KEGG   ENZYME: 4.1.1.68
Entry
EC 4.1.1.68                 Enzyme                                 
Name
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase;
5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase;
5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase;
5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
(3E,5R)-5-carboxy-2-oxohept-3-enedioate carboxy-lyase [(4Z)-2-oxohept-4-enedioate-forming]
Reaction(IUBMB)
(3E,5R)-5-carboxy-2-oxohept-3-enedioate = (4Z)-2-oxohept-4-enedioate + CO2 (overall reaction) [RN:R04133];
(1a) (3E,5R)-5-carboxy-2-oxohept-3-enedioate = (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate + CO2;
(1b) (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate = (4Z)-2-oxohept-4-enedioate
Reaction(KEGG)
R04133;
(other) R04380
Substrate
(3E,5R)-5-carboxy-2-oxohept-3-enedioate;
(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate
Product
(4Z)-2-oxohept-4-enedioate;
CO2 [CPD:C00011];
(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate
Comment
Requires Mg2+ [2,3]. Part of the 4-hydroxyphenylacetate degradation pathway in Escherichia coli.
History
EC 4.1.1.68 created 1984
Pathway
ec00350  Tyrosine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05921  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
Genes
EOI: ECO111_5214(hpcE)
EOJ: ECO26_5557(hpcE)
EOH: ECO103_5136(hpcE)
ECOO: ECRM13514_5608
ECOH: ECRM13516_5322
ECOA: APECO78_02920
ECX: EcHS_A4584(hpaG)
ECY: ECSE_4629
ECR: ECIAI1_4575(hpaG)
EUM: ECUMN_4975(hpaG)
EBR: ECB_04230(hpaG)
EBL: ECD_04230(hpaG)
EBE: B21_04196(ybl228)
EBD: ECBD_3666
ECL: EcolC_3702
EKF: KO11_23405(hpaG)
ELW: ECW_m4713(hpaG)
ELL: WFL_22960(hpaG)
ECOL: LY180_22840
EFE: EFER_3062(hpaG)
ESF: ACK8NJ_20155(hpaG)
STY: STY1134(hpaG)
STT: t1818(hpaG)
SEX: STBHUCCB_19340
SENT: TY21A_09255
STM: STM1101(hpaG)
SEO: STM14_1250(hpaG)
SEV: STMMW_11111
SEY: SL1344_1040(hpaG)
SEM: STMDT12_C11200
SEJ: STMUK_1070(hpaG)
SEB: STM474_1093(hpaG)
SEF: UMN798_1143(hpaG)
SETU: STU288_01835
SETC: CFSAN001921_11670
SENR: STMDT2_10371(hpaG)
SEND: DT104_10831(hpaG)
SENI: CY43_05625
SEEN: SE451236_11355
SPQ: SPAB_02452
SEI: SPC_2649(hpaG)
SEC: SCH_1051(hpaG)
SEH: SeHA_C1211
SHB: SU5_01732
SENH: CFSAN002069_03515
SEEH: SEEH1578_14730
SEE: SNSL254_A1196
SENN: SN31241_21680
SEW: SeSA_A1165
SEA: SeAg_B1060
SENS: Q786_04920
SED: SeD_A1176
SEG: SG0990(hpaG)
SEL: SPUL_1956(hpaG)
SEGA: SPUCDC_1942(hpaG)
SET: SEN0965(hpaG)
SENA: AU38_04980
SENO: AU37_04970
SENV: AU39_04970
SENQ: AU40_05585
SENL: IY59_05070
SENJ: CFSAN001992_06140
SEEC: CFSAN002050_11900
SEEB: SEEB0189_014065
SEEP: I137_08890
SENB: BN855_10560(hpaG)
SENE: IA1_05420
SENC: SEET0819_12165
SES: SARI_01901
SBG: SBG_0947(hpaG)
SBZ: A464_1041
SALZ: EOS98_14110
SFL: SF4384(hpaG)
SFX: S4654(hpaG)
SFV: SFV_4384(hpaG)
SFE: SFxv_4778
SFN: SFy_6292
SFS: SFyv_6362
SFT: NCTC1_04760(hpaG)
SSN: SSON_4499(hpaG)
SBO: SBO_4412(hpaG)
SBC: SbBS512_E4890(hpaG)
SHQ: A0259_03545
SHIG: LXH19_19105
ENC: ECL_00758
ENL: A3UG_03040
ECLG: EC036_05950
ECLE: ECNIH2_03940
ECLN: ECNIH4_19860
ECLI: ECNIH5_03065
ECLX: LI66_03060
ECLY: LI62_03530
ECLZ: LI64_03035
ECLO: ENC_44720
EHM: AB284_21945
EXF: BFV63_03015
ECLA: ECNIH3_03065
ECLC: ECR091_03045
EAU: DI57_15580
EKB: BFV64_02680
ENO: ECENHK_03135
EEC: EcWSU1_00557(hpaG)
ELG: BH714_17665
ECAN: CWI88_19255
ERN: BFV67_02850
ECLS: LI67_003995
ECHG: FY206_03570
ESH: C1N69_02900
EPT: HWQ17_09590
ECHU: RQP59_03460(hpaG)
EAS: Entas_0536
ENX: NI40_002905
LNI: CWR52_09205
EBG: FAI37_03645
ENZ: G0034_02930
ENS: HWQ15_11470
