KEGG   ENZYME: 4.1.1.68
Entry
EC 4.1.1.68                 Enzyme                                 
Name
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase;
5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase;
5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase;
5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
(3E,5R)-5-carboxy-2-oxohept-3-enedioate carboxy-lyase [(4Z)-2-oxohept-4-enedioate-forming]
Reaction(IUBMB)
(3E,5R)-5-carboxy-2-oxohept-3-enedioate = (4Z)-2-oxohept-4-enedioate + CO2 (overall reaction) [RN:R04133];
(1a) (3E,5R)-5-carboxy-2-oxohept-3-enedioate = (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate + CO2;
(1b) (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate = (4Z)-2-oxohept-4-enedioate
Reaction(KEGG)
R04133;
(other) R04380
Substrate
(3E,5R)-5-carboxy-2-oxohept-3-enedioate;
(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate
Product
(4Z)-2-oxohept-4-enedioate;
CO2 [CPD:C00011];
(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate
Comment
Requires Mg2+ [2,3]. Part of the 4-hydroxyphenylacetate degradation pathway in Escherichia coli.
History
EC 4.1.1.68 created 1984
Pathway
ec00350  Tyrosine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05921  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
Genes
EOI: ECO111_5214(hpcE)
EOJ: ECO26_5557(hpcE)
EOH: ECO103_5136(hpcE)
ECOO: ECRM13514_5608
ECOH: ECRM13516_5322
ECOA: APECO78_02920
ECX: EcHS_A4584(hpaG)
ECY: ECSE_4629
ECR: ECIAI1_4575(hpaG)
EUM: ECUMN_4975(hpaG)
EBR: ECB_04230(hpaG)
EBL: ECD_04230(hpaG)
EBE: B21_04196(ybl228)
EBD: ECBD_3666
ECL: EcolC_3702
EKO: EKO11_3960
EKF: KO11_23405(hpaG)
ELW: ECW_m4713(hpaG)
ELL: WFL_22960(hpaG)
ECOL: LY180_22840
EFE: EFER_3062(hpaG)
STY: STY1134(hpaG)
STT: t1818(hpaG)
SEX: STBHUCCB_19340
SENT: TY21A_09255
STM: STM1101(hpaG)
SEO: STM14_1250(hpaG)
SEV: STMMW_11111
SEY: SL1344_1040(hpaG)
SEM: STMDT12_C11200
SEJ: STMUK_1070(hpaG)
SEB: STM474_1093(hpaG)
SEF: UMN798_1143(hpaG)
SETU: STU288_01835
SETC: CFSAN001921_11670
SENR: STMDT2_10371(hpaG)
SEND: DT104_10831(hpaG)
SENI: CY43_05625
SEEN: SE451236_11355
SPQ: SPAB_02452
SEI: SPC_2649(hpaG)
SEC: SCH_1051(hpaG)
SEH: SeHA_C1211
SHB: SU5_01732
SENH: CFSAN002069_03515
SEEH: SEEH1578_14730
SEE: SNSL254_A1196
SENN: SN31241_21680
SEW: SeSA_A1165
SEA: SeAg_B1060
SENS: Q786_04920
SED: SeD_A1176
SEG: SG0990(hpaG)
SEL: SPUL_1956(hpaG)
SEGA: SPUCDC_1942(hpaG)
SET: SEN0965(hpaG)
SENA: AU38_04980
SENO: AU37_04970
SENV: AU39_04970
SENQ: AU40_05585
SENL: IY59_05070
SENJ: CFSAN001992_06140
SEEC: CFSAN002050_11900
SEEB: SEEB0189_014065
SEEP: I137_08890
SENB: BN855_10560(hpaG)
SENE: IA1_05420
SENC: SEET0819_12165
SES: SARI_01901
SBG: SBG_0947(hpaG)
SBZ: A464_1041
SALZ: EOS98_14110
SFL: SF4384(hpaG)
SFX: S4654(hpaG)
SFV: SFV_4384(hpaG)
SFE: SFxv_4778
SFN: SFy_6292
SFS: SFyv_6362
SFT: NCTC1_04760(hpaG)
SSN: SSON_4499(hpaG)
SBO: SBO_4412(hpaG)
SBC: SbBS512_E4890(hpaG)
SHQ: A0259_03545
ENC: ECL_00758
ENL: A3UG_03040
ECLG: EC036_05950
ECLE: ECNIH2_03940
ECLN: ECNIH4_19860
ECLI: ECNIH5_03065
ECLX: LI66_03060
ECLY: LI62_03530
ECLZ: LI64_03035
ECLO: ENC_44720
EHM: AB284_21945
EXF: BFV63_03015
ECLA: ECNIH3_03065
