KEGG   ENZYME: 4.1.1.74
Entry
EC 4.1.1.74                 Enzyme                                 
Name
indolepyruvate decarboxylase;
indol-3-yl-pyruvate carboxy-lyase;
3-(indol-3-yl)pyruvate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]
Reaction(IUBMB)
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 [RN:R01974]
Reaction(KEGG)
R01974
Substrate
3-(indol-3-yl)pyruvate [CPD:C00331]
Product
2-(indol-3-yl)acetaldehyde [CPD:C00637];
CO2 [CPD:C00011]
Comment
Thiamine diphosphate- and Mg2+-dependent. More specific than EC 4.1.1.1 pyruvate decarboxylase
History
EC 4.1.1.74 created 1999
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K04103  indolepyruvate decarboxylase
Genes
STYSTY2646
STTt0452
SEXSTBHUCCB_4850
SENTTY21A_02305
STMSTM2405
SEOSTM14_2958
SEVSTMMW_24291
SEYSL1344_2373
SEMSTMDT12_C24280
SEJSTMUK_2436
SEBSTM474_2506
SEFUMN798_2596
SETUSTU288_08415
SETCCFSAN001921_04750
SENRSTMDT2_23731
SENDDT104_24631
SENICY43_12870
SEENSE451236_18240
SPTSPA0455
SEKSSPA0422
SPQSPAB_00555
SEISPC_1250
SECSCH_2408(dciP)
SEHSeHA_C2663
SHBSU5_03012
SENHCFSAN002069_19740
SEEHSEEH1578_21365
SEESNSL254_A2597
SENNSN31241_35150
SEWSeSA_A2639
SEASeAg_B2548
SENSQ786_11880
SEGSG2441
SELSPUL_0473
SEGASPUCDC_0473
SETSEN2391
SENAAU38_12100
SENOAU37_12115
SENVAU39_12115
SENQAU40_13575
SENLIY59_12435
SENJCFSAN001992_21525
SEEBSEEB0189_007540
SENBBN855_24940
SENEIA1_12005
SENCSEET0819_19470
SESSARI_00479
SBGSBG_2213
SBZA464_2540
SBVN643_10720
SALZEOS98_06945
ENCECL_03728
ENLA3UG_16365
ECLGEC036_31850
ECLEECNIH2_16335
ECLNECNIH4_06815
ECLIECNIH5_15275
ECLXLI66_15680
ECLYLI62_17180
ECLZLI64_15110
ECLOENC_38590
EHMAB284_09740
EXFBFV63_15500
ECLAECNIH3_15365
ECLCECR091_15300
EAUDI57_03295
EKBBFV64_16045
ENOECENHK_15930
EECEcWSU1_03228(ipdC)
ELGBH714_12275
ECANCWI88_06420(ipdC)
ERNBFV67_15815
ECLSLI67_017200
ECHGFY206_17670(ipdC)
ESHC1N69_16200(ipdC)
ENTEnt638_2923
EASEntas_3129
ENRH650_07700
ENXNI40_015950
ENFAKI40_1502
LNICWR52_19090(ipdC)
EBGFAI37_13135(ipdC)
ENDA4308_20595
ENZG0034_16545(ipdC)
ENSHWQ15_01260(ipdC)
ENKLOC22_03820(ipdC)
ESAESA_00851
CSKES15_1112(ipdC)
CSZCSSP291_04140
CSJCSK29544_02057
CCONAFK62_14225
CDMAFK67_14625
CSIP262_01617
CMJAFK66_005195
CUIAFK65_14100
CMWAFK63_04175
CTUCTU_29970(ipdC)
KPNKPN_02740
KPUKP1_3993
KPMKPHS_38120
KPPA79E_1361
KPHKPNIH24_09625
KPZKPNIH27_18210
KPVKPNIH29_19025
KPWKPNIH30_19245
KPYKPNIH31_18445
KPGKPNIH32_19575
KPCKPNIH10_18585
KPQKPR0928_18605
KPTVK055_4773(ipdC)
KPOKPN2242_16790
KPRKPR_1964(ipdC)
KPJN559_1511
KPID364_13960
KPAKPNJ1_01595