ENK: LOC22_13810
EHU: D5067_0019995
EMOR: L6Y89_02840
ENB: ELK40_03630
EQU: OM418_02880(hpaG)
EPU: QVH39_02925(hpaG)
EDY: F0320_02685(hpaG)
EAX: AAHF05_02855(hpaG)
ENTE: GXP72_03040
ENTY: H2Z33_04955
KPN: KPN_04788(hpaG) KPN_04789(hpaG)
KPU: KP1_0742(hpaG2) KP1_0743(hpaG1)
KPM: KPHS_06340 KPHS_06350
KPP: A79E_4363 A79E_4364
KPH: KPNIH24_03265 KPNIH24_03270
KPZ: KPNIH27_03140 KPNIH27_03145
KPV: KPNIH29_03455 KPNIH29_03460
KPW: KPNIH30_03415 KPNIH30_03420
KPY: KPNIH31_04645 KPNIH31_04650
KPG: KPNIH32_03420 KPNIH32_03425
KPC: KPNIH10_03245 KPNIH10_03250
KPQ: KPR0928_03255 KPR0928_03260
KPT: VK055_2650(hpaG) VK055_2651
KPO: KPN2242_02075 KPN2242_02080
KPR: KPR_0867(hpaG2) KPR_0868(hpaG)
KPJ: N559_4507 N559_4508
KPI: D364_24395 D364_24400
KPA: KPNJ1_04823 KPNJ1_04824
KPS: KPNJ2_04771 KPNJ2_04772
KPX: PMK1_02247(hpcE_1) PMK1_02248(hpcE_2)
KPB: FH42_20460 FH42_20465
KPNE: KU54_023325 KU54_023330
KPNU: LI86_23165 LI86_23170
KPNK: BN49_4405(hpaG) BN49_4406(hpaG2)
KVA: Kvar_4463 Kvar_4464
KPE: KPK_4831 KPK_4832
KPK: A593_13995 A593_14000
KVD: KR75_11445 KR75_11450
KVQ: SP68_18080 SP68_18085
KQU: AVR78_07790 AVR78_07795
KQV: B8P98_24195 B8P98_24200
KOX: KOX_10055 KOX_10060
KOE: A225_0713 A225_0714
KOY: J415_27675 J415_27680
KOM: HR38_08780 HR38_08785
KOK: KONIH1_03780 KONIH1_03785
KOC: AB185_32405 AB185_32410
EAE: EAE_10355 EAE_10360
EAR: CCG31923 CCG31924
KLL: BJF97_04330 BJF97_04335
KLW: DA718_24745 DA718_24750
KAR: LGL98_21800 LGL98_21805
KGR: JJJ10_24210 JJJ10_24215
KPAS: LUW96_10320 LUW96_10325
KLC: K7H21_24350 K7H21_24355
KLM: BWI76_03870 BWI76_03875
REE: electrica_04371(hpcE_1) electrica_04372(hpcE_2)
KLP: GUC22_23445 GUC22_23450
KLX: GQR96_03070 GQR96_03075
ROR: RORB6_15520 RORB6_15525
RON: TE10_05495 TE10_05500
RPLN: B1209_23480 B1209_23485
RAO: DSD31_22235 DSD31_22240
RTG: NCTC13098_06415(hpcE_1) NCTC13098_06416(hpcE_2)
CBRA: A6J81_18545 A6J81_18550
EBT: EBL_c33950(hpcE) EBL_c33960(hpaG)
PGE: LG71_25455
ESC: Entcl_3797
KLE: AO703_02930
KIE: NCTC12125_02702(hpcE_1) NCTC12125_02703(hpcE_2)
KAS: KATP_35240
KLU: K7B04_10625
KCY: RIN60_17960(hpaG)
LAX: APT61_19305
LEI: C2U54_08015
LEH: C3F35_08675
LEE: DVA44_20810
LER: GNG29_03260
LEA: GNG26_02815
LPNU: KQ929_17865
LEY: DVA43_14690
BUF: D8682_01725 D8682_01730
BFT: MNO13_13765 MNO13_13770
YRE: HEC60_20825
IZH: FEM41_12635
PSGC: G163CM_29740(hpcE)
TOE: QMG90_18580(hpaG)
EBF: D782_3919
EBU: CUC76_12045
EBB: F652_2359 F652_2360
YPH: YPC_2520 YPC_2521
YPA: YPA_1133 YPA_1134
YPN: YPN_2361 YPN_2362
YPP: YPDSF_1361 YPDSF_1362
YPZ: YPZ3_1956 YPZ3_1957
YPT: A1122_17055 A1122_17060
YPD: YPD4_1559 YPD4_1560
YPX: YPD8_1994 YPD8_1995
YPW: CH59_3405(hpaG) CH59_3406(hpaG)
YPJ: CH55_916(hpaG) CH55_917(hpaG)
YPV: BZ15_1787(hpaG) BZ15_1788(hpaG)
YPL: CH46_3361(hpaG) CH46_3362(hpaG)
YPS: YPTB1637(hpaG) YPTB1638
YPO: BZ17_864(hpaG) BZ17_865(hpaG)
YPI: YpsIP31758_2364(hpaG2) YpsIP31758_2365(hpaG1)
YPY: YPK_2460 YPK_2461
YPB: YPTS_1761 YPTS_1762
YPQ: DJ40_585(hpaG) DJ40_586(hpaG)
YPU: BZ21_987(hpaG) BZ21_988(hpaG)
YPR: BZ20_337(hpaG) BZ20_338(hpaG)
YPC: BZ23_1265(hpaG) BZ23_1266(hpaG)
YPF: BZ19_1064(hpaG) BZ19_1065(hpaG)
SMAR: SM39_4958(hpcE1) SM39_4959(hpcE2)
SMAC: SMDB11_4701(hpcE1) SMDB11_4702(hpcE2)
SMW: SMWW4_v1c05810 SMWW4_v1c05820
SPE: Spro_0625 Spro_0626
SRR: SerAS9_0561 SerAS9_0562
SRL: SOD_c04930(hpaG1) SOD_c04940(hpaG)
SRY: M621_02605 M621_02610
SPLY: Q5A_002595(hpcE_1) Q5A_002600(hpcE_2)
SRS: SerAS12_0561 SerAS12_0562
SRA: SerAS13_0561 SerAS13_0562
SMAF: D781_0569 D781_0570
SLQ: M495_02470 M495_02475