ECLC: ECR091_03045
EAU: DI57_15580
EKB: BFV64_02680
ENO: ECENHK_03135
EEC: EcWSU1_00557(hpaG)
ELG: BH714_17665
ECAN: CWI88_19255
ERN: BFV67_02850
ECLS: LI67_003995
ECHG: FY206_03570
ESH: C1N69_02900
EAS: Entas_0536
ENX: NI40_002905
LNI: CWR52_09205
EBG: FAI37_03645
ENZ: G0034_02930
ENS: HWQ15_11470
ENK: LOC22_13810
EHU: D5067_0019995
EMOR: L6Y89_02840
ENB: ELK40_03630
KPN: KPN_04788(hpaG) KPN_04789(hpaG)
KPU: KP1_0742(hpaG2) KP1_0743(hpaG1)
KPM: KPHS_06340 KPHS_06350
KPP: A79E_4363 A79E_4364
KPH: KPNIH24_03265 KPNIH24_03270
KPZ: KPNIH27_03140 KPNIH27_03145
KPV: KPNIH29_03455 KPNIH29_03460
KPW: KPNIH30_03415 KPNIH30_03420
KPY: KPNIH31_04645 KPNIH31_04650
KPG: KPNIH32_03420 KPNIH32_03425
KPC: KPNIH10_03245 KPNIH10_03250
KPQ: KPR0928_03255 KPR0928_03260
KPT: VK055_2650(hpaG) VK055_2651
KPO: KPN2242_02075 KPN2242_02080
KPR: KPR_0867(hpaG2) KPR_0868(hpaG)
KPJ: N559_4507 N559_4508
KPI: D364_24395 D364_24400
KPA: KPNJ1_04823 KPNJ1_04824
KPS: KPNJ2_04771 KPNJ2_04772
KPX: PMK1_02247(hpcE_1) PMK1_02248(hpcE_2)
KPB: FH42_20460 FH42_20465
KPNE: KU54_023325 KU54_023330
KPNU: LI86_23165 LI86_23170
KPNK: BN49_4405(hpaG) BN49_4406(hpaG2)
KVA: Kvar_4463 Kvar_4464
KPE: KPK_4831 KPK_4832
KPK: A593_13995 A593_14000
KVD: KR75_11445 KR75_11450
KVQ: SP68_18080 SP68_18085
KOX: KOX_10055 KOX_10060
KOE: A225_0713 A225_0714
KOY: J415_27675 J415_27680
KOM: HR38_08780 HR38_08785
KOK: KONIH1_03780 KONIH1_03785
KOC: AB185_32405 AB185_32410
KQU: AVR78_07790 AVR78_07795
EAE: EAE_10355 EAE_10360
EAR: CCG31923 CCG31924
KQV: B8P98_24195 B8P98_24200
KLL: BJF97_04330 BJF97_04335
KLW: DA718_24745 DA718_24750
KAR: LGL98_21800 LGL98_21805
KGR: JJJ10_24210 JJJ10_24215
KPAS: LUW96_10320 LUW96_10325
ROR: RORB6_15520 RORB6_15525
RON: TE10_05495 TE10_05500
RPLN: B1209_23480 B1209_23485
RAO: DSD31_22235 DSD31_22240
RTG: NCTC13098_06415(hpcE_1) NCTC13098_06416(hpcE_2)
REE: electrica_04371(hpcE_1) electrica_04372(hpcE_2)
CBRA: A6J81_18545 A6J81_18550
EBT: EBL_c33950(hpcE) EBL_c33960(hpaG)
PGE: LG71_25455
ESC: Entcl_3797
KLE: AO703_02930
KIE: NCTC12125_02702(hpcE_1) NCTC12125_02703(hpcE_2)
KAS: KATP_35240
KLU: K7B04_10625
LAX: APT61_19305
LEI: C2U54_08015
LEH: C3F35_08675
LEE: DVA44_20810
LER: GNG29_03260
LEA: GNG26_02815
LPNU: KQ929_17865
BUF: D8682_01725 D8682_01730
BFT: MNO13_13765 MNO13_13770
YRE: HEC60_20825
IZH: FEM41_12635
PSGC: G163CM_29740(hpcE)
EBF: D782_3919
EBU: CUC76_12045
YPH: YPC_2520 YPC_2521
YPA: YPA_1133 YPA_1134
YPN: YPN_2361 YPN_2362
YPP: YPDSF_1361 YPDSF_1362
YPZ: YPZ3_1956 YPZ3_1957
YPT: A1122_17055 A1122_17060
YPD: YPD4_1559 YPD4_1560
YPX: YPD8_1994 YPD8_1995
YPW: CH59_3405(hpaG) CH59_3406(hpaG)
YPJ: CH55_916(hpaG) CH55_917(hpaG)
YPV: BZ15_1787(hpaG) BZ15_1788(hpaG)
YPL: CH46_3361(hpaG) CH46_3362(hpaG)
YPS: YPTB1637(hpaG) YPTB1638
YPO: BZ17_864(hpaG) BZ17_865(hpaG)
YPI: YpsIP31758_2364(hpaG2) YpsIP31758_2365(hpaG1)
YPY: YPK_2460 YPK_2461
YPB: YPTS_1761 YPTS_1762
YPQ: DJ40_585(hpaG) DJ40_586(hpaG)
YPU: BZ21_987(hpaG) BZ21_988(hpaG)
YPR: BZ20_337(hpaG) BZ20_338(hpaG)
YPC: BZ23_1265(hpaG) BZ23_1266(hpaG)
YPF: BZ19_1064(hpaG) BZ19_1065(hpaG)
SMAR: SM39_4958(hpcE1) SM39_4959(hpcE2)
SMAC: SMDB11_4701(hpcE1) SMDB11_4702(hpcE2)