KPSKPNJ2_01565
KPXPMK1_00237(ipdC)
KPBFH42_09815
KPNEKU54_007350
KPNULI86_07355
KPNKBN49_3956(ipdC)
KVAKvar_1310
KPEKPK_1400(ipdC)
KPKA593_03955
KVDKR75_01250
KVQSP68_07780
KOXKOX_26745
KOEA225_4252
KOYJ415_10885
KOMHR38_24875
KMIVW41_16130
KOKKONIH1_20955
KOCAB185_15375
KQUAVR78_23265
EAEEAE_00275
EARCCG28866
KQVB8P98_08020
KLLBJF97_20915
KLWDA718_08065
KARLGL98_06985
KGRJJJ10_07820
RORRORB6_00760
RONTE10_20660
RPLNB1209_06820
RAODSD31_07120
RTGNCTC13098_01877(ipdC)
REEelectrica_01381(ipdC)
CROROD_28081
CKOCKO_00409
CFDCFNIH1_23390
CBRAA6J81_24390
CWECO701_05905
CYOCD187_07330
CPOTFOB25_18495
CFQC2U38_17710
CSEDJY391_07050
CAMAF384_13285
CAFAL524_10160
CIFAL515_16230
CFARCI104_17990
CIRC2U53_28235
CPARCUC49_12300
CTELGBC03_12025
CITZE4Z61_23790
CARSE1B03_18930
EBTEBL_c11250
CNTJT31_18750
CEMLH23_22180
CENLH86_20710
CLAPNCTC11466_01206(ipdC)
PGELG71_11480
ESCEntcl_1355
KLEAO703_15060
KSAC813_22760
KORAWR26_07600
KRDA3780_16360
KPSEIP581_15955
KIENCTC12125_00318(ipdC)
KASKATP_12520
LAXAPT61_06465
LEIC2U54_21570(ipdC)
LEHC3F35_18455(ipdC)
LEEDVA44_06580(ipdC)
LERGNG29_16180(ipdC)
LEAGNG26_16025(ipdC)
LAZA8A57_15055
LEFLJPFL01_2968
LEWDAI21_11595(ipdC)
BUFD8682_22045
BAGEBADSM9389_11760
AHNNCTC12129_01441(ipdC)
YREHEC60_11310
SGOEA8O29_006725
IZHFEM41_22835
PSHISAMEA2665130_1032(ipdC)
PSGCG163CM_02450(ipdC)
EBFD782_1263
EBUCUC76_22595
PSTSE05_18610
YENYE1222(ipdC)
YEPYE105_C2890
YEYY11_00891
YEWCH47_624(ipdC)
YETCH48_396
YEFFORC2_1242
YEEYE5303_09771(ipdC)
YALAT01_1826 AT01_3659
YROCH64_1327
YAKACZ76_03060
YMADA391_06555
YHID5F51_15485
YCAF0T03_06850
YMOHRD69_19045
SMARSM39_3023
SMACSMDB11_2815
SMWSMWW4_v1c35330
SPESpro_3412
SRRSerAS9_3605
SRLSOD_c33270(ipdC)
SRYM621_18085
SPLYQ5A_018035(ipdC_2)
SRSSerAS12_3606
SRASerAS13_3607
SMAFD781_3193
SLQM495_17545
SERFL085_11020 L085_12715 L085_13395
SERSSERRSCBI_17135
SFWWN53_26400
SFGAV650_22465
SRZAXX16_1876
SERMCLM71_16870
SQUE4343_23680
SFJSAMEA4384070_3544(ipdC_2)
SOFNCTC11214_03262(ipdC_2)
SSURATE40_014285
SURIJ0X03_06375
SRHZFO014_17375
SFOZ042_04065
RAHRahaq_1125
RAQRahaq2_1203
RAAQ7S_05405
ROXBV494_00920
RVCJ9880_13470
GQUAWC35_19130
EAMEGXP68_06180
RBADH2866_01975
ECAECA3605(ipdC)
PATREV46_17890
PATOGZ59_36300(ipdC)
PCTPC1_3426
PCCPCC21_034320
PCVBCS7_17265
PPOABJK05_12135
PBRAB5S52_04525
PPUJE2566_17245(ipdC)
PARII2D83_04345(ipdC)
PVZOA04_36950(ipdC)
PPAVLOZ86_04685(ipdC)
DDCDd586_3014
CEDLH89_04805
DFNCVE23_07930
BGJAWC36_00415
EAMEAMY_2469(pdc3)
EAYEAM_2375(ipdC)
ETAETA_11130(ipdC)
EPYEpC_11610(ipdC)
EPREPYR_01238(pdc)
EBIEbC_32520(ipdC)