SERF: L085_01190 L085_01195
SERS: SERRSCBI_02745 SERRSCBI_02750
SFW: WN53_11465 WN53_11470
SFG: AV650_06750 AV650_06755
SRZ: AXX16_4538 AXX16_4539
SERM: CLM71_02755 CLM71_02760
SQU: E4343_13525 E4343_13530
SFJ: SAMEA4384070_0652(hpcE_1) SAMEA4384070_0653(hpcE_2)
SOF: NCTC11214_00932(hpcE_1) NCTC11214_00933(hpcE_2)
SSUR: ATE40_023585 ATE40_023590
SURI: J0X03_21075 J0X03_21080
SRHZ: FO014_07080 FO014_07085
SENP: KHA73_02640 KHA73_02645
SNEM: NLX84_02785 NLX84_02790
SNEV: OI978_03650 OI978_03655
SGRI: SGBXF1_00562(hpcE_1) SGBXF1_00563(hpcE_2)
SSAR: SSARUM_000547 SSARUM_000548
SERB: QEP77_20095 QEP77_20100
SERN: GUC32_02755 GUC32_02760
SERT: TAN611_0639 TAN611_0640
SERH: GF111_09965 GF111_09970
SFO: Z042_16795 Z042_16800
NIG: C1N62_19335
PROD: PCO85_15720
EPE: CI789_23885
ERWE: GKQ23_00460
PLU: plu0989(hpaG2) plu0990(hpaG1)
PLUM: A4R40_04945 A4R40_04950
PAY: PAU_00932(hpaG2) PAU_00933(hpaG1)
PTT: VY86_12505 VY86_12510
PAKH: B0X70_05375 B0X70_05380
PLUI: CE143_05305 CE143_05310
XBO: XBJ1_0866 XBJ1_0867
XBV: XBW1_1478(hpaG) XBW1_1479
XNE: XNC1_0822 XNC1_0823
XNM: XNC2_0807 XNC2_0808
XDO: XDD1_1025(hpaG2) XDD1_1026(hpaG1)
XHO: A9255_20610 A9255_20615
XBU: HGO23_05375 HGO23_05380
XGR: QL128_15680 QL128_15685
PSI: S70_06425 S70_06430
PSX: DR96_1982(hpaG) DR96_1983(hpaG)
PSTA: BGK56_09465 BGK56_09470
PTHA: OI982_17165 OI982_17170
PRG: RB151_008130(hpcE_1) RB151_008140(hpcE_2)
PALA: CO695_00740 CO695_00745
PHEI: NCTC12003_00826(hpcE_1) NCTC12003_00827(hpcE_2)
PRQ: CYG50_11465 CYG50_11470
PRJ: NCTC6933_00884(hpcE_1) NCTC6933_00885(hpcE_2)
PVC: G3341_03910 G3341_03915
PMAG: JI723_04370 JI723_04375
PHAG: PZ638_04005 PZ638_04010
PZJ: QS795_003570 QS795_003575
PZN: ACE2AM_04055 ACE2AM_04060
PXH: ACE2AL_03950 ACE2AL_03955
MWI: MNY66_12690
ETE: ETEE_3251(hpaG) ETEE_3252(hpaG)
EDW: QY76_13795 QY76_13800
EDL: AAZ33_06655 AAZ33_06660
HAV: AT03_16910 AT03_16915
HPAR: AL518_09740 AL518_09745
OPO: DSM2777_08310 DSM2777_08315
PRAG: EKN56_03330 EKN56_03335
PFQ: QQ39_14455 QQ39_14460
PMU: PM1528(hpaG_1) PM1529(hpaG_2)
PMV: PMCN06_1795(hpaG1) PMCN06_1796(hpaG2)
PUL: NT08PM_1855 NT08PM_1856
PMP: Pmu_17950(hpaG1) Pmu_17960(hpaG2)
PMUL: DR93_377(hpaG) DR93_378(hpaG)
PCAI: K7G93_001652 K7G93_001653
GSS: NYR30_10215 NYR30_10220
FAU: Fraau_1724 Fraau_1725
VVY: VV1583 VV1584
VNI: VIBNI_B1954 VIBNI_B1955
VSI: MTO69_16170 MTO69_16175
VMI: AL543_16430 AL543_16435
PRE: PCA10_16340(hpaG2) PCA10_16350(hpaG1)
PFUW: KF707C_32020 KF707C_32030
POJ: PtoMrB4_16790 PtoMrB4_16800
PAE: PA4121 PA4122
PAEV: N297_4253(hpaG) N297_4254(hpaG)
PAEI: N296_4253(hpaG) N296_4254(hpaG)
PAU: PA14_10640(hpaG2) PA14_10650(hpaG1)
PAG: PLES_08491 PLES_08501
PAF: PAM18_0817 PAM18_0818
PNC: NCGM2_5322(hpaG1) NCGM2_5323(hpaG2)
PAEB: NCGM1900_0838(hpaG2) NCGM1900_0839(hpaG1)
PSG: G655_04090 G655_04095
PRP: M062_21735 M062_21740
PAEP: PA1S_04210 PA1S_04215
PAER: PA1R_gp2012 PA1R_gp2013
PAEM: U769_04235 U769_04240
PAEL: T223_04145 T223_04150
PAES: SCV20265_0845 SCV20265_0846
PAEU: BN889_04575 BN889_04576
PAEG: AI22_29400 AI22_29405
PAEC: M802_4251(hpaG) M802_4252(hpaG)
PAEO: M801_4119(hpaG) M801_4120(hpaG)
SECH: B18_03720 B18_03725
PCQ: PcP3B5_43380(hpcE_1) PcP3B5_43390(hpcE_2)
PAP: PSPA7_0970 PSPA7_0971
PPAA: B7D75_04080 B7D75_04085
PPG: PputGB1_3496 PputGB1_3497
PPUN: PP4_18990(hpaG2) PP4_19000(hpaG1)
PMOL: CLJ08_25220 CLJ08_25225
PMOS: O165_009150 O165_009155
PFUV: NLK61_02530 NLK61_02535
PFL: PFL_3370(hpaG_1) PFL_3371(hpaG_2)
PPRC: PFLCHA0_c34000(hpaG1) PFLCHA0_c34010(hpaG2)
PPRO: PPC_3394(hpaG_1) PPC_3395