SMW: SMWW4_v1c05810 SMWW4_v1c05820
SPE: Spro_0625 Spro_0626
SRR: SerAS9_0561 SerAS9_0562
SRL: SOD_c04930(hpaG1) SOD_c04940(hpaG)
SRY: M621_02605 M621_02610
SPLY: Q5A_002595(hpcE_1) Q5A_002600(hpcE_2)
SRS: SerAS12_0561 SerAS12_0562
SRA: SerAS13_0561 SerAS13_0562
SMAF: D781_0569 D781_0570
SLQ: M495_02470 M495_02475
SERF: L085_01190 L085_01195
SERS: SERRSCBI_02745 SERRSCBI_02750
SFW: WN53_11465 WN53_11470
SFG: AV650_06750 AV650_06755
SRZ: AXX16_4538 AXX16_4539
SERM: CLM71_02755 CLM71_02760
SQU: E4343_13525 E4343_13530
SFJ: SAMEA4384070_0652(hpcE_1) SAMEA4384070_0653(hpcE_2)
SOF: NCTC11214_00932(hpcE_1) NCTC11214_00933(hpcE_2)
SSUR: ATE40_023585 ATE40_023590
SURI: J0X03_21075 J0X03_21080
SRHZ: FO014_07080 FO014_07085
SENP: KHA73_02640 KHA73_02645
SNEM: NLX84_02785 NLX84_02790
SFO: Z042_16795 Z042_16800
EPE: CI789_23885
PLU: plu0989(hpaG2) plu0990(hpaG1)
PLUM: A4R40_04945 A4R40_04950
PAY: PAU_00932(hpaG2) PAU_00933(hpaG1)
PTT: VY86_12505 VY86_12510
PAKH: B0X70_05375 B0X70_05380
PLUI: CE143_05305 CE143_05310
XBO: XBJ1_0866 XBJ1_0867
XBV: XBW1_1478(hpaG) XBW1_1479
XNE: XNC1_0822 XNC1_0823
XNM: XNC2_0807 XNC2_0808
XDO: XDD1_1025(hpaG2) XDD1_1026(hpaG1)
XHO: A9255_20610 A9255_20615
XBU: HGO23_05375 HGO23_05380
PSI: S70_06425 S70_06430
PSX: DR96_1982(hpaG) DR96_1983(hpaG)
PSTA: BGK56_09465 BGK56_09470
PRG: RB151_008130(hpcE_1) RB151_008140(hpcE_2)
PALA: CO695_00740 CO695_00745
PHEI: NCTC12003_00826(hpcE_1) NCTC12003_00827(hpcE_2)
PRQ: CYG50_11465 CYG50_11470
PRJ: NCTC6933_00884(hpcE_1) NCTC6933_00885(hpcE_2)
PVC: G3341_03910 G3341_03915
PMAG: JI723_04370 JI723_04375
MWI: MNY66_12690
ETE: ETEE_3251(hpaG) ETEE_3252(hpaG)
EDW: QY76_13795 QY76_13800
EDL: AAZ33_06655 AAZ33_06660
HAV: AT03_16910 AT03_16915
HPAR: AL518_09740 AL518_09745
OPO: DSM2777_08310 DSM2777_08315
PFQ: QQ39_14455 QQ39_14460
PRAG: EKN56_03330 EKN56_03335
PMU: PM1528(hpaG_1) PM1529(hpaG_2)
PMV: PMCN06_1795(hpaG1) PMCN06_1796(hpaG2)
PUL: NT08PM_1855 NT08PM_1856
PMP: Pmu_17950(hpaG1) Pmu_17960(hpaG2)
PMUL: DR93_377(hpaG) DR93_378(hpaG)
PCAI: K7G93_001652 K7G93_001653
FAU: Fraau_1724 Fraau_1725
VVY: VV1583 VV1584
VNI: VIBNI_B1954 VIBNI_B1955
VSI: MTO69_16170 MTO69_16175
VMI: AL543_16430 AL543_16435
PAE: PA4121 PA4122
PAEV: N297_4253(hpaG) N297_4254(hpaG)
PAEI: N296_4253(hpaG) N296_4254(hpaG)
PAU: PA14_10640(hpaG2) PA14_10650(hpaG1)
PAP: PSPA7_0970 PSPA7_0971
PAG: PLES_08491 PLES_08501
PAF: PAM18_0817 PAM18_0818
PNC: NCGM2_5322(hpaG1) NCGM2_5323(hpaG2)
PAEB: NCGM1900_0838(hpaG2) NCGM1900_0839(hpaG1)
PSG: G655_04090 G655_04095
PRP: M062_21735 M062_21740
PAEP: PA1S_04210 PA1S_04215
PAER: PA1R_gp2012 PA1R_gp2013
PAEM: U769_04235 U769_04240
PAEL: T223_04145 T223_04150
PAES: SCV20265_0845 SCV20265_0846
PAEU: BN889_04575 BN889_04576
PAEG: AI22_29400 AI22_29405
PAEC: M802_4251(hpaG) M802_4252(hpaG)
PAEO: M801_4119(hpaG) M801_4120(hpaG)
PRE: PCA10_16340(hpaG2) PCA10_16350(hpaG1)
PFUW: KF707C_32020 KF707C_32030
PCQ: PcP3B5_43380(hpcE_1) PcP3B5_43390(hpcE_2)
PPAA: B7D75_04080 B7D75_04085
PPG: PputGB1_3496 PputGB1_3497
PPUN: PP4_18990(hpaG2) PP4_19000(hpaG1)
PMOS: O165_009150 O165_009155
PMOL: CLJ08_25220 CLJ08_25225