ERJEJP617_35260(ipdC)
EPECI789_02120
ERWIGN242_05845
PAMPANA_2745(ipdC)
PLFPANA5342_1305(ipdC)
PAJPAJ_2029(ipdC)
PAQPAGR_g1280
PVAPvag_2180(ipdC)
PAGGAL522_17970(ipdC)
PAOPat9b_2818
KLNLH22_08515
PANTPSNIH1_00855
PANPPSNIH2_03830
PAGCBEE12_01535
PALHB1H58_13165
PANSFCN45_13640
PEYEE896_05575(ipdC)
PDISD8B20_12140
PERLAC65_11385
PGZC2E15_15295
PCDC2E16_14980
MINTC7M51_02237(ipdC)
MTHIC7M52_00620(ipdC)
TCIA7K98_17870
PMRPMI0845(ipdC)
PMIBBB2000_0963(ipdC)
PVLAOB99_06655
PVGCRN77_14965
PHAUPH4a_13540
PROTBTA34_05370
PCOLF1325_07190
PCIBF9282_07080
PPEEI6G31_02940
PSIS70_05510 S70_19930
PSXDR96_214 DR96_2898
PSTABGK56_01980 BGK56_08375
PRGRB151_020410(ipdC)
PALACO695_08990 CO695_09005
PHEINCTC12003_00975(ipdC_1) NCTC12003_02564(ipdC_2)
PRQCYG50_07000 CYG50_21130
PRJNCTC6933_03065(ipdC_1) NCTC6933_03068(ipdC_2)
PVCG3341_04665 G3341_11360
MMKMU9_3137
EICNT01EI_0305 NT01EI_1772
ETRETAE_1930
ETDETAF_1742
ETEETEE_4006(ipdC)
ETCETAC_08820
EDWQY76_10580
EDLAAZ33_09865
EHOA9798_15120
HAVAT03_07360
HPARAL518_18225
OPODSM2777_12635
DYEEO087_06490
VNIVIBNI_B0089
POIBOP93_20470
PENPSEEN2115
PSAMHU731_009640
PANHHU763_022815
PMAMKSS90_10950
PAGRE2H98_15195
SDNSden_1376
SAZSama_1025
SSESsed_0171
SWPswp_0601
SKHSTH12_00564(ipdC)
SLITJQC75_04935
SEURFM038_000935
IDICWC33_04800
IABK5X84_00755
CPSCPS_0688
PRRAT705_06545
PLZS4054249_14100 S4054249_16175
PALNB0W48_00215
PPISB1L02_22865
PSENPNC201_21925(ipdC)
PVBJ5X90_08120 J5X90_18170
LALAT746_07025
CATEC2869_18270
SAGAM5M_04875
FTUFTT_1744c(ipdC)
FTQRO31_2075
FTFFTF1744c(ipdC)
FTWFTW_1982
FTRNE061598_10155
FTTFTV_1661(ipdC)
FTGFTU_1746(ipdC)
FTLFTL_0006
FTSF92_00035
FTOX557_00040
FTCDA46_736
FTVCH67_257
FTZCH68_2141
FTMFTM_1730(idpC)
FTNFTN_0116(ipdC)
FTXAW25_84
FTDAS84_598
FTYCH70_10
FCFFNFX1_0108
FCNFN3523_0100
FHIFSC454_00480
FPHFphi_0711 Fphi_1598
FPTBZ13_1316
FPIBF30_920
FPMLA56_1459
FPXKU46_635
FPZLA55_89
FPJLA02_567
FRTF7308_0106
FRXF7310_00570
FRCKX01_410
FADCDH04_05840
FMIF0R74_08965
FSRKQR59_00530
TSYTHSYN_15535
RHHE0Z06_09145
THIPN838_27840 N838_29260
HCHHCH_01981
HAHEENC22_20920
SUTRL0B52_07745(ipdC)
SEDSAAY24_06235
PDIOPDMSB3_1977.1
BOJCBF45_08145
KGYEHF36_08290
RFRRfer_0518
COFFOZ74_12250(ipdC)
SIMPC6571_06705(ipdC)
MNRACZ75_02305
MASZC9I28_16430(ipdC)
MASYDPH57_05430(ipdC)
MFLAGO485_02350(ipdC)
UPLDSM104440_01061(ipdC)
ARESIWH25_13915(ipdC)
EBAebA6545(pdc)
ABREpbN1_40400(pdC)
APETToN1_46880(pdc)
AZAAZKH_2996(ipdC)
AZIAzCIB_1933
AZDCDA09_11830(ipdC)
TMZTmz1t_0101
TCLTchl_0074
TAKTharo_0060
APPCAP2UW1_2653
DVMDvMF_0027
DMADMR_26260