PFE: PSF113_2550 PSF113_2551
PZA: HU749_016605 HU749_016610
PFN: HZ99_06960 HZ99_06965
PFS: PFLU_3269 PFLU_3270
PFC: PflA506_3394(hpaG_1) PflA506_3395(hpaG_2)
PFB: VO64_1095 VO64_1096
PTV: AA957_24925 AA957_24930
PCG: AXG94_00030 AXG94_00035
PAZO: AYR47_26775 AYR47_26780
PMED: E3Z27_12230 E3Z27_12235
PMAB: U0037_16330 U0037_16335
PBRE: QDY63_11685 QDY63_11690
PFW: PF1751_v1c34780(hpaG) PF1751_v1c34790(hpaG)
PFF: PFLUOLIPICF718510 PFLUOLIPICF718515
PEN: PSEEN3092(hpaG-1) PSEEN3093(hpaG-2)
PLUL: FOB45_04655 FOB45_04660
PBA: PSEBR_a2743 PSEBR_a2744
PBC: CD58_13845 CD58_13850
PDR: H681_09015 H681_09020
PSK: U771_17275 U771_17280
PKC: PKB_2458(hpaG) PKB_2459
PCH: EY04_16730 EY04_16735
PCZ: PCL1606_27020 PCL1606_27030
PCP: JM49_14000 JM49_14005
PCHP: C4K32_3446 C4K32_3447
PSW: LK03_18015 LK03_18020
PSES: PSCI_3411 PSCI_3412
PSEM: TO66_17385 TO66_17390
PSEC: CCOS191_2707(hpaG1) CCOS191_2708(hpaG2)
PSOS: POS17_3351(hpaG_1) POS17_3352
PANR: A7J50_3678 A7J50_3679
PSET: THL1_2752 THL1_2753
PYM: AK972_3748 AK972_3749
PVK: EPZ47_13775 EPZ47_13780
PEZ: HWQ56_10205 HWQ56_10210
PBZ: GN234_04530 GN234_04535
PDW: BV82_3347 BV82_3348
PSEP: C4K39_5339 C4K39_5340
PPII: QL104_17915 QL104_17920
PVW: HU752_019655 HU752_019660
PTRT: HU722_0018750 HU722_0018755
PSAM: HU731_005385 HU731_005390
PQI: KH389_12140 KH389_12145
PSHH: HU773_017835 HU773_017840
PXN: HU772_013365 HU772_013370
PPRG: HU725_013735 HU725_013740
PASG: KSS96_11970 KSS96_11975
PMUY: KSS95_15015 KSS95_15020
PMAM: KSS90_12435 KSS90_12440
PCAS: LOY40_17105 LOY40_17110
PORY: EJA05_13170 EJA05_13175
PTK: EXN22_12280 EXN22_12285
PTW: TUM18999_28840 TUM18999_28850
PSIH: LOY51_12990 LOY51_12995
PKM: PZ739_17730 PZ739_17735
PSOA: PSm6_54000 PSm6_54010
PKK: QQ992_12765 QQ992_12770 QQ992_17450 QQ992_17455 QQ992_17605 QQ992_17610
PHYG: JTY93_17150 JTY93_17155
PCUC: PSH97_16030 PSH97_16035
PPAE: LDL65_00715 LDL65_00720
PRHZ: CRX69_05740 CRX69_05745
PHEF: PSH57_18325 PSH57_18330
PSNC: C0058_11550 C0058_11555
PBEJ: PSH84_18070 PSH84_18075
PKV: QYQ93_18745 QYQ93_18750
PDEU: QEP73_15680 QEP73_15685
PBEN: V6W80_13425 V6W80_13430
PCAA: V6L78_14540 V6L78_14545
PSIV: LZ023_16085 LZ023_16090 LZ023_25765 LZ023_25770
PTHV: CE140_06065 CE140_06070
PSSX: DCC84_12440 DCC84_12445
PSNS: CI807_26370 CI807_26375
PKH: JLK41_06115 JLK41_06120
EMO: DM558_04935 DM558_04940
EAZ: JHT90_12405 JHT90_12410
ENTO: MTZ49_06630 MTZ49_06635
MSQ: BKP64_00775 BKP64_00780
ABAZ: P795_8015 P795_8020
ABK: LX00_09745 LX00_09750
ABAU: IX87_20485 IX87_20490
ABOU: ACBO_11640 ACBO_11650
ACIU: A3K93_02895 A3K93_02900
ALCA: ASALC70_00927(hpcE_1) ASALC70_00928(hpcE_2) ASALC70_03596(hpcE_3) ASALC70_03597(hpcE_4)
ADI: B5T_01361 B5T_01362 B5T_03291 B5T_03292
AXE: P40_15415 P40_15420
MMW: Mmwyl1_3176 Mmwyl1_3177
MPRI: MP3633_3049 MP3633_3050
MRHI: KDW99_14225 KDW99_14230
MGEO: CFI10_04480 CFI10_04485
MSEC: LN244_12200 LN244_12205
MARL: HH196_02935
NJP: NEJAP_1966 NEJAP_1967
AJP: AMJAP_1984 AMJAP_1985
EMP: EZMO1_0441(hpaG1) EZMO1_0445(hpaG2)
IGN: MMG00_10975 MMG00_10980
VFF: VITFI_CDS3299 VITFI_CDS3300
CRZ: D1345_13720 D1345_13725
CHAE: CH06BL_29030 CH06BL_29040
AMAH: DLM_0617 DLM_0618
AQS: DKK66_02100 DKK66_02105
AQL: BXU06_01530 BXU06_01535
RPI: Rpic_1959 Rpic_1960
RPF: Rpic12D_1631 Rpic12D_1632
RMN: TK49_12430 TK49_12435
RIN: ACS15_1519 ACS15_1520
RWE: KOL96_16030 KOL96_16035
CBW: RR42_s1465 RR42_s1466
CCUP: BKK81_27570 BKK81_27575
CUP: BKK80_28750 BKK80_28755
CUU: BKK79_34700 BKK79_34705
BMA: BMAA1139 BMAA1140
BML: BMA10229_0100 BMA10229_0101