PFL: PFL_3370(hpaG_1) PFL_3371(hpaG_2)
PPRC: PFLCHA0_c34000(hpaG1) PFLCHA0_c34010(hpaG2)
PPRO: PPC_3394(hpaG_1) PPC_3395
PFE: PSF113_2550 PSF113_2551
PFN: HZ99_06960 HZ99_06965
PFS: PFLU_3269 PFLU_3270
PFC: PflA506_3394(hpaG_1) PflA506_3395(hpaG_2)
PFB: VO64_1095 VO64_1096
PTV: AA957_24925 AA957_24930
PCG: AXG94_00030 AXG94_00035
PAZO: AYR47_26775 AYR47_26780
PMED: E3Z27_12230 E3Z27_12235
PFW: PF1751_v1c34780(hpaG) PF1751_v1c34790(hpaG)
PFF: PFLUOLIPICF718510 PFLUOLIPICF718515
PEN: PSEEN3092(hpaG-1) PSEEN3093(hpaG-2)
PLUL: FOB45_04655 FOB45_04660
PBA: PSEBR_a2743 PSEBR_a2744
PBC: CD58_13845 CD58_13850
PDR: H681_09015 H681_09020
PSK: U771_17275 U771_17280
PKC: PKB_2458(hpaG) PKB_2459
PCH: EY04_16730 EY04_16735
PCZ: PCL1606_27020 PCL1606_27030
PCP: JM49_14000 JM49_14005
PSW: LK03_18015 LK03_18020
PSES: PSCI_3411 PSCI_3412
PSEM: TO66_17385 TO66_17390
PSEC: CCOS191_2707(hpaG1) CCOS191_2708(hpaG2)
PSOS: POS17_3351(hpaG_1) POS17_3352
PANR: A7J50_3678 A7J50_3679
PSET: THL1_2752 THL1_2753
PYM: AK972_3748 AK972_3749
POJ: PtoMrB4_16790 PtoMrB4_16800
PVK: EPZ47_13775 EPZ47_13780
PEZ: HWQ56_10205 HWQ56_10210
PBZ: GN234_04530 GN234_04535
PKH: JLK41_06115 JLK41_06120
PDW: BV82_3347 BV82_3348
PSEP: C4K39_5339 C4K39_5340
PVW: HU752_019655 HU752_019660
PTRT: HU722_0018750 HU722_0018755
PSAM: HU731_005385 HU731_005390
PQI: KH389_12140 KH389_12145
PSHH: HU773_017835 HU773_017840
PXN: HU772_013365 HU772_013370
PPRG: HU725_013735 HU725_013740
PASG: KSS96_11970 KSS96_11975
PMUY: KSS95_15015 KSS95_15020
PMAM: KSS90_12435 KSS90_12440
PORY: EJA05_13170 EJA05_13175
PTK: EXN22_12280 EXN22_12285
PTW: TUM18999_28840 TUM18999_28850
PZA: HU749_016605 HU749_016610
PSIH: LOY51_12990 LOY51_12995
PCAS: LOY40_17105 LOY40_17110
EMO: DM558_04935 DM558_04940
EAZ: JHT90_12405 JHT90_12410
MSQ: BKP64_00775 BKP64_00780
ABAZ: P795_8015 P795_8020
ABK: LX00_09745 LX00_09750
ABAU: IX87_20485 IX87_20490
ABOU: ACBO_11640 ACBO_11650
ACIU: A3K93_02895 A3K93_02900
ADI: B5T_01361 B5T_01362 B5T_03291 B5T_03292
AXE: P40_15415 P40_15420
MMW: Mmwyl1_3176 Mmwyl1_3177
MPRI: MP3633_3049 MP3633_3050
MRHI: KDW99_14225 KDW99_14230
MGEO: CFI10_04480 CFI10_04485
MSEC: LN244_12200 LN244_12205
MARL: HH196_02935
NJP: NEJAP_1966 NEJAP_1967
AJP: AMJAP_1984 AMJAP_1985
IGN: MMG00_10975 MMG00_10980
VFF: VITFI_CDS3299 VITFI_CDS3300
CRZ: D1345_13720 D1345_13725
CHAE: CH06BL_29030 CH06BL_29040
AQL: BXU06_01530 BXU06_01535
AMAH: DLM_0617 DLM_0618
AQS: DKK66_02100 DKK66_02105
RPI: Rpic_1959 Rpic_1960
RPF: Rpic12D_1631 Rpic12D_1632
RMN: TK49_12430 TK49_12435
RIN: ACS15_1519 ACS15_1520
RWE: KOL96_16030 KOL96_16035
CBW: RR42_s1465 RR42_s1466
CCUP: BKK81_27570 BKK81_27575
CUP: BKK80_28750 BKK80_28755
CUU: BKK79_34700 BKK79_34705
BMA: BMAA1139 BMAA1140
BML: BMA10229_0100 BMA10229_0101
BMN: BMA10247_A1512 BMA10247_A1513
BMAL: DM55_4408(hpaG) DM55_4409(hpaG)
BMAE: DM78_3450(hpaG) DM78_3451(hpaG)
BMAQ: DM76_3358(hpaG) DM76_3359(hpaG)
BMAI: DM57_09675 DM57_09680
BMAF: DM51_4808(hpaG) DM51_4809(hpaG)
BMAZ: BM44_4561(hpaG) BM44_4562(hpaG)
BMAB: BM45_3686(hpaG) BM45_3687(hpaG)
BPS: BPSS0692 BPSS0693
BPM: BURPS1710b_A2263(hpaG) BURPS1710b_A2264(hpaG)
BPL: BURPS1106A_A0938 BURPS1106A_A0939
