15_17870
LNEFZC33_01075
APOLK9D25_09310
MRDMrad2831_2878
MORMOC_3244
MPHYMCBMB27_02318
METXA3862_17405
MMESMMSR116_13325
MTADM6G65_16925
CMETK6K41_26165
AALAIGS74_18190
AALMLUX29_20210
NOHG5V57_27625
LAPACP90_01925
LABTFIU93_07530(dgdA)
LAGGB0E33_13415
PABYGa0080574_TMP3290
SPSESULPSESMR1_01214(dgdA)
RMMROSMUCSMR3_03320(dgdA)
ROKRAK1035_2212
PSHQF3W81_00480
PPAFI8N54_04740
SSANNX02_17365
GXLH845_1622
SHUMSTHU_11310
SVCSTVA_06260 STVA_10640 STVA_11840
STELSTAQ_33140 STAQ_39370
TMOTMO_1799(dgdA)
TXITH3_07410
THACCSC3H3_22560
TIIDY252_10290
THAIIT893_10990
LMELEUM_0839
LMMMI1_03880
LMKLMES_0762
AMICAmi3637_05655
MGOAFA91_06220
MSMMSMEG_6842
MSGMSMEI_6659
MSBLJ00_33805
MSNLI99_33810
MSHLI98_33815
MVAMvan_5803
MAUUNCTC10437_05573(dgdA_2)
MMAGMMAD_03210
MTYMTOK_18920
MARZMARA_53390
MPOFMPOR_03910
NTPCRH09_35075
NOZDMB37_15305
NAHF5544_35585
NIEKV110_35680
GPOGPOL_c48070
GRUGCWB2_22815(dgdA)
GOMD7316_03141(dgdA)
GAVC5O27_05595
GJIH1R19_21970
GOILK459_13435
GMGNWF22_12005
TPRTpau_3251
TSMASU32_05225
TPULTPB0596_10460
SCOSCO7537(SC8G12.13c)
SVLStrvi_5938
SRCM271_42620
SMALSMALA_0919
SSOII1A49_08085
SLVSLIV_01625(dgdA)
SPAVSpa2297_01110
STRDNI25_35870
SNWBBN63_01490
SAUOBV401_08395
SSIAA7J05_02840
SALFSMD44_08818
SBYH7H31_03340
SPACB1H29_35105
SCHACP983_39355
SSPBCP982_39640
SDWK7C20_36570
SGJIAG43_00340
SMAOCAG99_08730
SAOVG3H79_00575
SDURM4V62_01435
AARCG127AT_12160
LMOIVV02_24205
CETB8281_16675
CCEUCBR64_14670
SERJSGUI_1980
NOYEXE57_06905
NROK8W59_02750
SROSros_5114
NOWGBF35_29485
NGNLCN96_50290
NMLNamu_5409
NAKEH165_08795
SENSACE_2647
SACGFDZ84_27200
AMDAMED_0279
AMNRAM_01410
AMMAMES_0274
AMZB737_0275
AOIAORI_6411
AJAAJAP_06860(dgdA)
AMYCCU254_08120
AMYBBKN51_25485
AABA4R43_00605
AMYYYIM_34545(dgdA)
AORISD37_08345 SD37_09450
APRTMUY14_35140
AROONQK81_33770
PDXPsed_5588
PSEEFRP1_10245
PSEQAD006_17795
PECQAD017_25630
PHHAFB00_25355
PAUTPdca_37220
APRECNX65_23970
AMIAmir_4825
SSYIEKG83_20325
KALKALB_5707
KPHYAOZ06_23470
LEDBBK82_38655
AHMTL08_05550
ACTIUA75_05470
ACADUA74_05470
AHGAHOG_05110(dgdA)
ACTAC1701_00110
PMADBAY61_18000
MCRAID554_29930
ACTNL083_6648
AFSAFR_23730
AIHAiant_90830
PSUUPsuf_076290
VERHUT12_15125
PRYPrubr_72730
CATICS0771_63520
DVCDvina_09800
DFUDfulv_09165
DAURDaura_09180
SNASnas_1896
BTPD805_0368
BSUEBS3272_00700
EKEEK0264_00290
SBAEDSM104329_03124(dgdA)
KBSEPA93_24995
 » show all
Reference
1
  Authors
Bailey, G.B. and Dempsey, W.B.
  Title
Purification and properties of an alpha-dialkyl amino acid transaminase.
  Journal
Biochemistry 6:1526-1533 (1967)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.64
IUBMB Enzyme Nomenclature: 4.1.1.64
ExPASy - ENZYME nomenclature database: 4.1.1.64
BRENDA, the Enzyme Database: 4.1.1.64
CAS: 9032-17-1

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