BMN: BMA10247_A1512 BMA10247_A1513
BMAZ: BM44_4561(hpaG) BM44_4562(hpaG)
BMAL: DM55_4408(hpaG) DM55_4409(hpaG)
BMAE: DM78_3450(hpaG) DM78_3451(hpaG)
BMAQ: DM76_3358(hpaG) DM76_3359(hpaG)
BMAI: DM57_09675 DM57_09680
BMAF: DM51_4808(hpaG) DM51_4809(hpaG)
BMAB: BM45_3686(hpaG) BM45_3687(hpaG)
BPS: BPSS0692 BPSS0693
BPM: BURPS1710b_A2263(hpaG) BURPS1710b_A2264(hpaG)
BPL: BURPS1106A_A0938 BURPS1106A_A0939
BPD: BURPS668_A1023 BURPS668_A1024
BPR: GBP346_B0216(hpaG_1) GBP346_B0217(hpaG_2)
BPSE: BDL_3923(hpaG) BDL_3924(hpaG)
BPZ: BP1026B_II0765 BP1026B_II0766
BPK: BBK_3797(hpaG) BBK_3798(hpaG)
BPSH: DR55_4657(hpaG) DR55_4658(hpaG)
BPSA: BBU_5349(hpaG) BBU_5350(hpaG)
BPSO: X996_3875(hpaG) X996_3876(hpaG)
BUT: X994_3923(hpaG) X994_3924(hpaG)
BTE: BTH_II1734(hpaG-1) BTH_II1735(hpaG-2)
BTV: BTHA_5720(hpaG) BTHA_5721(hpaG)
BTHE: BTN_4147(hpaG) BTN_4148(hpaG)
BTHM: BTRA_3945(hpaG) BTRA_3946(hpaG)
BTHA: DR62_4182 DR62_4183
BTHL: BG87_4478(hpaG) BG87_4479(hpaG)
BOK: DM82_4771(hpaG) DM82_4772(hpaG)
BOC: BG90_5821(hpaG) BG90_5822(hpaG)
BUU: WS70_20785 WS70_20790
BSAV: WS86_22075 WS86_22080
BHG: I6G56_24635 I6G56_24640
BUD: AQ610_27300 AQ610_27305
BVI: Bcep1808_4801 Bcep1808_4802
BVE: AK36_4116(hpaG) AK36_4117
BUR: Bcep18194_B1782 Bcep18194_B1783
BCM: Bcenmc03_3285 Bcenmc03_3286
BCH: Bcen2424_4231 Bcen2424_4232
BCJ: BCAM1366(hpaG) BCAM1367(hpaG')
BCEN: DM39_3638(hpaG) DM39_3639(hpaG)
BCEW: DM40_4255(hpaG) DM40_4256(hpaG)
BCEO: I35_5218(hpaG) I35_5219(hpaG')
BAM: Bamb_3653 Bamb_3654
BAC: BamMC406_4127 BamMC406_4128
BMJ: BMULJ_04132(hpaG) BMULJ_04133
BMU: Bmul_4373 Bmul_4374
BMK: DM80_3536(hpaG) DM80_3537(hpaG)
BMUL: NP80_4258(hpaG) NP80_4259(hpaG)
BCT: GEM_4388 GEM_4389
BCED: DM42_3720(hpaG) DM42_3721(hpaG)
BCEP: APZ15_17830 APZ15_17835
BDL: AK34_4141(hpaG) AK34_4142(hpaG)
BPYR: ABD05_29365 ABD05_29370
BCON: NL30_05825 NL30_05830
BUB: BW23_5043(hpaG) BW23_5044(hpaG)
BDF: WI26_19825 WI26_19830
BLAT: WK25_23640 WK25_23645
BTEI: WS51_04520 WS51_04525
BSEM: WJ12_26630 WJ12_26635
BPSL: WS57_07260 WS57_07265
BMEC: WJ16_25220 WJ16_25225
BSTG: WT74_25590 WT74_25595
BSTL: BBJ41_19870 BBJ41_19875
BARI: NLX30_31765 NLX30_31770
BAEN: L3V59_19955 L3V59_19960
BSER: R0290_26050 R0290_26055
BUG: BC1001_5335 BC1001_5336
BGF: BC1003_4085 BC1003_4086
BUK: MYA_4420
BUL: BW21_5182(hpaG) BW21_5183(hpaG)
BUQ: AC233_23390 AC233_23395
BURK: DM992_19110 DM992_19115
BURM: GJG85_17875 GJG85_17880
BXE: Bxe_B2028 Bxe_B2029
BXB: DR64_7330 DR64_7331(hpaG)
BGE: BC1002_3575 BC1002_3576
BPX: BUPH_05747 BUPH_05748
BPY: Bphyt_5824 Bphyt_5825
BUZ: AYM40_23790 AYM40_23795
BFN: OI25_4430 OI25_4431(hpaG)
BCAI: K788_0007889 K788_0007890
PARB: CJU94_20035 CJU94_20040
PHS: C2L64_36765 C2L64_36770
PTER: C2L65_32255 C2L65_32260
PGP: CUJ91_20150 CUJ91_20155
PCJ: CUJ87_18055 CUJ87_18060
PTS: CUJ90_27700 CUJ90_27705
PCAF: DSC91_001880 DSC91_001881
PMEG: FNZ07_23060 FNZ07_23065
PTRO: G5S35_21205 G5S35_21210
PGIS: I6I06_20120 I6I06_20125
PACP: FAZ97_23285 FAZ97_23290
PACS: FAZ98_18680 FAZ98_18685
PDIO: PDMSB3_1098.1 PDMSB3_1099.1
PBRY: NDK50_31165 NDK50_31170
PSAA: QEN71_12025 QEN71_12030 QEN71_34370 QEN71_34375
PKF: RW095_10780 RW095_10785
PPAI: E1956_24550 E1956_24555
PLAD: PPGU16_72790 PPGU16_72800
PAZZ: PBP221_75240 PBP221_75250
BRH: RBRH_00354 RBRH_00355
PTX: ABW99_06770 ABW99_06775
HYF: DTO96_101731(hpcE_1) DTO96_101732(hpcE_2)
TVL: FAZ95_35535 FAZ95_35540
BPAR: BN117_0692(hpaG) BN117_0693
BBH: BN112_2700 BN112_2701(hpaG)
BBR: BB0734(hpaG) BB0735
BBM: BN115_0708(hpaG) BN115_0709
BBX: BBS798_0712(hpaG) BBS798_0713