BPD: BURPS668_A1023 BURPS668_A1024
BPSE: BDL_3923(hpaG) BDL_3924(hpaG)
BPZ: BP1026B_II0765 BP1026B_II0766
BPK: BBK_3797(hpaG) BBK_3798(hpaG)
BPSH: DR55_4657(hpaG) DR55_4658(hpaG)
BPSA: BBU_5349(hpaG) BBU_5350(hpaG)
BPSO: X996_3875(hpaG) X996_3876(hpaG)
BUT: X994_3923(hpaG) X994_3924(hpaG)
BTE: BTH_II1734(hpaG-1) BTH_II1735(hpaG-2)
BTV: BTHA_5720(hpaG) BTHA_5721(hpaG)
BTHE: BTN_4147(hpaG) BTN_4148(hpaG)
BTHM: BTRA_3945(hpaG) BTRA_3946(hpaG)
BTHA: DR62_4182 DR62_4183
BTHL: BG87_4478(hpaG) BG87_4479(hpaG)
BOK: DM82_4771(hpaG) DM82_4772(hpaG)
BOC: BG90_5821(hpaG) BG90_5822(hpaG)
BUU: WS70_20785 WS70_20790
BSAV: WS86_22075 WS86_22080
BHG: I6G56_24635 I6G56_24640
BVI: Bcep1808_4801 Bcep1808_4802
BVE: AK36_4116(hpaG) AK36_4117
BUR: Bcep18194_B1782 Bcep18194_B1783
BCM: Bcenmc03_3285 Bcenmc03_3286
BCH: Bcen2424_4231 Bcen2424_4232
BCJ: BCAM1366(hpaG) BCAM1367(hpaG')
BCEN: DM39_3638(hpaG) DM39_3639(hpaG)
BCEW: DM40_4255(hpaG) DM40_4256(hpaG)
BCEO: I35_5218(hpaG) I35_5219(hpaG')
BAM: Bamb_3653 Bamb_3654
BAC: BamMC406_4127 BamMC406_4128
BMU: Bmul_4373 Bmul_4374
BMK: DM80_3536(hpaG) DM80_3537(hpaG)
BMUL: NP80_4258(hpaG) NP80_4259(hpaG)
BCT: GEM_4388 GEM_4389
BCED: DM42_3720(hpaG) DM42_3721(hpaG)
BCEP: APZ15_17830 APZ15_17835
BDL: AK34_4141(hpaG) AK34_4142(hpaG)
BPYR: ABD05_29365 ABD05_29370
BCON: NL30_05825 NL30_05830
BUB: BW23_5043(hpaG) BW23_5044(hpaG)
BDF: WI26_19825 WI26_19830
BLAT: WK25_23640 WK25_23645
BTEI: WS51_04520 WS51_04525
BSEM: WJ12_26630 WJ12_26635
BPSL: WS57_07260 WS57_07265
BMEC: WJ16_25220 WJ16_25225
BSTG: WT74_25590 WT74_25595
BSTL: BBJ41_19870 BBJ41_19875
BARI: NLX30_31765 NLX30_31770
BUG: BC1001_5335 BC1001_5336
BGF: BC1003_4085 BC1003_4086
BUK: MYA_4420
BUL: BW21_5182(hpaG) BW21_5183(hpaG)
BUQ: AC233_10975 AC233_23390 AC233_23395
BUD: AQ610_27300 AQ610_27305
BURK: DM992_19110 DM992_19115
BXE: Bxe_B2028 Bxe_B2029
BXB: DR64_7330 DR64_7331(hpaG)
BGE: BC1002_3575 BC1002_3576
BPX: BUPH_05747 BUPH_05748
BPY: Bphyt_5824 Bphyt_5825
BUZ: AYM40_23790 AYM40_23795
BFN: OI25_4430 OI25_4431(hpaG)
BCAI: K788_0007889 K788_0007890
PARB: CJU94_20035 CJU94_20040
PHS: C2L64_36765 C2L64_36770
PTER: C2L65_32255 C2L65_32260
PGP: CUJ91_20150 CUJ91_20155
PCJ: CUJ87_18055 CUJ87_18060
PTS: CUJ90_27700 CUJ90_27705
PCAF: DSC91_001880 DSC91_001881
PMEG: FNZ07_23060 FNZ07_23065
PTRO: G5S35_21205 G5S35_21210
PGIS: I6I06_20120 I6I06_20125
PACP: FAZ97_23285 FAZ97_23290
PACS: FAZ98_18680 FAZ98_18685
PDIO: PDMSB3_1098.1 PDMSB3_1099.1
PBRY: NDK50_31165 NDK50_31170
BRH: RBRH_00354 RBRH_00355
PPK: U875_00140
PPNO: DA70_17770
PPNM: LV28_13025
PRB: X636_09125
PPUL: RO07_06985
PSPU: NA29_02875
PAPI: SG18_07385
PVE: UC34_23075
POX: MB84_03025
PTX: ABW99_06770 ABW99_06775
PFG: AB870_09950
PNR: AT302_06590
PAND: DRB87_21495
PFIB: PI93_004945
PCOM: NTU39_25215
HYF: DTO96_101731(hpcE_1) DTO96_101732(hpcE_2)
BPAR: BN117_0692(hpaG) BN117_0693
BBH: BN112_2700 BN112_2701(hpaG)
BBR: BB0734(hpaG) BB0735
BBM: BN115_0708(hpaG) BN115_0709
BBX: BBS798_0712(hpaG) BBS798_0713
BAV: BAV1264(hpaG') BAV1265(hpaG)
BGM: CAL15_06610 CAL15_06615
BOJ: CBF45_15795 CBF45_15800
AXY: AXYL_04173 AXYL_04174
AXO: NH44784_056751 NH44784_056761