DCBC3Y92_12130
DDEDde_2331
DSADesal_2664
DASDaes_0883
DPSDP2330
LLUAKJ09_08048
KMNHW532_21720(ipdC)
SMKSinme_5681
SMQSinmeB_5928
SMDSmed_5992 Smed_6051
RETRHE_PF00449
RECRHECIAT_PC0000672
RELREMIM1_PF00428
REPIE4803_PC00499
REIIE4771_PD00509
RLURLEG12_10425
RGARGR602_PC00349
RHNAMJ98_PE00527
RPHAAMC79_PD00665
RHKKim5_PC00457
REZAMJ99_PD00527
RHIDFFM81_025020
RLNJ0663_24040
RBANJ2J98_22780
RRGJ3P73_25215
BRABRADO7016(ipdC)
BBTBBta_0512(ipdC)
AOLS58_04790
BROBRAD285_7156(ipdC)
BGZXH91_10085
RPARPA3116(ipdC)
RPBRPB_2425
RPDRPD_3027
RPTRpal_3526
RPXRpdx1_2308
SNOSnov_3860
STARG3545_10560
BIDBind_1794
CMBCSW64_09035
PAMOBAR1_13915(ipdC)
SPHSETR14_13725
ERRDVR09_08065(ipdC)
ABGAsbog_00347
BOBGN304_01255 GN304_01565
PARZDTQ13_05850
ABSAZOBR_40354(ipdC)
ABQABAZ39_11295
ABFAMK58_11540
AZTTSH58p_08865(ipdC)
NCBC0V82_11605
RRURru_A2719
RRFF11_13965
DVNHQ394_02155
HTLHPTL_0792
BCGBCG9842_B2896
BTNBTF1_09505
BWEBcerKBAB4_2434
BWWbwei_2395(PDC5)
BMYCDJ92_4749
BWDCT694_29840
BNTGSN03_12745
BLEBleG1_3106
BSJUP17_04570
BMURABE28_004740
SALEEPH95_05810
BVJI5776_11475
STEAC0679_01880
SSCZRN70_02275
SLZB5P37_04325
SCHRDWB92_02035
SFFFOB90_05805
PBVAR543_06930
PYGAWM70_15780
COHNKCTCHS21_12950(pdc)
SACAFFV09_15190
CPASClopa_0520
CPATCLPA_c04400(kdc)
CPAECPAST_c04400(kdc)
MPEMYPE6890(MYPE6890)
MSTOMSTO_33270
MSAKMSAS_54240
MKUI2456_01155
MAUUNCTC10437_03502(pdc)
MTYMTOK_57060(pdc1)
MSEIMSEDJ_11710
SGVB1H19_03900
SFYGFH48_00745
SRIMCP984_14945
SBROGQF42_35885
SCALI6J39_02285
SACTDMT42_01490
ACITHPK19_08900
NGVCDO52_11105
NGNLCN96_39405
FRIFraEuI1c_3511
KRAKrad_0182
SAQSare_0838
AMSAMIS_17220
SYGsync_1491
SYXSynWH7803_0869(pdc)
SYNDKR52_11410
CANCyan10605_1896
CAPCLDAP_36720
SACISinac_1424
AGVOJF2_34230(ipdC_2)
PCORKS4_35060(ipdC)
CPICpin_1754
CHIHGWR21_24215
ARACE0W69_007350
MUCMuYL_0601
FJOFjoh_3836
AQBD1818_21015
AFLAFHG64_17570
MBAMbar_A1429
MBYMSBRM_0475
MBWMSBRW_3298
MBARMSBR2_1907
MBAKMSBR3_2046
MACMA_0594(ipdC)
MVCMSVAZ_0537
MEKMSKOL_0516
MTHRMSTHT_2109
MTHEMSTHC_1175
MHORMSHOH_3634
MFZAOB57_005405
 » show all
Reference
1  [PMID:7766676]
  Authors
Koga J.
  Title
Structure and function of indolepyruvate decarboxylase, a key enzyme in indole-3-acetic acid biosynthesis.
  Journal
Biochim Biophys Acta 1249:1-13 (1995)
DOI:10.1016/0167-4838(95)00011-I
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.74
IUBMB Enzyme Nomenclature: 4.1.1.74
ExPASy - ENZYME nomenclature database: 4.1.1.74
BRENDA, the Enzyme Database: 4.1.1.74
CAS: 9074-92-4

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