BAV: BAV1264(hpaG') BAV1265(hpaG)
BGM: CAL15_06610 CAL15_06615
BOJ: CBF45_15795 CBF45_15800
AXY: AXYL_04173 AXYL_04174
AXO: NH44784_056751 NH44784_056761
AXN: AX27061_3933 AX27061_3934
AXX: ERS451415_03956(hpcE_1) ERS451415_03957(hpcE_2)
ADT: APT56_18385 APT56_18390
AIS: BUW96_10100 BUW96_10105
ASW: CVS48_22595 CVS48_22600
ACHR: C2U31_24570 C2U31_24575
ACHB: DVB37_16875 DVB37_16880
ADY: HLG70_03115 HLG70_03120
APES: FOC84_25020 FOC84_25025
AAEG: RA224_12255 RA224_12260
ASEL: RAS12_02580 RAS12_02585
ACHA: KYT87_17405 KYT87_17410
AVH: WHX56_23790 WHX56_23795
ACHH: ABFG95_03725 ABFG95_03730
AMIM: MIM_c17570(hpaG1) MIM_c17580(hpaG2)
CDN: BN940_16381 BN940_16386
KGY: EHF36_15845 EHF36_15850
PARK: LSG25_15100 LSG25_15105
RHF: EUB48_20500 EUB48_20505
RHOB: HTY51_15885 HTY51_15890
DAC: Daci_0107 Daci_0108
DEL: DelCs14_0109 DelCs14_0110
DTS: BI380_22280 BI380_22285
DHK: BO996_02450 BO996_02455
DLA: I6G47_22230 I6G47_22235
VAP: Vapar_0244 Vapar_0245
VPE: Varpa_0249 Varpa_0250
VPD: VAPA_1c02980 VAPA_1c02990 VAPA_1c22640 VAPA_1c22650
VBO: CKY39_01485 CKY39_01490
VAM: C4F17_17590 C4F17_17595
VAZ: H7F35_13315 H7F35_13320
VAV: IG196_00305 IG196_00310
VAE: RZE79_01510 RZE79_01515
COF: FOZ74_10680 FOZ74_10685
CODO: LAD35_15650 LAD35_15655
CRJ: QMY55_00305 QMY55_00310
RTA: Rta_01810 Rta_01820
RTEA: HK414_00995
OTK: C6570_01930 C6570_01935
LIM: L103DPR2_00424(hpcE_1) L103DPR2_00425(hpcE_2)
LIH: L63ED372_02764(hpcE_1) L63ED372_02765(hpcE_2)
HYR: BSY239_4290 BSY239_4291(hpaG)
HYB: Q5W_21325 Q5W_21330
HYL: LPB072_01775 LPB072_01780
HYC: E5678_16130 E5678_16135
HPSE: HPF_01680(hpcE1) HPF_01685(hpcE2)
HYN: F9K07_02245 F9K07_02250
HTN: KI616_01835 KI616_01840
HCZ: G9Q37_18480
HYY: JNX00_01560
HYDR: SOM08_01455 SOM08_01460
HYDA: ABSY19_12730 ABSY19_12735
DIH: G7047_25010 G7047_25015
DRG: H9K76_08025 H9K76_08030
KIA: G8A07_25155 G8A07_25160
SMIO: CATMQ487_02950 CATMQ487_02960(hpaG)
DECH: GBK02_02820 GBK02_02825
DAJ: VX159_15215 VX159_15220
QAU: KI612_13760 KI612_13765
AZR: CJ010_16660 CJ010_16665
ACOM: CEW83_16465 CEW83_16470
ALEG: CFBP4996_22110
SWI: Swit_4308 Swit_4309
SPCL: F9288_08630 F9288_08635
SPCA: GL174_14845 GL174_14850
AZS: E6C72_14800 E6C72_14805
MAG: amb0806 amb0807
STI: Sthe_2803
UAM: UABAM_05976
UHL: UABHE_003950
LAJ: A0128_07340
BCY: Bcer98_0971 Bcer98_0972
BFD: NCTC4823_03855(hpcE_1) NCTC4823_03856(hpcE_2)
BACO: OXB_3441 OXB_3442
BEO: BEH_12505 BEH_12510
PKS: IE339_14165 IE339_14170
BKO: CKF48_12840 CKF48_12845
OIH: OB2865 OB2866
LYQ: MY533_14975 MY533_14980
HHD: HBHAL_2376(hpaG1) HBHAL_2377(hpaG2)
HMN: HM131_18410 HM131_18415
HLI: HLI_19730 HLI_19735
HNZ: P9989_02585 P9989_02590
HSAN: MUN89_08205 MUN89_08210
HSHI: MUO14_16425 MUO14_16430
VIG: BKP57_18450 BKP57_18455
VIL: CFK37_10935 CFK37_10940
VPN: A21D_03940(hpcE_1) A21D_03941(hpcE_2)
VPT: KBP50_11255 KBP50_11260
VSS: PD280_19935
APAK: AP3564_00600 AP3564_00605
ACOP: RI196_16870 RI196_16875
BSJ: UP17_15180 UP17_15185
BMUR: ABE28_014070 ABE28_014075
PFRI: L8956_15900 L8956_15905
PERJ: JNUCC41_24830 JNUCC41_24835
PSYH: D0S48_01890 D0S48_01895
PSYO: PB01_19040 PB01_19045
RUE: DT065_14075 DT065_14080
POF: GS400_10250 GS400_10255
PCHU: QNI29_07215 QNI29_07220
PONA: IMZ31_06060 IMZ31_06065
NMK: CHR53_10005 CHR53_10010
MSEM: GMB29_05705 GMB29_05710
MENL: MVE64_18445 MVE64_18450
MSEE: WCV65_07090 WCV65_07095
BVJ: I5776_15175 I5776_15180
BOU: I5818_18870 I5818_18875
HSPO: JGZ69_00750 JGZ69_00755
CTHU: HUR95_08540
FHL: OE105_04750 OE105_04755
FAF: OE104_06415 OE104_06420
SFOR: QNH23_14305 QNH23_14310