AXN: AX27061_3933 AX27061_3934
AXX: ERS451415_03956(hpcE_1) ERS451415_03957(hpcE_2)
ADT: APT56_18385 APT56_18390
AIS: BUW96_10100 BUW96_10105
ASW: CVS48_22595 CVS48_22600
ACHR: C2U31_24570 C2U31_24575
ACHB: DVB37_16875 DVB37_16880
ADY: HLG70_03115 HLG70_03120
AMIM: MIM_c17570(hpaG1) MIM_c17580(hpaG2)
CDN: BN940_16381 BN940_16386
KGY: EHF36_15845 EHF36_15850
PARK: LSG25_15100 LSG25_15105
RHF: EUB48_20500 EUB48_20505
AAA: Acav_3015
DAC: Daci_0107 Daci_0108
DEL: DelCs14_0109 DelCs14_0110
DTS: BI380_22280 BI380_22285
DHK: BO996_02450 BO996_02455
DLA: I6G47_22230 I6G47_22235
VAP: Vapar_0244 Vapar_0245
VPE: Varpa_0249 Varpa_0250
VPD: VAPA_1c02980 VAPA_1c02990 VAPA_1c22640 VAPA_1c22650
VBO: CKY39_01485 CKY39_01490
VAM: C4F17_17590 C4F17_17595
COF: FOZ74_10680 FOZ74_10685
CODO: LAD35_15650 LAD35_15655
RTA: Rta_01810 Rta_01820
RTEA: HK414_00995
OTK: C6570_01930 C6570_01935
LIM: L103DPR2_00424(hpcE_1) L103DPR2_00425(hpcE_2)
LIH: L63ED372_02764(hpcE_1) L63ED372_02765(hpcE_2)
HYR: BSY239_4290 BSY239_4291(hpaG)
HYB: Q5W_21325 Q5W_21330
HYL: LPB072_01775 LPB072_01780 LPB072_19535
HYC: E5678_16130 E5678_16135
HPSE: HPF_01680(hpcE1) HPF_01685(hpcE2)
HYN: F9K07_02245 F9K07_02250
HTN: KI616_01835 KI616_01840
HCZ: G9Q37_18480
DIH: G7047_25010 G7047_25015
DRG: H9K76_08025 H9K76_08030
KIA: G8A07_25155 G8A07_25160
QAU: KI612_13760 KI612_13765
AZR: CJ010_16660 CJ010_16665
ACOM: CEW83_16465 CEW83_16470
PLA: Plav_1788
DEA: FPZ08_15290
CAUL: KCG34_01805
NOR: FA702_19095
SWI: Swit_4308 Swit_4309
SECH: B18_03720 B18_03725
MAG: amb0806 amb0807
HTQ: FRZ44_17530
HADH: FRZ61_29610
BCY: Bcer98_0971 Bcer98_0972
BFD: NCTC4823_03855(hpcE_1) NCTC4823_03856(hpcE_2)
BBAD: K7T73_16275 K7T73_16280
BACO: OXB_3441 OXB_3442
BEO: BEH_12505 BEH_12510
PKS: IE339_14165 IE339_14170
BKO: CKF48_12840 CKF48_12845
OIH: OB2865 OB2866
GKA: GK3030 GK3031
GTE: GTCCBUS3UF5_33900 GTCCBUS3UF5_33910
GTK: GT3570_14780 GT3570_14785
GTM: GT3921_03970 GT3921_03975
GLI: GLN3_07905
BCAL: CWI35_12860 CWI35_12865
GTN: GTNG_2988 GTNG_2989
GYC: GYMC61_3109 GYMC61_3110
GYA: GYMC52_3136 GYMC52_3137
GCT: GC56T3_0473 GC56T3_0474
GMC: GY4MC1_0467 GY4MC1_0468
GGH: GHH_c31040(hpaG1) GHH_c31050(hpaG2)
GJF: M493_15785 M493_15790
GSE: GT50_06855 GT50_06860
GEJ: A0V43_13000 A0V43_13005
GZA: IC807_11275 IC807_11280
GTH: Geoth_0535 Geoth_0536
PTL: AOT13_00520 AOT13_00525
PTB: DER53_14655 DER53_14660
PCAL: BV455_02284(hpcE_1) BV455_02285(hpcE_2)
PARG: PspKH34_04500 PspKH34_04510
ANM: GFC28_1566(hpaG) GFC28_1567(hpaG)
AAMY: GFC30_1750
ANL: GFC29_61(hpaG) GFC29_62(hpaG)
AND: GRQ40_05065 GRQ40_05070
HHD: HBHAL_2376(hpaG1) HBHAL_2377(hpaG2)
HMN: HM131_18410 HM131_18415
HLI: HLI_19730 HLI_19735
VIG: BKP57_18450 BKP57_18455
VIL: CFK37_10935 CFK37_10940
VPN: A21D_03940(hpcE_1) A21D_03941(hpcE_2)
VPT: KBP50_11255 KBP50_11260
FPN: ABE65_007010
FAR: ABE41_008065
APAK: AP3564_00600 AP3564_00605
BSJ: UP17_15180 UP17_15185
BMUR: ABE28_014070 ABE28_014075
PFRI: L8956_15900 L8956_15905
PSYH: D0S48_01890 D0S48_01895
PSYO: PB01_19040 PB01_19045
RUE: DT065_14075 DT065_14080
POF: GS400_10250 GS400_10255
NMK: CHR53_10005 CHR53_10010
MSEM: GMB29_05705 GMB29_05710
BVJ: I5776_15175 I5776_15180
BOU: I5818_18870 I5818_18875
CTHU: HUR95_08540
FHL: OE105_04750 OE105_04755
FAF: OE104_06415 OE104_06420
HYI: K2M58_06390 K2M58_06395
PSOP: KP014_02190
PTHI: NDS46_23235 NDS46_23240
ANX: ACH33_14100
ASOC: CB4_02012(hpcE_1) CB4_02466(hpcE_2) CB4_02467(hpcE_3)
ATHE: K3F53_04810
AAC: Aaci_0337
AAD: TC41_0457(hpaG)
ACYC: JI721_10945 JI721_10950
BTS: Btus_1575
KYR: CVV65_08560
EFF: skT53_05540
SPSY: AZE41_13980 AZE41_13985
PANC: E2636_17190 E2636_17195
TMR: Tmar_1820
SAY: TPY_2464(hpaG)
SAP: Sulac_3218
STHR: BXT84_13335
MMC: Mmcs_2606
MKM: Mkms_2650
CAR: cauri_2501(hpaG)
CHN: A605_03330
CAZ: CARG_02965
CCG: CCASEI_13870
CEI: CEPID_11900(hpaG)
CTED: CTEST_00865
CSP: WM42_1477
CSTA: CSTAT_12885
CPHO: CPHO_12180
CFC: CFLV_12710
CSTR: CBE89_01305
CAMG: CAMM_12570
CMIN: NCTC10288_00048(odx)
CPEG: CPELA_07995(hpcE)
CGK: CGERO_03120(hpcE)
CPSO: CPPEL_08230(hpcE)
CPRP: I6I69_06100
COK: COCCU_13940(hpcE)
CCYC: SCMU_24600
NFA: NFA_27790
NFR: ERS450000_01316(hpcE)
NBR: O3I_022370
RHS: A3Q41_02967(hpcE)
GPO: GPOL_c33220(hpaG)
SCB: SCAB_9721
SVL: Strvi_5945
SHY: SHJG_1783
SHO: SHJGH_1548
SRC: M271_42585
STRT: A8713_00810 A8713_00870
SCLF: BB341_04915
SGS: AVL59_13470
STSI: A4E84_37270
SLS: SLINC_8209
SFK: KY5_2588c
SGE: DWG14_00343(hpcE)
SLK: SLUN_38555
SCYA: EJ357_37730
SKA: CP970_29685
SAQU: EJC51_43210
SBY: H7H31_00225 H7H31_00375
SCHA: CP983_05170
SBAT: G4Z16_05460
SFEU: IM697_27550
SROI: IAG44_38990
SINE: KI385_15810
SLF: JEQ17_41625
SDEC: L3078_40740
SDUR: M4V62_28365
SAKB: K1J60_02965 K1J60_42510
LEIF: HF024_06175
LSE: F1C12_06800 F1C12_09785
MTS: MTES_0674
MIM: AKG07_00130
MIP: AXH82_11160
MCW: A8L33_07020
MPAL: BO218_07715
MIH: BJP65_05165
MICR: BMW26_04690
MAUR: BOH66_13310
MHOS: CXR34_14345
MFOL: DXT68_04810
MOO: BWL13_01224(hpcE_1) BWL13_02301(hpcE_2)
MLV: CVS47_00665(hpcE)
MWA: E4K62_04365
MPRT: ET475_02110
MOY: CVS54_01108(hpcE_1)
MCAW: F6J84_11775
MLZ: F6J85_04145
MRN: K8F61_08655
MICS: C1N74_03240
MLIQ: NMQ05_05670
RPLA: A4Z71_05985
MVD: AWU67_11415
AGY: ATC03_14640
AGM: DCE93_10215
AGF: ET445_16275
CPHY: B5808_00950
AMIN: AUMI_10090
AUM: AURMO_01497
AUW: AURUGA1_01409(hpcE)
MALK: MalAC0309_2156
SALA: ESZ53_13900
HUM: DVJ78_01710
HUW: FPZ11_13360
PLAP: EAO79_07080
LEU: Leucomu_10285
LTR: EVS81_13565
LVI: G7068_04845
LINS: G7067_06750
LLUT: K1X41_14320
AGG: C1N71_04410
MANT: BHD05_13370
GLN: F1C58_04500
ARR: ARUE_c40620(hpaG)
ARM: ART_3194
ARL: AFL94_06495
ARE: AL755_14115
AAQ: AOC05_17490
ARW: MB46_07065
ARH: AHiyo8_37340
ARY: ATC04_11475
ARZ: AUT26_10015
ARU: ASPU41_04210
ARQ: BWQ92_08645
ARN: CGK93_21760
ARX: ARZXY2_1954
ACRY: AC20117_21420
ARTH: C3B78_18115
ARTP: E5206_11290
AAGI: NCTC2676_1_02908(hpcE)
AJG: KKR91_08325
ASUN: KG104_08610
APOA: J0916_16265
ARI: UM93_06770
AAU: AAur_3917 AAur_pTC20089
PUE: FV140_10290
PNV: JMY29_18945
ACH: Achl_3608
APN: Asphe3_34980
PSUL: AU252_22400
PSNI: NIBR502771_07020
PSEY: GU243_03860
AAI: AARI_13310
GAR: AOZ07_06925
GCR: GcLGCM259_1109
GLU: F0M17_06650
GPR: JQN66_06865
RSA: RSal33209_1507
KRH: KRH_22050
KFV: AS188_00920
KII: KocCE7_11975
KOD: HBK84_11860
KVR: CIB50_0000836(hpcE)
MLU: Mlut_19980
MICK: B1A86_00009910
RAMA: IDM48_07780
RKR: I6G21_04660