ALKG: MOJ78_08045
BBAD: K7T73_16275 K7T73_16280
FPN: ABE65_007010
FAR: ABE41_008065
FEC: QNH15_09395
GKA: GK3030 GK3031
GTE: GTCCBUS3UF5_33900 GTCCBUS3UF5_33910
GTK: GT3570_14780 GT3570_14785
GTM: GT3921_03970 GT3921_03975
GLI: GLN3_07905
BCAL: CWI35_12860 CWI35_12865
GTN: GTNG_2988 GTNG_2989
GYC: GYMC61_3109 GYMC61_3110
GYA: GYMC52_3136 GYMC52_3137
GCT: GC56T3_0473 GC56T3_0474
GMC: GY4MC1_0467 GY4MC1_0468
GGH: GHH_c31040(hpaG1) GHH_c31050(hpaG2)
GJF: M493_15785 M493_15790
GSE: GT50_06855 GT50_06860
GEJ: A0V43_13000 A0V43_13005
GZA: IC807_11275 IC807_11280
GTH: Geoth_0535 Geoth_0536
PTL: AOT13_00520 AOT13_00525
PTB: DER53_14655 DER53_14660
PARG: PspKH34_04500 PspKH34_04510
PCAL: BV455_02284(hpcE_1) BV455_02285(hpcE_2)
ANM: GFC28_1566(hpaG) GFC28_1567(hpaG)
ANL: GFC29_61(hpaG) GFC29_62(hpaG)
AND: GRQ40_05065 GRQ40_05070
AAMY: GFC30_1750
HYI: K2M58_06390 K2M58_06395
SBAH: RQP18_12075 RQP18_12080
PSOP: KP014_02190
PTHI: NDS46_23235 NDS46_23240
PDY: QJQ58_28950 QJQ58_28955
PAUB: PUR_50070
ANX: ACH33_14100
ASOC: CB4_02466(hpcE_2) CB4_02467(hpcE_3)
ATHE: K3F53_04810
AUD: PO771_09065 PO771_09070
AAC: Aaci_0337
AAD: TC41_0457(hpaG)
ACYC: JI721_10945 JI721_10950
ALIC: GI364_04710 GI364_04715
BTS: Btus_1575
KYR: CVV65_08560
EFF: skT53_05540
SPSY: AZE41_13980 AZE41_13985
STHO: QNH10_13655
SOW: QWT69_13585 QWT69_13590
SPOH: GGGNBK_09485 GGGNBK_09490(ycgM)
PANC: E2636_17190 E2636_17195
TMR: Tmar_1820
TCP: Q5761_09440
SAY: TPY_2464(hpaG)
SAP: Sulac_3218
STHR: BXT84_13335
MMC: Mmcs_2606
MKM: Mkms_2650
CAR: cauri_2501(hpaG)
CHN: A605_03330
CAZ: CARG_02965
CCG: CCASEI_13870
CEI: CEPID_11900(hpaG)
CTED: CTEST_00865
CSP: WM42_1477
CSTA: CSTAT_12885
CPHO: CPHO_12180
CFC: CFLV_12710
CSTR: CBE89_01305
CAMG: CAMM_12570
CMIN: NCTC10288_00048(odx)
CPEG: CPELA_07995(hpcE)
CGK: CGERO_03120(hpcE)
CPSO: CPPEL_08230(hpcE)
CPRP: I6I69_06100
COK: COCCU_13940(hpcE)
CHIN: J5O04_02290
CFAC: CFAEC_07000(hpcE)
CATR: CATRI_00875(hpcE)
CHES: R3O64_12660
NFA: NFA_27790
NFR: ERS450000_01316(hpcE)
NBR: O3I_022370
NVU: V7968_30080
RHS: A3Q41_02967(hpcE)
GPO: GPOL_c33220(hpaG)
STRT: A8713_00810
SBY: H7H31_00375
SBAT: G4Z16_05460
SAKB: K1J60_42510
KBU: Q4V64_50710
LEIF: HF024_06175
LSE: F1C12_06800 F1C12_09785
MTS: MTES_0674
MIM: AKG07_00130
MIP: AXH82_11160
MCW: A8L33_07020
MPAL: BO218_07715
MIH: BJP65_05165
MICR: BMW26_04690
MAUR: BOH66_13310
MHOS: CXR34_14345
MFOL: DXT68_04810
MOO: BWL13_01224(hpcE_1) BWL13_02301(hpcE_2)
MLV: CVS47_00665(hpcE)
MWA: E4K62_04365
MPRT: ET475_02110
MOY: CVS54_01108(hpcE_1)
MCAW: F6J84_11775
MLZ: F6J85_04145
MRN: K8F61_08655
MICS: C1N74_03240
MLIQ: NMQ05_05670
MPAO: IZR02_04490
MAZA: NFX31_04465
MNF: JSY13_02685
MSUW: GCM10025863_16490
MARK: QUC20_03095
MEST: PTQ19_03985
MPLN: VC184_02955
MAUG: KV397_11905
MSUF: KV394_10040
MGAB: KV396_11195
MVD: AWU67_11415
AGY: ATC03_14640
AGM: DCE93_10215
AGF: ET445_16275
CPHY: B5808_00950
HUM: DVJ78_01710
HUW: FPZ11_13360
PLAP: EAO79_07080
LEU: Leucomu_10285
LTR: EVS81_13565
LVI: G7068_04845
LINS: G7067_06750
LLUT: K1X41_14320
AGG: C1N71_04410
ARR: ARUE_c40620(hpaG)
ARM: ART_3194
ARL: AFL94_06495
ARE: AL755_14115
AAQ: AOC05_17490
ARW: MB46_07065
ARH: AHiyo8_37340
ARY: ATC04_11475
ARU: ASPU41_04210
ARQ: BWQ92_08645
ARN: CGK93_21760
ARX: ARZXY2_1954
ACRY: AC20117_21420
ARTH: C3B78_18115
ARTP: E5206_11290
AAGI: NCTC2676_1_02908(hpcE)
AJG: KKR91_08325
ASUN: KG104_08610
APOA: J0916_16265
AWW: G8758_09265
AKO: N9A08_15345
AJR: N2K98_15895
ARTT: IG195_18005
ARTL: ArtHe_13775
ARI: UM93_06770
AAU: AAur_3917 AAur_pTC20089