SATK: SA2016_2476
AUL: DCC27_010305
CIG: E7744_13795
BCV: Bcav_0869
BRZ: CFK38_04890
BSAU: DWV08_11475
DNI: HX89_01510
DAY: FV141_00675
DERM: H7F30_02210
XYL: ET495_05310
IVA: Isova_1677
CFI: Celf_2072
CELH: GXP71_06015
SERJ: SGUI_0718
ORZ: FNH13_15065
BLY: A2T55_04345
BLIN: BLSMQ_0804
BLUT: EW640_09465
BCAU: I6G59_07115
MIK: FOE78_02955
MICG: GJV80_01435
NARO: CFH99_04930
AGRA: AGRA3207_001813
SRO: Sros_7504 Sros_7522
NOW: GBF35_28350 GBF35_46545
FRE: Franean1_3137
AOI: AORI_4293
AJA: AJAP_17425
AMYC: CU254_29605
AMYB: BKN51_14545
AAB: A4R43_13530
AMYY: YIM_30690(hpcE)
AORI: SD37_21935
APRT: MUY14_14655
AROO: NQK81_44650
SESP: BN6_34230
KAL: KALB_2081 KALB_6021
KPHY: AOZ06_21965 AOZ06_35755
ALO: CRK57838
PMAD: BAY61_05700
ACTU: Actkin_03779(hpcE)
PFLA: Pflav_030060
PSUU: Psuf_055530
TBW: NCTC13354_01145(hpcE)
TPEC: HLG82_09300
FSL: EJO69_09695
FLH: EJ997_11170
WIK: H8R18_06690
SBAE: DSM104329_05499
KBS: EPA93_14145 EPA93_14160
THUG: KNN16_07270
STI: Sthe_2803
DRA: DR_A0226
DGE: Dgeo_2413
DDR: Deide_2p00090
DMR: Deima_1881
DPT: Deipr_2617
DGO: DGo_CA0560
DPD: Deipe_0880
DWU: DVJ83_13490
DFC: DFI_17480
DEIN: DAAJ005_01850
DGA: DEGR_32280
DPH: EHF33_17495
DRD: LMT64_12500
DAH: DAETH_34990
TRA: Trad_1892
TTH: TT_C0592
TTJ: TTHA0958(TTHA0958)
TTS: Ththe16_0954
TTL: TtJL18_1094
TSC: TSC_c10430(hpaG)
THC: TCCBUS3UF1_12450
TOS: Theos_0970
TAQ: TO73_1004
TPAR: AV541_05920
TBC: A0O31_00121
TANT: KNN15_10275
MRB: Mrub_1334
MRE: K649_06325
MTAI: Mtai_v1c16410
MSV: Mesil_2309
MHD: Marky_1262
UAM: UABAM_05976
LAJ: A0128_07340
HALY: HYG82_08525
 » show all
Reference
1  [PMID:7026235]
  Authors
Garrido-Peritierra A, Cooper RA
  Title
Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli.
  Journal
Eur J Biochem 117:581-4 (1981)
DOI:10.1111/j.1432-1033.1981.tb06377.x
Reference
2
  Authors
Johnson, W.H., Jr., Hajipour, G. and Whitman, C.P.
  Title
Characterization of a dienol intermediate in the 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase reaction.
  Journal
J Am Chem Soc 114:11001-11003 (1992)
Reference
3
  Authors
Johnson, W.H., Jr., Hajipour, G. and Whitman, C.P.
  Title
Stereochemical studies of 5-(carboxymethyl)-2-hydroxymuconate isomerase and 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase from Escherichia coli C: mechanistic and evolutionary implications.
  Journal
J Am Chem Soc 117:8719-8726 (1995)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.68
IUBMB Enzyme Nomenclature: 4.1.1.68
ExPASy - ENZYME nomenclature database: 4.1.1.68
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.68
BRENDA, the Enzyme Database: 4.1.1.68

  All links  
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (2286)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1358)   
   KEGG MGENES (839)   
   RefGene (88)   
Protein sequence (632)   
   UniProt (618)   
   SWISS-PROT (3)   
   RefSeq(pep) (7)   
   PDBSTR (4)   
DNA sequence (1022)   
   RefSeq(nuc) (13)   
   GenBank (506)   
   EMBL (503)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   InterPro (4)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (3961)   

Download RDF
DBGET integrated database retrieval system