PUE: FV140_10290
PNV: JMY29_18945
PAYJ: HMI59_11720
PAGO: IRJ34_19445
PAYN: HMI60_18990
PHRZ: QN084_21565
ARZ: AUT26_10015
ACH: Achl_3608
APN: Asphe3_34980
PSUL: AU252_22400
PSNI: NIBR502771_07020
PSEY: GU243_03860
PDEL: JCQ34_17665
POK: SMD14_18630
PSLS: KTR40_17355
PQA: WHH00_00585
AAI: AARI_13310
GAR: AOZ07_06925
GCR: GcLGCM259_1109
GLU: F0M17_06650
GPR: JQN66_06865
RSA: RSal33209_1507
KRH: KRH_22050
KFV: AS188_00920
KII: KocCE7_11975
KOD: HBK84_11860
KVR: CIB50_0000836(hpcE)
MLU: Mlut_19980
MICK: B1A86_00009910
RAMA: IDM48_07780
RKR: I6G21_04660
SATK: SA2016_2476
CCYC: SCMU_24600
AUL: DCC27_010305
AIG: QDX25_10300
CIG: E7744_13795
BCV: Bcav_0869
BRZ: CFK38_04890
BSAU: DWV08_11475
XYL: ET495_05310
IVA: Isova_1677
CFI: Celf_2072
CELH: GXP71_06015
SERJ: SGUI_0718
ORZ: FNH13_15065
OCP: NF557_12940
BLY: A2T55_04345
BLIN: BLSMQ_0804
BLUT: EW640_09465
BCAU: I6G59_07115
BSPO: L1F31_04405
BREB: PGC08_04380
BREJ: LJ362_03300
BKR: AAFP32_03130
MIK: FOE78_02955
MICG: GJV80_01435
SRO: Sros_7522
NOW: GBF35_28350 GBF35_46545
AOI: AORI_4293
AJA: AJAP_17425
AMYC: CU254_29605
AMYB: BKN51_14545
AAB: A4R43_13530
AMYY: YIM_30690(hpcE)
AORI: SD37_21935
APRT: MUY14_14655
AROO: NQK81_44650
ACOR: LCL61_23105
SESP: BN6_34230
KAL: KALB_6021
KPHY: AOZ06_21965
ALO: CRK57838
PMAD: BAY61_05700
ACTU: Actkin_03779(hpcE)
PFLA: Pflav_030060
PSUU: Psuf_055530
TBW: NCTC13354_01145(hpcE)
TPEC: HLG82_09300
FSL: EJO69_09695
FLH: EJ997_11170
WIK: H8R18_06690
KBS: EPA93_14160
THUG: KNN16_07270
DRA: DR_A0226
DGE: Dgeo_2413
DDR: Deide_2p00090
DMR: Deima_1881
DPT: Deipr_2617
DGO: DGo_CA0560
DPD: Deipe_0880
DWU: DVJ83_13490
DFC: DFI_17480
DEIN: DAAJ005_01850
DGA: DEGR_32280
DPH: EHF33_17495
DRD: LMT64_12500
DAH: DAETH_34990
DTAE: LAJ19_18060
DMB: E5F05_03840
DEID: HLB42_19550
TRA: Trad_1892
TTH: TT_C0592
TTJ: TTHA0958(TTHA0958)
TTS: Ththe16_0954
TTL: TtJL18_1094
TSC: TSC_c10430(hpaG)
THC: TCCBUS3UF1_12450
TOS: Theos_0970
TAQ: TO73_1004
TPAR: AV541_05920
TBC: A0O31_00121
TANT: KNN15_10275
MRB: Mrub_1334
MRE: K649_06325
MTAI: Mtai_v1c16410
MSV: Mesil_2309
MHD: Marky_1262
HALY: HYG82_08525
 » show all
Reference
1  [PMID:7026235]
  Authors
Garrido-Peritierra A, Cooper RA
  Title
Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli.
  Journal
Eur J Biochem 117:581-4 (1981)
DOI:10.1111/j.1432-1033.1981.tb06377.x
Reference
2
  Authors
Johnson WH Jr, Hajipour G, Whitman CP.
  Title
Characterization of a dienol intermediate in the 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase reaction.
  Journal
J Am Chem Soc 114:11001-11003 (1992)
Reference
3
  Authors
Johnson WH Jr, Hajipour G, Whitman CP.
  Title
Stereochemical studies of 5-(carboxymethyl)-2-hydroxymuconate isomerase and 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase from Escherichia coli C: mechanistic and evolutionary implications.
  Journal
J Am Chem Soc 117:8719-8726 (1995)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.68
IUBMB Enzyme Nomenclature: 4.1.1.68
ExPASy - ENZYME nomenclature database: 4.1.1.68
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.68
BRENDA, the Enzyme Database: 4.1.1.68

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Protein sequence (656)   
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   PDBSTR (4)   
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   RefSeq(nuc) (15)   
   GenBank (510)   
   EMBL (507)   
Protein domain (4)   
   InterPro (4)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (2125)   

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